Use of the hypertonic saline-dextran and oral electrolyte solution for fluid resuscitation of dehydrated diarrheic calves
Öz
his study was aimed to investigate the effectiveness of the hypertonic saline-dextran (HSD) and oral electrolyte
solution (OES) for l1uid resuscitation in dehydrated diarrheic calves. Twelve calves aged 1-5 day-old were used. HSD (7.2%
NaCI+6% dextran 70), once 4 ml/kg i.v. and OES (3.22 g/L NaCl, 1.12 g/L KCl, 4.76 g/L sodium acetate, 16.22 g/L glucose) 55 ml/
kg q 8 h p.o. were administered. Clinical and laboratory evaluations were performed before the treatment and 4, 24 and 48. hours onwards. The RBC, HCT, Hb, WBC, PC02 and total protein values in 4. and 24. h. ~ere significantly (p<0.05) decreased compared to
those of before the treatmenl. While decrease (pand total protein values in 48. h. were statistically indifferenl. The pH, BE and HC03' values in 4, 24 and 48. h. were significantly
(pCrypıosporidium infection. As a result, it was concluded that fluid resuscitation using hipertonic saline-dextran and oral electrolyte
solution in calves with diarrhea was highly effective and practical)>,05)>
Anahtar Kelimeler
Kaynakça
- Booth AJ, Naylor JM (1987): Correction ofmetaholic dosis in diarrhealcalves hy oral administration aci- of elect- rolyte solu tion s with or without hicarhonate. JA VMA, ,62-68. Constable PD, Gohar HM, Morin DE, Thurmon JC (1996):Use of hypertonic saline-dextran solution to re- suscitate hypovolemiccalves with diarrhea. AJVR, 57, 97- Constable PD, Walker PG, MorinDE, Foreman JH
- (1998): Clinical and lahoratOlY assesment of hydration sta- tus of neonatalcalves with diarrhea.JA VMA, 212, 991
- Dubick MA, Zaucha GM, KorteDW, Wade CE (1993)
- Acute and suhacute toxicity of7.5%Hypertonicsaline-6% Dextran 70 (HSD) in dogs. 2. Biochemical and behavioral responses. J Appl Toxicol, 13, 49-55. Elgio Gl, Mathew BP, Poli de Figueriedo LF, Schenerts PJ, Horton JW, Dubick MA, Kramer GC (1998): Re- suscitation with hypertonic saline dextran improves cardiac function in vivo and ex vivo af ter huminjury in sheep. Shock, 9, 375-383.
- Garry F, Chew DJ, Hoffsis GH (1990): Urinary indices of renal nephrotoxicosis. AJVR, 51, 420-427.
- GradwohlRBH (1956): Clinical LahoratoryMethod and Diagnosis.
- Volı.5. Ed. The CV Mosby Company, St. Louis. Griffel MI, Kaufman BS (1992): Fluid resuscitation of the criticallyili; Pharmacology of collaids and crystal- laids. Crit Care Clin, 8, 235. Aslan Kalınbacak i i Groutides C, Michell AR (1990):Changes In plasma composltlon
- In calves survlvlng br dylng from dlarrhoea. i i C, Miehell AR (1990): Evaluatlon oj'acid-base GrouUdes dlsıurbancesIn caifdlarrhoae. Ybt Rec, 126, 29-31. ıI.
- Hess JR, DubiekMA, SummarlyJJ, Bangal NR, Wade CE(1992): The e.tfects of7.5%NaCl-6%dextran on ca- i agulaıloıı and platelet aggregatlon In humans. J Trauma, i i MA, Wade CE, Gunther i Ho HS, Sondeen JL, Dubiek
- % dextran70during hemorrHaglc shock in swine: eFFects i ~~' Olıorgan bloadilaw. Cri t Care Med, 5, 1121-1126.
- (1998): The varlous types ofparenteralflu- i Mathews ıds and their Indlcations. Yet
- Naylor JM, Petrle L, Rorigu~z MI (1990): A comparlsOli oj' three oral elecırolyte arrheic calves. Can Yet J, 31, 153-760. solutlons In the treatment of dl- Philips
- RW (1985): Fluld thJrapy for diarrhoelc whaı, how and how mucJı. Yet Clin North Am Food Anim i i Pract, 3, 541-562.
- Suzuki K, Ogino R, NishinalM, Kohama A (1995):EL fecıs oj' hypertonic saline and ıdextran70on cardlac func- ıions af ter bunıs. Am J Physio;l, 268, 856-864. Sümbüloğlu K, Sümbüloğl~ Y (1995): Blyoistatlstlk.
- Baskı. Özdemir Yayıncılık, Ahkara. i i i i i i i i i i i i i i i i i i Şahal M, Kurtdede Tobias TA, Sehertel Valaseo IT, Rocha-Silva Walker A, Börkü MK, ünsürıln H, İmren H, Özlem MB, KalInbacak A (1994): Yenı doğan ishall buzağılarmklinik bulguları ve asit baz dengesi dikkate alı- narak sodyum bikarbonatve elektrolitik slvııJrla sağaltımı.
- Wall PL, NelsonLM, Guthmiller j LA11996): Cost er fectlveness calves with severe dlarrhea. JA YMA, 209, 1714-1715. White WL, Erickson
- MM, Stevens SC (1976): Chemistry for the Clinical Laboratory. Company, St Louis.
- Fourth Ed. The CY Mosby Geliş tarihi: 14.10.2002 / Kabul tarihi: 30.10.2002
İshaııi buzağıların sıvı sağaitımında hipertonik salin-dextran ve oral elektrolit solüsyonunun kuııanımı
Öz
: Bu çalışmada ishalli dehidre buzağıların sıvı sağaitımında hipertonik salin-dextran (HSD) ve oral elektrolit solüsyonun
(OES) etkinliğinin araştırılması amaçlandı. Çalışmada 1-5 günlük 12 buzağı kullanıldı. HSD (%7.2 NaCI+%6 dextran 70), 4 ml/kg
dozunda bir kez damar içi ve OES (3.22 g/L NaCl, 1.12 g/L KCl, 4.76 g/L sodyum asetat, 16.22 g/L glükoz) 55 ml/kg dozunda 8 saat
ara ile 3 kez oral kullanıldı. Klinik ve laboratuvar değerlendirmeler sağaItım öncesi, sağaitım sonrası 4, 24 ve 48. saatlerde yapıldı.
Dördüncü ve 24. saatlerde, RBC, HCT, Hb, WBC, PC02 ve total protein değerleri sağaItım öncesi değerlerine göre önemli (p<0.05)
düşüşler gösterdi. Kırk sekizinci saatte WBC ve Hb değerleri azalmaya (p<0,05) devam ederken, RBC, HCT, PC02 ve total protein
değerlerindeki değişiklikler önemli bulunmadı. Sağaitım sonrası 4, 24 ve 48. saatlerde pH, BE ve HC03' değerleri sağaItım öncesi
değerlerine göre önemli (p24. saatte önemli oranda yüksek olduğu saptandı (p<0.05). Çalışmada LO buzağı iyileşirken, 2 buzağı şiddetli septisemi ve/veya kriptosporidium enfeksiyonundan öldü. Sonuç olarak, ishalli buzağılarda hipertonik salin-dextran ve oral elektrolit solüsyonu kul.
lanılarak yapılan sıvı sağaitımının oldukça etkili ve pratik olduğu kanısına varıldı)>
Anahtar Kelimeler
Kaynakça
- Booth AJ, Naylor JM (1987): Correction ofmetaholic dosis in diarrhealcalves hy oral administration aci- of elect- rolyte solu tion s with or without hicarhonate. JA VMA, ,62-68. Constable PD, Gohar HM, Morin DE, Thurmon JC (1996):Use of hypertonic saline-dextran solution to re- suscitate hypovolemiccalves with diarrhea. AJVR, 57, 97- Constable PD, Walker PG, MorinDE, Foreman JH
- (1998): Clinical and lahoratOlY assesment of hydration sta- tus of neonatalcalves with diarrhea.JA VMA, 212, 991
- Dubick MA, Zaucha GM, KorteDW, Wade CE (1993)
- Acute and suhacute toxicity of7.5%Hypertonicsaline-6% Dextran 70 (HSD) in dogs. 2. Biochemical and behavioral responses. J Appl Toxicol, 13, 49-55. Elgio Gl, Mathew BP, Poli de Figueriedo LF, Schenerts PJ, Horton JW, Dubick MA, Kramer GC (1998): Re- suscitation with hypertonic saline dextran improves cardiac function in vivo and ex vivo af ter huminjury in sheep. Shock, 9, 375-383.
- Garry F, Chew DJ, Hoffsis GH (1990): Urinary indices of renal nephrotoxicosis. AJVR, 51, 420-427.
- GradwohlRBH (1956): Clinical LahoratoryMethod and Diagnosis.
- Volı.5. Ed. The CV Mosby Company, St. Louis. Griffel MI, Kaufman BS (1992): Fluid resuscitation of the criticallyili; Pharmacology of collaids and crystal- laids. Crit Care Clin, 8, 235. Aslan Kalınbacak i i Groutides C, Michell AR (1990):Changes In plasma composltlon
- In calves survlvlng br dylng from dlarrhoea. i i C, Miehell AR (1990): Evaluatlon oj'acid-base GrouUdes dlsıurbancesIn caifdlarrhoae. Ybt Rec, 126, 29-31. ıI.
- Hess JR, DubiekMA, SummarlyJJ, Bangal NR, Wade CE(1992): The e.tfects of7.5%NaCl-6%dextran on ca- i agulaıloıı and platelet aggregatlon In humans. J Trauma, i i MA, Wade CE, Gunther i Ho HS, Sondeen JL, Dubiek
- % dextran70during hemorrHaglc shock in swine: eFFects i ~~' Olıorgan bloadilaw. Cri t Care Med, 5, 1121-1126.
- (1998): The varlous types ofparenteralflu- i Mathews ıds and their Indlcations. Yet
- Naylor JM, Petrle L, Rorigu~z MI (1990): A comparlsOli oj' three oral elecırolyte arrheic calves. Can Yet J, 31, 153-760. solutlons In the treatment of dl- Philips
- RW (1985): Fluld thJrapy for diarrhoelc whaı, how and how mucJı. Yet Clin North Am Food Anim i i Pract, 3, 541-562.
- Suzuki K, Ogino R, NishinalM, Kohama A (1995):EL fecıs oj' hypertonic saline and ıdextran70on cardlac func- ıions af ter bunıs. Am J Physio;l, 268, 856-864. Sümbüloğlu K, Sümbüloğl~ Y (1995): Blyoistatlstlk.
- Baskı. Özdemir Yayıncılık, Ahkara. i i i i i i i i i i i i i i i i i i Şahal M, Kurtdede Tobias TA, Sehertel Valaseo IT, Rocha-Silva Walker A, Börkü MK, ünsürıln H, İmren H, Özlem MB, KalInbacak A (1994): Yenı doğan ishall buzağılarmklinik bulguları ve asit baz dengesi dikkate alı- narak sodyum bikarbonatve elektrolitik slvııJrla sağaltımı.
- Wall PL, NelsonLM, Guthmiller j LA11996): Cost er fectlveness calves with severe dlarrhea. JA YMA, 209, 1714-1715. White WL, Erickson
- MM, Stevens SC (1976): Chemistry for the Clinical Laboratory. Company, St Louis.
- Fourth Ed. The CY Mosby Geliş tarihi: 14.10.2002 / Kabul tarihi: 30.10.2002
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Veteriner Cerrahi |
| Bölüm | Araştırma Makalesi |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Haziran 2003 |
| Yayımlandığı Sayı | Yıl 2003Cilt: 50 Sayı: 2 |