The c-Abl gene is a nonreceptor tyrosine kinase that has roles in cell growth, control of the cell cycle, initiation of
pronuclear movement and actin cytoskeleton dynamics. The present study has examined the localization of c-Abl protein during oocyte
activation in mouse in vitro. Confocal immunofluorescence analysis showed that c-Abl originates at the cortex with a crescent shape
before the activation and continues up along both sides of the cortex after activation during meiotic division until pronuclear stage.
These results demonstrate that c-Abl may play role in asymmetric division of the egg to produce polar body, positioning of the spindle,
and may regulate the microtubule cytoskeleton or have some roles in this process.
c-Abl, meiotic division, oocyte activation, spindle positioning
Birincil Dil | İngilizce |
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Bölüm | Araştırma Makalesi |
Yazarlar |
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Yayımlanma Tarihi | 31 Aralık 2018 |
Yayınlandığı Sayı | Yıl 2019Cilt: 66 Sayı: 1 |
Bibtex | @araştırma makalesi { auvfd636023, journal = {Ankara Üniversitesi Veteriner Fakültesi Dergisi}, issn = {1300-0861}, eissn = {1308-2817}, address = {}, publisher = {Ankara Üniversitesi}, year = {2019}, volume = {66}, number = {1}, pages = {89 - 93}, title = {Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro}, key = {cite}, author = {Mutluay, Duygu and Öner, Hakan} } |
APA | Mutluay, D. & Öner, H. (2019). Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro . Ankara Üniversitesi Veteriner Fakültesi Dergisi , 66 (1) , 89-93 . Retrieved from http://vetjournal.ankara.edu.tr/tr/pub/issue/49606/636023 |
MLA | Mutluay, D. , Öner, H. "Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro" . Ankara Üniversitesi Veteriner Fakültesi Dergisi 66 (2019 ): 89-93 <http://vetjournal.ankara.edu.tr/tr/pub/issue/49606/636023> |
Chicago | Mutluay, D. , Öner, H. "Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro". Ankara Üniversitesi Veteriner Fakültesi Dergisi 66 (2019 ): 89-93 |
RIS | TY - JOUR T1 - Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro AU - DuyguMutluay, HakanÖner Y1 - 2019 PY - 2019 N1 - DO - T2 - Ankara Üniversitesi Veteriner Fakültesi Dergisi JF - Journal JO - JOR SP - 89 EP - 93 VL - 66 IS - 1 SN - 1300-0861-1308-2817 M3 - UR - Y2 - 2023 ER - |
EndNote | %0 Ankara Üniversitesi Veteriner Fakültesi Dergisi Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro %A Duygu Mutluay , Hakan Öner %T Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro %D 2019 %J Ankara Üniversitesi Veteriner Fakültesi Dergisi %P 1300-0861-1308-2817 %V 66 %N 1 %R %U |
ISNAD | Mutluay, Duygu , Öner, Hakan . "Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro". Ankara Üniversitesi Veteriner Fakültesi Dergisi 66 / 1 (Aralık 2018): 89-93 . |
AMA | Mutluay D. , Öner H. Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro. Ankara Univ Vet Fak Derg. 2019; 66(1): 89-93. |
Vancouver | Mutluay D. , Öner H. Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro. Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2019; 66(1): 89-93. |
IEEE | D. Mutluay ve H. Öner , "Relationships between Abelson tyrosine kinase (c-abl) and spindle during meiotic division in mouse oocyte in vitro", Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 66, sayı. 1, ss. 89-93, Ara. 2018 |