Aim: The aim of this study was to investigate whether hematological parameters play a significant role in the relationship between hematological parameters and seizure occurrence in children with febrile seizures (FS) by comparing them to a healthy control group with no fever or seizures.
Materials and Methods: One-hundred forty-one patients diagnosed with FS and with available a complete blood count results and a control group of 143 children were finally enrolled.
Results: The study group consisted of 141 patients, 57 girls (40.4%) and 84 boys (59.6%) (M/F=1.4). Mean age at the time of first FS was 22.89 ± 13.95 months. Ninety-two (65.2%) of the study group were diagnosed with simple FS, 32 (22.7%) with complex FS, and 17 (12.1%) with febrile status epilepticus (FSE).
Conclusion: Since our neutrophil, lymphocyte, eosinophil, and mean platelet volume (MPV) results were statistically significant in patients with FS, it is thought that these markers may represent potential predictive parameters in that condition.
Ethical approval for the study was obtained from the institutional review board (no.2022/7-53). This study conformed to the Helsinki Declaration.
This study was not funded by any supporter.
Amaç: Bu çalışmanın amacı, ateşli nöbet (FN) geçiren çocuklarda hematolojik parametreler ile nöbet oluşumu arasındaki ilişkide hematolojik parametrelerin önemli bir rol oynayıp oynamadığını, ateşi ve nöbeti olmayan sağlıklı bir kontrol grubu ile karşılaştırarak araştırmaktır.
Gereç ve Yöntem: FN tanısı almış ve hemogram sonuçları bulunan 141 hasta ve 143 sağlıklı çocuk kontrol grubu olarak çalışmaya dahil edildi.
Bulgular: Çalışma grubu 57 Kız (%40,4), 84 Erkek (59,6) olmak üzere 141 hastadan (E/K=1,4) oluşmaktadır. Hastaların ilk FN geçirme yaş aralığı 22,89 ± 13,95 aydır. Hasta grubunun 92’si (%65,2) basit FK, 32’si (%22,7) komplike FN ve 17’si (%12,1) febril status epileptikus (FSE) tanısı almıştı.
Sonuç: Çalışmamızda FN’li hastalarda nötrofil, lenfosit, eozinofil ve ortalama trombosit hacmi (MPV) sonuçlarının istatistiksel olarak anlamlı tespit edilmesi nedeniyle bu belirteçlerin FN’de öngörücü parametreler olabileceği düşünülmektedir.
Ethical approval for the study was obtained from the institutional review board (no.2022/7-53). This study conformed to the Helsinki Declaration.
This study was not funded by any supporter.
Primary Language | English |
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Subjects | Pediatric Neurology |
Journal Section | Research Article |
Authors | |
Publication Date | December 31, 2023 |
Submission Date | July 30, 2023 |
Acceptance Date | December 8, 2023 |
Published in Issue | Year 2023 Volume: 9 Issue: 3 |