Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 1995, , 0 - 0, 01.01.1995
https://doi.org/10.1501/Vetfak_0000000761

Öz

Kaynakça

  • Ankara Üniversitesi – Ankara Üniversitesi Veteriner Fakültesi Dergisi

EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE

Yıl 1995, , 0 - 0, 01.01.1995
https://doi.org/10.1501/Vetfak_0000000761

Öz

The aim of this work is to investigate the effects of nutritional
levels on the secretory functions of the small and large intestine in the mouse.
The study was carried out on male swiss strain adult mice (of approximate
700) weighing 2040 gr. Mice starvedfor 48h refed after 48h starvation allowing themfood ad lib. Mice were also undernourishedfor 4d with 50% (3grlper
mouselper day) of the fed control adult daily food intake. Experimental data
was collectedfrom mice smaIl (midjejunum and proximal ileum) and large intestine (proximal, mid and distal colon).
In mid jejunum and proximal Ueum, funetionaIly distinct differences were
observed by their bioelectric properties [i.e potential difference (PD.), tissue
resistance (R) and basal short-circiuit current (Isc)). These were altered by
changes in nutritional status in the mid jejunum, while those of the proximal ileum remained unchanged. Three functionaIly distinet eolonie segments (proximal, mid and distal) were identified by their bioeleetrie properties (P.D., R and
basal Ise) which varied along the eolon. These properties were altered by
changes in nuıritional status.
When stimulated to secrete the 48h starved mid jejunum and proximal ileum did not exhibit a hypersecretory response to the Ca2+ acting secretory agonists (bethaneehol, 5-HT) and DbeAMP.
In the eolon, after 48h starvation bethaneehol aetivated a higher eleetrogneic seeretion that in the fed controls. The response of the distal colon to
bethaneehol was biphasic. In the proximal and mid colon, in the case of food
deprivation, cye/ic nue/eotide acting secretory agonists (DbcAMP, theophylline)
did not aetivate a hypersecretory response compared to the fed colons. In the
starved proximal colon, atropine potentiared 5-HT-indueed inerease in Ise and
this was significantly larger than that in thefed.
In the sma// and large intestine, CI. replaeement by glueonate in vitro, indicated that the basa i and eholinergie secretagogue stimulated seeretion were
mainly carried by the C]- ion.
In the ease of starvation, in the sma// intestine in vivo, the basal and bethanechol-stimulated fluid transport eonflrmed the lack of secretion obtained in
vitro. In the colon, however, the in vivo results did not confirm the hypersecretion induced by bethanechol in vitro.

Kaynakça

  • Ankara Üniversitesi – Ankara Üniversitesi Veteriner Fakültesi Dergisi
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Veteriner Cerrahi
Bölüm Araştırma Makalesi
Yazarlar

Vedat Sağmanlıgil

Yayımlanma Tarihi 1 Ocak 1995
Yayımlandığı Sayı Yıl 1995

Kaynak Göster

APA Sağmanlıgil, V. (1995). EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 42(03). https://doi.org/10.1501/Vetfak_0000000761
AMA Sağmanlıgil V. EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE. Ankara Univ Vet Fak Derg. Ocak 1995;42(03). doi:10.1501/Vetfak_0000000761
Chicago Sağmanlıgil, Vedat. “EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 42, sy. 03 (Ocak 1995). https://doi.org/10.1501/Vetfak_0000000761.
EndNote Sağmanlıgil V (01 Ocak 1995) EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE. Ankara Üniversitesi Veteriner Fakültesi Dergisi 42 03
IEEE V. Sağmanlıgil, “EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE”, Ankara Univ Vet Fak Derg, c. 42, sy. 03, 1995, doi: 10.1501/Vetfak_0000000761.
ISNAD Sağmanlıgil, Vedat. “EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 42/03 (Ocak 1995). https://doi.org/10.1501/Vetfak_0000000761.
JAMA Sağmanlıgil V. EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE. Ankara Univ Vet Fak Derg. 1995;42. doi:10.1501/Vetfak_0000000761.
MLA Sağmanlıgil, Vedat. “EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 42, sy. 03, 1995, doi:10.1501/Vetfak_0000000761.
Vancouver Sağmanlıgil V. EFFECTS OF DIETARY DEPRIVATION ON SMALLAND LARGE INTESTINAL ION TRANSPORT IN THE MOUSE. Ankara Univ Vet Fak Derg. 1995;42(03).