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Yıl 2023, Cilt: 7 Sayı: 2, 68 - 79, 31.08.2023
https://doi.org/10.30704/http-www-jivs-net.1272983

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Understanding canine aggression: Neurobiological insights for a complex behavior

Yıl 2023, Cilt: 7 Sayı: 2, 68 - 79, 31.08.2023
https://doi.org/10.30704/http-www-jivs-net.1272983

Öz

The relationship between humans and dogs, as the first domesticated animals, exemplifies a significant aspect of human-animal interaction. During domestication, dogs have undergone behavioral changes to establish closer bonds with humans. However, certain dogs face challenges in fully adapting to their new environment, leading to behavioral disorders such as aggression. One of the most prevalent and dangerous behavioral problems in dogs is aggression, which poses risks to both humans and the dogs themselves, sometimes resulting in euthanasia. Canine aggression can arise from various medical and non-medical factors, including physical problems, endocrine system disorders, infectious diseases, central nervous system diseases, hereditary conditions, as well as racial or personal differences. Evaluating aggression based solely on species, breed, and sex characteristics is insufficient. Accurate diagnosis of aggressive behavior requires integrating findings from diverse diagnostic methods, including serum biochemistry, hormone analysis, urinalysis, electroencephalography, radiography, magnetic resonance tests, and behavioral assessments. However, to gain a comprehensive understanding of canine aggression, it is essential to consider the underlying pathophysiological processes and neurobiology. The management of aggressive behavior in dogs necessitates the implementation of diverse treatment strategies aimed at preventing the manifestation of undesirable behaviors. Within the realm of medical interventions, neutering and pharmacotherapy have emerged as prominent approaches. Neutering has shown effectiveness in mitigating aggression among dogs exhibiting aggressive tendencies. On the other hand, pharmacotherapy involves the utilization of complementary and suppressive pharmacological agents that target primary and intermediate components within the mechanisms underlying aggression. These components encompass neurotransmitter/neuromodulator substances, peptides, enzymes, and hormones, all of which contribute to the pathophysiological processes of aggression. Through the modulation of these factors, pharmacotherapy seeks to offer a comprehensive treatment approach for addressing aggressive behavior in dogs. This review aims to investigate the neurobiological basis of aggression in dogs, considering the underlying pathophysiological processes and the role of neurotransmitter/neuromodulator substances, neuropeptides, peptides, enzyme systems, and hormones. Accurate diagnosis and understanding of canine aggression are crucial for the development of effective medical and alternative treatment methods.

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  • Weisman, O., Zagoory-Sharon, O., Schneiderman, I., Gordon, I., Feldman, R. (2013). Plasma oxytocin distributions in a large cohort of women and men and their gender-specific associations with anxiety, Psychoneuroendocrinology, 38, (5), 694-701.
  • Whybrow, P. C. and Prange, A. J. (1981). A hypothesis of thyroid-catecholaminereceptor interaction: its relevance to affective illness. Archives of General Psychiatry, 38(1), 106–113.
  • Wright, H. F., Mills, D. S., Pollux, P. M. J. (2012). Behavioural and physiological correlates of impulsivity in the domestic dog (Canis familiaris). Physiology and Behaviour, 105(3), 676-682.
  • Yeon, S. C., Erb, H. N., Houpt, K. A. (1999). A retrospective study of canine house soiling: Diagnosis and treatment, 35, 101-106.
  • Yoshida, M., Takayanagi, Y., Inoue, K., Kimura, T., Young, L. J., Onaka, T. (2009). Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice. Journal of Neuroscience, 29, 2259-2271. Yu, C. J., Zhang, S. W., Tai, F. D. (2016). Effects of nucleus accumbens oxytocin and its antagonist on social approach behavior. Behavioral Pharmacology, 27, 672–680.
  • Yu, Q., Teixeira, C. M., Mahadevia, D., Huang, Y., Balsam, D., Mann, J. J., Gingrich, J. A., Ansorge, M. S. (2014). Dopamine and serotonin signaling during two sensitive developmental periods differentially impact adult aggressive and affective behaviors in mice. Molecular Psychiatry, 19(6), 688-698.
  • Zapata, I., Serpell, J. A., Alvarez, C. E. (2016). Genetic mapping of canine fear and aggression. BMC Genomics, 17, 572.
Toplam 133 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Veteriner Cerrahi
Bölüm Derleme Makaleler
Yazarlar

Gökçen Güvenç Bayram 0000-0002-1413-3651

Zeynep Semen 0000-0002-7722-5772

Yayımlanma Tarihi 31 Ağustos 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 7 Sayı: 2

Kaynak Göster

APA Güvenç Bayram, G., & Semen, Z. (2023). Understanding canine aggression: Neurobiological insights for a complex behavior. Journal of Istanbul Veterinary Sciences, 7(2), 68-79. https://doi.org/10.30704/http-www-jivs-net.1272983

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