Cardiovascular effects of thiopental-sevoflurane compared with thiopental-isoflurane in angora goats undergoing ovariectomy
Abstract
Aim:
The purpose of
this study was to evaluate the effects of inhalation anaesthetics on
cardiovascular functions in 16 healthy female Angora goats undergoing
ovariectomy. Material and Methods: Anaesthesia
was induced with thiopental sodium then maintained with isoflurane or
sevoflurane in oxygen. Cardiovascular parameters were measured before and at 0,
15th, 30th, 60th and 90th minutes after induction of anaesthesia. Recovery variables including time to
extubation, first lift of the head, thoracic recumbency and standing up were
also recorded.
Results: The mean induction dose of thiopental was 18.23 ± 3.87
mg / kg. There were no significant differences between groups for heart rate
(HR), respiration rate (RR), noninvasive blood pressure and body temperature measured
prior to and under anaesthesia. All animals recovered uneventfully in both
groups.
Conclusion: There were no statistical
differences between groups for their cardiovascular parameters and recovery
times although the results of this study showed a rapid recovery time in each
parameter for sevoflurane anaesthesia. On the basis of the results, sevoflurane
and isoflurane are suitable inhalation anaesthetics in goats.
References
- 1. Bleul U, Hollenstein K, Kahn W. Laparascopic ovariectomy in standing cows. Ani Reprod Sci 2005; 90: 193-200.
- 2. Barros FFPC, Teixeira PPM, Silva MAM et. al. Single-port laparoscopic ovariectomy using a pre-tied loop ligature in Santa Ines ewes. Cienc Rural 2015; 45: 2033-38.
- 3. Mutoh T, Nishimura R, Kim HY, Matsunaga S, Sasaki N. Cardiopulmonary effects of sevoflurane, compared with halothane, enflurane and isoflurane in dogs. Am J Vet Res 1997; 58: 885-90.
- 4. Hikasa Y, Hokushin S, Takase K, Ogasawara S. Cardiopulmonary, hematological, serum biochemical and behavioral effects of sevoflurane compared with isoflurane or halothane in spontaneously ventilating goats. Small Rum Res 2002; 43: 167-78.
- 5. Steffey EP, Mama KR, Brosnan JR. Inhalation anesthetics. In: Grim KA. Lamont LA. Tranquilli WJ. Greene SA. Robertson SA (eds). Lumb and Lones’ Veterinary anesthesia and analgesia. 5th ed. USA: Blackwell Publishing; 2007: 297-332.
- 6. Mohamadnia AR, Hughes G, Clarke KW. Maintenance of anaesthesia in sheep with isoflurane, desflurane or sevoflurane. Vet Rec 2008; 163: 210-15.
- 7. Prassinos NN, Galatos AD, Raptopoulos D. A comparison of propofol, thiopental or ketamine as induction agents in goats. Vet Anaesth Analg 2005; 32: 289-96.
- 8. Hall LW, Clarke KW, Trim CM. Anesthesia of sheep, goats and other herbivores. In: Veterinary anaesthesia. 10th ed. China: W. B. Saunders 2001: 341-65.
- 9. Branson KR. Injectable and alternative anesthetic techniques. In: Tranquilli WJ. Thurmon JC. Grim KA (eds). Lumb and Lones’ Veterinary anesthesia and analgesia. 4th ed. USA: Blackwell Publishing 2007: 273-99.
- 10. Riebold TW. Ruminants. In: Grim KA. Lamont LA. Tranquilli WJ. Greene SA. Robertson SA (eds). Lumb and Lones’ Veterinary anesthesia and analgesia. 5th ed. USA: Blackwell Publishing 2007: 912-28.
- 11. Enouri SS, Kerr CL, McDonell WN, Dyson DH. Cardiopulmonary effects of anesthetic induction with thiopental, propofol, or a combination of ketamine hydrocloride and diazepam in dogs sedated with a combination of medetomidine and hydromorphone. Am J Vet Res 2008; 69: 586-95.
- 12. Johnson RA, Striler E, Sawyer DC, Brunson DB. Comparison of isoflurane with sevoflurane for anesthesia induction and recovery in adult dogs. Am J Vet Res 1998; 59: 478-81.
- 13. Kumandaş A, Elma E. Comparison of sevoflurane and isoflurane effects on cardiovascular and respiratory system during spontaneous ventilation in Angora goats. Turkish J Vet An Sci 2015; 39: 501-506.
- 14. Grosenbaugh DA, Muir WW. Cardiorespiratory effects of sevoflurane, isoflurane and halothane anesthesia in horses. Am J Vet Res 1998; 59: 101-106.
- 15. Offinger J, Meyer H, Fischer J, Kastner SBR, Piechotta M, Rehage J. Comparision of isoflurane inhalation anaesthesia, injection anaesthesia and high volume caudal epidural anaesthesia for umbilical surgery in calves; metabolic, endocrine and cardiopulmonary effects. Vet Anaesth Analg 2012; 39: 123-36.
- 16. Brett CM, Teitel DF, Heymann MA, Rudolph AM. The cardiovascular effects of isoflurane in lambs. Anesthesiology 1987; 67: 60-65.
- 17. Hikasa Y, Ohe N, Takase K, Ogasawara S. Cardiopulmonary effects of sevoflurane in cats: comparison with isoflurane, halothane and enflurane. Res Vet Sci 1997; 63: 205-10.
- 18. Gençcelep M, Atasoy N, Taş A. The effects of inhalation anesthetics (halothane and isoflurane) on certain clinical and haematological parameters of sheep. Small Rum Res 2004; 53: 157-60.
- 19. Hikasa Y, Okuyama K, Kakuta T, Takase K, Ogasawara S. Anesthetic potency and cardiopulmonary effects of sevoflurane in goats: comparison with İsoflurane and Halothane. Can J Vet Res 1998; 62: 299-306.
- 20. Matthews NS, Hartsfield SM, Mercer D, Beleau MH, Mackenthun A. Recovery from sevoflurane anesthesia in horses: comparison to isoflurane and effect of postmedication with xylazine. Vet Surg 1998; 27: 480-85.
- 21. Vettorato E, Schöffmann G, Burke JG, Gibson AJN, Clutton ER. Clinical effects of isoflurane and sevoflurane in lambs. Vet Anaesth Analg 2012; 39: 495-502.
- 22. Sellers G, Lin HC, Chamorro MF, Walz PH. Comparison of isoflurane and sevoflurane anesthesia in holstein calves for placement of portal and jugular vein cannulas. Am J An Vet Sci 2013; 8: 1-7.
Ankara keçilerinde ovariektomi operasyonlarında tiopental-sevofluran ile tiopental-isofluran’ın kardiyovasküler sistem üzerine etkilerinin karşılaştırılması
Abstract
Amaç:
Bu çalışmada 16 adet sağlıklı Ankara keçisinin
ovarektomi operasyonlarında kullanılan inhalasyon anesteziklerinin
kardiyovasküler sistem üzerine etkilerinin değerlendirilmesi amaçlanmıştır.
Gereç
ve Yöntemler: Anestezinin
indüksiyonu tiopental sodyum ile yapılmış ve devamında izofluran ve sevofluran
inhalasyon anestezikleri kullanılmıştır. Kardiyovasküler değerler indüksiyondan
önce ve indüksiyon sonrası 0. 15. 30. 60 ve 90. dakikalarda kayıt edilmiştir. Ekstubasyon
ve kafayı ilk kaldırma zamanı, sternal pozisyona gelme ve ayağa kalkma
zamanları uyanma kriterlerini oluşturmuştur.
Bulgular: Tiopental sodyumun ortalama indüksiyon dozu 18.23±3.87 mg/kg
olarak belirlenmiştir. Gruplar arasında, anestezi sırasında ve anesteziden önce nabız
sayısı, solunum sayısı, noninvaziv tansiyon değerleri ve vücut ısısında
farklılık gözlenmemiştir. Tüm hayvanların anesteziden uyanmaları sorunsuz bir
şekilde gerçekleşmiştir.
Sonuç:
Çalışmanın sonucunda kullanılan anesteziklerin
uyanma zamanları ve kardiyovasküler değerler üzerine etkileri arasında
istatistiksel olarak farklılık olmadığı tespit edilmiştir. Sevofluran
anestezisinde tüm uyanma kriterlerinin daha hızlı şekillendiği görülmüştür.
Sonuç olarak her iki anestezik maddeninde keçilerin inhalasyon anestezisinde
kullanımının uygun olduğu kanısına varılmıştır.
Keywords
References
- 1. Bleul U, Hollenstein K, Kahn W. Laparascopic ovariectomy in standing cows. Ani Reprod Sci 2005; 90: 193-200.
- 2. Barros FFPC, Teixeira PPM, Silva MAM et. al. Single-port laparoscopic ovariectomy using a pre-tied loop ligature in Santa Ines ewes. Cienc Rural 2015; 45: 2033-38.
- 3. Mutoh T, Nishimura R, Kim HY, Matsunaga S, Sasaki N. Cardiopulmonary effects of sevoflurane, compared with halothane, enflurane and isoflurane in dogs. Am J Vet Res 1997; 58: 885-90.
- 4. Hikasa Y, Hokushin S, Takase K, Ogasawara S. Cardiopulmonary, hematological, serum biochemical and behavioral effects of sevoflurane compared with isoflurane or halothane in spontaneously ventilating goats. Small Rum Res 2002; 43: 167-78.
- 5. Steffey EP, Mama KR, Brosnan JR. Inhalation anesthetics. In: Grim KA. Lamont LA. Tranquilli WJ. Greene SA. Robertson SA (eds). Lumb and Lones’ Veterinary anesthesia and analgesia. 5th ed. USA: Blackwell Publishing; 2007: 297-332.
- 6. Mohamadnia AR, Hughes G, Clarke KW. Maintenance of anaesthesia in sheep with isoflurane, desflurane or sevoflurane. Vet Rec 2008; 163: 210-15.
- 7. Prassinos NN, Galatos AD, Raptopoulos D. A comparison of propofol, thiopental or ketamine as induction agents in goats. Vet Anaesth Analg 2005; 32: 289-96.
- 8. Hall LW, Clarke KW, Trim CM. Anesthesia of sheep, goats and other herbivores. In: Veterinary anaesthesia. 10th ed. China: W. B. Saunders 2001: 341-65.
- 9. Branson KR. Injectable and alternative anesthetic techniques. In: Tranquilli WJ. Thurmon JC. Grim KA (eds). Lumb and Lones’ Veterinary anesthesia and analgesia. 4th ed. USA: Blackwell Publishing 2007: 273-99.
- 10. Riebold TW. Ruminants. In: Grim KA. Lamont LA. Tranquilli WJ. Greene SA. Robertson SA (eds). Lumb and Lones’ Veterinary anesthesia and analgesia. 5th ed. USA: Blackwell Publishing 2007: 912-28.
- 11. Enouri SS, Kerr CL, McDonell WN, Dyson DH. Cardiopulmonary effects of anesthetic induction with thiopental, propofol, or a combination of ketamine hydrocloride and diazepam in dogs sedated with a combination of medetomidine and hydromorphone. Am J Vet Res 2008; 69: 586-95.
- 12. Johnson RA, Striler E, Sawyer DC, Brunson DB. Comparison of isoflurane with sevoflurane for anesthesia induction and recovery in adult dogs. Am J Vet Res 1998; 59: 478-81.
- 13. Kumandaş A, Elma E. Comparison of sevoflurane and isoflurane effects on cardiovascular and respiratory system during spontaneous ventilation in Angora goats. Turkish J Vet An Sci 2015; 39: 501-506.
- 14. Grosenbaugh DA, Muir WW. Cardiorespiratory effects of sevoflurane, isoflurane and halothane anesthesia in horses. Am J Vet Res 1998; 59: 101-106.
- 15. Offinger J, Meyer H, Fischer J, Kastner SBR, Piechotta M, Rehage J. Comparision of isoflurane inhalation anaesthesia, injection anaesthesia and high volume caudal epidural anaesthesia for umbilical surgery in calves; metabolic, endocrine and cardiopulmonary effects. Vet Anaesth Analg 2012; 39: 123-36.
- 16. Brett CM, Teitel DF, Heymann MA, Rudolph AM. The cardiovascular effects of isoflurane in lambs. Anesthesiology 1987; 67: 60-65.
- 17. Hikasa Y, Ohe N, Takase K, Ogasawara S. Cardiopulmonary effects of sevoflurane in cats: comparison with isoflurane, halothane and enflurane. Res Vet Sci 1997; 63: 205-10.
- 18. Gençcelep M, Atasoy N, Taş A. The effects of inhalation anesthetics (halothane and isoflurane) on certain clinical and haematological parameters of sheep. Small Rum Res 2004; 53: 157-60.
- 19. Hikasa Y, Okuyama K, Kakuta T, Takase K, Ogasawara S. Anesthetic potency and cardiopulmonary effects of sevoflurane in goats: comparison with İsoflurane and Halothane. Can J Vet Res 1998; 62: 299-306.
- 20. Matthews NS, Hartsfield SM, Mercer D, Beleau MH, Mackenthun A. Recovery from sevoflurane anesthesia in horses: comparison to isoflurane and effect of postmedication with xylazine. Vet Surg 1998; 27: 480-85.
- 21. Vettorato E, Schöffmann G, Burke JG, Gibson AJN, Clutton ER. Clinical effects of isoflurane and sevoflurane in lambs. Vet Anaesth Analg 2012; 39: 495-502.
- 22. Sellers G, Lin HC, Chamorro MF, Walz PH. Comparison of isoflurane and sevoflurane anesthesia in holstein calves for placement of portal and jugular vein cannulas. Am J An Vet Sci 2013; 8: 1-7.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Orıgınal Artıcle |
| Authors | |
| Publication Date | March 21, 2019 |
| Published in Issue | Year 2019 Volume: 10 Issue: 1 |
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e-ISSN: 2149-8296
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