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BİR KEDİDE EKSTRAMEDÜLLER PLAZMASİTOM (EMP) OLGUSU

Year 2016, Volume: 1 Issue: 1, 83 - 86, 23.06.2016
https://doi.org/10.24880/maeuvfd.260793

Abstract

Özet: Bu çalışmanın materyalini 10 yaşlı, melez ırk, erkek bir kediden dilaltından alınan tümöral kitle oluşturdu. Alt çenede molar dişleri hizasında gingival mukozaya yerleşen kitle dilin ventral yüzüne doğru yayılım gösteriyordu.  Üst yüzeyi mukoza ile kaplı kitle 1x1x1.5 cm boyutlarında, oval şekilli ve üst yüzü pürüzlü görünümdeydi. Kesit yüzü pembe renkli olan kitle yer yer kanamalı sahalar içeriyordu.  Kitlenin histopatolojik yoklamasında submukozada, çok sayıda,  iyi diferensiye olmuş, çekirdekleri hücrenin bir ucuna yerleşmiş, belirgin ve bazofilik sitoplazmalı tipik plazma hücrelerinden oluşan bir kitle gözlendi. Kitle iyi damarlaşmış ve kapsülsüz bir yapıya sahipti. Bazı alanlarda mukozanın epitel tabakasının ülsere olduğu ve bu bölgelerde nötrofil lökosit infiltrasyonları bulunduğu gözlendi. Mikroskobik bulgulara göre kitleye ektramedüller plazmositom (EMP) tanısı konuldu. Ektramedüller plazmositomların kedilerde ağız içinde yerleşiminin ender görülmesi sebebiyle rapor edilmesi uygun bulundu.

References

  • Kaynaklar
  • Fry MM, McGavin MD. Plasma cell neoplasia. In: McGavin MD, Zachary JF, editors. Pathologic Basis of Veterinary Diseases, 4th. Ed. China; Mosby Elsevier. p.802-803, 2007.
  • Majzoub M, Breuer W, Platz SJ, Linke RP, Hermanns W. Histopathologic and immunophenotypic characterization of extramedullary plasmacytomas in nine cats. Vet Pathol. 2003; 40: 249-253.
  • Wright, ZM, Rogers KS, Mansell J. Survival data for canine oral extramedullary plasmacytomas: a retrospective analysis. JAVMA 2008; 44: 75–81.
  • Brown CC, Baker DC, Baker IK. Plasmacytomas. In: Maxie MG, editor. Jubb, Kennedy and Palmer’s Pathology of Domestic Animals, 5th ed. p. 31. Philadelphia: Saunders Elsevier; 2007.
  • Meuten DJ. Tumors in Domestic Animals, Fourth Edition, Iowa State Press, p. 113, 2002.
  • Clark GN, Berg J, Engler SJ, Bronson RT. Extramedullary plasmacytomas in dogs: results of surgical excision in 131 cases. J Am Anim Hosp Assoc. 1992; 28: 105–111.
  • Jackson MW, Helfand SC, Smedes SL, Bradley GA, Schultz RD. Primary IgG secreting plasma cell tumor in the gastrointestinal tract of a dog. JAVMA 1994; 204: 404–406.
  • Rakich PM, Latimer KS, Weiss R, Steffens WL. Mucocutaneous plasmacytomas in dogs: 75 cases (1980–1987). JAVMA 1989; 194: 803–811.
  • Goldschmidt MH, Hendrick MJ. Tumors of the skin and soft tissues. In: MeutenDJ, ed. Tumors in Domestic Animals. 2nd ed. Ames, Ia: Iowa State University Press; 2002:113–114.
  • Baer KE, Patnaik AK, Gilbertson SR, Hurvitz AI. Cutaneous plasmacytomas in dogs: a morphologic and immunohistochemical study. Vet Pathol. 1989; 26: 216–221.
  • Baker R, Lumsden JH. The skin. In: Baker R, Lumsden JH, eds. Color Atlas of Cytology of the Dog and Cat. St. Louis, Mo: CV Mosby; 2000: 39–70.
Year 2016, Volume: 1 Issue: 1, 83 - 86, 23.06.2016
https://doi.org/10.24880/maeuvfd.260793

Abstract

References

  • Kaynaklar
  • Fry MM, McGavin MD. Plasma cell neoplasia. In: McGavin MD, Zachary JF, editors. Pathologic Basis of Veterinary Diseases, 4th. Ed. China; Mosby Elsevier. p.802-803, 2007.
  • Majzoub M, Breuer W, Platz SJ, Linke RP, Hermanns W. Histopathologic and immunophenotypic characterization of extramedullary plasmacytomas in nine cats. Vet Pathol. 2003; 40: 249-253.
  • Wright, ZM, Rogers KS, Mansell J. Survival data for canine oral extramedullary plasmacytomas: a retrospective analysis. JAVMA 2008; 44: 75–81.
  • Brown CC, Baker DC, Baker IK. Plasmacytomas. In: Maxie MG, editor. Jubb, Kennedy and Palmer’s Pathology of Domestic Animals, 5th ed. p. 31. Philadelphia: Saunders Elsevier; 2007.
  • Meuten DJ. Tumors in Domestic Animals, Fourth Edition, Iowa State Press, p. 113, 2002.
  • Clark GN, Berg J, Engler SJ, Bronson RT. Extramedullary plasmacytomas in dogs: results of surgical excision in 131 cases. J Am Anim Hosp Assoc. 1992; 28: 105–111.
  • Jackson MW, Helfand SC, Smedes SL, Bradley GA, Schultz RD. Primary IgG secreting plasma cell tumor in the gastrointestinal tract of a dog. JAVMA 1994; 204: 404–406.
  • Rakich PM, Latimer KS, Weiss R, Steffens WL. Mucocutaneous plasmacytomas in dogs: 75 cases (1980–1987). JAVMA 1989; 194: 803–811.
  • Goldschmidt MH, Hendrick MJ. Tumors of the skin and soft tissues. In: MeutenDJ, ed. Tumors in Domestic Animals. 2nd ed. Ames, Ia: Iowa State University Press; 2002:113–114.
  • Baer KE, Patnaik AK, Gilbertson SR, Hurvitz AI. Cutaneous plasmacytomas in dogs: a morphologic and immunohistochemical study. Vet Pathol. 1989; 26: 216–221.
  • Baker R, Lumsden JH. The skin. In: Baker R, Lumsden JH, eds. Color Atlas of Cytology of the Dog and Cat. St. Louis, Mo: CV Mosby; 2000: 39–70.
There are 12 citations in total.

Details

Journal Section Case Reports
Authors

Nilay Serpin This is me

Ozlem Özmen

Birol Can Eren This is me

Publication Date June 23, 2016
Submission Date March 29, 2016
Published in Issue Year 2016 Volume: 1 Issue: 1

Cite

APA Serpin, N., Özmen, O., & Eren, B. C. (2016). BİR KEDİDE EKSTRAMEDÜLLER PLAZMASİTOM (EMP) OLGUSU. Veterinary Journal of Mehmet Akif Ersoy University, 1(1), 83-86. https://doi.org/10.24880/maeuvfd.260793