Olgu Sunumu
Yıl 2020,
Cilt: 5 Sayı: 1, 23 - 27, 30.04.2020
Öz
In this case, pre/postoperatively
clinical and laboratory findings at the case of swelling of a long time mammary glands
in
22 month old Labrador Retriever breed bitch were presented Veterinary Faculty
Animal Hospital. In the anamnesis, it was learned that the size of the mammary
glands although it has been four months since oestrus symptoms and that
aglepriston was used to stay pregnant and terminate the pregnancy in the
previous oestrus. Physical examination revealed that the mammary glands were hyperplasic
from cranial to caudal and increased to normal. Palpation showed that the
mammary glands had a soft consistency and milk came from the mammary gland. Mammary
gland ultrasonography and lung radiography showed no pathological condition. Blood
serum prolactin and progesterone measurements were recorded. According to the
clinical and laboratory findings; it was diagnosed as pseudopregnancy and
treated with cabergoline and daisy tea. Repeated enlargements of the mammary
gland were observed in the same manner and durations during the sexual cycle
follow-ups performed for one year. No macroscopic mass or adverse condition was
observed in mammary glands during treatment and follow-up. In conclusion,
aglepriston, one of the exogenous agents used to terminate pregnancy at an
early age before complete sitting of hormonal development; Dogs caused
irregularities in their sexual cycles throughout their lives, suggesting that
suspected hormonal balance may predispose to various disorders in the future.
Anahtar Kelimeler
Kaynakça
- 1. Concannon PW, Yeager A, Frank D, Iyampillai A. Termination of pregnancy and induction of prematüre luteolysis by the antiprogestagen, mifepristone, in dogs. J. Reprod. Fertil. 1990; 88: 99-104.
- 2. Galac S, Kooistra HS, Butinar J, Bevers MM, Dieleman SJ, Voorhout G, et al. Termination of mid gestation pregnancy in bitches with aglepristone, P4 receptor antagonists. Theriogenology 2000; 53: 941-50.
- 3. Fieni F, Bruyas JF, Bttut, I. Clinical use of two protocols with a progesteron antogonist aglepristone (RU534) to induce parturation in bitches. J. Reprod. Fertil. 2001; 57: 237-42.
- 4. Wanke MM, Romagnoli S, Verstegen J, Concannon PW. Pharmacological approaches to pregnancy termination in dogs and cats including the use of prostaglandins, dopamine agonists and dexamethasone. In; Concannon PW, England G, Verstegen J, Linde-Forsberg C, editors. Recent Advances in Small Animal Reproduction. Ithaca; New York: 2002. p. 1-11.
- 5. Gobello C. Dopamine agonists, anti-progestins, anti-androgens, long-term-release GnRH agonists and anti-estrogens in canine reproduction; A review. Theriogenology 2006; 66: 1560-7.
- 6. Baulieu EE. Contragestion and other clinical applications of RU486, and antiprogesterone at the receptor. Science 1989; 245: 1351-7.
- 7. Hoffmann B, Schuler G. Receptor blockers-general aspects with respect to their use in domestic animal reproduction. Anim Reprod Sci 2000; 60: 295-312.
- 8. Johnston SD, Root Kustritz MV, Olson PNS. Canine and feline theriogenology. 1st ed. Philadelphia: Saunders; 2001.
- 9. Concannon PW, Mccan JP, Temple M. Biology and endocrinology of ovulation, pregnancy and parturition in the dog. J. Reprod. Fertil 1989; 39: 3-25.
- 10. Olson PN, Nett TM, Bowen RA, Sawyer HR, Niswender GD. Endocrine regulation of the corpus luteum of the bitch as a potential target for altering fertility. J. Reprod. Fertil. 1989; 39: 27-40.
- 11. Fieni F, Tainturier D, Bruya JF. Etude clinique d.une anti-hormone pour provoquer l.avortement chez la chienne. Rec Med Vet 1996; 172: 359-67.
- 12. Pettersson CH, Tidholm A. Safety and efficacy of mid-term pregnancy termination using aglepristone in dogs. J Small Anim Pract 2009; 50: 120-3.
- 13. Gogny A, Fieni F. Aglepristone; A review on its clinical use in animals. Theriogenology 2016; 85(4): 555-66.
- 14. Corrada Y, Garcia P, de la Sota PE, Huzman M, Landoni MF, Gobello C. Decrease of body temperature after aglepristone treatment in bitches. Animal Reproduction Science 2005; 87(3-4): 295-9.
- 15. Galac S, Kooistra HS, Dieleman SJ, Cestnik V, Okkens AC. Effects of aglepristone, a progesterone receptor antagonist, administered during the early luteal phase in non-pregnant bitches. Theriogenology 2004; 62: 494-500.
- 16. Kanca H, Karakaş K. Effectiveness of Aglepristone at Lower-Than-Standard Doses in Prevention of Pregnancy in Mismated Bitches. Kafkas Univ Vet Fak Derg 2012; 18 (3): 517-21.
- 17. Baan M, Taverne MM, Kooistra HS, de Gier J, Dieleman SJ, Okkens AJ. Induction of parturition in the bitch with the progesterone-receptor blocker agle'pristone. Theriogenology 2005; 63: 1958-72.
- 18. Trasch K, Wehrend A, Bostedt H. Follow-up examinations of bitches after conservative treatment of pyometra with the antigestagen aglepristone. J Vet Med A Physiol Pathol Clin Med 2003; 50: 375-9.
- 19. Fieni F. Clinical evaluation of the use of aglepristone, with or without cloprostenol, to treat cystic endometrial hyperplasia-pyometra complex in bitches. Theriogenology 2006; 66: 1550-6.
- 20. Bhatti SF, Rao NA, Okkens AC, Mol JA, Duchateau L, Ducatelle R, van den Ingh GAM, et al. Role of progestin-induced mammary-derived growth hormone in the pathogenesis of cystic endometrial hyperplasia in the bitch. Domest Anim Endocrinol 2007; 33: 294-312.
- 21. Wehrend A, Hospes R, Gruber AD. Treatment of feline mammary fibroadenomatous hyperplasia with a progesterone-antagonist. Vet Rec 2001; 148: 346-7.
- 22. Lee WM, Kooistra HS, Mol JA, Dieleman SJ, Okkens AC. Ovariectomy during the luteal phase influences secretion of prolactin, growth hormone, and insulin-like growth factor-I in the bitch. Theriogenology 2006; 66: 484-90.
- 23. Beijerink NJ, Bhatti SF, Okkens AC, Dieleman SJ, Mol JA, Duchateau L, et al. Adenohypophyseal function in bitches treated with medroxyprogesterone acetate. Domest Anim Endocrinol 2007; 32: 63-78.
- 24. Aksoy OA. Aglepriston Ve Aglepriston-Cabergolin Kombinasyonuyla Köpekte Abortun İndüksiyonu, Doktora tezi, T. C. Ankara Üniversitesi Sağlık Bilimleri Enstitüsü 2007.
- 25. Schafer-Somi S, Aksoy OA, Beceriklisoy HB, Einspanier A, Hoppen HO, Aslan S. Repeated induction of abortion in bitches and the effect on plasma concentrations of relaxin, progesterone and estradiol-17β. Theriogenology 2007; 68: 889-95.
- 26. Concannon PW. Reproductive cycles of the domestic bitch. Anim Reprod Sci. 2011; 124: 200–10.
- 27. De Gier J, Kooistra HS, Djajadiningrat-Laanen SC, Dieleman SJ, Okkens AC. Temporal relations between plasma concentrations of luteinizing hormone, follicle-stimulating hormone, estradiol-17beta, progesterone, prolactin, and alpha-melanocyte-stimulating hormone during the follicular, ovulatory, and early luteal phase in the bitch. Theriogenology. 2006; 65: 1346-59.
- 28. O'Connor CL, Schweizer C, Gradil C, Schlafer D, Lopate C, Prociuk U, et al. Trisomy-X with estrous cycle anomalies in two female dogs. Theriogenology. 2011; 76: 374-80.
Yıl 2020,
Cilt: 5 Sayı: 1, 23 - 27, 30.04.2020
Öz
Kaynakça
- 1. Concannon PW, Yeager A, Frank D, Iyampillai A. Termination of pregnancy and induction of prematüre luteolysis by the antiprogestagen, mifepristone, in dogs. J. Reprod. Fertil. 1990; 88: 99-104.
- 2. Galac S, Kooistra HS, Butinar J, Bevers MM, Dieleman SJ, Voorhout G, et al. Termination of mid gestation pregnancy in bitches with aglepristone, P4 receptor antagonists. Theriogenology 2000; 53: 941-50.
- 3. Fieni F, Bruyas JF, Bttut, I. Clinical use of two protocols with a progesteron antogonist aglepristone (RU534) to induce parturation in bitches. J. Reprod. Fertil. 2001; 57: 237-42.
- 4. Wanke MM, Romagnoli S, Verstegen J, Concannon PW. Pharmacological approaches to pregnancy termination in dogs and cats including the use of prostaglandins, dopamine agonists and dexamethasone. In; Concannon PW, England G, Verstegen J, Linde-Forsberg C, editors. Recent Advances in Small Animal Reproduction. Ithaca; New York: 2002. p. 1-11.
- 5. Gobello C. Dopamine agonists, anti-progestins, anti-androgens, long-term-release GnRH agonists and anti-estrogens in canine reproduction; A review. Theriogenology 2006; 66: 1560-7.
- 6. Baulieu EE. Contragestion and other clinical applications of RU486, and antiprogesterone at the receptor. Science 1989; 245: 1351-7.
- 7. Hoffmann B, Schuler G. Receptor blockers-general aspects with respect to their use in domestic animal reproduction. Anim Reprod Sci 2000; 60: 295-312.
- 8. Johnston SD, Root Kustritz MV, Olson PNS. Canine and feline theriogenology. 1st ed. Philadelphia: Saunders; 2001.
- 9. Concannon PW, Mccan JP, Temple M. Biology and endocrinology of ovulation, pregnancy and parturition in the dog. J. Reprod. Fertil 1989; 39: 3-25.
- 10. Olson PN, Nett TM, Bowen RA, Sawyer HR, Niswender GD. Endocrine regulation of the corpus luteum of the bitch as a potential target for altering fertility. J. Reprod. Fertil. 1989; 39: 27-40.
- 11. Fieni F, Tainturier D, Bruya JF. Etude clinique d.une anti-hormone pour provoquer l.avortement chez la chienne. Rec Med Vet 1996; 172: 359-67.
- 12. Pettersson CH, Tidholm A. Safety and efficacy of mid-term pregnancy termination using aglepristone in dogs. J Small Anim Pract 2009; 50: 120-3.
- 13. Gogny A, Fieni F. Aglepristone; A review on its clinical use in animals. Theriogenology 2016; 85(4): 555-66.
- 14. Corrada Y, Garcia P, de la Sota PE, Huzman M, Landoni MF, Gobello C. Decrease of body temperature after aglepristone treatment in bitches. Animal Reproduction Science 2005; 87(3-4): 295-9.
- 15. Galac S, Kooistra HS, Dieleman SJ, Cestnik V, Okkens AC. Effects of aglepristone, a progesterone receptor antagonist, administered during the early luteal phase in non-pregnant bitches. Theriogenology 2004; 62: 494-500.
- 16. Kanca H, Karakaş K. Effectiveness of Aglepristone at Lower-Than-Standard Doses in Prevention of Pregnancy in Mismated Bitches. Kafkas Univ Vet Fak Derg 2012; 18 (3): 517-21.
- 17. Baan M, Taverne MM, Kooistra HS, de Gier J, Dieleman SJ, Okkens AJ. Induction of parturition in the bitch with the progesterone-receptor blocker agle'pristone. Theriogenology 2005; 63: 1958-72.
- 18. Trasch K, Wehrend A, Bostedt H. Follow-up examinations of bitches after conservative treatment of pyometra with the antigestagen aglepristone. J Vet Med A Physiol Pathol Clin Med 2003; 50: 375-9.
- 19. Fieni F. Clinical evaluation of the use of aglepristone, with or without cloprostenol, to treat cystic endometrial hyperplasia-pyometra complex in bitches. Theriogenology 2006; 66: 1550-6.
- 20. Bhatti SF, Rao NA, Okkens AC, Mol JA, Duchateau L, Ducatelle R, van den Ingh GAM, et al. Role of progestin-induced mammary-derived growth hormone in the pathogenesis of cystic endometrial hyperplasia in the bitch. Domest Anim Endocrinol 2007; 33: 294-312.
- 21. Wehrend A, Hospes R, Gruber AD. Treatment of feline mammary fibroadenomatous hyperplasia with a progesterone-antagonist. Vet Rec 2001; 148: 346-7.
- 22. Lee WM, Kooistra HS, Mol JA, Dieleman SJ, Okkens AC. Ovariectomy during the luteal phase influences secretion of prolactin, growth hormone, and insulin-like growth factor-I in the bitch. Theriogenology 2006; 66: 484-90.
- 23. Beijerink NJ, Bhatti SF, Okkens AC, Dieleman SJ, Mol JA, Duchateau L, et al. Adenohypophyseal function in bitches treated with medroxyprogesterone acetate. Domest Anim Endocrinol 2007; 32: 63-78.
- 24. Aksoy OA. Aglepriston Ve Aglepriston-Cabergolin Kombinasyonuyla Köpekte Abortun İndüksiyonu, Doktora tezi, T. C. Ankara Üniversitesi Sağlık Bilimleri Enstitüsü 2007.
- 25. Schafer-Somi S, Aksoy OA, Beceriklisoy HB, Einspanier A, Hoppen HO, Aslan S. Repeated induction of abortion in bitches and the effect on plasma concentrations of relaxin, progesterone and estradiol-17β. Theriogenology 2007; 68: 889-95.
- 26. Concannon PW. Reproductive cycles of the domestic bitch. Anim Reprod Sci. 2011; 124: 200–10.
- 27. De Gier J, Kooistra HS, Djajadiningrat-Laanen SC, Dieleman SJ, Okkens AC. Temporal relations between plasma concentrations of luteinizing hormone, follicle-stimulating hormone, estradiol-17beta, progesterone, prolactin, and alpha-melanocyte-stimulating hormone during the follicular, ovulatory, and early luteal phase in the bitch. Theriogenology. 2006; 65: 1346-59.
- 28. O'Connor CL, Schweizer C, Gradil C, Schlafer D, Lopate C, Prociuk U, et al. Trisomy-X with estrous cycle anomalies in two female dogs. Theriogenology. 2011; 76: 374-80.
Toplam 28 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Olgu Sunumları |
| Yazarlar | |
| Yayımlanma Tarihi | 30 Nisan 2020 |
| Gönderilme Tarihi | 8 Eylül 2019 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 5 Sayı: 1 |
