Abstract
Probiotics are live microorganisms that have desirable effects on human health when taken in adequate amounts. In recent years, it has been revealed that there is a relationship between obesity and probiotics, which is one of the important health problems. The imbalance between energy intake and expenditure, unhealthy lifestyle and genetic factors play a role in obesity. Modulation of gut microbiota with components including probiotics and functional food products has been suggested as a novel approach to treat or prevent obesity. Probiotics develop a mechanism against obesity by improving lipid and glucose metabolism, regulating intestinal microbiota composition, and suppressing metabolic inflammation. With the consumption of probiotic food, the diversity in the intestinal microbiota increases and the metabolic functions of these microbial cells and the risk of obesity are reduced. In this review, the relationship between the presence and diversity of probiotic microorganisms in the intestinal microbiota and obesity as a result of probiotic food consumption is emphasized.
Keywords
References
- Abenavoli L., Scarpellini E., Colica C., Boccuto L., Salehi B., Sharifi-Rad J., Aiello V., Romano B., Lorenzo A., Izzo AA., Capasso R. Gut microbiota and obesity: A role for probiotics. Nutrients 2019; 11(11): 2690.
- Aguilera XEL., Manzano A., Pirela D., Bermúdez V. Probiotics and gut microbiota in obesity: Myths and realities of a new health revolution. Journal of Personalized Medicine 2022; 12(8): 1282.
- Alagözlü H. Barsak mikrobiyotası ve obezite. Turkiye Klinikleri J Gastroenterohepatol-Special Topics 2016; 9(2): 28-33.
- Arslan N. Obezite ile barsak mikrobiyotası ilişkisi ve obezitede prebiyotikler ve probiyotiklerin kullanımı. Beslenme ve Diyet Dergisi 2014; 42(2): 148-153.
- Ayas I. Obezite ile mücadelede obezite vergilerinin algılanan etkinliği. Sakarya Üniversitesi, Sosyal Bilimler Enstitüsü, Doktora Tezi, Sayfa no:240, Sakarya, Türkiye, 2016.
- Barathikannan K., Chelliah R., Rubab M., Daliri EBM., Elahi F., Kim DH., Agaistian P., Oh SY., Oh DH. Gut microbiome modulation based on probiotic application for anti-obesity: A review on efficacy and validation. Microorganisms 2019; 7(10): 456.
- Barengolts E., Smith ED., Reutrakul S., Tonucci L., Anothaisintawee T. The effect of probiotic yogurt on glycemic control in type 2 diabetes or obesity: A meta-analysis of nine randomized controlled trials. Nutrients 2019; 11(3): 671.
- Cerdó T., García-Santos JA., G. Bermúdez M., Campoy, C. The role of probiotics and prebiotics in the prevention and treatment of obesity. Nutrients 2019; 11(3): 635.
- Çatak J., Yıldırım E., Memiş N. Obezite ve mikrobiyota etkileşimlerine genel bakış. Avrupa Bilim ve Teknoloji Dergisi 2021; 31: 275-291.
- Ejtahed HS., Angoorani P., Soroush A. R., Atlasi R., Hasani-Ranjbar S., Mortazavian AM., Larijani B. Probiotics supplementation for the obesity management; A systematic review of animal studies and clinical trials. Journal of Functional Foods 2019; 52: 228-242.
- Erkul C., Alphan ME. Bağırsak mikrobiyotası ve obezite ilişkisi. İzmir Kâtip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi 2020; 5(1): 35-39.
- Green M., Arora K., Prakash S. Microbial medicine: Prebiotic and probiotic functional foods to target obesity and metabolic syndrome. International Journal of Molecular Sciences 2020; 21(8): 2890.
- Kim DH., Kim H., Jeong D., Kang IB., Chon JW., Kim HS. Kefir alleviates obesity and hepatic steatosis in high-fat diet-fed mice by modulation of gut microbiota and mycobiota: Targeted and untargeted community analysis with correlation of biomarkers. The Journal of Nutritional Biochemistry, 2017; 44: 35-43.
- Kobyliak N., Conte C., Cammarota G., Haley AP., Styriak I., Gaspar L., Fusek G., Rodrigo L., Kruzliak P. Probiotics in prevention and treatment of obesity: A critical view. Nutrition & Metabolism 2016; 13(1): 1-13.
- Lau E., Neves JS., Ferreira-Magalhães M., Carvalho D., Freitas P. Probiotic ingestion, obesity, and metabolic-related disorders: Results from NHANES, 1999–2014. Nutrients 2019; 11(7): 1482.
- Ley RE., Bäckhed F., Turnbaugh P., Lozupone CA., Knight RD., Gordon JI. Obesity alters gut microbial ecology. Proc. Natl. Acad. Sci. 2005; 102, 11070-11075.
- Mazloom K., Siddiqi I., Covasa M. Probiotics: How effective are they in the fight against obesity?. Nutrients 2019; 11(2): 258.
Abstract
Probiyotikler yeterli miktarda alındıklarında insan sağlığı üzerinde yararlı etkileri olan canlı mikroorganizmalardır. Son yıllarda önemli sağlık sorunlarından biri olan obezite ve probiyotikler arasında ilişki olduğu ortaya çıkarılmıştır. Obezitede enerji alımı ve harcanması arasındaki dengesizlik, sağlıksız yaşam biçimi ve genetik faktörler rol oynamaktadır. Obeziteyi tedavi etme veya önlemede yeni bir yaklaşım olarak bağırsak mikrobiyotasının probiyotik ve fonksiyonel gıdalar gibi bileşenlerle modülasyonu önerilmiştir. Probiyotikler; lipid ve glikoz metabolizmasını iyileştirerek, bağırsak mikrobiyota kompozisyonunu düzenleyerek ve metabolik inflamasyonu baskılayarak obeziteye karşı bir mekanizma geliştirirler. Probiyotik gıda tüketimi ile birlikte ise; bağırsak mikrobiyotasındaki çeşitlilik artar ve bu mikrobiyel hücrelerin metabolik fonksiyonları ile obezite riski azaltılır. Bu derlemede; probiyotik gıda tüketiminin bir sonucu olarak bağırsak mikrobiyotasındaki probiyotik mikroorganizma varlığı ve çeşitliliğinin obezite ile ilişkisi üzerinde durulmuştur.
References
- Abenavoli L., Scarpellini E., Colica C., Boccuto L., Salehi B., Sharifi-Rad J., Aiello V., Romano B., Lorenzo A., Izzo AA., Capasso R. Gut microbiota and obesity: A role for probiotics. Nutrients 2019; 11(11): 2690.
- Aguilera XEL., Manzano A., Pirela D., Bermúdez V. Probiotics and gut microbiota in obesity: Myths and realities of a new health revolution. Journal of Personalized Medicine 2022; 12(8): 1282.
- Alagözlü H. Barsak mikrobiyotası ve obezite. Turkiye Klinikleri J Gastroenterohepatol-Special Topics 2016; 9(2): 28-33.
- Arslan N. Obezite ile barsak mikrobiyotası ilişkisi ve obezitede prebiyotikler ve probiyotiklerin kullanımı. Beslenme ve Diyet Dergisi 2014; 42(2): 148-153.
- Ayas I. Obezite ile mücadelede obezite vergilerinin algılanan etkinliği. Sakarya Üniversitesi, Sosyal Bilimler Enstitüsü, Doktora Tezi, Sayfa no:240, Sakarya, Türkiye, 2016.
- Barathikannan K., Chelliah R., Rubab M., Daliri EBM., Elahi F., Kim DH., Agaistian P., Oh SY., Oh DH. Gut microbiome modulation based on probiotic application for anti-obesity: A review on efficacy and validation. Microorganisms 2019; 7(10): 456.
- Barengolts E., Smith ED., Reutrakul S., Tonucci L., Anothaisintawee T. The effect of probiotic yogurt on glycemic control in type 2 diabetes or obesity: A meta-analysis of nine randomized controlled trials. Nutrients 2019; 11(3): 671.
- Cerdó T., García-Santos JA., G. Bermúdez M., Campoy, C. The role of probiotics and prebiotics in the prevention and treatment of obesity. Nutrients 2019; 11(3): 635.
- Çatak J., Yıldırım E., Memiş N. Obezite ve mikrobiyota etkileşimlerine genel bakış. Avrupa Bilim ve Teknoloji Dergisi 2021; 31: 275-291.
- Ejtahed HS., Angoorani P., Soroush A. R., Atlasi R., Hasani-Ranjbar S., Mortazavian AM., Larijani B. Probiotics supplementation for the obesity management; A systematic review of animal studies and clinical trials. Journal of Functional Foods 2019; 52: 228-242.
- Erkul C., Alphan ME. Bağırsak mikrobiyotası ve obezite ilişkisi. İzmir Kâtip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi 2020; 5(1): 35-39.
- Green M., Arora K., Prakash S. Microbial medicine: Prebiotic and probiotic functional foods to target obesity and metabolic syndrome. International Journal of Molecular Sciences 2020; 21(8): 2890.
- Kim DH., Kim H., Jeong D., Kang IB., Chon JW., Kim HS. Kefir alleviates obesity and hepatic steatosis in high-fat diet-fed mice by modulation of gut microbiota and mycobiota: Targeted and untargeted community analysis with correlation of biomarkers. The Journal of Nutritional Biochemistry, 2017; 44: 35-43.
- Kobyliak N., Conte C., Cammarota G., Haley AP., Styriak I., Gaspar L., Fusek G., Rodrigo L., Kruzliak P. Probiotics in prevention and treatment of obesity: A critical view. Nutrition & Metabolism 2016; 13(1): 1-13.
- Lau E., Neves JS., Ferreira-Magalhães M., Carvalho D., Freitas P. Probiotic ingestion, obesity, and metabolic-related disorders: Results from NHANES, 1999–2014. Nutrients 2019; 11(7): 1482.
- Ley RE., Bäckhed F., Turnbaugh P., Lozupone CA., Knight RD., Gordon JI. Obesity alters gut microbial ecology. Proc. Natl. Acad. Sci. 2005; 102, 11070-11075.
- Mazloom K., Siddiqi I., Covasa M. Probiotics: How effective are they in the fight against obesity?. Nutrients 2019; 11(2): 258.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Food Engineering |
| Journal Section | REVIEWS |
| Authors | |
| Publication Date | December 20, 2023 |
| Submission Date | April 28, 2023 |
| Acceptance Date | July 23, 2023 |
| Published in Issue | Year 2023 Volume: 6 Issue: Ek Sayı |
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