Three male calves with a dark mass, hanging down on the skin at various parts of the body, were presented for
clinical examination. All masses were present at the birth of the calves and their size increased with time. The masses were extirpated
by a routine surgical operation and presented for histopathological examination. Tumour cells having cytoplasmic melanin granules
showed a round or spindle-shaped nuclei. The mean mitotic rate was 5-7 at a high power field. Neoplastic melanocytes displayed an
evident cytoplasmic immunolabeling to Melan A, HMB-45, S-100, NSE, and Vimentin. Tumour cells showed a nuclear positivity for
Ki-67. Nuclear pleomorphism and a high mitotic rate along with the positive reaction of neoplastic cells to the melanocytic markers
were indicative of melanoma. Nevertheless, neoplasms originating from melanocytes always need advanced imaging techniques along
with histopathological and immunohistochemical examination while assessing biological behavior of the tumour.
Calves, congenital cutaneous melanoma, histopathology, immunohistochemistry.
Birincil Dil | İngilizce |
---|---|
Konular | Veteriner Cerrahi |
Bölüm | Kısa Bildiri |
Yazarlar |
|
Yayımlanma Tarihi | 9 Kasım 2018 |
Yayınlandığı Sayı | Yıl 2018Cilt: 65 Sayı: 4 |
Bibtex | @kısa bildiri { auvfd635516, journal = {Ankara Üniversitesi Veteriner Fakültesi Dergisi}, issn = {1300-0861}, eissn = {1308-2817}, address = {}, publisher = {Ankara Üniversitesi}, year = {2018}, volume = {65}, number = {4}, pages = {425 - 432}, doi = {10.1501/Vetfak\_0000002877}, title = {Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases)}, key = {cite}, author = {Beytut, Enver and Kılıç, Engin and Yayla, Sadık} } |
APA | Beytut, E. , Kılıç, E. & Yayla, S. (2018). Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases) . Ankara Üniversitesi Veteriner Fakültesi Dergisi , 65 (4) , 425-432 . DOI: 10.1501/Vetfak_0000002877 |
MLA | Beytut, E. , Kılıç, E. , Yayla, S. "Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases)" . Ankara Üniversitesi Veteriner Fakültesi Dergisi 65 (2018 ): 425-432 <http://vetjournal.ankara.edu.tr/tr/pub/issue/49588/635516> |
Chicago | Beytut, E. , Kılıç, E. , Yayla, S. "Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases)". Ankara Üniversitesi Veteriner Fakültesi Dergisi 65 (2018 ): 425-432 |
RIS | TY - JOUR T1 - Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases) AU - EnverBeytut, EnginKılıç, SadıkYayla Y1 - 2018 PY - 2018 N1 - doi: 10.1501/Vetfak_0000002877 DO - 10.1501/Vetfak_0000002877 T2 - Ankara Üniversitesi Veteriner Fakültesi Dergisi JF - Journal JO - JOR SP - 425 EP - 432 VL - 65 IS - 4 SN - 1300-0861-1308-2817 M3 - doi: 10.1501/Vetfak_0000002877 UR - https://doi.org/10.1501/Vetfak_0000002877 Y2 - 2018 ER - |
EndNote | %0 Ankara Üniversitesi Veteriner Fakültesi Dergisi Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases) %A Enver Beytut , Engin Kılıç , Sadık Yayla %T Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases) %D 2018 %J Ankara Üniversitesi Veteriner Fakültesi Dergisi %P 1300-0861-1308-2817 %V 65 %N 4 %R doi: 10.1501/Vetfak_0000002877 %U 10.1501/Vetfak_0000002877 |
ISNAD | Beytut, Enver , Kılıç, Engin , Yayla, Sadık . "Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases)". Ankara Üniversitesi Veteriner Fakültesi Dergisi 65 / 4 (Kasım 2018): 425-432 . https://doi.org/10.1501/Vetfak_0000002877 |
AMA | Beytut E. , Kılıç E. , Yayla S. Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases). Ankara Univ Vet Fak Derg. 2018; 65(4): 425-432. |
Vancouver | Beytut E. , Kılıç E. , Yayla S. Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases). Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2018; 65(4): 425-432. |
IEEE | E. Beytut , E. Kılıç ve S. Yayla , "Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases)", Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 65, sayı. 4, ss. 425-432, Kas. 2018, doi:10.1501/Vetfak_0000002877 |