Case Report
BibTex RIS Cite

Year 2023, Volume: 3 Issue: 1, 1 - 5, 20.06.2023

Yakup Kocaman

Abstract

References

  • 1. Bedford PG, Longstaffe JA. 1979. Corneal pannus (chronic superficial keratitis) in German shepherd dog. J Small Anim Pract, 20(1), 41-56. doi: 10.1111/j.1748- 5827.1979.tb07019.x.
  • 2. Slatter DH, Lavach JD, Severin GA, Young S. 1977. Uberreiter’s syndrome (chronic superficial keratitis) in dogs in the Rocky Mountain area--a study of 463 cases. J Small Anim Pract, 18(12), 757-72. doi: 10.1111/j.1748-5827.1977. tb05852.x
  • 3. Grahn, B. H., & Peiffer, R. L. (2013). Veterinary ophthalmic pathology. Veterinary ophthalmology, 1(490), 67-69.
  • 4. Blythe, L. L., Gannon, J. R., Craig, A. M., & Fegan, D. P. (2007). Care of the racing & retired greyhound. Dostupné z: http://www. dogracing. cz/upload/greyhound_krev. pdf.
  • 5. Campbell, L. H., Okuda, H. K., Lipton, D. E., & Reed, C. (1975). Chronic superficial keratitis in dogs: detection of cellular hypersensitivity. American journal of veterinary research, 36(5), 669-671.
  • 6. Cheng S, Wigney D, Haase B, Wade CM. 2016. Inheritance of chronic superficial keratitis in the Australian Greyhounds. Anim Genet, 47(5), 629. doi: 10.1111/age.12446.
  • 7. Barrientos, L. S., Zapata, G., Crespi, J. A., Posik, D. M., Díaz, S., Peral-García, P., & Giovambattista, G. (2013). A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1. Veterinary immunology and immunopathology, 156(3- 4), 205-210.
  • 8. Jokinen, P., Rusanen, E. M., Kennedy, L. J., & Lohi, H. (2011). MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. Veterinary immunology and immunopathology, 140(1-2), 37-41.
  • 9. Stades, F. C., Wyman, M., Boevé, M. H., Neumann, W., & Spiess, B. (2007). Ophtalmology foqr the Veterinary Practitioner.
  • 10. Maggs, D. J. (2013). Cornea and sclera In: Maggs DJ, Miller PE, Ofri R, eds. Slatters Fundamentals of Veterinary Ophthalmology, 184-219.
  • 11. Balicki, I. (2012). Clinical study on the application of tacrolimus and DMSO in the treatment of chronic superficial keratitis in dogs. Polish journal of veterinary sciences.
  • 12. GELATT, K. N. (2002). Diseases and surgery of the canine cornea and sclera. Animal Eye Research, 21(3-4), 105-113.
  • 13. Williams, D. L., Hoey, A. J., & Smitherman, P. (1995). Comparison of topical cyclosporin and dexamethasone for the treatment of chronic superficial keratitis in dogs. Veterinary Record-English Edition, 137(25), 635-639.
  • 14. Barachetti L, Rampazzo A, Mortellaro CM, Scevola S, Gilger BC. 2015. Use of episcleral cyclosporine implants in dogs with keratoconjunctivitis sicca: pilot study. Vet Opthalmol, 18(3), 234-41. doi:10.1111/vop.12173.
  • 15. Lallemand F, Schmitta M, Bourges JL, Gurny R, Benita S, Garrigue JS. 2017. Cyclosporine A delivery to the eye: A comprehensive review of academic and industrial efforts. Eur J Pharm Biopharm, 117, 14-28. doi: 10.1016/j. ejpb.2017.03.006.
  • 16. Ergin, I., Sainkaplan, S., & Şenel, O. O. (2021). Clinical assessment of chronic superficial keratitis (Überreiter’s syndrome) in dogs: A retrospective study (2012-2019). VETERINARIA, 70(2), 185-195
  • 17. Huang, T., Wang, Y., Liu, Z., Wang, T., & Chen, J. (2007). Investigation of tear film change after recovery from acute conjunctivitis. Cornea, 26(7), 778-781.
  • 18. Drahovska Z, Balicki I, Trbolova A, Mihalova M, Holickova M. 2014. A retrospective study of the occurence of chronic superficial keratitis in 308 German Shepherd dogs: 1999- 2010. Polish J Vet Sci, 17(3), 543-6. doi: 10.2478/pjvs-2014- 0082.
  • 19. Turner SM. 2008. Chronic superficial keratitis. In Turner SM (Ed), Small Animal Opthalmology (2nd ed., pp. 183-7). Philadelphia, USA: Saunders Elsevier., Barrientos LS, Zapata G, Crespi JA, Posik DM, Diaz S, It V, et al. 2013. A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLADQA1. Vet Immunol Immunopathol, 156, 205-10. doi: 10.1016/j.vetimm.2013.10.009
  • 20. Denk N, Fritsche J, Reese S. 2011. The effect of UV-blocking contact lenses as a therapy for canine chronic superficial keratitis. Vet Opthalmol, 14(3), 186-194. doi: 10.1111/j.1463- 5224.2010.00863.x.

A Case of Chronic Superficial Keratitis in a German Shepherd Dog

Year 2023, Volume: 3 Issue: 1, 1 - 5, 20.06.2023

Yakup Kocaman

Abstract

Chronic superficial keratitis, known as Paunnus and Uberreitter's syndrome, is a progressive autoimmune eye disease, especially in German shepherd dogs, Belgian shepherd dogs and greyhound breed dogs. Although the cause of the disease is not exactly known, age, racial predisposition, ultraviolet radiation, high altitude and other eye diseases trigger the formation of pannus. Ocular defects in affected animals are non-infectious and respond to treatment based on topical steroids and immunosuppressive drugs. There is no complete cure for the disease. The aim of the treatment is to significantly improve the quality of life of patients by achieving a significant reduction in symptoms. A patient with bilateral conjunctivitis in the eye and vascularization, pigmentation, epithelial perforation in the cornea in a seven-year-old male German shepherd dog was brought to our hospital for treatment. The treatment was continued regularly for five weeks and a significant decrease in corneal symptoms was observed.

Keywords

Autoimmune Keratitis Pannus Pigmentatio

References

  • 1. Bedford PG, Longstaffe JA. 1979. Corneal pannus (chronic superficial keratitis) in German shepherd dog. J Small Anim Pract, 20(1), 41-56. doi: 10.1111/j.1748- 5827.1979.tb07019.x.
  • 2. Slatter DH, Lavach JD, Severin GA, Young S. 1977. Uberreiter’s syndrome (chronic superficial keratitis) in dogs in the Rocky Mountain area--a study of 463 cases. J Small Anim Pract, 18(12), 757-72. doi: 10.1111/j.1748-5827.1977. tb05852.x
  • 3. Grahn, B. H., & Peiffer, R. L. (2013). Veterinary ophthalmic pathology. Veterinary ophthalmology, 1(490), 67-69.
  • 4. Blythe, L. L., Gannon, J. R., Craig, A. M., & Fegan, D. P. (2007). Care of the racing & retired greyhound. Dostupné z: http://www. dogracing. cz/upload/greyhound_krev. pdf.
  • 5. Campbell, L. H., Okuda, H. K., Lipton, D. E., & Reed, C. (1975). Chronic superficial keratitis in dogs: detection of cellular hypersensitivity. American journal of veterinary research, 36(5), 669-671.
  • 6. Cheng S, Wigney D, Haase B, Wade CM. 2016. Inheritance of chronic superficial keratitis in the Australian Greyhounds. Anim Genet, 47(5), 629. doi: 10.1111/age.12446.
  • 7. Barrientos, L. S., Zapata, G., Crespi, J. A., Posik, D. M., Díaz, S., Peral-García, P., & Giovambattista, G. (2013). A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1. Veterinary immunology and immunopathology, 156(3- 4), 205-210.
  • 8. Jokinen, P., Rusanen, E. M., Kennedy, L. J., & Lohi, H. (2011). MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. Veterinary immunology and immunopathology, 140(1-2), 37-41.
  • 9. Stades, F. C., Wyman, M., Boevé, M. H., Neumann, W., & Spiess, B. (2007). Ophtalmology foqr the Veterinary Practitioner.
  • 10. Maggs, D. J. (2013). Cornea and sclera In: Maggs DJ, Miller PE, Ofri R, eds. Slatters Fundamentals of Veterinary Ophthalmology, 184-219.
  • 11. Balicki, I. (2012). Clinical study on the application of tacrolimus and DMSO in the treatment of chronic superficial keratitis in dogs. Polish journal of veterinary sciences.
  • 12. GELATT, K. N. (2002). Diseases and surgery of the canine cornea and sclera. Animal Eye Research, 21(3-4), 105-113.
  • 13. Williams, D. L., Hoey, A. J., & Smitherman, P. (1995). Comparison of topical cyclosporin and dexamethasone for the treatment of chronic superficial keratitis in dogs. Veterinary Record-English Edition, 137(25), 635-639.
  • 14. Barachetti L, Rampazzo A, Mortellaro CM, Scevola S, Gilger BC. 2015. Use of episcleral cyclosporine implants in dogs with keratoconjunctivitis sicca: pilot study. Vet Opthalmol, 18(3), 234-41. doi:10.1111/vop.12173.
  • 15. Lallemand F, Schmitta M, Bourges JL, Gurny R, Benita S, Garrigue JS. 2017. Cyclosporine A delivery to the eye: A comprehensive review of academic and industrial efforts. Eur J Pharm Biopharm, 117, 14-28. doi: 10.1016/j. ejpb.2017.03.006.
  • 16. Ergin, I., Sainkaplan, S., & Şenel, O. O. (2021). Clinical assessment of chronic superficial keratitis (Überreiter’s syndrome) in dogs: A retrospective study (2012-2019). VETERINARIA, 70(2), 185-195
  • 17. Huang, T., Wang, Y., Liu, Z., Wang, T., & Chen, J. (2007). Investigation of tear film change after recovery from acute conjunctivitis. Cornea, 26(7), 778-781.
  • 18. Drahovska Z, Balicki I, Trbolova A, Mihalova M, Holickova M. 2014. A retrospective study of the occurence of chronic superficial keratitis in 308 German Shepherd dogs: 1999- 2010. Polish J Vet Sci, 17(3), 543-6. doi: 10.2478/pjvs-2014- 0082.
  • 19. Turner SM. 2008. Chronic superficial keratitis. In Turner SM (Ed), Small Animal Opthalmology (2nd ed., pp. 183-7). Philadelphia, USA: Saunders Elsevier., Barrientos LS, Zapata G, Crespi JA, Posik DM, Diaz S, It V, et al. 2013. A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLADQA1. Vet Immunol Immunopathol, 156, 205-10. doi: 10.1016/j.vetimm.2013.10.009
  • 20. Denk N, Fritsche J, Reese S. 2011. The effect of UV-blocking contact lenses as a therapy for canine chronic superficial keratitis. Vet Opthalmol, 14(3), 186-194. doi: 10.1111/j.1463- 5224.2010.00863.x.
There are 20 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section Case Reports
Authors

Yakup Kocaman

Publication Date June 20, 2023
Published in Issue Year 2023 Volume: 3 Issue: 1

Cite

AMA Kocaman Y. A Case of Chronic Superficial Keratitis in a German Shepherd Dog. J Vet C Rep. June 2023;3(1):1-5.

Content of this journal is licensed under a Creative Commons Attribution NonCommercial 4.0 International License

30834