Öz
Lipase is a hydrolytic enzyme and commonly used for the diagnosis of pancreatitis with amylase. Except for pancreatitis, lipase is elevated in many clinical conditions such as hepatobiliary disorders, bowel diseases, malignancies, renal impairment. Celiac disease (CD) should be considered as one of the causes. In patients with CD, the frequency of pancreatic hyperenzymemia and possible pathophysiological mechanisms are not well studied. To date, several mechanisms explaining pancreatic hyperenzymemia in CD are reported. Malnutrition, disease bowel induced pancreatic dysfunction, autoimmune pancreatic inflammation, and macroenzymemia are the main ones. Herein, we report a patient with newly diagnosed CD, representing markedly elevated serum lipase level with normal amylase.
Anahtar Kelimeler
celiac disease hyperlipasemia macrolipasemia pancreatic hyperenzymemia
Destekleyen Kurum
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Proje Numarası
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Teşekkür
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Kaynakça
- 1. Frulloni L, Patrizi F, Bernardoni L, Cavallini G. Pancreatic hyperenzymemia: Clinical significance and diagnostic approach.JOP. 2005 ;6:536-51.
- 2. Holmes GK. Non-malignant complications of coeliac disease. Acta Paediatr Suppl. 1996;412:68-75.
- 3. Carroccio A, Di Prima L, Scalici C, Soresi M, CefalÙ AB, Noto D, et al. Unexplained elevated serum pancreatic enzymes: A reason to suspect celiac disease. Clin Gastroenterol Hepatol. 2006;4:455–9.
- 4. Hameed AM, Lam VWT, Pleass HC. Significant elevations of serum lipase not caused by pancreatitis: A systematic review. Hpb. 2015;17:99–112.
- 5. Migliori M, Galassi E, Gullo L. Search for celiac disease in subjects with asymptomatic pancreatic hyperenzymemia. Pancreas. 2011;40:979-81.
- 6. Freeman HJ. Celiac-associated pancreatic disease. Ann Gastroenterol. 2016;29:241-2.
- 7. Lauret E, Rodrigo L. Celiac disease and autoimmune-associated conditions. Biomed Res Int. 2013;2013:127589
- 8. Di Sabatino A, Corazza GR. Coeliac disease. Lancet. 2009;373:1480-93.
- 9. Rabsztyn A, Green PH, Berti I, Fasano A, Perman JA, Horvath K. Macroamylasemia in patients with celiac disease. Am J Gastroenterol. 2001;96:1096
- 10. Garcia‐Gonzalez M, Defarges‐Pons V, Monescillo A, Hernandez F, Cano‐Ruiz A. Macrolipasemia and celiac disease. Am J Gastroenterol. 1995;90:2233-4.
Öz
Proje Numarası
-
Kaynakça
- 1. Frulloni L, Patrizi F, Bernardoni L, Cavallini G. Pancreatic hyperenzymemia: Clinical significance and diagnostic approach.JOP. 2005 ;6:536-51.
- 2. Holmes GK. Non-malignant complications of coeliac disease. Acta Paediatr Suppl. 1996;412:68-75.
- 3. Carroccio A, Di Prima L, Scalici C, Soresi M, CefalÙ AB, Noto D, et al. Unexplained elevated serum pancreatic enzymes: A reason to suspect celiac disease. Clin Gastroenterol Hepatol. 2006;4:455–9.
- 4. Hameed AM, Lam VWT, Pleass HC. Significant elevations of serum lipase not caused by pancreatitis: A systematic review. Hpb. 2015;17:99–112.
- 5. Migliori M, Galassi E, Gullo L. Search for celiac disease in subjects with asymptomatic pancreatic hyperenzymemia. Pancreas. 2011;40:979-81.
- 6. Freeman HJ. Celiac-associated pancreatic disease. Ann Gastroenterol. 2016;29:241-2.
- 7. Lauret E, Rodrigo L. Celiac disease and autoimmune-associated conditions. Biomed Res Int. 2013;2013:127589
- 8. Di Sabatino A, Corazza GR. Coeliac disease. Lancet. 2009;373:1480-93.
- 9. Rabsztyn A, Green PH, Berti I, Fasano A, Perman JA, Horvath K. Macroamylasemia in patients with celiac disease. Am J Gastroenterol. 2001;96:1096
- 10. Garcia‐Gonzalez M, Defarges‐Pons V, Monescillo A, Hernandez F, Cano‐Ruiz A. Macrolipasemia and celiac disease. Am J Gastroenterol. 1995;90:2233-4.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | İç Hastalıkları |
| Bölüm | Case Reports |
| Yazarlar | |
| Proje Numarası | - |
| Yayımlanma Tarihi | 29 Nisan 2021 |
| Gönderilme Tarihi | 22 Ekim 2020 |
| Kabul Tarihi | 14 Ocak 2021 |
| Yayımlandığı Sayı | Yıl 2021 Cilt: 3 Sayı: 2 |
