Abstract
In this report, clinical, radiological, macroscopic and histopathological findings of apocrine sweat gland adenocarcinoma are presented in a 13-year-old male tabby cat. In clinical examination, soft tissue masses were detected in the caudal abdomen and left tuber coxae. Upon radiological examination, subcutaneous masses with the appearence of soft tissue contrast were detected and the masses were surgically removed under general anesthesia. The sizes of the masses were approximately 2x2x3 cm in the caudal abdomen and approximately 1x1x2 cm in the tuber coxae region. The cross-section of the mass was whitish-yellow in color. After the masses were fixed in 10% formaldehyde solution, a routine histopathology procedure was applied. In histopathological examination, apocrine sweat glands in a cystic structure and extensions from the center of the cyst to the lumen were determined, and anisonucleosis, anisocytosis and anaplastic cells with giant nuclei were observed in the epithelial cells of the gland facing the lumen. A diagnosis of papillary-cystic type apocrine sweat gland adenocarcinoma was made with these findings.
Keywords
Supporting Institution
-
Project Number
-
Thanks
-
References
- Baharak A, Reza K, Shahriar D, Omid A, Daruoosh V, Nasrin A, 2012: Metastatic apocrine sweat gland adenocarcinoma in a terrier dog.Asian Pacific Journal of Tropical Biomedicine, 2(8), 670-672.
- Chamberlain RS, Huber K, White JC, Travaglino-Parda R, 1999: Apocrine gland carcinoma of axilla: review of the literature and recommendation for treatment. American Journal of Clinical Oncology, 22 (2), 131-135.
- Ginn PE,Mansett JEKL, Rakich PM (1993).Skin and appendages. In: Jubb, Kennedy and Palmer’s Pathology of Domestic Animals, Maxie MG (ed), 757-758, Academic Press, San Diego.
- Girgin A, Alabay B,Liman N, Özfiliz N, Gülmez N, Özcan Z, Yörük M, Erdost H, Aslan Ş, Ergün L, Zık B (2008).Örtü Sistemi. In: Veteriner Özel Histoloji, Özer A (ed),117-133, Nobel Basımevi,Ankara.
- Goldschmidt M, Hendrick M (2002). Tumors of Skin and Soft Tissues. In: Tumors in Domestic Animals, Meuten DJ (Ed), 45-117,Iowa State Press, Ames, Iowa.
- Haziroğlu R, Haligur M, Keles H, 2014: Histopathological and immunohistochemical studies of apocrine sweat gland adenocarcinomas in cats.Veterinary and Comparative Oncology, 12 (1), 85-90.
- Kalaher K, Anderson W, Scott D, 1990: Neoplasms of the apocrine sweat glands in 44 dogs and 10 cats.The Veterinary Record, 127 (16), 400-403.
- Khodakaram-Tafti A, Khub A, Shirian S, 2012: Pathology and immunohistochemical characteristics of apocrine sweat gland adenocarcinoma in a dog. Comparative Clinical Pathology, 21 (2), 237-239.
- Matthias N, Lockworth CR, Zhang F, Lee MH, Yeung SCJ, Tsai KY, Hamir AN, 2012:Multiple cystic sweat gland tumors in transgenic mice.Comparative Medicine, 62 (1), 27-30.
- Miller M, Nelson S, Turk J, Pace L, Brown T, Shaw D, Fischer J, Gosser H, 1991: Cutaneous neoplasia in 340 cats.Veterinary Pathology, 28 (5), 389-395.
- Nibe K, Uchida K, Itoh T, Tateyama S, 2005: A case of canine apocrine sweat gland adenoma, clear cell variant.Veterinary Pathology, 42 (2), 215-218.
- Sato K, Leidal R, Sato F, 1987: Morphology and development of an apoeccrine sweat gland in human axillae. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 252 (1), 167-180.
- Tessele B, Rissi DR, Langohr IM, Vielmo A, Barros CS, 2015: Mixed apocrine adenocarcinoma of the tail in a cow. Brazilian Journal of Veterinary Pathology, 8 (2),72-75.
Abstract
Bu raporda 13 yaşlı, erkek, tekir ırkı bir kedide apokrin ter bezi adenokarsinomunun klinik, radyolojik, makroskobik ve histopatolojik bulguları sunulmuştur. Klinik muayenede, abdomen ve tüber koksa bölgesinde yumuşak doku kitleleri tespit edildi. Radyolojik muayenesinde yumuşak doku kontrastlı deri altı kitle tespit edildi ve genel anestezi altında cerrahi operasyonla kitleler alındı. Kitlelerin boyutları caudal abdomende yaklaşık 2x2x3 cm, tüber koksa bölgesinde yaklaşık 1x1x2 cm ebatlarında belirlendi. Kitlenin kesit yüzü beyazımsı-sarı renkli görünümdeydi. Kitleler, %10’luk formaldehit solüsyonunda tespit edildikten sonra, rutin histopatoloji prosedürü uygulandı. Histolopatolojik incelemede apokrin ter bezlerinin, kistik yapıda olduğu ve kistin ortasından lümene doğru uzantıların olduğu tespit edildi. Apokrin ter bezi adenokarsinomunun histolopatolojik olarak papiller-kistik tipte olduğu belirlendi. Ter bezinin lümene bakan epitel hücrelerinde anizonükleozis, anizositozis ve polimorfik hücreler ile dev nukleuslu anaplastik hücreler görüldü.
Keywords
Project Number
-
References
- Baharak A, Reza K, Shahriar D, Omid A, Daruoosh V, Nasrin A, 2012: Metastatic apocrine sweat gland adenocarcinoma in a terrier dog.Asian Pacific Journal of Tropical Biomedicine, 2(8), 670-672.
- Chamberlain RS, Huber K, White JC, Travaglino-Parda R, 1999: Apocrine gland carcinoma of axilla: review of the literature and recommendation for treatment. American Journal of Clinical Oncology, 22 (2), 131-135.
- Ginn PE,Mansett JEKL, Rakich PM (1993).Skin and appendages. In: Jubb, Kennedy and Palmer’s Pathology of Domestic Animals, Maxie MG (ed), 757-758, Academic Press, San Diego.
- Girgin A, Alabay B,Liman N, Özfiliz N, Gülmez N, Özcan Z, Yörük M, Erdost H, Aslan Ş, Ergün L, Zık B (2008).Örtü Sistemi. In: Veteriner Özel Histoloji, Özer A (ed),117-133, Nobel Basımevi,Ankara.
- Goldschmidt M, Hendrick M (2002). Tumors of Skin and Soft Tissues. In: Tumors in Domestic Animals, Meuten DJ (Ed), 45-117,Iowa State Press, Ames, Iowa.
- Haziroğlu R, Haligur M, Keles H, 2014: Histopathological and immunohistochemical studies of apocrine sweat gland adenocarcinomas in cats.Veterinary and Comparative Oncology, 12 (1), 85-90.
- Kalaher K, Anderson W, Scott D, 1990: Neoplasms of the apocrine sweat glands in 44 dogs and 10 cats.The Veterinary Record, 127 (16), 400-403.
- Khodakaram-Tafti A, Khub A, Shirian S, 2012: Pathology and immunohistochemical characteristics of apocrine sweat gland adenocarcinoma in a dog. Comparative Clinical Pathology, 21 (2), 237-239.
- Matthias N, Lockworth CR, Zhang F, Lee MH, Yeung SCJ, Tsai KY, Hamir AN, 2012:Multiple cystic sweat gland tumors in transgenic mice.Comparative Medicine, 62 (1), 27-30.
- Miller M, Nelson S, Turk J, Pace L, Brown T, Shaw D, Fischer J, Gosser H, 1991: Cutaneous neoplasia in 340 cats.Veterinary Pathology, 28 (5), 389-395.
- Nibe K, Uchida K, Itoh T, Tateyama S, 2005: A case of canine apocrine sweat gland adenoma, clear cell variant.Veterinary Pathology, 42 (2), 215-218.
- Sato K, Leidal R, Sato F, 1987: Morphology and development of an apoeccrine sweat gland in human axillae. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 252 (1), 167-180.
- Tessele B, Rissi DR, Langohr IM, Vielmo A, Barros CS, 2015: Mixed apocrine adenocarcinoma of the tail in a cow. Brazilian Journal of Veterinary Pathology, 8 (2),72-75.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Case Report |
| Authors | |
| Project Number | - |
| Publication Date | June 22, 2021 |
| Submission Date | September 22, 2020 |
| Acceptance Date | January 11, 2021 |
| Published in Issue | Year 2021 Volume: 10 Issue: 1 |
