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Feline Herpesvirüs Tip-1 İle Enfekte Kedilerde Vitamin D Düzeyleri

Yıl 2022, Cilt: 10 Sayı: 2, 103 - 107, 26.08.2022

Ecem Duygu Yaz Demiroğlu Mehmet Çağrı Karakurum

https://doi.org/10.24998/maeusabed.1061278

Öz

Bu çalışmada, FeHV-1 ile enfekte kedilerde D vitamin düzeylerinin ölçülmesi ve böylelikle hastalık aktivitesi ile olan ilişkisinin belirlenmesi amaçlandı. Bu çalışmanın hayvan materyalini hastalığa ait klinik semptom gösteren ve yapılan hızlı test ile Feline Herpes Virus enfeksiyonu tanısı konulan değişik ırk, yaş ve cinsiyette 20 adet kedi oluşturdu. Çalışmanın kontrol grubunu ise aşılama amacı ile getirilen rutin fizik muayene ile hemogram ve kan biyokimyası sonuçlarına göre sağlıklı olan ve yapılan hızlı test ile Feline Herpesvirus Tip-1 antijen negatif olarak belirlenen değişik ırk, yaş ve cinsiyette 10 adet kedi oluşturdu. Her iki gruptaki kedilerden alınan kan örnekleri santrifüje edildikten sonra serumları ayrıştırılarak ve analizleri yapılana kadar - 20 °C saklandı. Bu numunelerden daha sonra Florösan immunoassay yöntemi ile 25 hidroksi vitamin D3 düzeyleri belirlendi. FeHV-1 ile enfekte kediler ve sağlıklı kedilerde 25 hidroksi vitamin D3 seviyelerine ait ortalama standart sapma değerleri gruplara göre sırası ile 33,30 ve 64,70 ng/ml olarak saptandı. FeHV-1 ile enfekte kedilerde, serum vitamin D düzeylerinde kontrol grubundaki sağlıklı kedilere göre önemli oranda düşme şekillenmiştir. Sonuç olarak D vitamini eksikliğinin hastalığın oluşumu üzerine etkisi olabilir

Anahtar Kelimeler

Kedi D vitamini Feline Herpes Virüs Tip-1

Destekleyen Kurum

Burdur Mehmet Akif Ersoy Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü

Proje Numarası

0567-YL-19

Kaynakça

  • Autier P., Boniol M., Pizot C., Mullie P., 2014. Vitamin D Status and Ill Health: A Systematic Review. The Lancet Diabetes & Endocrinology 2, 76–89.
  • Berger A., Willi B., Meli ML., Boretti F.S., Hartnack S., Dreyfus A., Lutz H., Hofmann-Lehmann R., 2015. Feline calicivirus and other respiratory pathogens in cats with feline calicivirus-related symptoms and in clinically healthy cats in Switzerland. BMC Veterinary Research 11, 1-12.
  • Burns R.E., Wagner D.C., Leutenegger C.M., Pesavento P.A., 2011. Histologic and molecular correlation in shelter cats with acute upper respiratory infection. Journal of Clinical Microbiology 49, 2454-60.
  • Di Martino B., Di Francesco C.E., Meridiani I., Marsilio F., 2007. Etiological investigation of multiple respiratory infections in cats. New Microbiologica 30, 455-61.
  • Dusso A.S., Brown A.J., Slatopolsky E., 2005. Vitamin D. American Journal of Physiology Renal Physiology 289, 8-28.
  • Filoni C., Catao-Dias J.L., Cattori V., Willi B., Meli M.L., Correa S.H.R., Marques M.C., Adania C.H., Silva C.R., Marvulo M.F.V, Ferreria Neto J.S., Durigon E.L., de Carvalho V.M., Coutinho S.D., Lutz H., Hofmann-Lehmann R., 2012. Surveillance using serological and molecular methods for the detection of infectious agents in captive Brazilian neotropic and exotic felids. Journal of Veterinary Diagnostic Investigation 24, 166-73.
  • Gaskell R., Dawson S., Radford A., Thiry E., 2007. Feline Herpesvirus. Veterinary Research, 38, 337-354.
  • Hassan V., Hassan S., Seyed-Javad P., Ahmad K., Asieh H., Maryam S., Farid F., Siavash A., 2013. Association Between Serum 25 (OH) Vitamin D Concentrations and Inflammatory Bowel Diseases (IBDs) Activity. Medical Journal of Malaysia 68, 34-38.
  • Holick M.F., 2008. Vitamin D: A D-Lightful Health Perspective. Nutrition Reviews 66, 182-194.
  • Jubb, Kennedy, Palmar 2016. Pathology of Domestic Animals. Vol. 2, Sixth Edition, St. Louis Missouri: Elsevier.
  • Jussila A., Virta LJ., Salomaa V., Mäki J., Jula A., Färkkilä M.A., 2013. High and Increasing Prevalence of Inflammatory Bowel Disease in Finland with A Clear North – South Difference. Journal of Crohn’s and Colitis 7, 256-262.
  • Kawaguchi Y., Mikami T., 1995. Molecular interaction between retroviruses and herpesviruses. The Journal of Veterinary Medical Science 57, 811.
  • Kovalik M., Thoday K.L., Evans H., Berry J., van den Broek A.H.M., Mellanby R.J., 2012a. Short-term prednisolone therapy has minimal impact on calcium metabolism in dogs with atopic dermatitis. The Veterinary Journal 193, 439-442.
  • Kovalik M., Thoday K.L., Berry J., van den Broek A.H.M., Mellanby R.J., 2012b. Prednisolone theraphy for atopic dermatitis is less effective in dogs with lower pretreatment serum 25-hydroxyvitamin D concentrations. Veterinary Dermatology 23, 125- e28.
  • Lalor S.M.,, Mellanby R.J., Friend E.J., Bowlt K.L., Berry J., Gunn- Moore D., (2012). Domesticated cats with active mycobacteria infections have low serum vitamin D (25(OH)D) concentrations. Transboundary and Emerging Diseases 59, 279-281.
  • Lalor S., Schwartz A.M., Titmarsh H., Reed N., Tasker S., Boland L., 2014. Cats with inflammatory bowel disease and intestinal small cell lymphoma have low serum concentrations of 25-hydroxyvitamin D. Journal of Veterinary Internal Medicine 28, 351-355.
  • Lim W.C., Hanauer S.B., Li Y.C., 2005. Mechanisms of Disease: Vitamin D and Inflammatory Bowel Disease. Nature Clinical Practice Gastroenterology & Hepatology 2, 103-111.
  • Litster A., Wu C.C., Leutenegger C.M., 2015. Detection of feline upper respiratory tract disease pathogens using a commercially available real-time PCR test. The Veterinary Journal 206, 149-153.
  • Maggs D.J., 2005. Update on Pathogenesis, Diagnosis and Treatment of Feline Herpesvirus Type 1. Clinical Techniques in Small Animal Practice 20, 94-105.
  • McDowell L.R., 2000. Vitamins in Animal and Human Nutrition. 2nd Edition. Iowa: Iowa State University Press.
  • Nicholson I., Dalzell A.M., El-Matary W., 2012. Vitamin D as a Therapy for Colitis: A Systematic Review. Journal of Crohn’s and Colitis 6, 405-411.
  • Özkan B., Döneray H., 2011. D vitamininin iskelet sistemi dışı etkileri. Çocuk Sağlığı ve Hastalıkları Dergisi 54, 99-119.
  • Raman M., Milestone A.N., Walters J.R.F., Hart A.L., Ghosh S., 2011. Vitamin D and Gastrointestinal Diseases: Inflammatory Bowel Disease and Colorectal Cancer. Therapeutic Advances in Gastroenterology 4, 49-62.
  • Stiles J., 2003. Feline Herpesvirus. Clinical Techniques in Small Animal Practice, 18, 178-185.
  • Summers S.C., Ruch-Gallie R., Hawley J.R., Lappin M.R., 2016. Effect of modified live or inactivated feline herpesvirus-1 parenteral vaccines clinical and laborator findings following viral challenge. Journal of Feline Medicine and Surgery, 19, 1-7.
  • Thomasy S.M., Maggs D.J., 2016. A review of antiviral drugs and other compounds with activity against feline herpesvirus type 1. Veterinary Ophthalmology, 19, 119-130.
  • Tilley P., Smith F.W.K., 2008. The 5- Minute Veterinery Consult canine and Feline. İstanbul: Nobel Tıp Kitapevleri, p: 646-647.
  • Titmarsh H.F., Stephanie Lalor M., Tasker S., Barker E.N., Berry J., Gunn- More D., Mellanby R.J., 2015. Vitamin D status in cats with feline immunodeficiency virus. Veterinary Medicine and Science, 1, 72-78.
  • Townsend W, Jacobi S, Tai S, Kiupel M, Wise AG (2013). Ocular and Neural Distribution of Feline Herpesvirus-1 During Active and Latent Experimental Infection in Cats. BMC Veterinary Research, 9, 185.
  • Ulitsky A., Ananthakrishnan A.N., Naik A., Skaros S., Zadvornova Y., Binion D.G., Issa M., 2011. Vitamin D Deficiency in Patients with Inflammatory Bowel Disease. Journal of Parenteral and Enteral Nutrition, 35, 308-316.
  • Waldron J.L., Ashby H.L., Cornes M.P., Bechervaise J.., Razavi C., Thomas O.L., 2013. Vitamin D: a negative acute phase reactant. Journal of Clinical Pathology, 66, 620-622.
  • Weigler B.J., Guy J.S., Nasisse M.P., Hancock S.I., Sherry B., 1997. Effect of a live attenuated intranasal vaccine on latency and shedding of feline herpesvirus 1 in domestic cats. Archives of Virology, 142, 2389-400.

Vitamin D Levels in Cats Infected with Feline Herpesvirus Type-1

Yıl 2022, Cilt: 10 Sayı: 2, 103 - 107, 26.08.2022

Ecem Duygu Yaz Demiroğlu Mehmet Çağrı Karakurum

https://doi.org/10.24998/maeusabed.1061278

Öz

In this study, it was aimed to measure vitamin D levels in Feline Herpesvirus Type-1 (FeHV-1) infected cats and thus to determine its relationship with the disease activity. The animal material of this study was composed of 20 cats of different breeds, ages and genders, which showed clinical symptoms of the disease and were diagnosed with Feline Herpesvirus infection by rapid test. The control group of the study consisted of 10 cats of different breeds, ages and genders, which were healthy according to the results of routine physical examination, laboratory works, which were brought for the purpose of vaccination, and which were determined to be Feline Herpesvirus Type-1 antigen negative with the rapid test. Blood samples were taken from cats in both groups and 25-hydroxy vitamin D3 levels were determined by the fluorescent immunoassay method. The mean standard deviation values of 25 hydroxyvitamin D3 levels in FeHV-1 infected cats and healthy cats were found to be 33.30 and 64.70 ng/ml, respectively. FeHV-1 infected cats showed a significant decrease in serum vitamin D levels compared to healthy cats in the control group. As a result, vitamin D deficiency may have an effect on the formation of the disease.

Anahtar Kelimeler

Cat Feline Herpesvirus Type-1 Vitamin D

Proje Numarası

0567-YL-19

Kaynakça

  • Autier P., Boniol M., Pizot C., Mullie P., 2014. Vitamin D Status and Ill Health: A Systematic Review. The Lancet Diabetes & Endocrinology 2, 76–89.
  • Berger A., Willi B., Meli ML., Boretti F.S., Hartnack S., Dreyfus A., Lutz H., Hofmann-Lehmann R., 2015. Feline calicivirus and other respiratory pathogens in cats with feline calicivirus-related symptoms and in clinically healthy cats in Switzerland. BMC Veterinary Research 11, 1-12.
  • Burns R.E., Wagner D.C., Leutenegger C.M., Pesavento P.A., 2011. Histologic and molecular correlation in shelter cats with acute upper respiratory infection. Journal of Clinical Microbiology 49, 2454-60.
  • Di Martino B., Di Francesco C.E., Meridiani I., Marsilio F., 2007. Etiological investigation of multiple respiratory infections in cats. New Microbiologica 30, 455-61.
  • Dusso A.S., Brown A.J., Slatopolsky E., 2005. Vitamin D. American Journal of Physiology Renal Physiology 289, 8-28.
  • Filoni C., Catao-Dias J.L., Cattori V., Willi B., Meli M.L., Correa S.H.R., Marques M.C., Adania C.H., Silva C.R., Marvulo M.F.V, Ferreria Neto J.S., Durigon E.L., de Carvalho V.M., Coutinho S.D., Lutz H., Hofmann-Lehmann R., 2012. Surveillance using serological and molecular methods for the detection of infectious agents in captive Brazilian neotropic and exotic felids. Journal of Veterinary Diagnostic Investigation 24, 166-73.
  • Gaskell R., Dawson S., Radford A., Thiry E., 2007. Feline Herpesvirus. Veterinary Research, 38, 337-354.
  • Hassan V., Hassan S., Seyed-Javad P., Ahmad K., Asieh H., Maryam S., Farid F., Siavash A., 2013. Association Between Serum 25 (OH) Vitamin D Concentrations and Inflammatory Bowel Diseases (IBDs) Activity. Medical Journal of Malaysia 68, 34-38.
  • Holick M.F., 2008. Vitamin D: A D-Lightful Health Perspective. Nutrition Reviews 66, 182-194.
  • Jubb, Kennedy, Palmar 2016. Pathology of Domestic Animals. Vol. 2, Sixth Edition, St. Louis Missouri: Elsevier.
  • Jussila A., Virta LJ., Salomaa V., Mäki J., Jula A., Färkkilä M.A., 2013. High and Increasing Prevalence of Inflammatory Bowel Disease in Finland with A Clear North – South Difference. Journal of Crohn’s and Colitis 7, 256-262.
  • Kawaguchi Y., Mikami T., 1995. Molecular interaction between retroviruses and herpesviruses. The Journal of Veterinary Medical Science 57, 811.
  • Kovalik M., Thoday K.L., Evans H., Berry J., van den Broek A.H.M., Mellanby R.J., 2012a. Short-term prednisolone therapy has minimal impact on calcium metabolism in dogs with atopic dermatitis. The Veterinary Journal 193, 439-442.
  • Kovalik M., Thoday K.L., Berry J., van den Broek A.H.M., Mellanby R.J., 2012b. Prednisolone theraphy for atopic dermatitis is less effective in dogs with lower pretreatment serum 25-hydroxyvitamin D concentrations. Veterinary Dermatology 23, 125- e28.
  • Lalor S.M.,, Mellanby R.J., Friend E.J., Bowlt K.L., Berry J., Gunn- Moore D., (2012). Domesticated cats with active mycobacteria infections have low serum vitamin D (25(OH)D) concentrations. Transboundary and Emerging Diseases 59, 279-281.
  • Lalor S., Schwartz A.M., Titmarsh H., Reed N., Tasker S., Boland L., 2014. Cats with inflammatory bowel disease and intestinal small cell lymphoma have low serum concentrations of 25-hydroxyvitamin D. Journal of Veterinary Internal Medicine 28, 351-355.
  • Lim W.C., Hanauer S.B., Li Y.C., 2005. Mechanisms of Disease: Vitamin D and Inflammatory Bowel Disease. Nature Clinical Practice Gastroenterology & Hepatology 2, 103-111.
  • Litster A., Wu C.C., Leutenegger C.M., 2015. Detection of feline upper respiratory tract disease pathogens using a commercially available real-time PCR test. The Veterinary Journal 206, 149-153.
  • Maggs D.J., 2005. Update on Pathogenesis, Diagnosis and Treatment of Feline Herpesvirus Type 1. Clinical Techniques in Small Animal Practice 20, 94-105.
  • McDowell L.R., 2000. Vitamins in Animal and Human Nutrition. 2nd Edition. Iowa: Iowa State University Press.
  • Nicholson I., Dalzell A.M., El-Matary W., 2012. Vitamin D as a Therapy for Colitis: A Systematic Review. Journal of Crohn’s and Colitis 6, 405-411.
  • Özkan B., Döneray H., 2011. D vitamininin iskelet sistemi dışı etkileri. Çocuk Sağlığı ve Hastalıkları Dergisi 54, 99-119.
  • Raman M., Milestone A.N., Walters J.R.F., Hart A.L., Ghosh S., 2011. Vitamin D and Gastrointestinal Diseases: Inflammatory Bowel Disease and Colorectal Cancer. Therapeutic Advances in Gastroenterology 4, 49-62.
  • Stiles J., 2003. Feline Herpesvirus. Clinical Techniques in Small Animal Practice, 18, 178-185.
  • Summers S.C., Ruch-Gallie R., Hawley J.R., Lappin M.R., 2016. Effect of modified live or inactivated feline herpesvirus-1 parenteral vaccines clinical and laborator findings following viral challenge. Journal of Feline Medicine and Surgery, 19, 1-7.
  • Thomasy S.M., Maggs D.J., 2016. A review of antiviral drugs and other compounds with activity against feline herpesvirus type 1. Veterinary Ophthalmology, 19, 119-130.
  • Tilley P., Smith F.W.K., 2008. The 5- Minute Veterinery Consult canine and Feline. İstanbul: Nobel Tıp Kitapevleri, p: 646-647.
  • Titmarsh H.F., Stephanie Lalor M., Tasker S., Barker E.N., Berry J., Gunn- More D., Mellanby R.J., 2015. Vitamin D status in cats with feline immunodeficiency virus. Veterinary Medicine and Science, 1, 72-78.
  • Townsend W, Jacobi S, Tai S, Kiupel M, Wise AG (2013). Ocular and Neural Distribution of Feline Herpesvirus-1 During Active and Latent Experimental Infection in Cats. BMC Veterinary Research, 9, 185.
  • Ulitsky A., Ananthakrishnan A.N., Naik A., Skaros S., Zadvornova Y., Binion D.G., Issa M., 2011. Vitamin D Deficiency in Patients with Inflammatory Bowel Disease. Journal of Parenteral and Enteral Nutrition, 35, 308-316.
  • Waldron J.L., Ashby H.L., Cornes M.P., Bechervaise J.., Razavi C., Thomas O.L., 2013. Vitamin D: a negative acute phase reactant. Journal of Clinical Pathology, 66, 620-622.
  • Weigler B.J., Guy J.S., Nasisse M.P., Hancock S.I., Sherry B., 1997. Effect of a live attenuated intranasal vaccine on latency and shedding of feline herpesvirus 1 in domestic cats. Archives of Virology, 142, 2389-400.
Toplam 32 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makalesi
Yazarlar

Ecem Duygu Yaz Demiroğlu Bu kişi benim 0000-0002-9423-0071

Mehmet Çağrı Karakurum 0000-0002-0767-883X

Proje Numarası 0567-YL-19
Yayımlanma Tarihi 26 Ağustos 2022
Gönderilme Tarihi 3 Şubat 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 10 Sayı: 2

Kaynak Göster

APA Yaz Demiroğlu, E. D., & Karakurum, M. Ç. (2022). Vitamin D Levels in Cats Infected with Feline Herpesvirus Type-1. Mehmet Akif Ersoy University Journal of Health Sciences Institute, 10(2), 103-107. https://doi.org/10.24998/maeusabed.1061278
AMA Yaz Demiroğlu ED, Karakurum MÇ. Vitamin D Levels in Cats Infected with Feline Herpesvirus Type-1. Mehmet Akif Ersoy University Journal of Health Sciences Institute. Ağustos 2022;10(2):103-107. doi:10.24998/maeusabed.1061278
Chicago Yaz Demiroğlu, Ecem Duygu, ve Mehmet Çağrı Karakurum. “Vitamin D Levels in Cats Infected With Feline Herpesvirus Type-1”. Mehmet Akif Ersoy University Journal of Health Sciences Institute 10, sy. 2 (Ağustos 2022): 103-7. https://doi.org/10.24998/maeusabed.1061278.
EndNote Yaz Demiroğlu ED, Karakurum MÇ (01 Ağustos 2022) Vitamin D Levels in Cats Infected with Feline Herpesvirus Type-1. Mehmet Akif Ersoy University Journal of Health Sciences Institute 10 2 103–107.
IEEE E. D. Yaz Demiroğlu ve M. Ç. Karakurum, “Vitamin D Levels in Cats Infected with Feline Herpesvirus Type-1”, Mehmet Akif Ersoy University Journal of Health Sciences Institute, c. 10, sy. 2, ss. 103–107, 2022, doi: 10.24998/maeusabed.1061278.
ISNAD Yaz Demiroğlu, Ecem Duygu - Karakurum, Mehmet Çağrı. “Vitamin D Levels in Cats Infected With Feline Herpesvirus Type-1”. Mehmet Akif Ersoy University Journal of Health Sciences Institute 10/2 (Ağustos 2022), 103-107. https://doi.org/10.24998/maeusabed.1061278.
JAMA Yaz Demiroğlu ED, Karakurum MÇ. Vitamin D Levels in Cats Infected with Feline Herpesvirus Type-1. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2022;10:103–107.
MLA Yaz Demiroğlu, Ecem Duygu ve Mehmet Çağrı Karakurum. “Vitamin D Levels in Cats Infected With Feline Herpesvirus Type-1”. Mehmet Akif Ersoy University Journal of Health Sciences Institute, c. 10, sy. 2, 2022, ss. 103-7, doi:10.24998/maeusabed.1061278.
Vancouver Yaz Demiroğlu ED, Karakurum MÇ. Vitamin D Levels in Cats Infected with Feline Herpesvirus Type-1. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2022;10(2):103-7.
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