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Diz Osteoartritte Enjeksiyon Yöntemleri

Yıl 2023, Cilt: 3 Sayı: 3, 608 - 622, 21.12.2023

Sevde Nur Aktaş Metehan Yana

Öz

Osteoartrit özellikle ileri yaş ve artan obezite sonucu popülasyonda yaygınlığı artan romatizmal bir hastalıktır. “Osteoarthritis Research Society International” (OARSI); osteoartriti, hareketli eklemleri etkileyen, travmaların gelişimini hızlandırdığı doğal immunitenin proinflamatuar süreçlerini içeren uygun olmayan onarım cevabı sonucu oluşan hücre stresi ve hücre dışı matriks dejenerasyonu olarak tanımlamıştır. Osteoartrit (OA) eklem kıkırdağında bozulma, kemiklerde düzensiz büyüme, sinovyal çoğalma ve dejenerasyonla ilerler. Bireyde şiddetli ağrı ve hareket kısıtlılığına yol açan osteoartrit sıklıkla dizler, kalça, omurga ve ellerde distal interfalengial, proksimal interfalengial eklemler, birinci karpometakarpal eklemlerde görülür. İleri yaşla birlikte OA insidansı giderek artar. Dünya genelinde 60 yaş üzeri erkeklerin %9,6’sı kadınların ise %18’inde semptomatik OA görülmektedir. Tanı klinik ve radyolojik bulgular ile konulmaktadır. OA tedavi seçenekleri farmakolojik, non-farmakolojik, intraartiküler ve cerrrahi tedavileri içerir. Günümüzdeki tedaviler ile amaç, hastanın ağrısını ve sabah tutukluğunu azaltmak, eklem hareket açıklığı ve kas gücünü korumak ya da yeniden kazandırmak, günlük yaşam aktivitelerindeki bağımlılığı azaltmaktır. Tedavi fizik tedavi modalitelerini, ortezleri, farmakolojik tedavileri ve cerrahi girişimleri kapsar. Semptomatik ve oral farmakolojik tedavilere cevap alınamayan hastalarda intraartiküler enjeksiyonlardan faydalanılmaktadır. Bu derleme çalışmasında gün geçtikçe kullanımı artan kortikosteroid, hyalüronik asit, kolajen, PRP, proloterapi, kök hücre yöntemleri ve bu yöntemlerin OA’lı hastalar üzerindeki etkilerinin incelenmesi amaçlanmaktadır.

Anahtar Kelimeler

Diz osteoartrit Enjeksiyon Enjeksiyon yöntemleri.

Kaynakça

  • Aksu, K. (2003). In Klinik Romatoloji El Kitabı, Doğanavşargil, E., Gümüşdiş, G., (Ed.), Osteoartrit, (1-10). 1.Baskı. İzmir: Güven Kitabevi.
  • Aletto, C., Oliva, F., & Maffulli, N. (2022). Knee intra-articular administration of stromal vascular fraction obtained from adipose tissue: A systematic review. Journal of Clinical Orthopaedics and Trauma, 25, 101773. https://doi.org/10.1016/j.jcot.2022.101773
  • Altman, R., Asch, E, Bloch, D., Bole, G., Boreinstein, D, Brandt K., Christy, W., Cooke, T.D., Greenwald, R., Hochberg, M. (1986). Development of criteria for classification and reporting of osteoarthritis of knee. Diagnostic and Therapeutic Criteria Committee of American Rheumatism Association. Arthritis Rheum, 29, 1039-1049. https://doi.org/10.1002/art.1780290816
  • Andia, I., & Maffulli, N. (2013). Platelet-rich plasma for managing pain and inflammation in osteoarthritis. Nature Reviews. Rheumatology, 9(12), 721–730. https://doi.org/10.1038/nrrheum.2013.141
  • Atay, T., Aslan, A., Baydar, M.L., Ceylan, B., Baykal, B., Kırdemir, V. (2008). Gonartrozlu hastalarda artroskopik debridman sonrası viskosüplemantasyon uygulamalarının karşılaştırılması. Acta Orthop et Traumatol Turc, 42, 228-233. https://doi.org/10.3944/aott.2008.228
  • Bakilan, F., Armagan, O., Ozgen, M., Tascioglu, F., Bolluk, O., & Alatas, O. (2016). Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial. The Eurasian Journal of Medicine, 48(2), 95–101. https://doi.org/10.5152/eurasianjmed.2015.15030
  • Bannuru, R.R., Osani, M.C., Vaysbrot, E.E, Arden, N.K., Bennell, K., Bierma-Zeinstra SMA, Kraus, V. B., Lohmander, L. S., Abbott, J. H., Bhandari, M., Blanco, F. J., Espinosa, R., Haugen, I. K., Lin, J., Mandl, L. A., Moilanen, E., Nakamura, N., Snyder-Mackler, L., Trojian, T., Underwood, M., … McAlindon, T. E. (2019). OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis Cartilage, 27(11), 1578-1589. https://doi.org/10.1016/j.joca.2019.06.011
  • Bayrak, A., Bayrak, S. K., Duramaz, A., Sahan, C., Büyükhatipoğlu, A., & Aslantaş, F. Ç. (2018). Evre 3-4 Gonartrozlu Hastalarda Diz İçi Steroid Enjeksiyonun Etkinliği. Bakırköy Tıp Dergisi, 14(4), 372-376. Erişim: https://search.trdizin.gov.tr/yayin/detay/315206
  • Borja-Flores, A., Macías-Hernández, S. I., Hernández-Molina, G., Perez-Ortiz, A., Reyes-Martínez, E., Belzazar-Castillo de la Torre, J., Ávila-Jiménez, L., Vázquez-Bello, M. C., León-Mazón, M. A., Furuzawa-Carballeda, J., Torres-Villalobos, G., Romero-Hernández, F., Albavera-Hernández, C., Pérez-Correa, J., & Castro-Rocha, H. A. (2020). Long-Term Effectiveness of Polymerized-Type I Collagen Intra-Articular Injections in Patients with Symptomatic Knee Osteoarthritis: Clinical and Radiographic Evaluation in a Cohort Study. Advances in Orthopedics. https://doi.org/10.1155/2020/9398274
  • Brzusek, D., Petron D. (2008). Treating knee osteoarthritis with intra-articular hyaluronans. Curr Med Res Opin, 24(12), 3307-3322. https://doi.org/10.1185/03007990802490124
  • Chapple, C.M, Nicholson, H, Baxter, G.D, Abbott, JH. (2011). Patient characteristics that predict progression of knee osteoarthritis: a systematic review of prognostic studies. Arthrit Care Res, 63(8), 1115-1125. https://doi.org/10.1002/acr.20492
  • Chevalier, X. (2010). Intraarticular treatments for osteoarthritis: newperspectives. Curr Drug Targets, 11(5), 546-60. https://doi.org/10.2174/138945010791011866
  • Chimal-Monroy, J., Bravo-Ruíz, T., Furuzawa-Carballeda, G. J., Lira, J. M., de la Cruz, J. C., Almazán, A., Krötzsch-Gómez, F. E., Arrellín, G., & Díaz de León, L. (1998). Collagen-PVP accelerates new bone formation of experimentally induced bone defects in rat skull and promotes the expression of osteopontin and SPARC during bone repair of rat femora fractures. Annals of the New York Academy of Sciences, 857, 232–236. https://doi.org/10.1111/j.1749-6632.1998.tb10120.x
  • Citaker, S., Gündüz, A.G., Güçlü, M.B, Nazliel, B., Irkeç, C. (2011). Relationship between foot sensation and standing balance in patients with multiple sclerosis. Gait & Posture, 34(2), 275-278. https://doi.org/10.1002/acr.20492
  • Crowley, D. C., Lau, F. C., Sharma, P., Evans, M., Guthrie, N., Bagchi, M., Bagchi, D., Dey, D. K., & Raychaudhuri, S. P. (2009). Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. International Journal of Medical Sciences, 6(6), 312–321. https://doi.org/10.7150/ijms.6.312
  • Cucchiarini, M., Henrionnet, C., Mainard, D., Pinzano, A., & Madry, H. (2015). New trends in articular cartilage repair. Journal of Experimental Orthopaedics, 2(1), 8. https://doi.org/10.1186/s40634-015-0026-0
  • Cushman, D.M., Ofek, E., Syed, R.H., Clements, N., Gardner, J.E., Sams, J.M., Mulvey, J. L., & McCormick, Z. L. (2019). Comparison of Varying Corticosteroid Type, Dose, and Volume for the Treatment of Pain in Small- and Intermediate-Size Joint Injections: A Narrative Review. PM R, 11(7), 758-770. https://doi.org/10.1016/j.pmrj.2018.09.040
  • Dennison, E., Cooper, C. (2003). Osteoarthritis: epidemiology and classification. Hochberg MC., Silman AJ., Smolen JS., Weinblatt ME, Weisman MH (Eds), Rheumatol (1781-1791). 3rd ed. Edinburgh: Mosby.
  • Deshpande, BR., Katz, JN., Solomon, DH., Yelin EH., Hunter DJ., Messier SP., Suter L., Losina E. (2016). Number of persons with symptomatic knee osteoarthritis in the US: impact of race and ethnicity, age, sex, and obesity. Arthritis Care & Research, 68(12), 1743-1750. https://doi.org/10.1002/acr.22897
  • Ertürk, C., Altay, M.A., Altay, N., Kalender, A.M., Öztürk, İ.A. (2016). Will a single periarticular lidocaine-corticosteroid injection improve the clinical efficacy of intraarticular hyaluronic acid treatment of symptomatic knee osteoarthritis? Knee Surg Sports Traumatol Arthrosc, 24(11), 3653-3660. https://doi.org/10.1007/s00167-014-3398-2
  • Fisher, N.M., Gresham, G.E., Abrams, M., Hicks J., Horrigan, D., Pendergast DR. (1993). Quantitative Effects Of Physical Therapy On Muscular And Functional Performance İn Subjects With Osteoarthritis Of The Knees. Arch Phys Med Rehabil, 74, 840-847. https://doi.org/10.1016/0003-9993(93)90011-x
  • Fitzgerald, G.K., Piva, S.R., Irrgang, J.J. (2004). Reports of joint instability in knee osteoarthritis: its prevalence and relationship to physical function. Arthritis Care & Research, 51(6), 941-946. https://doi.org/10.1002/art.20825
  • Fransen, M, McConnell, S, Harmer, A.R, Van der Esch, M, Simic, M., Bennell KL. (2015). Exercise for osteoarthritis of the knee: a Cochrane systematic review. British Journal of Sports Medicine, 49(24), 1554-1557. https://doi.org/10.1136/bjsports-2015-095424
  • Furuzawa-Carballeda, J., Alcocer-Varela, J., & Diaz de León, L. (1999). Collagen-PVP decreases collagen turnover in synovial tissue cultures from rheumatoid arthritis patients. Annals of the New York Academy of Sciences, 878, 598–602. https://doi.org/10.1111/j.1749-6632.1999.tb07738.x
  • Furuzawa-Carballeda, J., Muñoz-Chablé, O. A., Macías-Hernández, S. I., & Agualimpia-Janning, A. (2009). Effect of polymerized-type I collagen in knee osteoarthritis. II. In vivo study. European Journal of Clinical Investigation, 39(7), 598–606. https://doi.org/10.1111/j.1365-2362.2009.02144.x
  • Goldring, M.B., Otero, M. (2011). Inflammation in osteoarthritis. Current Opinion in Rheumatology, 23(5), 471-478. https://doi.org/10.1097/BOR.0b013e328349c2b1
  • Hackett, G.S. , Hemwall, G.A. , Montgomery, G.A. (1993). Ligament and Tendon Relaxation Treated by Prolotherapy. 5th edition. Oak Park (IL): Gustav A. Hemwall. Erişim: https://www.scirp.org/(S(351jmbntvnsjt1aadkposzje))/reference/ReferencesPapers.aspx?ReferenceID=1881092
  • Hassan, F., Trebinjac, S., Murrell, W. D., & Maffulli, N. (2017). The effectiveness of prolotherapy in treating knee osteoarthritis in adults: a systematic review. British Medical Bulletin, 122(1), 91–108. https://doi.org/10.1093/bmb/ldx006
  • Heidari, B. (2011). Knee osteoarthritis prevalence, risk factors, pathogenesis and features: Part I. Caspian J Intern Med, 2(2), 205-212. Erişim: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766936/
  • Hinton, R., Moody, R.L., Davis, A.W., Thomas, S.F. (2002). Osteoarthritis: diagnosis and therapeutic considerations. Am Fam Physician, 65(5), 841-849. Erişim: https://www.aafp.org/pubs/afp/issues/2002/0301/p841.html
  • Hurley, M.V., Scott, D.L., Rees, J., Nweham, DJ. (1997). Sensorimotor changes and functional performance in patients with knee osteoarthritis. Ann Rheum Dis, 56, 641-648. https://doi.org/10.1136/ard.56.11.641
  • Iannitti, T., Lodi, D. & Palmieri, B. (2011). Intra-Articular Injections for the Treatment of Osteoarthritis. Drugs R.D., 11, 13-27. https://doi.org/10.2165/11539760-000000000-00000 Jüni, P., Hari, R., Rutjes, AW., Fischer, R., Silletta, MG., Reichenbach, S., Bruno, C. (2015). Intra-articular corticosteroid for knee osteoarthritis. Cochrane Database Syst Rev, (10). https://doi.org/10.1002/14651858.CD005328.pub3
  • Kruse, D.W. (2008). Intraarticular injection for osteoarthritis of the hip. Is it effective? Is it safe? Curr Rev. Musculoskelet Med , 1(3- 4), 227-233. https://doi.org/10.1007/s12178-008-9029-0 Laver, L., Marom, N., Dnyanesh, L., Mei-Dan, O., Espregueira-Mendes, J., & Gobbi, A. (2017). PRP for Degenerative Cartilage Disease: A Systematic Review of Clinical Studies. Cartilage, 8(4), 341–364. https://doi.org/10.1177/1947603516670709
  • Linetsky, F., Saberski, L., Dubin, J. A., Miguel, R., & Wilkinson, H. (2004). Re: Yelland MJ, Glasziou PP, Bogduk N, et al. Prolotherapy injections, saline injections, and exercises for chronic low-back pain: a randomized study. Spine, 29(16), 1840–1843. https://doi.org/10.1097/00007632-200408150-00033
  • Manlapaz, D.G., Sole G., Jayakaran, P., Chapple, C.M. (2019). Risk factors for falls in adults with knee osteoarthritis: a systematic review. PMR, 11(7), 745-757. https://doi.org/10.1002/pmrj.12066 McCrum, C. (2016). Therapeutic Review of Methylprednisolone Acetate Intra-Articular Injection in the Management of Osteoarthritis of the Knee-Part 2: Clinical and Procedural Considerations. Musculoskeletal Care, 14(4), 252-266. https://doi.org/10.1002/msc.1145
  • Migliore, A., Giovannangeli, F., Granata, M., Laganà B. (2010). Hylan g-f 20: review of its safety and efficacy in the management of joint pain in osteoarthritis. Clin Med Insights Arthritis Musculoskelet Disord, 3, 55-68. Erişim: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998981/pdf/cmamd-2010-055.pdf
  • Milants, C., Bruyère, O., & Kaux, J. F. (2017). Responders to Platelet-Rich Plasma in Osteoarthritis: A Technical Analysis. BioMed Research International. https://doi.org/10.1155/2017/7538604
  • Morehead, K., & Sack, K. E. (2003). Osteoarthritis. What therapies for this disease of many causes?. Postgraduate Medicine, 114(5), 11–17. https://doi.org/10.3810/pgm.2003.11.1521
  • Ondrésik, M., Azevedo Maia, F. R., da Silva Morais, A., Gertrudes, A. C., Dias Bacelar, A. H., Correia, C., Gonçalves, C., Radhouani, H., Amandi Sousa, R., Oliveira, J. M., & Reis, R. L. (2017). Management of knee osteoarthritis. Current status and future trends. Biotechnology and Bioengineering, 114(4), 717–739. https://doi.org/10.1002/bit.26182
  • Pak, J., Lee, J. H., Park, K. S., Park, M., Kang, L. W., & Lee, S. H. (2017). Current use of autologous adipose tissue-derived stromal vascular fraction cells for orthopedic applications. Journal of Biomedical Science, 24(1), 9. https://doi.org/10.1186/s12929-017-0318-z
  • Pavone, V., Vescio, A., Turchetta, M., Giardina, S.M.C., Culmone, A., Testa, G. (2021). Injection-Based Management of Osteoarthritis of the Knee: A Systematic Review of Guidelines. Front Pharmacol, 12, 661-805. https://doi.org/10.3389/fphar.2021.661805
  • Peat, G., McCarney R., Croft, P. (2001). Knee Pain And Osteoarthritis İn Older Adults: A Review Of Community Burden And Current Use Of Primary Health Care. Ann Rheum Dis, 60, 91-97. https://doi.org/10.1136/ard.60.2.91
  • Rabago, D., Patterson, J. J., Mundt, M., Kijowski, R., Grettie, J., Segal, N. A., & Zgierska, A. (2013). Dextrose prolotherapy for knee osteoarthritis: a randomized controlled trial. Annals of Family Medicine, 11(3), 229–237. https://doi.org/10.1370/afm.1504
  • Rabago, D., Zgierska, A., Fortney, L., Kijowski, R., Mundt, M., Ryan, M., Grettie, J., & Patterson, J. J. (2012). Hypertonic dextrose injections (prolotherapy) for knee osteoarthritis: results of a single-arm uncontrolled study with 1-year follow-up. Journal of Alternative and Complementary Medicine (New York, N.Y.), 18(4), 408–414. https://doi.org/10.1089/acm.2011.0030
  • Raeissadat, S. A., Rayegani, S. M., Hassanabadi, H., Fathi, M., Ghorbani, E., Babaee, M., & Azma, K. (2015). Knee Osteoarthritis Injection Choices: Platelet- Rich Plasma (PRP) Versus Hyaluronic Acid (A one-year randomized clinical trial). Clinical medicine insights. Arthritis and Musculoskeletal Disorders, 8, 1–8. https://doi.org/10.4137/CMAMD.S17894
  • Raynauld, J.P., Buckland-Wright, C., Ward, R., Choquette, D., Haraoui, B., Martel-Pelletier, J., Uthman, I., Khy, V., Tremblay, J.L., Bertrand, C., Pelletier, J.P. (2003). Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum, 48(2), 370-7. https://doi.org/10.1002/art.10777
  • Richardson, S. S., Schairer, W. W., Sculco, T. P., & Sculco, P. K. (2019). Comparison of Infection Risk with Corticosteroid or Hyaluronic Acid Injection Prior to Total Knee Arthroplasty. The Journal of Bone and Joint Surgery. 101(2), 112–118. https://doi.org/10.2106/JBJS.18.00454
  • Sampson, S., Botto-van Bemden, A., & Aufiero, D. (2015). Stem cell therapies for treatment of cartilage and bone disorders: osteoarthritis, avascular necrosis, and non-union fractures. PM & R : The Journal of Injury, Function, and Rehabilitation, 7(4 Suppl), S26–S32. https://doi.org/10.1016/j.pmrj.2015.01.023
  • Schumacher, H.R, Chen, L. X. (2005). Injectable corticosteroids in treatment of arthritis of the knee. Am J Med, 118(11), 1208-1214. https://doi.org/10.1016/j.amjmed.2005.05.003
  • Sconza, C, Di Matteo, B., Queirazza, P., Dina, A., Amenta, R., Respizzi, S., Massazza, G., Ammendolia, A., Kon E., de Sire A. (2023). Diz Osteoartriti Olan Hastalarda Ağrı Giderme için Ozon Tedavisine Karşı Hyaluronik Asit Enjeksiyonları: Ön Bulgular Randomize Kontrollü Bir Çalışmadan Moleküler ve Klinik Sonuçlar. Uluslararası Moleküler Bilimler Dergisi , 24(10), 8788. https://doi.org/10.3390/ijms24108788
  • Shen, L., Yuan, T., Chen, S., Xie, X., & Zhang, C. (2017). The temporal effect of platelet-rich plasma on pain and physical function in the treatment of knee osteoarthritis: systematic review and meta-analysis of randomized controlled trials. Journal of Orthopaedic Surgery and Research, 12(1), 16. https://doi.org/10.1186/s13018-017-0521-3
  • Sinusas, K. (2012). Osteoarthritis: diagnosis and treatment. American Family Physician, 85(1), 49-56. Erişim: https://www.aafp.org/pubs/afp/issues/2012/0101/p49.html Stone, S., Malanga, G.A., Capella, T. (2021). Corticosteroids: Review of the History, the Effectiveness, and Adverse Effects in the Treatment of Joint Pain. Pain Physician, 24, 233-46. Erişim: https://www.painphysicianjournal.com/linkout?issn=&vol=24&page=S233
  • Sucuoğlu, H., & Üstünsoy, S. (2019). The short-term effect of PRP on chronic pain in knee osteoarthritis. Diz osteoartritinde PRP'nin kronik ağrı üzerine kısa dönem etkinliği. The Journal of the Turkish Society of Algology, 31(2), 63–69. https://doi.org/10.14744/agri.2019.81489
  • Uson, J., Rodriguez-García, S.C., Castellanos-Moreira, R., O'Neill, T. W., Doherty, M., Boesen, M., Pandit, H., Möller Parera, I., Vardanyan, V., Terslev, L., Kampen, W. U., D'Agostino, M. A., Berenbaum, F., Nikiphorou, E., Pitsillidou, I. A., de la Torre-Aboki, J., Carmona, L., & Naredo, E. (2021). EULAR recommendations for intra-articular therapies. Annals of the Rheumatic Diseases, 80 (10), 1299-1305. https://doi.org/10.1136/annrheumdis-2021-220266
  • Watt F. E., Gulati M. (2017). New Drug Treatments for Osteoarthritis: What is on the horizon? EMJ, 2, 50-8. Erişim : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198938/
  • Yokota, N., Yamakawa, M., Shirata, T., Kimura, T., & Kaneshima, H. (2017). Clinical results following intra-articular injection of adipose-derived stromal vascular fraction cells in patients with osteoarthritis of the knee. Regenerative Therapy, 6, 108–112. https://doi.org/10.1016/j.reth.2017.04.002
  • Zhang, Y., Jordan, JM. (2010). Epidemiology of osteoarthritis. Clin Geriatr Med, 26, 355-369. https://doi.org/10.1016/j.cger.2010.03.001
Toplam 57 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Fizyoterapi
Bölüm Derlemeler
Yazarlar

Sevde Nur Aktaş Bu kişi benim 0000-0002-2590-9160

Metehan Yana 0000-0002-9290-1716

Yayımlanma Tarihi 21 Aralık 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 3 Sayı: 3

Kaynak Göster

APA Aktaş, S. N., & Yana, M. (2023). Diz Osteoartritte Enjeksiyon Yöntemleri. Unika Sağlık Bilimleri Dergisi, 3(3), 608-622.
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