Research Article
Examination of the Topography and Morphometry of Hypophysis (Glandula pituitaria) by Computed Tomography in New Zealand Rabbits
Abstract
The aim of this study is to determine the morphometry of hypophysis of the New Zealand rabbit by using the computed tomography images and its topography according to the anatomical structures in the cavum cranii. For this purpose, the head of 12 (6 female, 6 male) New Zealand Rabbits was scanned in a prone position by using Multi-Detector Computed Tomography. Three-dimensional modeling of the images obtained was performed. Morphometric analysis of the hypophysis, the three-dimensional modeling of which was performed, and its topographic measurements were taken according to the adjacent structures. When the data were examined, it was found that protuberantia occipitalis externa value was statistically significant in terms of sexes (P<0.05). There was no statistically significant difference between other data in terms of sexes (P>0.05). When the correlation analysis was examined, positive correlations between the gland volume and volume of cavum cranii (P<0.01) and between volume and surface area of cavum cranii were detected (P<0.05). Consequently, it is thought that the data of the study would contribute to the operative and experimental studies to be conducted on the region by determining the morphometry and topography of the hypophysis in New Zealand rabbits.
References
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- 2. Poyraz Ö., 2000. Laboratuvar hayvanları bilimi. Kardelen ofset, Ankara.
- 3. Demirsoy A., 1992. Yaşamın temel kuralları. Omurgalılar (Sürüngenler, Kuşlar ve Memeliler). 1. st, Meteksan, Ankara.
- 4. Mapara M., Thomas BS., Bhat KM., 2012. Rabbit as an animal model for experimental research. Dent Res J, 9, 111-118.
- 5. Dyce KM., Sack WO., Wensing CJG., 2002. Textbook of veterinary anatomy. Third Edition, Philadelphia, United States, Saunders.
- 6. Taner D., 2014. Fonksiyonel nöroanatomi. 12st ed., ODTÜ Yayıncılık, Ankara.
- 7. Yaman K., 2009. Fizyoloji. 4.st ed., Ezgi Kitabevi, Bursa.
- 8. Noyan A., 2004. Yaşamda ve hekimlikte fizyoloji. Meteksan, Ankara.
- 9. Van der Vlugt-Meijer RH., Meij BP., Voorhout G., 2006. Intraobserver and interobserver agreement, reproducibility, and accuracy of computed tomographic measurements of pituitary gland dimensions in healthy dogs. Am J Vet Res, 67, 1750-1755.
- 10. Kizilkanat ED., Boyan N., Tekdemir I., Soames R., Oguz O., 2007. Surgical importance of the morphometry of the anterior and middle cranial fossae. Neurosurg Q, 17, 60-63.
- 11. Prokop M., 2003. General principles of MDCT. Eur J Radiol, 45, 4-10.
- 12. Kalra MK., Maher MM., Toth TL., Hamberg LM., Blake MA., Shepard JA., Saini S., 2004. Strategies for CT radiation dose optimization. Radiology, 230, 619-628.
- 13. International Committee on Veterinary Gross Anatomical Nomenclature, 2017. Nomina anatomica veterinaria. WAVA.
- 14. Kwan V., Quesenberry K., Le Roux AB., 2020. Mensuration of the rabbit pituitary gland from computed tomography. Vet Radiol Ultrasound, 61, 322-328.
- 15. Turamanlar O., Horata E., Gökaslan ÇÖ., Ertekin T., 2019. Is there any effect of the seasonal changes on the pituitary gland morphometry? BSJ Health Sci, 2, 1-4.
- 16. Raghuprasad MS., Manivannan M., 2018. Volumetric and morphometric analysis of pineal and pituitary glands of an Indian inedial subject. Ann Neurosci, 25, 279-288.
- 17. Uzun ND., Yonguç GN., Durmaz MO., Karabekir HS., Mas NG., 2018. Morphometric analysis of hypophyseal fossa related structure; in terms of surgical approach. Kocaeli Med J, 7, 130-134.
- 18. Han X., Xiu J., Huang Z., Zhang J., Zhang Z., Dong Y., Yuan X., Liu Q., 2014. Three‑dimensional magnetic resonance volumetry of the pituitary gland is effective in detecting short stature in children. Exp Ther Med, 8, 551-556.
- 19. Polat SÖ., Öksüzler FY., Öksüzler M., Uygur AG., Yücel AH., 2020. The determination of the pituitary gland, optic chiasm, and intercavernous distance measurements in healthy subjects according to age and gender. Folia Morphol, 79, 28-35.
- 20. Müllhaupt D., Augsburger H., Schwarz A., Fischer G., Kircher P., Hatt JM., Ohlerth S., 2015. Magnetic resonance imaging anatomy of the rabbit brain at 3T. Acta Vet Scand, 57, 1-9.
- 21. Nadimi S., Molazem M., Jarolmasjed S., Esmaili Nejad MR., 2018. Volumetric evaluation of pituitary gland in dog and cat using computed tomography. Vet Res Forum, 9, 337-341.
Yeni Zelanda Tavşanlarında Hipofiz Bezi’nin (Gandula pituitaria) Topografisi ve Morfometrisinin Bilgisayarlı Tomografi ile İncelenmesi
Abstract
Çalışmada, Yeni Zelanda tavşanında hipopysis’in bilgisayarlı tomografi görüntüleri kullanılarak, morfometrisinin ve cavum cranii’deki anatomik yapılara göre topografisinin belirlenmesi amaçlandı. Bu amaçla çalışmada 12 adet (6 dişi, 6 erkek) Yeni Zelanda tavşanının, cranium bölgesi, prone pozisyonda, Multi Detector Computed Tomography kullanılarak, 0,625 mm kesit kalınlığında tarandı. Elde edilen görüntülerin üç boyutlu modellemeleri yapıldı. Üç boyutlu modellemeleri yapılan hipophysis bezinin morfometrik analizi ve komşuluğu bulunan yapılara göre topografik ölçümleri alındı. Veriler incelendiğinde protuberantia occipitalis externa değerinin cinsiyetler açısından istatistiki olarak anlamlı olduğu belirlendi (P<0.05). Diğer veriler arasında cinsiyetler arasında istatistiki olarak anlamlı bir fark belirlenmedi (P>0.05). Korelasyon analizi incelendiğinde ise, bez hacmi ile cavum cranii hacmi arasında (P<0.01) ve cavum cranii hacmi ile cavum cranii yüzey alanı arasında (P<0.05) pozitif korelasyonlar tespit edildi. Sonuç olarak çalışma verilerinin, Hypophysis bezinin Yeni Zelanda tavşanlarındaki morfometresini ve topografisini belirleyerek bölge üzerinde yapılacak operatif ve deneysel çalışmalara katkı sağlayacağı düşünülmektedir.
References
- 1. Mous McLaughlin CA., Chiasson RB., 1990. Laboratory anatomy of the rabbit. McGraw-Hill companies, Toronto.
- 2. Poyraz Ö., 2000. Laboratuvar hayvanları bilimi. Kardelen ofset, Ankara.
- 3. Demirsoy A., 1992. Yaşamın temel kuralları. Omurgalılar (Sürüngenler, Kuşlar ve Memeliler). 1. st, Meteksan, Ankara.
- 4. Mapara M., Thomas BS., Bhat KM., 2012. Rabbit as an animal model for experimental research. Dent Res J, 9, 111-118.
- 5. Dyce KM., Sack WO., Wensing CJG., 2002. Textbook of veterinary anatomy. Third Edition, Philadelphia, United States, Saunders.
- 6. Taner D., 2014. Fonksiyonel nöroanatomi. 12st ed., ODTÜ Yayıncılık, Ankara.
- 7. Yaman K., 2009. Fizyoloji. 4.st ed., Ezgi Kitabevi, Bursa.
- 8. Noyan A., 2004. Yaşamda ve hekimlikte fizyoloji. Meteksan, Ankara.
- 9. Van der Vlugt-Meijer RH., Meij BP., Voorhout G., 2006. Intraobserver and interobserver agreement, reproducibility, and accuracy of computed tomographic measurements of pituitary gland dimensions in healthy dogs. Am J Vet Res, 67, 1750-1755.
- 10. Kizilkanat ED., Boyan N., Tekdemir I., Soames R., Oguz O., 2007. Surgical importance of the morphometry of the anterior and middle cranial fossae. Neurosurg Q, 17, 60-63.
- 11. Prokop M., 2003. General principles of MDCT. Eur J Radiol, 45, 4-10.
- 12. Kalra MK., Maher MM., Toth TL., Hamberg LM., Blake MA., Shepard JA., Saini S., 2004. Strategies for CT radiation dose optimization. Radiology, 230, 619-628.
- 13. International Committee on Veterinary Gross Anatomical Nomenclature, 2017. Nomina anatomica veterinaria. WAVA.
- 14. Kwan V., Quesenberry K., Le Roux AB., 2020. Mensuration of the rabbit pituitary gland from computed tomography. Vet Radiol Ultrasound, 61, 322-328.
- 15. Turamanlar O., Horata E., Gökaslan ÇÖ., Ertekin T., 2019. Is there any effect of the seasonal changes on the pituitary gland morphometry? BSJ Health Sci, 2, 1-4.
- 16. Raghuprasad MS., Manivannan M., 2018. Volumetric and morphometric analysis of pineal and pituitary glands of an Indian inedial subject. Ann Neurosci, 25, 279-288.
- 17. Uzun ND., Yonguç GN., Durmaz MO., Karabekir HS., Mas NG., 2018. Morphometric analysis of hypophyseal fossa related structure; in terms of surgical approach. Kocaeli Med J, 7, 130-134.
- 18. Han X., Xiu J., Huang Z., Zhang J., Zhang Z., Dong Y., Yuan X., Liu Q., 2014. Three‑dimensional magnetic resonance volumetry of the pituitary gland is effective in detecting short stature in children. Exp Ther Med, 8, 551-556.
- 19. Polat SÖ., Öksüzler FY., Öksüzler M., Uygur AG., Yücel AH., 2020. The determination of the pituitary gland, optic chiasm, and intercavernous distance measurements in healthy subjects according to age and gender. Folia Morphol, 79, 28-35.
- 20. Müllhaupt D., Augsburger H., Schwarz A., Fischer G., Kircher P., Hatt JM., Ohlerth S., 2015. Magnetic resonance imaging anatomy of the rabbit brain at 3T. Acta Vet Scand, 57, 1-9.
- 21. Nadimi S., Molazem M., Jarolmasjed S., Esmaili Nejad MR., 2018. Volumetric evaluation of pituitary gland in dog and cat using computed tomography. Vet Res Forum, 9, 337-341.
There are 21 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Araştırma Makaleleri |
| Authors | |
| Publication Date | October 31, 2021 |
| Published in Issue | Year 2021 Volume: 16 Issue: 2 |