Araştırma Makalesi
BibTex RIS Kaynak Göster

Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram

Yıl 2017, Cilt: 28 Sayı: 1, 37 - 40, 20.04.2017

Öz

In this study, the effects of total aflatoxin (AF) given orally on
kidney in Merino rams were studied. In addition, this study was conducted in
order to evaluate the efficacy of an esterified glucomannan (EG) for protection
against to aflatoxicosis. One year-old 32 Merino rams were divided into four
equal groups. Rams were fed through the 92 days. Control group (C) fed with the
commercial feed. AF group fed with commercial feed added 250 µg/day of total AF. EG group fed with commercial feed added 2
g/day of EG. AF+EG group fed with commercial feed added 250 µg/day of total AF
and 2 g/day of EG. At the end of the 92 day after cessation of the
animals, tissue samples were taken from the kidney in order to perform
histological structure. Degeneration and spills in the tubular epithelial cells
of kidney were observed in the AF group. Massive hyperemia was observed in the
renal vessels. In conclusion, the adverse effects causing by aflatoxicosis on
the kidney could be ameliorated by adding EG to the ration.

Kaynakça

  • Agag BI (2004). Mycotoxins in food and feeds 1-aflatoxins. Ass Univ Bul Environ. Res, 7(1), 173-205. Appelgren LE, Arora RG (1983). Distribution of 14C-labelled ochratoxin A in pregnant mice. Food Chem Toxicol, 21, 563-568. Arora RG, Appelgren LE, Bergman A (1978). Distribution of [14C]-labeled aflatoxin B1 in mice. Acta Pharmacol Toxicol, 43, 273-279. Asplin FD, Carnaghan RB (1961). The toxicity of certain groundnut meals for poultry with special reference to their effect on ducklings and chickens. Vet Res, 73, 1215-1219. Basmacıoglu H, Oguz H, Ergul M, Col R, Birdane YO (2005). Effect of dietary esterified glucomannan on performance, serum biochemistry and haematology in broilers exposed to aflatoxin. Czech J Anim Sci, 50(1), 31-39. Boonyaratpalin M, Supamattaya K, Verakunpiriya V, Suprasert D (2001). Effects of aflatoxin B1 on growth performance, blood components, immune function and histopathological changes in black tiger shrimp (Penaeus monodon fabricius). Aquacult Res, 32, 388-398. Calnek BW, Barnes HJ, Beard W, Mcdougald LR, Saif YM (1997). Diseases of poultry, 10th edition, Iowa State Univ Press, Ames, IA, 1080 pp. Colakoglu F, Donmez HH (2013). Effects of aflatoxin on AgNOR activity of cells in different regions of kidney, and protective effectiveness of esterified glucomannan in ram. Kafkas Vet Derg, 19(3), 505-509. Dafalla R, Yagi AI, Adam SEI (1987). Experimental aflatoxicosis in Hybro-type chicks: Sequential changes in growth and serum constituents and histopathological changes. Vet Human Toxicol, 29, 222-225. Demet O, Oguz H, Celik I, Nizamlıoglu F (1995). Pirinçte aflatoksin üretilmesi. Vet Bil Derg, 11(1), 19-23. Denning DW (1987). Aflatoxin and human disease. Adverse Drug React Acute Pois Rev, 4, 175. Eraslan G, Karaoz E, Bilgili A, Akdogan M, Oncu M, Essiz D (2003). The effects of aflatoxin on kidney function in broiler chicks. Turk J Vet Anim Sci, 27, 741-749. Fink GJ (1999). Mycotoxins: Their implications for human and animal health. Vet Quart, 21, 115-120. Glahn RP, Beers KW, Bottje WG, Wideman RF JR, Huff WE, Thomas W (1991). Aflatoxicosis alters avian renal function, calcium and vitamin D metabolism. J Toxicol Environ Health, 34(3), 309-321. Grosman ME, Elias MM, Comin EJ, Rodriguez Garay EA (1984). Distal nephron function of the rat during acute aflatoxicosis. Toxicol Lett, 21(3), 263-270. Ikegwuonu FI, Egbunike GN, Emerole GO, Aire TA (1980). The effects of aflatoxin B1 on some testicular and kidney enzyme activity in rat. Toxicology, 17(1), 9-16. Kececi T, Oguz H, Kurtoglu V, Demet O (1998). Effects of polyvinylpolypyrrolidone, synthetic zeolite and bentonite on serum biochemical and haemetological characters of broiler chickens during aflatoxicosis. Br Poult Sci, 39(3), 452-458. Lakkawar AW, Chattopadhyay SK, Johri TS (2004). Experimental aflatoxin B1 toxicosis in young rabbits-a clinical and patho-anatomical study. Slov Vet Res, 41(2), 73-81. Maull EA (1988). Developmental toxicities of aflatoxins B1 and G1: In vivo and in vitro Assessments. Texas A&M University, College Station, TX. (Ph. D. Dissertation). Morrissey RE, Norred WP, Hinton DM (1987). Combined effects of the mycotoxins aflatoxin B1 and Cyclopiazonic acid on Sprague-Dawley rats. Food Chem Toxicol, 25, 837–842. Newberne PM, Rogers AE (1981). Animal toxicity of major enviromental mycotoxins. In: Enviromental Risks, Shanks RC (Ed), pp. 51-106, CRC Press, Boca Ralton, Florida. Oguz H, Hadimli HH, Kurtoglu V, Erganis O (2003). Evaluation of humoral immunity of broilers during chronic aflatoxin (50 and 100 ppb) and clinoptilolite exposure. Revue Med Vet, 154(7), 483-486. Oguz H (2011). A review from experimental trials on detoxification of aflatoxin in poultry feed. Eurasion J Vet Sci, 27(1), 1-12. Ortatatlı M, Oguz H, Hatipoglu F, Karaman M ( 2005). Evaluation of of pathological changes in broilers during chronic aflatoxin (50 and 100 ppb) and clinoptilolite exposure. Research in Veterinary Science, 78, 61-68. Ozen H, Karaman M, Cigremis Y, Tuzcu M, Ozcan K, Erdag D (2009). Effectiveness of melatonin on aflatoxicosis in chicks. Res Vet Sci, 86, 485-489. Pohland AE (1993). Mycotoxin in review. Food Add Contam, 10, 17-28. Shen HM, Ong CN, Shi CY (2005). Involvement of reactive oxygen species in aflatoxin B1 induced cell injury in cultured rat hepatocytes. Toxicol, 99(1-2): 115-123. Shotwell OL, Hasseltine CW, Stubblefield RD, Sorenson WG (1966). Production of aflatoxin on rice. Appl Microbiol, 5, 425-429. Stanley VG, Ojo R, Woldensenbet S, Hutchinson DH (1993). The use of Saccharomyces cerevisiae, to suppres the effect of aflatoxicosis in broiler chicks. Poult Sci, 72, 1867–1872. Stroka J, Anklam E, Otterdijk R (2000). Immunoaffinity columnclean-up prior to thin layer chromatography for determination of aflatoxins in various food matrices. J Chromat A, 904, 251-256. Unal T (2012). Hemodinamik bozukluklar, Ege Unv Dis Hekimligi Fak, 1-11. Ustunel I, Demir R (2001). Histolojik boyama teknikleri. Palme Yayıncılık, Ankara. Vicam LP (1999). Fluorometer USDA-FGIS procedure for corn, corn meal, corn/soy blend, milled rice, popcorn, sorghum and soybeans. Afla Test Instruction Manuel, USA. Wilson DM, Payne GA (1994). The toxicology of aflatoxins: human health, veterinary and agricultural significance. Academic Press, London. Yiannikouris A, Poughon L, Cameleyre X (2003). A novel technique to evaluate interactions between Saccharomyces cerevisiae cell wall and mycotoxins: application to zearalenone. Biotechnol Lett,25(10): 783-789. Yiannikouris A, Bertin G, Jouany JP (2005). Reducing mycotoxin impact: the science behind Mycosorb. In: Lyons TP, Jacques KA (Eds), Nutritional Biotechnology in the Feed and Food Industries, Proceedings of Alltech’s 21st Annual Symposium, 22-25 May 2005, Lexington, Kentucky, USA, Alltech UK, Stamford, UK, pp.265-276. Yıldırım E, Yalcinkaya I, Kanbur M, Cinar M, Oruc E (2011). Effects of yeast glucomannan on performance, some biochemical parameters anf pathological changes in experimental aflatoxicosis in broilers chickens. Revue Med Vet, 162(8-9), 413-420.

Koçlarda Aflatoksinin Böbrek Üzerine Etkileri ve Esterifiye Glukomannanın Koruyucu Etkinliği

Yıl 2017, Cilt: 28 Sayı: 1, 37 - 40, 20.04.2017

Öz

Bu
çalışmada Merinos ırkı koçlara ağızdan verilen total aflatoksinin (AF) böbrek
üzerine etkileri ile glukomannanın (EG) koruyucu etkinliği değerlendirildi.
Çalışmada 1 yaşında 32 adet koç 4 eşit gruba ayrıldı. Beslemeye 92 gün devam
edildi. Kontrol (K) grubuna ticari yem; AF grubuna ticari yem ile günlük 250 µg
AF; EG grubuna ticari yem ile günlük 2 gr EG; AF+EG grubuna ise ticari yemle
birlikte günlük 250 µg AF ve 2 gr EG verildi. 92. günün sonunda hayvanlar kesildikten sonra böbrekteki histolojik
yapıyı göstermek için örnekler alındı. AF grubunun böbrek tübüllerinde
dejenerasyon ve dökülmeler, böbrek damarlarında ise yoğun hiperemi gözlendi. Sonuç olarak; aflatoksikozun böbrek üzerindeki olumsuz
etkilerinin yeme EG ilave edilerek iyileştirilebildiği ortaya konmuştur.

Kaynakça

  • Agag BI (2004). Mycotoxins in food and feeds 1-aflatoxins. Ass Univ Bul Environ. Res, 7(1), 173-205. Appelgren LE, Arora RG (1983). Distribution of 14C-labelled ochratoxin A in pregnant mice. Food Chem Toxicol, 21, 563-568. Arora RG, Appelgren LE, Bergman A (1978). Distribution of [14C]-labeled aflatoxin B1 in mice. Acta Pharmacol Toxicol, 43, 273-279. Asplin FD, Carnaghan RB (1961). The toxicity of certain groundnut meals for poultry with special reference to their effect on ducklings and chickens. Vet Res, 73, 1215-1219. Basmacıoglu H, Oguz H, Ergul M, Col R, Birdane YO (2005). Effect of dietary esterified glucomannan on performance, serum biochemistry and haematology in broilers exposed to aflatoxin. Czech J Anim Sci, 50(1), 31-39. Boonyaratpalin M, Supamattaya K, Verakunpiriya V, Suprasert D (2001). Effects of aflatoxin B1 on growth performance, blood components, immune function and histopathological changes in black tiger shrimp (Penaeus monodon fabricius). Aquacult Res, 32, 388-398. Calnek BW, Barnes HJ, Beard W, Mcdougald LR, Saif YM (1997). Diseases of poultry, 10th edition, Iowa State Univ Press, Ames, IA, 1080 pp. Colakoglu F, Donmez HH (2013). Effects of aflatoxin on AgNOR activity of cells in different regions of kidney, and protective effectiveness of esterified glucomannan in ram. Kafkas Vet Derg, 19(3), 505-509. Dafalla R, Yagi AI, Adam SEI (1987). Experimental aflatoxicosis in Hybro-type chicks: Sequential changes in growth and serum constituents and histopathological changes. Vet Human Toxicol, 29, 222-225. Demet O, Oguz H, Celik I, Nizamlıoglu F (1995). Pirinçte aflatoksin üretilmesi. Vet Bil Derg, 11(1), 19-23. Denning DW (1987). Aflatoxin and human disease. Adverse Drug React Acute Pois Rev, 4, 175. Eraslan G, Karaoz E, Bilgili A, Akdogan M, Oncu M, Essiz D (2003). The effects of aflatoxin on kidney function in broiler chicks. Turk J Vet Anim Sci, 27, 741-749. Fink GJ (1999). Mycotoxins: Their implications for human and animal health. Vet Quart, 21, 115-120. Glahn RP, Beers KW, Bottje WG, Wideman RF JR, Huff WE, Thomas W (1991). Aflatoxicosis alters avian renal function, calcium and vitamin D metabolism. J Toxicol Environ Health, 34(3), 309-321. Grosman ME, Elias MM, Comin EJ, Rodriguez Garay EA (1984). Distal nephron function of the rat during acute aflatoxicosis. Toxicol Lett, 21(3), 263-270. Ikegwuonu FI, Egbunike GN, Emerole GO, Aire TA (1980). The effects of aflatoxin B1 on some testicular and kidney enzyme activity in rat. Toxicology, 17(1), 9-16. Kececi T, Oguz H, Kurtoglu V, Demet O (1998). Effects of polyvinylpolypyrrolidone, synthetic zeolite and bentonite on serum biochemical and haemetological characters of broiler chickens during aflatoxicosis. Br Poult Sci, 39(3), 452-458. Lakkawar AW, Chattopadhyay SK, Johri TS (2004). Experimental aflatoxin B1 toxicosis in young rabbits-a clinical and patho-anatomical study. Slov Vet Res, 41(2), 73-81. Maull EA (1988). Developmental toxicities of aflatoxins B1 and G1: In vivo and in vitro Assessments. Texas A&M University, College Station, TX. (Ph. D. Dissertation). Morrissey RE, Norred WP, Hinton DM (1987). Combined effects of the mycotoxins aflatoxin B1 and Cyclopiazonic acid on Sprague-Dawley rats. Food Chem Toxicol, 25, 837–842. Newberne PM, Rogers AE (1981). Animal toxicity of major enviromental mycotoxins. In: Enviromental Risks, Shanks RC (Ed), pp. 51-106, CRC Press, Boca Ralton, Florida. Oguz H, Hadimli HH, Kurtoglu V, Erganis O (2003). Evaluation of humoral immunity of broilers during chronic aflatoxin (50 and 100 ppb) and clinoptilolite exposure. Revue Med Vet, 154(7), 483-486. Oguz H (2011). A review from experimental trials on detoxification of aflatoxin in poultry feed. Eurasion J Vet Sci, 27(1), 1-12. Ortatatlı M, Oguz H, Hatipoglu F, Karaman M ( 2005). Evaluation of of pathological changes in broilers during chronic aflatoxin (50 and 100 ppb) and clinoptilolite exposure. Research in Veterinary Science, 78, 61-68. Ozen H, Karaman M, Cigremis Y, Tuzcu M, Ozcan K, Erdag D (2009). Effectiveness of melatonin on aflatoxicosis in chicks. Res Vet Sci, 86, 485-489. Pohland AE (1993). Mycotoxin in review. Food Add Contam, 10, 17-28. Shen HM, Ong CN, Shi CY (2005). Involvement of reactive oxygen species in aflatoxin B1 induced cell injury in cultured rat hepatocytes. Toxicol, 99(1-2): 115-123. Shotwell OL, Hasseltine CW, Stubblefield RD, Sorenson WG (1966). Production of aflatoxin on rice. Appl Microbiol, 5, 425-429. Stanley VG, Ojo R, Woldensenbet S, Hutchinson DH (1993). The use of Saccharomyces cerevisiae, to suppres the effect of aflatoxicosis in broiler chicks. Poult Sci, 72, 1867–1872. Stroka J, Anklam E, Otterdijk R (2000). Immunoaffinity columnclean-up prior to thin layer chromatography for determination of aflatoxins in various food matrices. J Chromat A, 904, 251-256. Unal T (2012). Hemodinamik bozukluklar, Ege Unv Dis Hekimligi Fak, 1-11. Ustunel I, Demir R (2001). Histolojik boyama teknikleri. Palme Yayıncılık, Ankara. Vicam LP (1999). Fluorometer USDA-FGIS procedure for corn, corn meal, corn/soy blend, milled rice, popcorn, sorghum and soybeans. Afla Test Instruction Manuel, USA. Wilson DM, Payne GA (1994). The toxicology of aflatoxins: human health, veterinary and agricultural significance. Academic Press, London. Yiannikouris A, Poughon L, Cameleyre X (2003). A novel technique to evaluate interactions between Saccharomyces cerevisiae cell wall and mycotoxins: application to zearalenone. Biotechnol Lett,25(10): 783-789. Yiannikouris A, Bertin G, Jouany JP (2005). Reducing mycotoxin impact: the science behind Mycosorb. In: Lyons TP, Jacques KA (Eds), Nutritional Biotechnology in the Feed and Food Industries, Proceedings of Alltech’s 21st Annual Symposium, 22-25 May 2005, Lexington, Kentucky, USA, Alltech UK, Stamford, UK, pp.265-276. Yıldırım E, Yalcinkaya I, Kanbur M, Cinar M, Oruc E (2011). Effects of yeast glucomannan on performance, some biochemical parameters anf pathological changes in experimental aflatoxicosis in broilers chickens. Revue Med Vet, 162(8-9), 413-420.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Makaleler
Yazarlar

Fatma Çolakoğlu

Hasan Hüseyin Dönmez

Yayımlanma Tarihi 20 Nisan 2017
Gönderilme Tarihi 6 Ekim 2016
Kabul Tarihi 21 Kasım 2016
Yayımlandığı Sayı Yıl 2017 Cilt: 28 Sayı: 1

Kaynak Göster

APA Çolakoğlu, F., & Dönmez, H. H. (2017). Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram. Van Veterinary Journal, 28(1), 37-40.
AMA Çolakoğlu F, Dönmez HH. Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram. Van Vet J. Nisan 2017;28(1):37-40.
Chicago Çolakoğlu, Fatma, ve Hasan Hüseyin Dönmez. “Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram”. Van Veterinary Journal 28, sy. 1 (Nisan 2017): 37-40.
EndNote Çolakoğlu F, Dönmez HH (01 Nisan 2017) Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram. Van Veterinary Journal 28 1 37–40.
IEEE F. Çolakoğlu ve H. H. Dönmez, “Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram”, Van Vet J, c. 28, sy. 1, ss. 37–40, 2017.
ISNAD Çolakoğlu, Fatma - Dönmez, Hasan Hüseyin. “Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram”. Van Veterinary Journal 28/1 (Nisan 2017), 37-40.
JAMA Çolakoğlu F, Dönmez HH. Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram. Van Vet J. 2017;28:37–40.
MLA Çolakoğlu, Fatma ve Hasan Hüseyin Dönmez. “Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram”. Van Veterinary Journal, c. 28, sy. 1, 2017, ss. 37-40.
Vancouver Çolakoğlu F, Dönmez HH. Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram. Van Vet J. 2017;28(1):37-40.

88x31.png

Kabul edilen makaleler Creative Commons Atıf-Ticari Olmayan Lisansla Paylaş 4.0 uluslararası lisansı ile lisanslanmıştır.