Öz
Bir Simental inekte rektal fibromatozis
Özet: Bu
olayda 4 yaşlı Simental ırkı inekte rektum bölgesinde gözlenen çok sayıdaki tümöral
kitlelerden dolayı rektal muayeneyi zorlaştıran ve operasyonuna karar verilen
fibromatozis olgusunun klinik ve patolojik yönden incelenmesi amaçlandı. Hayvanda
doğumu izleyen dönemde rektal muayene yapılmak istendiğinde rektum çevresinde zamanla
sayı ve hacimleri artan kitleler gözlendi. En büyüğü 6,5 cm çapında yuvarlak ve 4x3x1,4cm
büyüklüğünde oval, çeşitli büyüklükte 14 adet katı esnek kıvamda, beyaz renkli kitlelere
rastlandı. Kitlelerin bazıları deri ve çoğunlukla mukoza ile kaplı olduğu
dikkati çekti. %10’luk tamponlu formaldehit ile tespit edilerek parafine gömülen
ve 5 µm kalınlığında kesitler alınan dokular, Hematoksilen-Eosin (H-E) ve Van
Gieson ile ayrıca immunohistokimyasal (İHK) olarak sitokeratin ve vimentin ile
boyandı. H-E kesitli dokulardaki tümöral kitlenin tipik anafor tarzında
yerleşmiş fibroblast ve fibrositlerden oluştuğu, yapılan İHK boyamada ise
vimentin pozitif ve sitokeratin negatif olarak gözlendi. Bu olgudaki gözlenen
makroskobik, mikroskobik ve İHK’sal bulgular kaudal rektumda fibromatozis
olgusu ile uyumlu bulunmuştur.
Anahtar kelimeler:
İnek, rektum, fibroma
Rectal
fibromatosis in a Simmental cow.
Abstract:In this case, it was aimed to investigate the clinical
and pathological aspects of fibromatosis which make difficult rectal
examination due to multiple tumoral masses observed in a 4-year-old
Simmental–breed at rectum. Period of after the birth, the masses were seen
around the rectal area of the cow when rectal examination was carried out. The
number and volume of masses increased with time.The shapes of masses were round
and oval and the largest size were 6.5 cm in diameter and 4 x 3 x 1.4 cm
respectively. Totally 14 masses, covered with skin and mucosal membrane were
found. Cut surface were whitish colored and solid-flexible in consistency. The
tissues were fixed with 10% buffered formaldehyde and embedded in paraffin and
sections with a thickness of 5 μm were stained with hematoxylen-eosin (H&E)
and Van Gieson and immunohistochemical (IHC) with cytokeratin and
vimentin.Tumor tissue in H&E sections consisted of fibroblasts and
fibrocytes located in the typical herringbonepattern. Tumoral cells were vimentin-positive and
cytokeratin-negative in IHC staining.Macroscopic, microscopic and IHC findings,
in this case, were found to be consistent with the presence of fibromatosis in
the caudal rectum.
Key words: Cow, rectum, fibroma
Kaynakça
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Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Olgu sunumları |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Haziran 2018 |
| Kabul Tarihi | 26 Mart 2018 |
| Yayımlandığı Sayı | Yıl 2018 Cilt: 37 Sayı: 1 |