Ankara Üniversitesi Veteriner Fakültesi Dergisi

Öz

The avermectins are macrocyclic lactones produced by
the actinomycete, Streptomyces avermitilis. Ivermectin (22, 23-dihydroavermectin Bı), a clıemica/ly modified derivative, was effective in
tlıe treatment and control of psoroptic mange in sheep. Fourteen Akkaraman sheep natura/ly infected with Psoroptes ovİs were treated
with a single subcutaneous injection of ivermectin at 200 mcg / kg of
body weight. Animals were clinica/ly examined before treatment and
then on a weekly basis up to four weeks after ivermectin inoculation.
Also, .lkin scrapiııgs were collected from each slıeep at weekly intervals to determine the presence or absence of the psoroptic mites. All of the
sheep showed motile mites on the initial skin scrapings. There was no
motile mites in sheep three weeks after treatment. Complete elimination
of psoroptic mange mites occurred in the fourth week after inoculation
of ivermectin.