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Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume

Yıl 2021, Cilt: 5 Sayı: 3, 312 - 316, 30.12.2021

Veysel Barış Turhan Abdulkadir Ünsal Mutlu Şahin Hakan Buluş

https://doi.org/10.25048/tudod.1004760

Öz

Aim: Obesity is one of the most common diseases, The main goal in bariatric surgeries is to reduce the gastric volume. Also, studies
have linked reduced abdominal volume and weight loss. Our aim in this study is to investigate intraoperatively administered hyoscine
butylbromide(HBB) on the removed gastric volüme(RGV).
Material and Methods: The study, which was planned as a retrospective cohort study, included 67 patients who underwent laparoscopic
sleeve gastrectomy (LSG). HBB at a dose of 20 mg was given to 32 patients preoperatively(Group II). A similar procedure was applied
to 35 patients in the control group(Group I), but HBB was not given. Demographic characteristics, body mass indexes, and laboratory
values of the patients were recorded. Weight loss and changes in BMI were recorded at the first and sixth month controls. Data were
analyzed for normality of distribution with the Shapiro-Wilk test. Non-parametric values for general differences between groups were
analyzed with the Mann-Whitney U test and parametric values were analyzed with Student t-test .
Results: In Group II, the removed gastric volume was greater. In the first and sixth month BMI, there was a significant difference
between the groups. Group II lost more weight statistically, and as a result, their BMI decreased significantly.
Conclusion: It was observed that inexpensive and easily accessible HBB increased the removed gastric volume in bariatric surgery and
contributed to weight loss.

Anahtar Kelimeler

sleeve gastrectomy gastric volume hyoscine butylbromide

Teşekkür

Thanks to AME Editor from American Manuscript Editors for editing the manuscript.

Kaynakça

  • Melissas, J et al. Sleeve gastrectomy—a restrictive procedure?. Obes Surg , 2007: 17(1), 57.
  • Marceau, P. et al. Biliopancreatic diversion with a new type of gastrectomy. Obes Surg 1993: 3(1), 29-35.
  • Roa, P. E. et al. Laparoscopic sleeve gastrectomy as treatment for morbid obesity: technique and short-term outcome. Obes Surg , 2006: 16(10), 1323-1326.
  • Braghetto, I. et al. Laparoscopic sleeve gastrectomy: surgical technique, indications and clinical results. Obes Surg , 2007: 17(11), 1442-1450.
  • Ariyasu, H. et al. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. The Journal of Clinical Endocrinology & Metabolism, 2001: 86(10), 4753-4758.
  • Gutzeit, A. et al. Evaluation of the anti-peristaltic effect of glucagon and hyoscine on the small bowel: comparison of intravenous and intramuscular drug administration. European radiology, 2012: 22(6), 1186-1194.
  • Staritz M. Pharmacology of the sphincter of Oddi. Endoscopy 1988;20 Suppl 1:171–4.
  • East, J. E. et al. Mechanisms of hyoscine butylbromide to improve adenoma detection: A case-control study of surface visualization at simulated colonoscope withdrawal. Endosc Int Open. 2015;3(6):E636-E641.
  • Cottam, D. et al. Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity. Surg Endosc 2006; 20: 859-63.
  • Regan, J. P. et al. Early experience with two-stage laparoscopic Roux-en-Y gastric bypass as an alternative in the super-super obese patient. Obes Surg 2003; 13: 861-4.
  • Stacher G. et al. Effects of oral cyclotropium bromide, hyoscine N-butylbromide and placebo on gastric emptying and antral motor activity in healthy man. Gut. 1984 May;25(5):485-90.
  • Yoshikawa I. et al. Comparison of glucagons and scopolamine butylbromide as premedications for colonoscopy in unsedated patients Dis. Colon Rectum 2006: 49 1393–8
  • Weiner, R. A. et al. Laparoscopic Sleeve Gastrectomy — Influence of Sleeve Size and Resected Gastric Volume. Obes Surg 2007: 17, 1297
  • Deguines, J. B. et al. Is the residual gastric volume after laparoscopic sleeve gastrectomy an objective criterion for adapting the treatment strategy after failure? Surgery for Obesity and Related Diseases 2013: 9.5 660-666.
  • Sista, F. et al. Effect of resected gastric volume on ghrelin and GLP-1 plasma levels: a prospective study. Journal of Gastrointestinal Surgery, 2016: 20(12), 1931-1941.
  • Du, X. et al. Resected gastric volume has no influence on early weight loss after laparoscopic sleeve gastrectomy. Surgery for Obesity and Related Diseases, 2018: 14(2), 129-135.

Laparoskopik Sleeve Gastrektomi Sırasında Kullanılan Hyoscine-Butylbromide, Çıkarılan Mide Hacmini Artırır

Yıl 2021, Cilt: 5 Sayı: 3, 312 - 316, 30.12.2021

Veysel Barış Turhan Abdulkadir Ünsal Mutlu Şahin Hakan Buluş

https://doi.org/10.25048/tudod.1004760

Öz

Amaç: Obezite en sık görülen hastalıklardan biridir. Obezite ameliyatlarında temel amaç mide hacmini azaltmaktır. Ayrıca çalışmalar, karın
hacminin azalması ve kilo kaybını ilişkilendirmiştir. Bu çalışmada amacımız, intraoperatif uygulanan hyoscine butylbromide(HBB)'in
çıkarılan mide hacmi üzerine etkisinin araştırılmasıdır.
Gereç ve Yöntemler: Retrospektif cohort çalışması olarak planlanan çalışmaya laparoskopik sleeve gastrektomi (LSG) uygulanan 67
hasta dahil edildi. Ameliyat öncesi 32 hastaya 20 mg HBB verildi(grup II). Kontrol grubundaki 35 hastaya benzer bir işlem uygulandı
ancak HBB verilmedi(grup I). Hastaların demografik özellikleri, vücut kütle indeksleri ve laboratuvar değerleri kaydedildi. Kilo kaybı
ve vücut kütle indeksleri (VKİ)ndeki değişiklikler birinci ve altıncı ay kontrollerinde kaydedildi. Veriler, Shapiro-Wilk testi ile dağılımın
normalliği için analiz edildi. Gruplar arasında genel farklılıklar, parametrik olmayan değerler için Mann-Whitney U testi ile, parametrik
değerler ise Student-t testi ile analiz edildi.
Bulgular: Grup II'de çıkarılan mide hacmi daha fazlaydı. Birinci ve altıncı ay VKİ 'lerinde gruplar arasında anlamlı fark vardı. Grup II,
istatistiksel olarak daha fazla kilo verdi ve sonuç olarak VKİ'leri önemli ölçüde azalmıştı.
Sonuç: Ucuz ve kolay ulaşılabilir HBB'nin obezite cerrahisinde çıkarılan mide hacmini arttırdığı ve kilo kaybına katkı sağladığı görüldü

Anahtar Kelimeler

Sleeve gastrektomi hiyosin butilbromid mide hacmi

Kaynakça

  • Melissas, J et al. Sleeve gastrectomy—a restrictive procedure?. Obes Surg , 2007: 17(1), 57.
  • Marceau, P. et al. Biliopancreatic diversion with a new type of gastrectomy. Obes Surg 1993: 3(1), 29-35.
  • Roa, P. E. et al. Laparoscopic sleeve gastrectomy as treatment for morbid obesity: technique and short-term outcome. Obes Surg , 2006: 16(10), 1323-1326.
  • Braghetto, I. et al. Laparoscopic sleeve gastrectomy: surgical technique, indications and clinical results. Obes Surg , 2007: 17(11), 1442-1450.
  • Ariyasu, H. et al. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. The Journal of Clinical Endocrinology & Metabolism, 2001: 86(10), 4753-4758.
  • Gutzeit, A. et al. Evaluation of the anti-peristaltic effect of glucagon and hyoscine on the small bowel: comparison of intravenous and intramuscular drug administration. European radiology, 2012: 22(6), 1186-1194.
  • Staritz M. Pharmacology of the sphincter of Oddi. Endoscopy 1988;20 Suppl 1:171–4.
  • East, J. E. et al. Mechanisms of hyoscine butylbromide to improve adenoma detection: A case-control study of surface visualization at simulated colonoscope withdrawal. Endosc Int Open. 2015;3(6):E636-E641.
  • Cottam, D. et al. Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity. Surg Endosc 2006; 20: 859-63.
  • Regan, J. P. et al. Early experience with two-stage laparoscopic Roux-en-Y gastric bypass as an alternative in the super-super obese patient. Obes Surg 2003; 13: 861-4.
  • Stacher G. et al. Effects of oral cyclotropium bromide, hyoscine N-butylbromide and placebo on gastric emptying and antral motor activity in healthy man. Gut. 1984 May;25(5):485-90.
  • Yoshikawa I. et al. Comparison of glucagons and scopolamine butylbromide as premedications for colonoscopy in unsedated patients Dis. Colon Rectum 2006: 49 1393–8
  • Weiner, R. A. et al. Laparoscopic Sleeve Gastrectomy — Influence of Sleeve Size and Resected Gastric Volume. Obes Surg 2007: 17, 1297
  • Deguines, J. B. et al. Is the residual gastric volume after laparoscopic sleeve gastrectomy an objective criterion for adapting the treatment strategy after failure? Surgery for Obesity and Related Diseases 2013: 9.5 660-666.
  • Sista, F. et al. Effect of resected gastric volume on ghrelin and GLP-1 plasma levels: a prospective study. Journal of Gastrointestinal Surgery, 2016: 20(12), 1931-1941.
  • Du, X. et al. Resected gastric volume has no influence on early weight loss after laparoscopic sleeve gastrectomy. Surgery for Obesity and Related Diseases, 2018: 14(2), 129-135.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makalesi
Yazarlar

Veysel Barış Turhan 0000-0001-5093-4993

Abdulkadir Ünsal 0000-0002-7989-4232

Mutlu Şahin 0000-0003-0371-4095

Hakan Buluş 0000-0003-2555-4707

Yayımlanma Tarihi 30 Aralık 2021
Kabul Tarihi 9 Aralık 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 5 Sayı: 3

Kaynak Göster

APA Turhan, V. B., Ünsal, A., Şahin, M., Buluş, H. (2021). Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume. Türkiye Diyabet Ve Obezite Dergisi, 5(3), 312-316. https://doi.org/10.25048/tudod.1004760
AMA Turhan VB, Ünsal A, Şahin M, Buluş H. Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume. Turk J Diab Obes. Aralık 2021;5(3):312-316. doi:10.25048/tudod.1004760
Chicago Turhan, Veysel Barış, Abdulkadir Ünsal, Mutlu Şahin, ve Hakan Buluş. “Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume”. Türkiye Diyabet Ve Obezite Dergisi 5, sy. 3 (Aralık 2021): 312-16. https://doi.org/10.25048/tudod.1004760.
EndNote Turhan VB, Ünsal A, Şahin M, Buluş H (01 Aralık 2021) Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume. Türkiye Diyabet ve Obezite Dergisi 5 3 312–316.
IEEE V. B. Turhan, A. Ünsal, M. Şahin, ve H. Buluş, “Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume”, Turk J Diab Obes, c. 5, sy. 3, ss. 312–316, 2021, doi: 10.25048/tudod.1004760.
ISNAD Turhan, Veysel Barış vd. “Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume”. Türkiye Diyabet ve Obezite Dergisi 5/3 (Aralık 2021), 312-316. https://doi.org/10.25048/tudod.1004760.
JAMA Turhan VB, Ünsal A, Şahin M, Buluş H. Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume. Turk J Diab Obes. 2021;5:312–316.
MLA Turhan, Veysel Barış vd. “Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume”. Türkiye Diyabet Ve Obezite Dergisi, c. 5, sy. 3, 2021, ss. 312-6, doi:10.25048/tudod.1004760.
Vancouver Turhan VB, Ünsal A, Şahin M, Buluş H. Hyoscine-Butylbromide Used During Laparoscopic Sleeve Gastrectomy Increases Removed Gastric Volume. Turk J Diab Obes. 2021;5(3):312-6.
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