Recent developments in molecular genetics and statistics have
allowed the identification and use of major genes to explain the genetic
variation. In this context, segregation analysis is a fast, reliable and
inexpensive method that uses only phenotype and pedigree information. The aim
of this study was to examine whether body weight, feed intake, and feed
efficiency in a mouse population are directed by major gene in addition to
polygenic and major gene effects by segregation analysis. For this purpose,
previously collected dataset was used (n= 661). In this study, genetic
variance, error variance, major gene variance, additive and dominant gene
effects were estimated by segregation analyses. Dominant variance (1.04) was
found to be smaller than the additive genetic variance (7.32) for body weight.
Polygenic and major gene heritability predicted as 0.29 (± 0.63) and 0.81 (±
0.98) for body weight, 0.35 (± 0.63) and 0.96 (± 0.98) for feed intake and 0.52
(± 0.63) and 0.81 (± 0.98) for feed efficiency respectively. Existence of major
gene was determined by examining the highest probability density regions.
Although the major gene has been identified for body weight and feed intake,
this result is not confirmed by the Mendelian transmission probabilities.
Bayesian analyses, gibbs sampling, major gene, quantitative phenotype, segregation analyses
Birincil Dil | İngilizce |
---|---|
Konular | Veteriner Cerrahi |
Bölüm | Makaleler |
Yazarlar |
|
Yayımlanma Tarihi | 9 Eylül 2019 |
Yayınlandığı Sayı | Yıl 2019Cilt: 66 Sayı: 4 |
Bibtex | @araştırma makalesi { auvfd445947, journal = {Ankara Üniversitesi Veteriner Fakültesi Dergisi}, issn = {1300-0861}, eissn = {1308-2817}, address = {}, publisher = {Ankara Üniversitesi}, year = {2019}, volume = {66}, number = {4}, pages = {325 - 330}, doi = {10.33988/auvfd.445947}, title = {Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population}, key = {cite}, author = {Karacaören, Burak and Moslem, İssam} } |
APA | Karacaören, B. & Moslem, İ. (2019). Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population . Ankara Üniversitesi Veteriner Fakültesi Dergisi , 66 (4) , 325-330 . DOI: 10.33988/auvfd.445947 |
MLA | Karacaören, B. , Moslem, İ. "Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population" . Ankara Üniversitesi Veteriner Fakültesi Dergisi 66 (2019 ): 325-330 <https://vetjournal.ankara.edu.tr/tr/pub/issue/47708/445947> |
Chicago | Karacaören, B. , Moslem, İ. "Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population". Ankara Üniversitesi Veteriner Fakültesi Dergisi 66 (2019 ): 325-330 |
RIS | TY - JOUR T1 - Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population AU - BurakKaracaören, İssamMoslem Y1 - 2019 PY - 2019 N1 - doi: 10.33988/auvfd.445947 DO - 10.33988/auvfd.445947 T2 - Ankara Üniversitesi Veteriner Fakültesi Dergisi JF - Journal JO - JOR SP - 325 EP - 330 VL - 66 IS - 4 SN - 1300-0861-1308-2817 M3 - doi: 10.33988/auvfd.445947 UR - https://doi.org/10.33988/auvfd.445947 Y2 - 2019 ER - |
EndNote | %0 Ankara Üniversitesi Veteriner Fakültesi Dergisi Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population %A Burak Karacaören , İssam Moslem %T Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population %D 2019 %J Ankara Üniversitesi Veteriner Fakültesi Dergisi %P 1300-0861-1308-2817 %V 66 %N 4 %R doi: 10.33988/auvfd.445947 %U 10.33988/auvfd.445947 |
ISNAD | Karacaören, Burak , Moslem, İssam . "Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population". Ankara Üniversitesi Veteriner Fakültesi Dergisi 66 / 4 (Eylül 2019): 325-330 . https://doi.org/10.33988/auvfd.445947 |
AMA | Karacaören B. , Moslem İ. Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population. Ankara Univ Vet Fak Derg. 2019; 66(4): 325-330. |
Vancouver | Karacaören B. , Moslem İ. Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population. Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2019; 66(4): 325-330. |
IEEE | B. Karacaören ve İ. Moslem , "Investigation on presence of major gene for body weight, feed intake and feed efficiency using a segregation analyses in a mice population", Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 66, sayı. 4, ss. 325-330, Eyl. 2019, doi:10.33988/auvfd.445947 |