Yıl 2021, Cilt 68 , Sayı 2, Sayfalar 147 - 154 2021-03-31

Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model

Büşra KİBAR KURT [1] , Ali BELGE [2]


The aim of this study was to evaluate the effect of collagen shield on epithelial wound healing in rabbit eyes. Adult New Zealand Albino rabbits were used in the study. All surgical procedures were carried out under general anesthesia. Superficial keratectomies of 6 mm in diameter were created in 40 eyes of 20 rabbits and they were separated into 3 groups as the control (CN), medical treatment (CA) and collagen barrier (CB) groups. In the CN group, 6 rabbits received 0.9% NaCl drops. In the CA group, 7 rabbits received ciprofloxacin and acetylcysteine. In the CB group, a collagen shield was placed on corneal defect for 72 hours in 7 rabbits. Central corneal thickness was measured using an ultrasound pachymeter. Corneal thickness was determined before and at 72 and 96 hours after surgery. There was a significant increase (CA group: P<0.01, CB group: P<0.001) in corneal thickness at 72 hours. The wound size was evaluated immediately after the surgery, then at 72 and 96 hours. There was a significantly greater healing response in the collagen shield group (P<0.001) compared to the other groups. The earlier wound closure in the CB group may be due to protection and lubrication of the epithelial cells in the margins of the fresh wound. These findings suggest that the collagen shield may be useful when treating corneal surface conditions in which de-epithelialization is a component.
collagen barrier, collagen shield, cornea wound, rabbit
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Birincil Dil en
Konular Veteriner Hekimlik
Bölüm Araştırma Makalesi
Yazarlar

Orcid: 0000-0002-1490-8832
Yazar: Büşra KİBAR KURT (Sorumlu Yazar)
Kurum: Aydın Adnan Menderes University, Faculty of Veterinary Medicine, Department of Surgery
Ülke: Turkey


Orcid: 0000-0003-3346-6926
Yazar: Ali BELGE
Kurum: Aydın Adnan Menderes University, Faculty of Veterinary Medicine, Department of Surgery
Ülke: Turkey


Tarihler

Yayımlanma Tarihi : 31 Mart 2021

Bibtex @araştırma makalesi { auvfd724013, journal = {Ankara Üniversitesi Veteriner Fakültesi Dergisi}, issn = {}, eissn = {1308-2817}, address = {}, publisher = {Ankara Üniversitesi}, year = {2021}, volume = {68}, pages = {147 - 154}, doi = {10.33988/auvfd.724013}, title = {Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model}, key = {cite}, author = {Kibar Kurt, Büşra and Belge, Ali} }
APA Kibar Kurt, B , Belge, A . (2021). Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model . Ankara Üniversitesi Veteriner Fakültesi Dergisi , 68 (2) , 147-154 . DOI: 10.33988/auvfd.724013
MLA Kibar Kurt, B , Belge, A . "Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model" . Ankara Üniversitesi Veteriner Fakültesi Dergisi 68 (2021 ): 147-154 <http://vetjournal.ankara.edu.tr/tr/pub/issue/60673/724013>
Chicago Kibar Kurt, B , Belge, A . "Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model". Ankara Üniversitesi Veteriner Fakültesi Dergisi 68 (2021 ): 147-154
RIS TY - JOUR T1 - Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model AU - Büşra Kibar Kurt , Ali Belge Y1 - 2021 PY - 2021 N1 - doi: 10.33988/auvfd.724013 DO - 10.33988/auvfd.724013 T2 - Ankara Üniversitesi Veteriner Fakültesi Dergisi JF - Journal JO - JOR SP - 147 EP - 154 VL - 68 IS - 2 SN - -1308-2817 M3 - doi: 10.33988/auvfd.724013 UR - https://doi.org/10.33988/auvfd.724013 Y2 - 2020 ER -
EndNote %0 Ankara Üniversitesi Veteriner Fakültesi Dergisi Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model %A Büşra Kibar Kurt , Ali Belge %T Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model %D 2021 %J Ankara Üniversitesi Veteriner Fakültesi Dergisi %P -1308-2817 %V 68 %N 2 %R doi: 10.33988/auvfd.724013 %U 10.33988/auvfd.724013
ISNAD Kibar Kurt, Büşra , Belge, Ali . "Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model". Ankara Üniversitesi Veteriner Fakültesi Dergisi 68 / 2 (Mart 2021): 147-154 . https://doi.org/10.33988/auvfd.724013
AMA Kibar Kurt B , Belge A . Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model. Ankara Univ Vet Fak Derg. 2021; 68(2): 147-154.
Vancouver Kibar Kurt B , Belge A . Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model. Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2021; 68(2): 147-154.
IEEE B. Kibar Kurt ve A. Belge , "Investigation of the effectiveness of dehydrated corneal collagen barriers on corneal defects: An experimental rabbit model", Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 68, sayı. 2, ss. 147-154, Mar. 2021, doi:10.33988/auvfd.724013