Araştırma Makalesi
Yıl 2019,
Cilt: 5 Sayı: 1, 54 - 61, 29.03.2019
Öz
Kaynakça
- REFERENCES 1. Dawson C, Togni B, Moore TE, Jr. Structural changes in chronic herpetic keratitis. Studied by light and electron microscopy. Arch Ophthalmol. 1968;79: 740-7. 2. Baringer JR, Swoveland P. Recovery of herpes-simplex virus from human trigeminal ganglions. N Engl J Med. 1973;288: 648-50. 3. Aronson SB, Moore TE, Jr. Corticosteroid therapy in central stromal keratitis. Am J Ophthalmol. 1969;67: 873-96. 4. Koizumi N, Nishida K, Adachi W, et al. Detection of herpes simplex virus DNA in atypical epithelial keratitis using polymerase chain reaction. Br J Ophthalmol. 1999;83: 957- 60. 5. Tei M, Nishida K, Kinoshita S. Polymerase chain reaction detection of herpes simplex virus in tear fluid from atypical herpetic epithelial keratitis after penetrating keratoplasty. Am J Ophthalmol. 1996;122: 732-5. 6. Howcroft MJ, Breslin CW. Herpes simplex keratitis in renal transplant recipients. Can Med Assoc J. 1981;124: 292-4. 7. Kremer I, Wagner A, Shmuel D, Yussim A, Shapira Z. Herpes simplex keratitis in renal transplant patients. Br J Ophthalmol. 1991;75: 94-6. 8. Rowley AH, Whitley RJ, Lakeman FD, Wolinsky SM. Rapid detection of herpes- simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis. Lancet. 1990;335: 440-1. 9. Kowalski RP, Gordon YJ, Romanowski EG, Araullo-Cruz T, Kinchington PR. A comparison of enzyme immunoassay and polymerase chain reaction with the clinical examination for diagnosing ocular herpetic disease. Ophthalmology. 1993;100: 530-3. 10. Crouse CA, Pflugfelder SC, Pereira I, Cleary T, Rabinowitz S, Atherton SS. Detection of herpes viral genomes in normal and diseased corneal epithelium. Curr Eye Res. 1990;9: 569-81. 11. Mietz H, Cassinotti P, Siegl G, Kirchhof B, Krieglstein GK. Detection of herpes simplex virus after penetrating keratoplasty by polymerase chain reaction: correlation of clinical and laboratory findings. Graefes Arch Clin Exp Ophthalmol. 1995;233: 714-6. 12. Klareskog L, Forsum U, Tjernlund UM, Rask L, Peterson PA. Expression of Ia antigen-like molecules on cells in the corneal epithelium. Invest Ophthalmol Vis Sci. 1979;18: 310-3. 13. Rodrigues MM, Rowden G, Hackett J, Bakos I. Langerhans cells in the normal conjunctiva and peripheral cornea of selected species. Invest Ophthalmol Vis Sci. 1981;21: 759-65. 14. Gillette TE, Chandler JW, Greiner JV. Langerhans cells of the ocular surface. Ophthalmology. 1982;89: 700-11. 15. Bergstresser PR, Fletcher CR, Streilein JW. Surface densities of Langerhans cells in relation to rodent epidermal sites with special immunologic properties. J Invest Dermatol. 1980;74: 77-80. 16. Kelley JG, Ohashi Y, Friedlaender MH. Langerhans cell alterations in the guinea pig cornea. Invest Ophthalmol Vis Sci. 1985;26: 1293-6. 17. Rowden G. Expression of Ia antigens on Langerhans cells in mice, guinea pigs, and man. J Invest Dermatol. 1980;75: 22-31. 18. Brown J, Soderstrom CW, Winkelmann RK. Langerhans' cells in guinea pig cornea: response to chemical injury. Invest Ophthalmol. 1968;7: 668-71. 19. Lang RM, Friedlaender MH, Schoenrock BJ. A new morphologic manifestation of Langerhans cells in guinea pig corneal transplants. Curr Eye Res. 1981;1: 161-7. 20. Asbell PA, Kamenar T. The response of Langerhans cells in the cornea to herpetic keratitis. Curr Eye Res. 1987;6: 179-82.
Yıl 2019,
Cilt: 5 Sayı: 1, 54 - 61, 29.03.2019
Öz
We
aimed to report a case of atypical herpetic keratitis that developed after
renal transplantation. A 48-year-old woman presented with redness, photophobia,
tearing, foreign body, sensation and decreased vision in the left eye. The
patient had undergone renal transplantation 6 months ago, was being treated by
systemic immunosuppressants. (Cyclosporine A, mycophenolate mofetil and
prednisolone acetate). Examination revealed Dellen ulcers and dendriform
lesions which were parallel to the limbus, extending from the temporal area
upper-quadrant to the nasal area. Based on the clinical findings, atypical
herpes simplex virus keratitis (HSVK) was suspected. The subsequent corneal
scraping and real-time polymerase chain reaction (PCR) analysis yielded a positive
result for Herpes Simplex Virus Type 1 (HSV-1) genome. Topical and systemic
acyclovir therapies were prescribed. One week later, the dendriform lesions
showed significant improvement and healed completely within 3 weeks. In
immunocompromised patients, herpetic keratitis can appear in unusual
presentations. Patient on immunosuppressive treatment with suspected herpetic
keratitis, early topical and systemic antiviral therapy may prevent permanent
vision loss and sequelae.
Anahtar Kelimeler
Kaynakça
- REFERENCES 1. Dawson C, Togni B, Moore TE, Jr. Structural changes in chronic herpetic keratitis. Studied by light and electron microscopy. Arch Ophthalmol. 1968;79: 740-7. 2. Baringer JR, Swoveland P. Recovery of herpes-simplex virus from human trigeminal ganglions. N Engl J Med. 1973;288: 648-50. 3. Aronson SB, Moore TE, Jr. Corticosteroid therapy in central stromal keratitis. Am J Ophthalmol. 1969;67: 873-96. 4. Koizumi N, Nishida K, Adachi W, et al. Detection of herpes simplex virus DNA in atypical epithelial keratitis using polymerase chain reaction. Br J Ophthalmol. 1999;83: 957- 60. 5. Tei M, Nishida K, Kinoshita S. Polymerase chain reaction detection of herpes simplex virus in tear fluid from atypical herpetic epithelial keratitis after penetrating keratoplasty. Am J Ophthalmol. 1996;122: 732-5. 6. Howcroft MJ, Breslin CW. Herpes simplex keratitis in renal transplant recipients. Can Med Assoc J. 1981;124: 292-4. 7. Kremer I, Wagner A, Shmuel D, Yussim A, Shapira Z. Herpes simplex keratitis in renal transplant patients. Br J Ophthalmol. 1991;75: 94-6. 8. Rowley AH, Whitley RJ, Lakeman FD, Wolinsky SM. Rapid detection of herpes- simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis. Lancet. 1990;335: 440-1. 9. Kowalski RP, Gordon YJ, Romanowski EG, Araullo-Cruz T, Kinchington PR. A comparison of enzyme immunoassay and polymerase chain reaction with the clinical examination for diagnosing ocular herpetic disease. Ophthalmology. 1993;100: 530-3. 10. Crouse CA, Pflugfelder SC, Pereira I, Cleary T, Rabinowitz S, Atherton SS. Detection of herpes viral genomes in normal and diseased corneal epithelium. Curr Eye Res. 1990;9: 569-81. 11. Mietz H, Cassinotti P, Siegl G, Kirchhof B, Krieglstein GK. Detection of herpes simplex virus after penetrating keratoplasty by polymerase chain reaction: correlation of clinical and laboratory findings. Graefes Arch Clin Exp Ophthalmol. 1995;233: 714-6. 12. Klareskog L, Forsum U, Tjernlund UM, Rask L, Peterson PA. Expression of Ia antigen-like molecules on cells in the corneal epithelium. Invest Ophthalmol Vis Sci. 1979;18: 310-3. 13. Rodrigues MM, Rowden G, Hackett J, Bakos I. Langerhans cells in the normal conjunctiva and peripheral cornea of selected species. Invest Ophthalmol Vis Sci. 1981;21: 759-65. 14. Gillette TE, Chandler JW, Greiner JV. Langerhans cells of the ocular surface. Ophthalmology. 1982;89: 700-11. 15. Bergstresser PR, Fletcher CR, Streilein JW. Surface densities of Langerhans cells in relation to rodent epidermal sites with special immunologic properties. J Invest Dermatol. 1980;74: 77-80. 16. Kelley JG, Ohashi Y, Friedlaender MH. Langerhans cell alterations in the guinea pig cornea. Invest Ophthalmol Vis Sci. 1985;26: 1293-6. 17. Rowden G. Expression of Ia antigens on Langerhans cells in mice, guinea pigs, and man. J Invest Dermatol. 1980;75: 22-31. 18. Brown J, Soderstrom CW, Winkelmann RK. Langerhans' cells in guinea pig cornea: response to chemical injury. Invest Ophthalmol. 1968;7: 668-71. 19. Lang RM, Friedlaender MH, Schoenrock BJ. A new morphologic manifestation of Langerhans cells in guinea pig corneal transplants. Curr Eye Res. 1981;1: 161-7. 20. Asbell PA, Kamenar T. The response of Langerhans cells in the cornea to herpetic keratitis. Curr Eye Res. 1987;6: 179-82.
Toplam 1 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 29 Mart 2019 |
| Gönderilme Tarihi | 6 Mart 2019 |
| Yayımlandığı Sayı | Yıl 2019 Cilt: 5 Sayı: 1 |
