Derleme
BibTex RIS Kaynak Göster

ARI ÜRÜNLERİ ve APİTERAPİ

Yıl 2019, Cilt: 10 Sayı: 1, 1 - 15, 20.05.2019

Ali Sorucu

Öz

Doğal ürünler binlerce yıldır sağlığın korunması ve hastalıkların tedavisi için kullanılmıştır. Çin, Hint,
Kuzey Amerika yerlileri, Mısır ve Sümerliler gibi antik uygarlıklar hastalıklara karşı doğal ürünleri
kullanmışlardır. Son yıllarda kimyasal ilaçların usulü dışında kullanımına bağlı gelişen ilaç direnci ve yan etkileri
ve kanser vakalarının artışı modern tıbbı alternatif çözümler aramaya yönlendirmiştir. Arı ürünleri de alternatif
tedavi seçeneklerinin en önemlileri arasındadır. Çin, Rusya, Romanya ve bazı doğu Avrupa ülkelerinde
hastalıkların arı ürünleriyle tedavi edildiği köklü apiterapi merkezleri bulunmaktadır. Ülkemizde de son yıllarda
bu alanda çalışmalar başlatılarak, 2014 yılında yayınlanan geleneksel ve tamamlayıcı tıp uygulamaları
yönetmeliğiyle birlikte apiterapi kursları ve merkezleri kurulmaya başlanmıştır.
Arı ürünleri denildiği zaman ilk akla gelen bal, polen ve balmumudur, fakat bu ürünler buz dağının görünen
kısmıdır. Bunların dışında bal arısının propolis, arı sütü, apilarnil, arı zehri, arı ekmeği (perga), apilarnil ve kovan
havası gibi biyolojik öneme sahip önemli ürünleri bulunmaktadır. 

Anahtar Kelimeler

Apiterapi Arı zehiri Bal Polen Propolis

Kaynakça

  • Akhmetova, R., Sibgatullin, J., Garmonov, S., & Akhmetova, L. (2012). Technology for extraction of bee-bread from the honeycomb. Procedia Engineering, 42, 1822-1825.
  • Al-Mamary, M., Al-Meeri, A., & Al-Habori, M. (2002). Antioxidant activities and total phenolics of different types of honey. Nutrition research, 22(9), 1041-1047.
  • Altan, Ö., Yücel, B., Açikgöz, Z., Şeremet, Ç., Kösoğlu, M., Turgan, N., & Özgönül, A. M. (2013). Apilarnil reduces fear and advances sexual development in male broilers but has no effect on growth. British poultry science, 54(3), 355-361.
  • Amoros, M., Sauvager, F., Girre, L., & Cormier, M. (1992). In vitro antiviral activity of propolis. Apidologie, 23(3), 231-240.
  • Annila, I. (2000). Bee venom allergy. Clinical & Experimental Allergy, 30(12), 1682-1687.
  • Aureli, P., Franciosa, G., & Fenicia, L. (2002). Infant botulism and honey in Europe: a commentary. The Pediatric infectious disease journal, 21(9), 866-868.
  • Aydın L, Doğanay A, Oruç HH, Yeşilbağ K, Bakırcı S, Girişkin O, et al. (2017). Bal Arısı Yetiştiriciliği Ürünleri Hastalıkları. Dora Basım Yayım Dağıtım 2017;1. Baskı:155-90.
  • Bankova, V. S., de Castro, S. L., & Marcucci, M. C. (2000). Propolis: recent advances in chemistry and plant origin. Apidologie, 31(1), 3-15.
  • Banskota, A. H., Tezuka, Y., & Kadota, S. (2001). Recent progress in pharmacological research of propolis. Phytotherapy research, 15(7), 561-571.
  • Bărnuţiu, L. I., Mărghitaş, L., Dezmirean, D., Bobiş, O., Mihai, C., & Pavel, C. (2013). Physicochemical composition of Apilarnil (bee drone larvae). Lucrări Ştiinţifice-Seria Zootehnie, 59, 199-202.
  • Basualdo, M., Barragán, S., & Antúnez, K. (2014). Bee bread increases honeybee haemolymph protein and promote better survival despite of causing higher N osema ceranae abundance in honeybees. Environmental microbiology reports, 6(4), 396-400.
  • Benković, V., Knežević, A., Đikić, D., Lisičić, D., Oršolić, N., Bašić, I., & Kopjar, N. (2009). Radioprotective effects of quercetin and ethanolic extract of propolis in gamma-irradiated mice. Archives of Industrial Hygiene and Toxicology, 60(2), 129-138.
  • Bhandari, B., D'Arcy, B., & Kelly, C. (1999). Rheology and crystallization kinetics of honey: present status. International Journal of Food Properties, 2(3), 217-226.
  • Bogdanov, S., Ruoff, K., & Oddo, L. P. (2004). Physico-chemical methods for the characterisation of unifloral honeys: a review. Apidologie, 35(Suppl. 1), S4-S17.
  • Bogdanov, S., Jurendic, T., Sieber, R., & Gallmann, P. (2008). Honey for nutrition and health: a review. Journal of the American College of Nutrition, 27(6), 677-689.
  • Bogdanov, S. (2009). Honey composition. The honey book, 1-9.
  • Bogdanov, S. (2011a). Pollen: nutrition, functional properties, health: a review. Bee Product Science, 1-34.
  • Bogdanov, S. (2011b). Royal jelly, bee brood: composition, health, medicine: a review. Lipids, 3(8), 8-19.
  • Bogdanov, S. (2011c). Bee Venom: Composition, health. Medicine. A review. Bee Prod Sci, 1-20.
  • Bogdanov, S. (2012a). Honey as nutrient and functional food. Proteins, 1100, 1400-2700.
  • Bogdanov, S. (2012b). Pollen: collection, harvest, composition, quality. The bee pollen book.
  • Bogdanov, S. (2012c). Propolis: biological properties and medical applications. The propolis book, 2:1.
  • Buchta, V., Černý, J., & Opletalová, V. (2011). In vitro antifungal activity of propolis samples of Czech and Slovak origin. Open Life Sciences, 6(2), 160-166.
  • Burdock, G. A. (1998). Review of the biological properties and toxicity of bee propolis (propolis). Food and Chemical toxicology, 36(4), 347-363.
  • Campos, M. G., Bogdanov, S., de Almeida-Muradian, L. B., Szczesna, T., Mancebo, Y., Frigerio, C., & Ferreira, F. (2008). Pollen composition and standardisation of analytical methods. Journal of Apicultural Research, 47(2), 154-161.
  • Cirasino, L., Pisati, A., & Fasani, F. (1987). Contact dermatitis from propolis. Contact dermatitis, 16(2), 110-111.
  • Connor, L.J., Muir, R.G. (2013). Pollen and Bee Bread. Am Bee J,153:727-729.
  • Crane, E., Visscher, P.K. (2009). Honey. Encyclopedia of Insects (Second Edition): Elsevier, p. 459-61.
  • De Castro, S. L. (2001). Propolis: biological and pharmacological activities. Therapeutic uses of this bee-product. Annual Review of Biomedical Sciences, 3, 49-83.
  • de Groot, A. C. (2013). Propolis: a review of properties, applications, chemical composition, contact allergy, and other adverse effects. Dermatitis, 24(6), 263-282.
  • Dempsey, C. E. (1990). The actions of melittin on membranes. Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes, 1031(2), 143-161.
  • Duran, N., Muz, M., Culha, G., Duran, G., & Ozer, B. (2011). GC-MS analysis and antileishmanial activities of two Turkish propolis types. Parasitology research, 108(1), 95-105.
  • El-Ghazaly, M. A., Rashed, R. R., & Khayyal, M. T. (2011). Anti-ulcerogenic effect of aqueous propolis extract and the influence of radiation exposure. International journal of radiation biology, 87(10), 1045-1051.
  • Fallico, B., Zappala, M., Arena, E., & Verzera, A. (2004). Effects of conditioning on HMF content in unifloral honeys. Food Chemistry, 85(2), 305-313.
  • Fu, J. Y., Xia, Y., & Zheng, Y. Y. (2004). Antimutagenicity of propolis against some mutagens in vivo and in vitro. Biomed Environ Sci, 17(4), 469-75.
  • Gauldie, J., HANSON, J. M., RUMJANEK, F. D., SHIPOLINI, R. A., & VERNON, C. A. (1976). The peptide components of bee venom. European journal of biochemistry, 61(2), 369-376.
  • Ghisalberti, E. L. (1979). Propolis: a review. Bee world, 60(2), 59-84.
  • Ginsberg, N. J., Dauer, M., & SLOTTA, K. H. (1968). Melittin used as a protective agent against X-irradiation. Nature, 220(5174), 1334.
  • Giusti, F., Miglietta, R., Pepe, P., & Seidenari, S. (2004). Sensitization to propolis in 1255 children undergoing patch testing. Contact dermatitis, 51(5‐6), 255-258.
  • Gleiter, R. A., Horn, H., & Isengard, H. D. (2006). Influence of type and state of crystallisation on the water activity of honey. Food chemistry, 96(3), 441-445.
  • Gunduz, A., Turedi, S., Uzun, H., & Topbas, M. (2006). Mad honey poisoning. The American journal of emergency medicine, 24(5), 595-598.
  • Hepburn, H. R., Radloff, S. E., Duangphakdee, O., & Phaincharoen, M. (2009). Interspecific utilisation of wax in comb building by honeybees. Naturwissenschaften, 96(6), 719-723.
  • Hepburn, H.R., Pirk, C.W.W., Duangphakdee, O. (2016). Honeybee nests. Springer-Verlag Berlin An.
  • Huang, S., Zhang, C. P., Wang, K., Li, G., & Hu, F. L. (2014). Recent advances in the chemical composition of propolis. Molecules, 19(12), 19610-19632.
  • János, K.R. (2015). Bee Hive Air therapies in Central-Europe. No Bees No Life Apitherapy Symposium 2015;Lukovica and Maribor, Slovenia, 23rd-24th October.
  • Jeng, S. N., Shih, M. K., Kao, C. M., Liu, T. Z., & Chen, S. C. (2000). Antimutagenicity of ethanol extracts of bee glue against environmental mutagens. Food and chemical toxicology, 38(10), 893-897.
  • Khalil, M. I., Sulaiman, S. A., & Boukraa, L. (2010). Antioxidant properties of honey and its role in preventing health disorder. The Open Nutraceuticals Journal, 3(1).
  • Koca, I., & Koca, A. F. (2007). Poisoning by mad honey: a brief review. Food and Chemical Toxicology, 45(8), 1315-1318.
  • Kowalski, S., & Makarewicz, M. (2017). Functional properties of honey supplemented with bee bread and propolis. Natural product research, 31(22), 2680-2683.
  • Kujumgiev, A., Tsvetkova, I., Serkedjieva, Y., Bankova, V., Christov, R., & Popov, S. (1999). Antibacterial, antifungal and antiviral activity of propolis of different geographic origin. Journal of ethnopharmacology, 64(3), 235-240.
  • Lad, P. L., & Shier, W. T. (1980). Effect of melittin-induced membrane alterations on rat heart adenylate cyclase activity. Archives of biochemistry and biophysics, 204(2), 418-424.
  • Lee, G., & Bae, H. (2016). Anti-Inflammatory applications of melittin, a major component of bee venom: detailed mechanism of action and adverse effects. Molecules, 21(5), 616.
  • Ledón, N., Casacó, A., González, R., Bracho, J., & Rosado, A. (2002). Assessment of potential dermal and ocular toxicity and allergic properties of an extract of red propolis. Archives of dermatological research, 293(11), 594-596.
  • Lotfy, M. (2006). Biological activity of bee propolis in health and disease. Asian Pac J Cancer Prev, 7(1), 22-31.
  • Mandal, M. D., & Mandal, S. (2011). Honey: its medicinal property and antibacterial activity. Asian Pacific Journal of Tropical Biomedicine, 1(2), 154-160.
  • Marcucci, M. C. (1995). Propolis: chemical composition, biological properties and therapeutic activity. Apidologie, 26(2), 83-99.
  • Marcucci, M. C. (1995). Propolis: chemical composition, biological properties and therapeutic activity. Apidologie, 26(2), 83-99.
  • Mărgăoan R, Mărghitaş LA, Dezmirean DS, Bobiş O, Bonta V, Cătană C, et al. (2017). Comparative Study on Quality Parameters of Royal Jelly, Apilarnil and Queen Bee Larvae Triturate. Bulletin of the University of Agricultural Sciences & Veterinary Medicine Cluj-Napoca. Animal Science & Biotechnologies, 74(1).
  • Menniti‐Ippolito, F., Mazzanti, G., Santuccio, C., Angela Moro, P., Calapai, G., Firenzuoli, F., ... & Raschetti, R. (2008). Surveillance of suspected adverse reactions to natural health products in Italy. Pharmacoepidemiology and drug safety, 17(6), 626-635.
  • Mohammadzadeh, S., Shariatpanahi, M., Hamedi, M., Ahmadkhaniha, R., Samadi, N., & Ostad, S. N. (2007). Chemical composition, oral toxicity and antimicrobial activity of Iranian propolis. Food chemistry, 103(4), 1097-1103.
  • Muz, M.N. (2007). The effects of Apilarnil (Drone bee larvae) administration on growth performance and secondary sex characteristics of male broilers. Uludağ Üniversitesi, Sağlık Bilimleri, Parazitoloji Anabilim Dalı, Doktora tezi.
  • Nagai, T., Nagashima, T., Myoda, T., & Inoue, R. (2004). Preparation and functional properties of extracts from bee bread. Food/nahrung, 48(3), 226-229.
  • Ozkan, K., Sagcan, N., Ozulku, G., Sagdic, O., Toker, O. S., & Muz, M. N. (2018). Bioactive and bioaccessibility characteristics of honeybee pollens collected from different regions of Turkey. Journal of Food Measurement and Characterization, 12(1), 581-587.
  • Özkök, A., D’arcy, B., & Sorkun, K. (2010). Total phenolic acid and total flavonoid content of Turkish pine honeydew honey. Journal of ApiProduct and ApiMedical Science, 2(2), 65-71.
  • Pavel, C. I., Mărghitaş, L. A., Bobiş, O., Dezmirean, D. S., Şapcaliu, A., Radoi, I., & Mădaş, M. N. (2011). Biological activities of royal jelly-review. Scientific Papers Animal Science and Biotechnologies, 44(2), 108-118.
  • Pellati, F., Orlandini, G., Pinetti, D., & Benvenuti, S. (2011). HPLC-DAD and HPLC-ESI-MS/MS methods for metabolite profiling of propolis extracts. Journal of Pharmaceutical and Biomedical Analysis, 55(5), 934-948.
  • Popova, M., Silici, S., Kaftanoglu, O., & Bankova, V. (2005). Antibacterial activity of Turkish propolis and its qualitative and quantitative chemical composition. Phytomedicine, 12(3), 221-228.
  • Qian, W. L., Khan, Z., Watson, D. G., & Fearnley, J. (2008). Analysis of sugars in bee pollen and propolis by ligand exchange chromatography in combination with pulsed amperometric detection and mass spectrometry. Journal of Food Composition and Analysis, 21(1), 78-83.
  • Rady, I., Siddiqui, I. A., Rady, M., & Mukhtar, H. (2017). Melittin, a major peptide component of bee venom, and its conjugates in cancer therapy. Cancer letters, 402, 16-31.
  • Ramadan, M. F., & Al-Ghamdi, A. (2012). Bioactive compounds and health-promoting properties of royal jelly: A review. Journal of functional foods, 4(1), 39-52.
  • Sawicka, D., Car, H., Borawska, M. H., & Nikliński, J. (2012). The anticancer activity of propolis. Folia Histochemica et Cytobiologica, 50(1), 25-37.
  • Schumacher, M. J., Schmidt, J. O., Egen, N. B., & Lowry, J. E. (1990). Quantity, analysis, and lethality of European and Africanized honey bee venoms. The American journal of tropical medicine and hygiene, 43(1), 79-86.
  • Sforcin, J. M., & Bankova, V. (2011). Propolis: is there a potential for the development of new drugs?. Journal of ethnopharmacology, 133(2), 253-260.
  • Son, D. J., Lee, J. W., Lee, Y. H., Song, H. S., Lee, C. K., & Hong, J. T. (2007). Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds. Pharmacology & therapeutics, 115(2), 246-270.
  • Socarras, K., Theophilus, P., Torres, J., Gupta, K., & Sapi, E. (2017). Antimicrobial activity of bee venom and melittin against Borrelia burgdorferi. Antibiotics, 6(4), 31.
  • Sporns, P., Plhak, L., & Friedrich, J. (1992). Alberta honey composition. Food Research International, 25(2), 93-100.
  • Sütlüpmar, N., Mat, A., & Satganoglu, Y. (1993). Poisoning by toxic honey in Turkey. Archives of toxicology, 67(2), 148-150.
  • Szczêsna, T. (2006). Protein content and amino acid composition of bee-collected pollen from selected botanical origins. Journal of Apicultural Science, 50(2), 81-90.
  • Takenaka, T., & Echigo, T. (1980). Chemical composition of royal jelly. Bulletin of the Faculty of Agriculture, Tamagawa University, (20), 71-78.
  • Toreti, V. C., Sato, H. H., Pastore, G. M., & Park, Y. K. (2013). Recent progress of propolis for its biological and chemical compositions and its botanical origin. Evidence-based complementary and alternative medicine, 13.
  • Tosi, E., Ciappini, M., Re, E., & Lucero, H. (2002). Honey thermal treatment effects on hydroxymethylfurfural content. Food Chemistry, 77(1), 71-74.
  • Turhan, K. (2009). Effects of thermal treatment and storage on hydroxymethylfurfural (HMF) content and diastase activity of honeys collected from middle Anatolia in Turkey. In Innovations in Chemical Biology (pp. 233-239). Springer, Dordrecht.
  • Ulusoy, E. (2012) Bal ve apiterapi. Uludağ Arıcılık Dergisi, 2012.
  • Vasquez, A., & Olofsson, T. C. (2009). The lactic acid bacteria involved in the production of bee pollen and bee bread. Journal of apicultural research, 48(3), 189-195.
  • Velikova, M., Bankova, V., Marcucci, M. C., Tsvetkova, I., & Kujumgiev, A. (2000). Chemical composition and biological activity of propolis from Brazilian meliponinae. Zeitschrift für Naturforschung C, 55(9-10), 785-789.
  • Viuda‐Martos, M., Ruiz‐Navajas, Y., Fernández‐López, J., & Pérez‐Álvarez, J. A. (2008). Functional properties of honey, propolis, and royal jelly. Journal of food science, 73(9), R117-R124.
  • Wagh, V. D. (2013). Propolis: a wonder bees product and its pharmacological potentials. Advances in pharmacological sciences, 2013.
  • Walker, P., & Crane, E. (1987). Constituents of propolis. Apidologie, 18(4), 327-334.
  • Weston, R. J., Mitchell, K. R., & Allen, K. L. (1999). Antibacterial phenolic components of New Zealand manuka honey. Food chemistry, 64(3), 295-301.
  • Yucel, B., Acikgoz, Z., Bayraktar, H., & Seremet, C. (2011). The effects of Apilarnil (Drone bee larvae) administration on growth performance and secondary sex characteristics of male broilers. Journal of Animal and Veterinary Advances, 10(17), 2263-2266.
  • Zamami, Y., Takatori, S., Koyama, T., Goda, M., Iwatani, Y., Doi, S., & Kawasaki, H. (2007). Effect of propolis on insulin resistance in fructose-drinking rats. Yakugaku zasshi: Journal of the Pharmaceutical Society of Japan, 127(12), 2065-2073.

BEE PRODUCT and APITHERAPY

Yıl 2019, Cilt: 10 Sayı: 1, 1 - 15, 20.05.2019

Ali Sorucu

Öz

Natural products have been used for health protection and treatment of diseases for thousands of years.
Ancient civilizations such as China, Indian, North American Indians, Egypt and the Sumerians used natural
products against diseases. In recent years, developing drug resistance and side effects that using outside of the
procedure and increase of cancer cases has led to the search for alternative solutions in modern medicine. Bee
products are among the most important alternative treatment method. There are apitherapy centers which diseases
are treated with bee products where China, Russia, Romania and some Eastern European countries. In recent years,
apitherapy studies have started in our country. In 2014, with the regulation of traditional and complementary
medicine practices, apitherapy courses and centers have been started to establish.
Honey, pollen and wax first come to mind in bee products but these products are the visible part of the
iceberg. Apart from these products, honey bee has biologically importance products such as propolis, royal jelly,
apilarnil, bee venom, bee bread (perga), apilarnil and hive air.

Anahtar Kelimeler

Apitherapy Bee venom Honey Pollen Propolis

Kaynakça

  • Akhmetova, R., Sibgatullin, J., Garmonov, S., & Akhmetova, L. (2012). Technology for extraction of bee-bread from the honeycomb. Procedia Engineering, 42, 1822-1825.
  • Al-Mamary, M., Al-Meeri, A., & Al-Habori, M. (2002). Antioxidant activities and total phenolics of different types of honey. Nutrition research, 22(9), 1041-1047.
  • Altan, Ö., Yücel, B., Açikgöz, Z., Şeremet, Ç., Kösoğlu, M., Turgan, N., & Özgönül, A. M. (2013). Apilarnil reduces fear and advances sexual development in male broilers but has no effect on growth. British poultry science, 54(3), 355-361.
  • Amoros, M., Sauvager, F., Girre, L., & Cormier, M. (1992). In vitro antiviral activity of propolis. Apidologie, 23(3), 231-240.
  • Annila, I. (2000). Bee venom allergy. Clinical & Experimental Allergy, 30(12), 1682-1687.
  • Aureli, P., Franciosa, G., & Fenicia, L. (2002). Infant botulism and honey in Europe: a commentary. The Pediatric infectious disease journal, 21(9), 866-868.
  • Aydın L, Doğanay A, Oruç HH, Yeşilbağ K, Bakırcı S, Girişkin O, et al. (2017). Bal Arısı Yetiştiriciliği Ürünleri Hastalıkları. Dora Basım Yayım Dağıtım 2017;1. Baskı:155-90.
  • Bankova, V. S., de Castro, S. L., & Marcucci, M. C. (2000). Propolis: recent advances in chemistry and plant origin. Apidologie, 31(1), 3-15.
  • Banskota, A. H., Tezuka, Y., & Kadota, S. (2001). Recent progress in pharmacological research of propolis. Phytotherapy research, 15(7), 561-571.
  • Bărnuţiu, L. I., Mărghitaş, L., Dezmirean, D., Bobiş, O., Mihai, C., & Pavel, C. (2013). Physicochemical composition of Apilarnil (bee drone larvae). Lucrări Ştiinţifice-Seria Zootehnie, 59, 199-202.
  • Basualdo, M., Barragán, S., & Antúnez, K. (2014). Bee bread increases honeybee haemolymph protein and promote better survival despite of causing higher N osema ceranae abundance in honeybees. Environmental microbiology reports, 6(4), 396-400.
  • Benković, V., Knežević, A., Đikić, D., Lisičić, D., Oršolić, N., Bašić, I., & Kopjar, N. (2009). Radioprotective effects of quercetin and ethanolic extract of propolis in gamma-irradiated mice. Archives of Industrial Hygiene and Toxicology, 60(2), 129-138.
  • Bhandari, B., D'Arcy, B., & Kelly, C. (1999). Rheology and crystallization kinetics of honey: present status. International Journal of Food Properties, 2(3), 217-226.
  • Bogdanov, S., Ruoff, K., & Oddo, L. P. (2004). Physico-chemical methods for the characterisation of unifloral honeys: a review. Apidologie, 35(Suppl. 1), S4-S17.
  • Bogdanov, S., Jurendic, T., Sieber, R., & Gallmann, P. (2008). Honey for nutrition and health: a review. Journal of the American College of Nutrition, 27(6), 677-689.
  • Bogdanov, S. (2009). Honey composition. The honey book, 1-9.
  • Bogdanov, S. (2011a). Pollen: nutrition, functional properties, health: a review. Bee Product Science, 1-34.
  • Bogdanov, S. (2011b). Royal jelly, bee brood: composition, health, medicine: a review. Lipids, 3(8), 8-19.
  • Bogdanov, S. (2011c). Bee Venom: Composition, health. Medicine. A review. Bee Prod Sci, 1-20.
  • Bogdanov, S. (2012a). Honey as nutrient and functional food. Proteins, 1100, 1400-2700.
  • Bogdanov, S. (2012b). Pollen: collection, harvest, composition, quality. The bee pollen book.
  • Bogdanov, S. (2012c). Propolis: biological properties and medical applications. The propolis book, 2:1.
  • Buchta, V., Černý, J., & Opletalová, V. (2011). In vitro antifungal activity of propolis samples of Czech and Slovak origin. Open Life Sciences, 6(2), 160-166.
  • Burdock, G. A. (1998). Review of the biological properties and toxicity of bee propolis (propolis). Food and Chemical toxicology, 36(4), 347-363.
  • Campos, M. G., Bogdanov, S., de Almeida-Muradian, L. B., Szczesna, T., Mancebo, Y., Frigerio, C., & Ferreira, F. (2008). Pollen composition and standardisation of analytical methods. Journal of Apicultural Research, 47(2), 154-161.
  • Cirasino, L., Pisati, A., & Fasani, F. (1987). Contact dermatitis from propolis. Contact dermatitis, 16(2), 110-111.
  • Connor, L.J., Muir, R.G. (2013). Pollen and Bee Bread. Am Bee J,153:727-729.
  • Crane, E., Visscher, P.K. (2009). Honey. Encyclopedia of Insects (Second Edition): Elsevier, p. 459-61.
  • De Castro, S. L. (2001). Propolis: biological and pharmacological activities. Therapeutic uses of this bee-product. Annual Review of Biomedical Sciences, 3, 49-83.
  • de Groot, A. C. (2013). Propolis: a review of properties, applications, chemical composition, contact allergy, and other adverse effects. Dermatitis, 24(6), 263-282.
  • Dempsey, C. E. (1990). The actions of melittin on membranes. Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes, 1031(2), 143-161.
  • Duran, N., Muz, M., Culha, G., Duran, G., & Ozer, B. (2011). GC-MS analysis and antileishmanial activities of two Turkish propolis types. Parasitology research, 108(1), 95-105.
  • El-Ghazaly, M. A., Rashed, R. R., & Khayyal, M. T. (2011). Anti-ulcerogenic effect of aqueous propolis extract and the influence of radiation exposure. International journal of radiation biology, 87(10), 1045-1051.
  • Fallico, B., Zappala, M., Arena, E., & Verzera, A. (2004). Effects of conditioning on HMF content in unifloral honeys. Food Chemistry, 85(2), 305-313.
  • Fu, J. Y., Xia, Y., & Zheng, Y. Y. (2004). Antimutagenicity of propolis against some mutagens in vivo and in vitro. Biomed Environ Sci, 17(4), 469-75.
  • Gauldie, J., HANSON, J. M., RUMJANEK, F. D., SHIPOLINI, R. A., & VERNON, C. A. (1976). The peptide components of bee venom. European journal of biochemistry, 61(2), 369-376.
  • Ghisalberti, E. L. (1979). Propolis: a review. Bee world, 60(2), 59-84.
  • Ginsberg, N. J., Dauer, M., & SLOTTA, K. H. (1968). Melittin used as a protective agent against X-irradiation. Nature, 220(5174), 1334.
  • Giusti, F., Miglietta, R., Pepe, P., & Seidenari, S. (2004). Sensitization to propolis in 1255 children undergoing patch testing. Contact dermatitis, 51(5‐6), 255-258.
  • Gleiter, R. A., Horn, H., & Isengard, H. D. (2006). Influence of type and state of crystallisation on the water activity of honey. Food chemistry, 96(3), 441-445.
  • Gunduz, A., Turedi, S., Uzun, H., & Topbas, M. (2006). Mad honey poisoning. The American journal of emergency medicine, 24(5), 595-598.
  • Hepburn, H. R., Radloff, S. E., Duangphakdee, O., & Phaincharoen, M. (2009). Interspecific utilisation of wax in comb building by honeybees. Naturwissenschaften, 96(6), 719-723.
  • Hepburn, H.R., Pirk, C.W.W., Duangphakdee, O. (2016). Honeybee nests. Springer-Verlag Berlin An.
  • Huang, S., Zhang, C. P., Wang, K., Li, G., & Hu, F. L. (2014). Recent advances in the chemical composition of propolis. Molecules, 19(12), 19610-19632.
  • János, K.R. (2015). Bee Hive Air therapies in Central-Europe. No Bees No Life Apitherapy Symposium 2015;Lukovica and Maribor, Slovenia, 23rd-24th October.
  • Jeng, S. N., Shih, M. K., Kao, C. M., Liu, T. Z., & Chen, S. C. (2000). Antimutagenicity of ethanol extracts of bee glue against environmental mutagens. Food and chemical toxicology, 38(10), 893-897.
  • Khalil, M. I., Sulaiman, S. A., & Boukraa, L. (2010). Antioxidant properties of honey and its role in preventing health disorder. The Open Nutraceuticals Journal, 3(1).
  • Koca, I., & Koca, A. F. (2007). Poisoning by mad honey: a brief review. Food and Chemical Toxicology, 45(8), 1315-1318.
  • Kowalski, S., & Makarewicz, M. (2017). Functional properties of honey supplemented with bee bread and propolis. Natural product research, 31(22), 2680-2683.
  • Kujumgiev, A., Tsvetkova, I., Serkedjieva, Y., Bankova, V., Christov, R., & Popov, S. (1999). Antibacterial, antifungal and antiviral activity of propolis of different geographic origin. Journal of ethnopharmacology, 64(3), 235-240.
  • Lad, P. L., & Shier, W. T. (1980). Effect of melittin-induced membrane alterations on rat heart adenylate cyclase activity. Archives of biochemistry and biophysics, 204(2), 418-424.
  • Lee, G., & Bae, H. (2016). Anti-Inflammatory applications of melittin, a major component of bee venom: detailed mechanism of action and adverse effects. Molecules, 21(5), 616.
  • Ledón, N., Casacó, A., González, R., Bracho, J., & Rosado, A. (2002). Assessment of potential dermal and ocular toxicity and allergic properties of an extract of red propolis. Archives of dermatological research, 293(11), 594-596.
  • Lotfy, M. (2006). Biological activity of bee propolis in health and disease. Asian Pac J Cancer Prev, 7(1), 22-31.
  • Mandal, M. D., & Mandal, S. (2011). Honey: its medicinal property and antibacterial activity. Asian Pacific Journal of Tropical Biomedicine, 1(2), 154-160.
  • Marcucci, M. C. (1995). Propolis: chemical composition, biological properties and therapeutic activity. Apidologie, 26(2), 83-99.
  • Marcucci, M. C. (1995). Propolis: chemical composition, biological properties and therapeutic activity. Apidologie, 26(2), 83-99.
  • Mărgăoan R, Mărghitaş LA, Dezmirean DS, Bobiş O, Bonta V, Cătană C, et al. (2017). Comparative Study on Quality Parameters of Royal Jelly, Apilarnil and Queen Bee Larvae Triturate. Bulletin of the University of Agricultural Sciences & Veterinary Medicine Cluj-Napoca. Animal Science & Biotechnologies, 74(1).
  • Menniti‐Ippolito, F., Mazzanti, G., Santuccio, C., Angela Moro, P., Calapai, G., Firenzuoli, F., ... & Raschetti, R. (2008). Surveillance of suspected adverse reactions to natural health products in Italy. Pharmacoepidemiology and drug safety, 17(6), 626-635.
  • Mohammadzadeh, S., Shariatpanahi, M., Hamedi, M., Ahmadkhaniha, R., Samadi, N., & Ostad, S. N. (2007). Chemical composition, oral toxicity and antimicrobial activity of Iranian propolis. Food chemistry, 103(4), 1097-1103.
  • Muz, M.N. (2007). The effects of Apilarnil (Drone bee larvae) administration on growth performance and secondary sex characteristics of male broilers. Uludağ Üniversitesi, Sağlık Bilimleri, Parazitoloji Anabilim Dalı, Doktora tezi.
  • Nagai, T., Nagashima, T., Myoda, T., & Inoue, R. (2004). Preparation and functional properties of extracts from bee bread. Food/nahrung, 48(3), 226-229.
  • Ozkan, K., Sagcan, N., Ozulku, G., Sagdic, O., Toker, O. S., & Muz, M. N. (2018). Bioactive and bioaccessibility characteristics of honeybee pollens collected from different regions of Turkey. Journal of Food Measurement and Characterization, 12(1), 581-587.
  • Özkök, A., D’arcy, B., & Sorkun, K. (2010). Total phenolic acid and total flavonoid content of Turkish pine honeydew honey. Journal of ApiProduct and ApiMedical Science, 2(2), 65-71.
  • Pavel, C. I., Mărghitaş, L. A., Bobiş, O., Dezmirean, D. S., Şapcaliu, A., Radoi, I., & Mădaş, M. N. (2011). Biological activities of royal jelly-review. Scientific Papers Animal Science and Biotechnologies, 44(2), 108-118.
  • Pellati, F., Orlandini, G., Pinetti, D., & Benvenuti, S. (2011). HPLC-DAD and HPLC-ESI-MS/MS methods for metabolite profiling of propolis extracts. Journal of Pharmaceutical and Biomedical Analysis, 55(5), 934-948.
  • Popova, M., Silici, S., Kaftanoglu, O., & Bankova, V. (2005). Antibacterial activity of Turkish propolis and its qualitative and quantitative chemical composition. Phytomedicine, 12(3), 221-228.
  • Qian, W. L., Khan, Z., Watson, D. G., & Fearnley, J. (2008). Analysis of sugars in bee pollen and propolis by ligand exchange chromatography in combination with pulsed amperometric detection and mass spectrometry. Journal of Food Composition and Analysis, 21(1), 78-83.
  • Rady, I., Siddiqui, I. A., Rady, M., & Mukhtar, H. (2017). Melittin, a major peptide component of bee venom, and its conjugates in cancer therapy. Cancer letters, 402, 16-31.
  • Ramadan, M. F., & Al-Ghamdi, A. (2012). Bioactive compounds and health-promoting properties of royal jelly: A review. Journal of functional foods, 4(1), 39-52.
  • Sawicka, D., Car, H., Borawska, M. H., & Nikliński, J. (2012). The anticancer activity of propolis. Folia Histochemica et Cytobiologica, 50(1), 25-37.
  • Schumacher, M. J., Schmidt, J. O., Egen, N. B., & Lowry, J. E. (1990). Quantity, analysis, and lethality of European and Africanized honey bee venoms. The American journal of tropical medicine and hygiene, 43(1), 79-86.
  • Sforcin, J. M., & Bankova, V. (2011). Propolis: is there a potential for the development of new drugs?. Journal of ethnopharmacology, 133(2), 253-260.
  • Son, D. J., Lee, J. W., Lee, Y. H., Song, H. S., Lee, C. K., & Hong, J. T. (2007). Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds. Pharmacology & therapeutics, 115(2), 246-270.
  • Socarras, K., Theophilus, P., Torres, J., Gupta, K., & Sapi, E. (2017). Antimicrobial activity of bee venom and melittin against Borrelia burgdorferi. Antibiotics, 6(4), 31.
  • Sporns, P., Plhak, L., & Friedrich, J. (1992). Alberta honey composition. Food Research International, 25(2), 93-100.
  • Sütlüpmar, N., Mat, A., & Satganoglu, Y. (1993). Poisoning by toxic honey in Turkey. Archives of toxicology, 67(2), 148-150.
  • Szczêsna, T. (2006). Protein content and amino acid composition of bee-collected pollen from selected botanical origins. Journal of Apicultural Science, 50(2), 81-90.
  • Takenaka, T., & Echigo, T. (1980). Chemical composition of royal jelly. Bulletin of the Faculty of Agriculture, Tamagawa University, (20), 71-78.
  • Toreti, V. C., Sato, H. H., Pastore, G. M., & Park, Y. K. (2013). Recent progress of propolis for its biological and chemical compositions and its botanical origin. Evidence-based complementary and alternative medicine, 13.
  • Tosi, E., Ciappini, M., Re, E., & Lucero, H. (2002). Honey thermal treatment effects on hydroxymethylfurfural content. Food Chemistry, 77(1), 71-74.
  • Turhan, K. (2009). Effects of thermal treatment and storage on hydroxymethylfurfural (HMF) content and diastase activity of honeys collected from middle Anatolia in Turkey. In Innovations in Chemical Biology (pp. 233-239). Springer, Dordrecht.
  • Ulusoy, E. (2012) Bal ve apiterapi. Uludağ Arıcılık Dergisi, 2012.
  • Vasquez, A., & Olofsson, T. C. (2009). The lactic acid bacteria involved in the production of bee pollen and bee bread. Journal of apicultural research, 48(3), 189-195.
  • Velikova, M., Bankova, V., Marcucci, M. C., Tsvetkova, I., & Kujumgiev, A. (2000). Chemical composition and biological activity of propolis from Brazilian meliponinae. Zeitschrift für Naturforschung C, 55(9-10), 785-789.
  • Viuda‐Martos, M., Ruiz‐Navajas, Y., Fernández‐López, J., & Pérez‐Álvarez, J. A. (2008). Functional properties of honey, propolis, and royal jelly. Journal of food science, 73(9), R117-R124.
  • Wagh, V. D. (2013). Propolis: a wonder bees product and its pharmacological potentials. Advances in pharmacological sciences, 2013.
  • Walker, P., & Crane, E. (1987). Constituents of propolis. Apidologie, 18(4), 327-334.
  • Weston, R. J., Mitchell, K. R., & Allen, K. L. (1999). Antibacterial phenolic components of New Zealand manuka honey. Food chemistry, 64(3), 295-301.
  • Yucel, B., Acikgoz, Z., Bayraktar, H., & Seremet, C. (2011). The effects of Apilarnil (Drone bee larvae) administration on growth performance and secondary sex characteristics of male broilers. Journal of Animal and Veterinary Advances, 10(17), 2263-2266.
  • Zamami, Y., Takatori, S., Koyama, T., Goda, M., Iwatani, Y., Doi, S., & Kawasaki, H. (2007). Effect of propolis on insulin resistance in fructose-drinking rats. Yakugaku zasshi: Journal of the Pharmaceutical Society of Japan, 127(12), 2065-2073.
Toplam 91 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Veteriner Bilimleri
Bölüm Derleme
Yazarlar

Ali Sorucu

Yayımlanma Tarihi 20 Mayıs 2019
Kabul Tarihi 2 Şubat 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 10 Sayı: 1

Kaynak Göster

APA Sorucu, A. (2019). ARI ÜRÜNLERİ ve APİTERAPİ. Veteriner Farmakoloji Ve Toksikoloji Derneği Bülteni, 10(1), 1-15.
 Kapak Resmi İndir


  


Creative Commons Lisansı

Bu eser Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı ile lisanslanmıştır.