Yıl 2021, Cilt 68 , Sayı 2, Sayfalar 121 - 127 2021-03-31

Enrofloxacin (ENR) is a broad-spectrum fluoroquinolone antibiotic widely used in both human medicine and veterinary medicine. In this study, the milk-excretion patterns of ENR and its metabolite ciprofloxacin (CIP) were determined up to the 10th milking following the intramuscular administration of ENR (2.5mg/kg of body weight) to lactating dairy buffaloes. The milk of each animal was collected and the concentrations of ENR and CIP were detected in milk by LC-MS/MS. The detection limits of the method were determined for ENR and CIP as 0.35 μg/kg and 0.12 μg/kg, respectively. The highest total mean concentrations of ENR and its metabolite CIP was determined in the second milking after injection as 603 μg/kg. The residue level in all buffalo milk samples was found to be lower than the maximum residue limit (100 μg/kg) at the fifth milking. In addition, the employed method is successfully applied to evaluate the presence of ENR and CIP residue in 50 marketed buffalo milk samples and none of the samples contained these antibiotics. Consequently, the present study provided information on the milk excretion levels of ENR and CIP in Anatolian buffalo milks by an LC-MS/MS method.
Anatolian Buffaloes, Ciprofloxacin, Enrofloxacin, excretion, LC-MS/MS, Milk
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Birincil Dil en
Konular Veteriner Hekimlik
Bölüm Araştırma Makalesi
Yazarlar

Orcid: 0000-0002-1533-4519
Yazar: Ulaş ACARÖZ (Sorumlu Yazar)
Kurum: Afyon Kocatepe University, Faculty of Veterinary Medicine, Department of Food Hygiene and Technology, Afyonkarahisar
Ülke: Turkey


Orcid: 0000-0002-1915-9797
Yazar: Sinan İNCE
Kurum: Afyon Kocatepe University, Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Afyonkarahisar
Ülke: Turkey


Orcid: 0000-0001-9230-6725
Yazar: Damla ARSLAN ACARÖZ
Kurum: Afyon Kocatepe University, Bayat Vocational School, Afyon
Ülke: Turkey


Orcid: 0000-0002-9037-2945
Yazar: Zeki GÜRLER
Kurum: Afyon Kocatepe University, Faculty of Veterinary Medicine, Department of Food Hygiene and Technology, Afyonkarahisar
Ülke: Turkey


Orcid: 0000-0002-9257-7506
Yazar: Recep KARA
Kurum: Afyon Kocatepe University, Faculty of Veterinary Medicine, Department of Food Hygiene and Technology, Afyonkarahisar
Ülke: Turkey


Orcid: 0000-0003-0198-629X
Yazar: İsmail KÜÇÜKKURT
Kurum: Afyon Kocatepe University, Faculty of Veterinary Medicine, Department of Biochemistry, Afyonkarahisar
Ülke: Turkey


Orcid: 0000-0001-8602-2400
Yazar: Abdullah ERYAVUZ
Kurum: Afyon Kocatepe University, Faculty of Veterinary Medicine, Department of Physiology, Afyonkarahisar
Ülke: Turkey


Destekleyen Kurum Afyon Kocatepe University Scientific Research Council
Proje Numarası 17.VF.08
Tarihler

Yayımlanma Tarihi : 31 Mart 2021

Bibtex @araştırma makalesi { auvfd706602, journal = {Ankara Üniversitesi Veteriner Fakültesi Dergisi}, issn = {}, eissn = {1308-2817}, address = {}, publisher = {Ankara Üniversitesi}, year = {2021}, volume = {68}, pages = {121 - 127}, doi = {10.33988/auvfd.706602}, title = {Evaluation of the enrofloxacin excretion in Anatolian buffalo milk}, key = {cite}, author = {Acaröz, Ulaş and İnce, Sinan and Arslan Acaröz, Damla and Gürler, Zeki and Kara, Recep and Küçükkurt, İsmail and Eryavuz, Abdullah} }
APA Acaröz, U , İnce, S , Arslan Acaröz, D , Gürler, Z , Kara, R , Küçükkurt, İ , Eryavuz, A . (2021). Evaluation of the enrofloxacin excretion in Anatolian buffalo milk . Ankara Üniversitesi Veteriner Fakültesi Dergisi , 68 (2) , 121-127 . DOI: 10.33988/auvfd.706602
MLA Acaröz, U , İnce, S , Arslan Acaröz, D , Gürler, Z , Kara, R , Küçükkurt, İ , Eryavuz, A . "Evaluation of the enrofloxacin excretion in Anatolian buffalo milk" . Ankara Üniversitesi Veteriner Fakültesi Dergisi 68 (2021 ): 121-127 <http://vetjournal.ankara.edu.tr/tr/pub/issue/60673/706602>
Chicago Acaröz, U , İnce, S , Arslan Acaröz, D , Gürler, Z , Kara, R , Küçükkurt, İ , Eryavuz, A . "Evaluation of the enrofloxacin excretion in Anatolian buffalo milk". Ankara Üniversitesi Veteriner Fakültesi Dergisi 68 (2021 ): 121-127
RIS TY - JOUR T1 - Evaluation of the enrofloxacin excretion in Anatolian buffalo milk AU - Ulaş Acaröz , Sinan İnce , Damla Arslan Acaröz , Zeki Gürler , Recep Kara , İsmail Küçükkurt , Abdullah Eryavuz Y1 - 2021 PY - 2021 N1 - doi: 10.33988/auvfd.706602 DO - 10.33988/auvfd.706602 T2 - Ankara Üniversitesi Veteriner Fakültesi Dergisi JF - Journal JO - JOR SP - 121 EP - 127 VL - 68 IS - 2 SN - -1308-2817 M3 - doi: 10.33988/auvfd.706602 UR - https://doi.org/10.33988/auvfd.706602 Y2 - 2020 ER -
EndNote %0 Ankara Üniversitesi Veteriner Fakültesi Dergisi Evaluation of the enrofloxacin excretion in Anatolian buffalo milk %A Ulaş Acaröz , Sinan İnce , Damla Arslan Acaröz , Zeki Gürler , Recep Kara , İsmail Küçükkurt , Abdullah Eryavuz %T Evaluation of the enrofloxacin excretion in Anatolian buffalo milk %D 2021 %J Ankara Üniversitesi Veteriner Fakültesi Dergisi %P -1308-2817 %V 68 %N 2 %R doi: 10.33988/auvfd.706602 %U 10.33988/auvfd.706602
ISNAD Acaröz, Ulaş , İnce, Sinan , Arslan Acaröz, Damla , Gürler, Zeki , Kara, Recep , Küçükkurt, İsmail , Eryavuz, Abdullah . "Evaluation of the enrofloxacin excretion in Anatolian buffalo milk". Ankara Üniversitesi Veteriner Fakültesi Dergisi 68 / 2 (Mart 2021): 121-127 . https://doi.org/10.33988/auvfd.706602
AMA Acaröz U , İnce S , Arslan Acaröz D , Gürler Z , Kara R , Küçükkurt İ , Eryavuz A . Evaluation of the enrofloxacin excretion in Anatolian buffalo milk. Ankara Univ Vet Fak Derg. 2021; 68(2): 121-127.
Vancouver Acaröz U , İnce S , Arslan Acaröz D , Gürler Z , Kara R , Küçükkurt İ , Eryavuz A . Evaluation of the enrofloxacin excretion in Anatolian buffalo milk. Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2021; 68(2): 121-127.
IEEE U. Acaröz , S. İnce , D. Arslan Acaröz , Z. Gürler , R. Kara , İ. Küçükkurt ve A. Eryavuz , "Evaluation of the enrofloxacin excretion in Anatolian buffalo milk", Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 68, sayı. 2, ss. 121-127, Mar. 2021, doi:10.33988/auvfd.706602