ankara univ vet fak dergAnkara Üniversitesi Veteriner Fakültesi Dergisi1300-08611308-2817Ankara ÜniversitesiThe efficacy of intramammary, systemic and combined antibiotics administered during dry off in cows with subclinical mastitisKuruya çıkartılan ineklerde subklinik mastitislerin önlenmesinde ve sağaltımında meme içi, sistemik ve kombine antibiyotik uygulamalarının etkinlikleriMusalBeyazıtDeparment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, University of Ankara, Diskapi, 06110 Ankaraİzgürİ. HakkıDeparment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, University of Ankara, Diskapi, 06110 Ankara10.1501/Vetfak_0000000091Veterinary SurgeryVeteriner Cerrahi0901200653317517801012006Eighty Brown Swiss cows were randomly assigned to three different therapy groups and a control group each including 20 cows to compare the efficacy of intramammary, systemic and intramammary plus systemic dry cow therapies in the elimination of existing subclinical intramammary infections (IMI) and prevention of new infections occuring in the dry period. Individual quarter milk samples were taken for microbilogical isolation and identification from all cows prior to drying off and without regarding the results, the treatments were administered. Rates of elimination and prevention of IMI and for intramammary and combined therapy group were higher than systemic therapy group. Systemic therapy alone did not provide better results than the control group where no administration were done. The intramammary dry cow product used in this study seems effective in preventing new IMI and eliminating existing IMI. Better results were obtained in the combination therapy group while systemic dry cow therapy alone did not provide effective results in the prevention and elimination of IMI in the dry periodBu çalışmada 80 İsviçre Esmeri inek kullanılmış, bu inekler meme içi, sistemik, sistemik - meme içi kombine ve kontrol grubu olmak üzere 20’ şer inekten oluşan dört farklı kuru dönem sağaltımı grubuna ayrılarak var olan subklinik meme infeksiyonlarını tedavi edici ve koruyucu etkinlikleri karşılaştırılmıştır. Kuru döneme girişte tüm ineklerin her bir meme lobundan ayrı ayrı bireysel süt örnekleri alınarak, mikrobiyolojik izolasyon ve identifikasyon yapılmış, sonuçlara bakılmadan, sağaltımlar uygulanmıştır. Elde edilen sonuçlara göre meme içi ve kombine sağaltım gruplarında kuru dönem sürecinde daha yüksek iyileşme ve koruma oranları elde edilmiştir. Yalnız sistemik sağaltım grubunda hiçbir uygulama yapılmayan kontrol grubuna göre herhangi bir avantaj sağlanamamıştır. Sonuç olarak bu çalışmada kullanılan kuru dönem preparatının var olan enfeksiyonların sağaltımında ve yeni meme içi enfeksiyonların önelenmesinde etkin bir şekilde kullanılabileceği anlaşımıştır. Kombine sağaltım daha iyi sağaltım oranı elde edilirken, tek başına sistemik sağaltım kuru dönemde meme içi enfeksiyonların sağaltımında ve korumada yeterli etkinlik oluşturmadığı görülmüştürCow dry cow therapy prevention subclinical mastitisİnek koruma kuru dönem sağaltımı subklinik mastitislerAli-Vehmas T, Sandholm M (1995): Balance between bacteria and host-the bacteria' s point of view. 49 – 58. In: M Sandholm, T Honkanen-Buzalski, L Kaartinen, S Pyörälä (Eds) The Bovine Udder and Mastitis . Gummerus Kirjapaino oy, Jyväskylä, Finland.Batra TR (1988): Effects of a complete dry cow treatment on mastitis control in dairy cattle. 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(1985): Environmental pathogens and intramammary infection during the dry period. J Dairy Sci, 68, 402-417. Geliş tarihi: 05.01.2006 / Kabul tarihi: 20.02.2006