Journal of The Faculty of Veterinary Medicine Istanbul University

Abstract

Özet

Bu yazıda intermittens karekterli ateş, halsizlik, depresyon, kıllarda matlık, skrotumda kızarık­lık ve kanlı burun akıntısı şikayetleriyle kliniğe getirilen 3.5 yaşında erkek Bull Terrier ırkı bir köpekte Ehrlichiosis olgusu incelendi. Klinik muayenede hepalomegali, splenomegali. lenfadenopatİ ve mukozalarda solgunluk saptandı. Trombositopeni (40 mm³/10³) ve anemiyi içeren hematolojik anormalliklere ilave olarak, idrar kültüründe 3 hemolitİk streptokok kolonilerinin (10⁵) ürediği, biyokimyasal kan muayenesinde serum to­tal protein (9.4 g/dl), globulin (6.3 g/dl), üre (181 mg/dl), kreatinin (4.7 mg/dl) düzeylerinin arttığı ve albumin (3.1 g/dl) düzeyinin düştüğü saptandı, indirect fluorescent antibody (İFA) testi kullanılarak yapılan sero-îojik muayene de 1/40 oranında Ehrlichia canis antikor titrasyonu saptandı. Klinik, hematolojik, biyokimyasal, mikrobiyoloijk laboratuar bulguları göz önüne alındığında, olguya kronik Ehrlichiosis tanısı konuldu. Doxycyclin (20 mg/kg) ve Sulfanamid-trimethoprim (30 mg/kg) kombinasyonu üç hafla süreyle günde iki defa oral yolla tedavi için kullanıldı. Ülkemizde Ehrlichiosis'in ilk kez saptandığı köpek bu ilaçlarla tamamen iyileştirildi.

Anahtar Kelimeler: Köpek, Ehrlichiosis, trombositopeni, tedavi, Rhipİcephaius sanguineus

CASE OF EHRLICHIOSIS IN A DOG

Summary

In this paper, it was described 3,5 years old, male, Bull Terrier breed a dog which was came to our clinic with anamnesis such as intermittent fever, weakness, depression, become dull in hairs, hype­remia in scrotum and nasal discharges with blood. It was determined hepatomegaly, splenomegaly, lymphadenopathy and paleness of mucous membranes in clinical examination. In addition to hematological abnormali­ties including trombocytopenia (40 mm/10³) and anemia, İt was determined that β hemolytic streptococci colonies (10³) reproduced in urine culture, serum total protein (9.4 g/dl). globulin (6.3 g/dl), urea (181 mg/dl), kreatinin (4.7mg/dl) levels increased and aibumin (3.1 g/dl) level decreased in blood examination. Ehrlichia canis antibody titration 1/40 in ratio was found by used indirect fluorescent antibody (IFA) test. When clinical and laboratory sings such as hematological, biochemical and microbiological were considered, the case was diagnosed of chronic Ehrlichiosis, Doxycilyn (20 mg/kg) and sulfonamide-trimethoprim (30 mg/kg) were used twice a day during three weeks as oral for treatment. The dog that Ehrlichiosis was firstly determined in our country was entirely treated with drugs.

Key Words: Dog, Ehrlichiosis, trombocytopenia, treatment, Rhipicepftalus sanguineus