Abstract
The aim of this study is to report clinical, Magnetic Resonance Imaging (MRI), surgical and histopathologic findings of vertebral osteosarcoma in a cat. 6-year-old mix cat was presented to the clinic with a symptom of progressive tetraplegia for 3 months. According to the neurologic examination, it was thought that the lesion could be between C6-T2 vertebrae. With respect to the neurologic examination, radiographic findings showed a radioluscent area between C6-C7 vertebrae. In addition, MRI findings defined an extramedullary mass included lamina and processus spinosus of C7. Surgery was performed and tumor was extirpated. According to the histopathologic examination, the tumor was confirmed as osteosarcoma. Chemotherapy protocol was applied to the patient 5 times between 21 days interval. The cat survived for 18 months. Combination of surgical intervention and adjuvant therapy is suggested for the treatment protocol for vertebral osteosarcoma.
Keywords
References
- Heldmann E, Anderson MA, Wagner-Mann C. (2000). Feline Osteosarcoma: 145 cases (1990–1995). J Am Anim Hosp Assoc. 36(6): 518–521.
- Bitetto WV, Patnaik AK, Schrader SC, Mooney SC. (1987). Osteosarcoma in Cats: 22 cases (1974–1984). J Am Vet Med Assoc. 190(1): 91–93.
- Dimopoulou M, Kirpensteijn J, Moens H, Kik M. (2008). Histologic Prognosticators in Feline Osteosarcoma: A Comparison with Phenotypically Similar Canine Osteosarcoma. Vet Surg. 37(5): 466–471
- Okada M, Kitagawa M, Nagasawa A, Itou T, Kanayama K, Sakai T. (2009). Magnetic Resonance Imaging and Computed Tomography Findings of Vertebral Osteosarcoma in a cat. J Vet Med Sci. 71(4): 513–517
- Giuliano A, Busscher VD, Lu DDA, Ng KWL, Beatty JA. (2022).Successful Treatment of Vertebral Osteosarcoma in a Cat Using Marginal Surgical Excision and Chemotherapy. Vet Sci. 9(7): 315-323.
- Dixon A, Chen A, Rossmeisl JH ve ark. (2019). Surgical Decompression, with or without Adjunctive Therapy, for Palliative Treatment of Primary Vertebral Osteosarcoma in Dogs. Vet Comp Oncol. 17(4): 472–478.
- Nakano Y, Kagawa Y, Shimoyama Y ve ark. (2021). Outcome of Appendicular or Scapular Osteosarcoma Treated by Limb Amputation in Cats: 67 cases (1997-2018). J Am Vet Med Assoc. 260(S1):S24-S28
- Liu SK, Dorfman HD, Patnaik AK. (1974). Primary and Secondary Bone Tumours in the Cat. J Small Anim Pract. 15(3): 141–156.
- Nakata K, Miura H, Sakai H ve ark. (2017).Vertebral Replacement for the Treatment of Vertebral Osteosarcoma in a Cat. J Vet Med Sci.79 (6): 999-1002.
- Saam DE, Liptak JM, Stalker MJ, Chun R. (2011). Predictors of Outcome in Dogs Treated with Adjuvant Carboplatin for Appendicular Osteosarcoma: 65 cases (1996-2006). J Am Vet Med Assoc. 238(2): 195-206
Abstract
Bu rapor, bir kedide vertebral osteosarkoma’nın klinik, manyetik rezonans görüntüleme, cerrahi ve histopatolojik sonuçlarını bildirmektedir. Üç ay önce başlayan progresif seyirli tetrapleji şikayeti olan 6 yaşlı-dişi-melez kedi konu edildi. Nörolojk muayene sonucunda, lezyonun C6-T2 vertebraları arasında olabileceği düşünüldü. Bunun üzerine yapılan radyografik incelemede; C6-C7 vertebraları arasında radyolüsen bir alana rastlandı. Manyetik Rezonans Görüntülemede (MRG), C7’nin lamina ve prosessus spinozusunu kapsayan ekstradural yerleşimli kitle teşhis edildi. Cerrahi müdahale ile uzaklaştırılan kitlenin histolojik incelemesinde osteosarkom tanısı kondu. Operasyon sonrası süreçte adjuvan tedavi amacıyla; 21 gün arayla toplam 5 doz Karboplatin uygulandı. Hasta 18 ay yaşadı. Vertebral osteosarkomların tedavisinde temiz cerrahi alan ve adjuvan tedavi önerilir bulundu.
Keywords
References
- Heldmann E, Anderson MA, Wagner-Mann C. (2000). Feline Osteosarcoma: 145 cases (1990–1995). J Am Anim Hosp Assoc. 36(6): 518–521.
- Bitetto WV, Patnaik AK, Schrader SC, Mooney SC. (1987). Osteosarcoma in Cats: 22 cases (1974–1984). J Am Vet Med Assoc. 190(1): 91–93.
- Dimopoulou M, Kirpensteijn J, Moens H, Kik M. (2008). Histologic Prognosticators in Feline Osteosarcoma: A Comparison with Phenotypically Similar Canine Osteosarcoma. Vet Surg. 37(5): 466–471
- Okada M, Kitagawa M, Nagasawa A, Itou T, Kanayama K, Sakai T. (2009). Magnetic Resonance Imaging and Computed Tomography Findings of Vertebral Osteosarcoma in a cat. J Vet Med Sci. 71(4): 513–517
- Giuliano A, Busscher VD, Lu DDA, Ng KWL, Beatty JA. (2022).Successful Treatment of Vertebral Osteosarcoma in a Cat Using Marginal Surgical Excision and Chemotherapy. Vet Sci. 9(7): 315-323.
- Dixon A, Chen A, Rossmeisl JH ve ark. (2019). Surgical Decompression, with or without Adjunctive Therapy, for Palliative Treatment of Primary Vertebral Osteosarcoma in Dogs. Vet Comp Oncol. 17(4): 472–478.
- Nakano Y, Kagawa Y, Shimoyama Y ve ark. (2021). Outcome of Appendicular or Scapular Osteosarcoma Treated by Limb Amputation in Cats: 67 cases (1997-2018). J Am Vet Med Assoc. 260(S1):S24-S28
- Liu SK, Dorfman HD, Patnaik AK. (1974). Primary and Secondary Bone Tumours in the Cat. J Small Anim Pract. 15(3): 141–156.
- Nakata K, Miura H, Sakai H ve ark. (2017).Vertebral Replacement for the Treatment of Vertebral Osteosarcoma in a Cat. J Vet Med Sci.79 (6): 999-1002.
- Saam DE, Liptak JM, Stalker MJ, Chun R. (2011). Predictors of Outcome in Dogs Treated with Adjuvant Carboplatin for Appendicular Osteosarcoma: 65 cases (1996-2006). J Am Vet Med Assoc. 238(2): 195-206
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Case Report |
| Authors | |
| Early Pub Date | June 24, 2023 |
| Publication Date | June 30, 2023 |
| Acceptance Date | March 31, 2023 |
| Published in Issue | Year 2023 Volume: 16 Issue: 1 |
