Derleme
BibTex RIS Kaynak Göster

MACROCYCLIC LACTONES IN THE TREATMENT OF PARASITIC DISEASES IN DOGS AND CATS

Yıl 2023, Cilt: 14 Sayı: 2, 88 - 97, 01.09.2023

Beyza Avcı Kader Yıldız

https://doi.org/10.38137/vftd.1283923

Öz

Macrocyclic lactones are licensed for the treatment of some parasites in dogs and cats. These compounds are also used off-label in the treatment of parasites. The aim of the review was to give information about the use of macrocyclic lactones in dogs and cats parasites.

Anahtar Kelimeler

Macrocyclic lactons dog cat parasite off-label

Kaynakça

  • Arthur, R. G., Bowman, D. D., Slone, R. L. & Travis, L. E. (2005). Imidacloprid plus moxidectin topical solution for the prevention of heartworm disease (Dirofiloria immitis) in dogs. Parasitology Research, 97 (Suppl 1), S76-S80.
  • Bahçivan, E. & Oğuz, H. (2019). Zehirlenmelerde intravenöz lipit emülsiyonu tedavisi. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 12, 70–77.
  • Bates, N., Chatterton, J., Robbins, C., Wells, K., Hughes, J., Stone, M. & Campbell, A. (2013). Lipid infusion in the management of poisoning: a report of 6 canine cases. Veterinary Record, 172, 339.
  • Bishop, B. F., Bruce, C. I., Evans, N. A., Goudie, A. C., Gration, K. A., Gibson, S. P., Pacey, M. S., Perry, D. A., Walshe, N. D. & Witty, M. J. (2000). Selamectin: a novel broad-spectrum endectocide for dogs and cats. Veterinary Parasitology, 91, 163-176.
  • Blagburn, B. L., Hendrix, C. M., Lindsay, D. S. & Vaughan, J. L. (1987). Anthelmintic efficacy of ivermectin in naturally parasitized cats. American Journal of Veterinary Research, 48, 670-672.
  • Blagburn, B. L., Hendrix, C. M., Lindsay, D. S., Vaughan, J. L., Hepler, D. I. & Wright, J. C. (1992). Efficacy of milbemycin oxime against naturally acquired or experimentally induced Ancylostoma spp. and Trichuris vulpis infections in dogs. American Journal of Veterinary Research, 53, 513-516.
  • Bowman, D. D., Lin, D. S., Johnson, R. C. & Hepler, D. I. (1991). Effect of milbemycin oxime on adult Ancylostoma caninum and Uncinaria stenocephala in dogs with experimentally induced infections. American Journal of Veterinary Research, 52, 64-67.
  • Bowman, D. D. (2014). Georgis’ Parasitology for Veterinarians. 10th ed. St Louis Missouri: Elsevier Saunders. Boy, M. G., Six, R. H., Thomas, C. A., Novotny, M. J., Smothers, C. D., Rowan, T. G. & Jernigan, A. D. (2000). Efficacy and safety of selamectin against fleas and heartworms in dogs and cats presented as veterinary patients in North America. Veterinary Parasitology, 91, 233-250.
  • Crandell, D. E. & Weinberg, G. L. (2009). Moxidectin toxicosis in a puppy successfully treated with intravenous lipids. Journal of Veterinary Emergency and Critical Care, 19, 181-186.
  • El-Saber Batiha, G., Alqahtani, A., Ilesanmi, O. B., Saati, A. A., El-Mleeh, A., Hetta, H. F. & Magdy Beshbishy, A. (2020). Avermectin derivatives, pharmacokinetics, therapeutic and toxic dosages, mechanism of action, and their biological effects. Pharmaceuticals (Basel), 13, 196.
  • Geyer, J. & Janko, C. (2012). Treatment of MDR1 mutant dogs with macrocyclic lactones. Current Pharmaceutical Biotechnology, 13, 969-986.
  • Grieve, R. B., Frank, G. R., Stewart, V. A., Parsons, J. C., Belasco, D. L. & Hepler, D. I. (1991). Chemoprophylactic effects of milbemycin oxime against larvae of Dirofilaria immitis during prepatent development. American Journal of Veterinary Research, 52, 2040-2042.
  • Jernigan, A. D., McTier, T. L., Chieffo, C., Thomas, C. A., Krautmann, M. J., Hair, J. A., Young, D. R., Wang, C. & Rowan, T. G. (2000). Efficacy of selamectin against experimentally induced tick (Rhipicephalus sanguineus and Dermacentor variabilis) infestations on dogs. Veterinary Parasitology, 91, 359-375.
  • Johnson-Arbor K. (2022). Ivermectin: a mini-review. Clinic Toxicology (Philadelphia), 60, 571-575. Karademir, Ü. (2005). Köpeklerde ivermektin ve doramektinin ağız ve derialtı yol ile uygulanmalarını takiben karşılaştırılmalı farmakokinetikleri. Yüksek Lisans Tezi, Adnan Menderes Üniversitesi Sağlık Bilimleri Enstitüsü, Aydın.
  • Kidwell, J. H., Buckley, G. J., Allen, A. E. & Bandt, C. (2014). Use of IV lipid emulsion for treatment of ivermectin toxicosis in a cat. Journal of the American Animal Hospital Association, 50, 59-61.
  • Kirkpatrick, C. E. & Megella, C. (1987). Use of ivermectin in treatment of Aelurostrongylus abstrusus and Toxocara cati infections in a cat. Journal of the American Veterinary Medical Association, 190, 1309-1310.
  • Krämer, F., Hammerstein, R., Stoye, M. & Epe C. (2006). Investigations into the prevention of prenatal and lactogenic Toxocara canis infections in puppies by application of moxidectin to the pregnant dog. Journal of Veterinary Medicine B Infectious Diseases and Veterinary Public Health, 53, 218-223.
  • Laing, R., Gillan, V. & Devaney, E. (2017). Ivermectin - old drug, new tricks? Trends in Parasitology, 33, 463-472. Little, S. & Otranto, D. (2019). Tradition and innovation: Selamectin plus sarolaner. A new tool to control endo- and ectoparasites of cats-Studies from North America and Japan. Veterinary Parasitology, 270 Suppl 1, S1-S2.
  • Lok, J. B., Knight, D. H., Selavka, C. M., Eynard, J., Zhang, Y. & Bergman, R. N. (1995). Studies of reproductive competence in male Dirofilaria immitis treated with milbemycin oxime. Tropical Medicine and Parasitology, 46, 235-240.
  • McCall, J. W. (2005). The safety-net story about macrocyclic lactone heartworm preventives: a review, an update, and recommendations. Veterinary Parasitology, 133, 197-206.
  • McKellar, Q. A. & Benchaoui, H. A. (1996). Avermectins and milbemycins. Journal of Veterinary Pharmacology and Therapeutics, 19, 331-351.
  • Mealey, K. L. (2004). Therapeutic implications of the MDR-1 gene. Journal of Veterinary Pharmacology and Therapeutics, 27, 257-264.
  • Mealey, K. L. & Burke, N. S. (2015). Identification of a nonsense mutation in feline ABCB1. Journal of Veterinary Pharmacology and Therapeutics, 38, 429-433.
  • Mealey, K. L. & Meurs, K. M. (2008). Breed distribution of the ABCB1-1Delta (multidrug sensitivity) polymorphism among dogs undergoing ABCB1 genotyping. Journal of the American Veterinary Medical Association, 233, 921-924.
  • Merola, V. M. & Eubig, P. A. (2012). Toxicology of avermectins and milbemycins (macrocylic lactones) and the role of P-glycoprotein in dogs and cats. Veterinary Clinics of North America: Small Animal Practice, 42, 313-333.
  • Merola, V., Khan, S. & Gwaltney-Brant, S. (2009). Ivermectin toxicosis in dogs: a retrospective study. Journal of the American Animal Hospital Association, 45, 106-111.
  • Muhammad, G., Jabbar, A., Khan, M. Z. & Saqib, M. (2004). Use of neostigmine in massive ivermectin toxicity in cats. Veterinary and Human Toxicology, 46, 28-29.
  • Mueller, R. S. (2012). An update on the therapy of canine demodicosis. Compendium: Continuing Education for Veterinarians, 34, E1-4.
  • Nelson, T., McCall, J., Jones, S. & Moorhead, A. (2020). Current Canine Guidelines for the Prevention, Diagnosis, and Management of Heartworm (Dirofilaria immitis) Infection in Dogs. American Heartworm Society Erişim Adresi: AHS_Canine_Guidelines_11_13_20.pdf d3ft8sckhnqim2.cloudfront.net. Erişim Tarihi: 02.12.2022.
  • Parton, K., Wiffen, E. M., Haglund, N. D. & Cave, N. J. (2012). Macrocyclic lactone toxicity due to abamectin in farm dogs without the ABCB1 gene mutation. New Zealand Veterinary Journal, 60, 194-197.
  • Paul, A. J., Tranquilli, W. J. & Hutchens, D. E. (2000). Safety of moxidectin in avermectin-sensitive collies. American Journal of Veterinary Research, 61, 482-483.
  • Perez, R., Cabezas, I., Sutra, J. F., Galtier, P. & Alvinerie, M. (2001). Faecal excretion profile of moxidectin and ivermectin after oral administration in horses. Veterinary Journal, 161, 85-92.
  • Plumb, D. C. (2011). Plumb’s Veterinary Drug Handbook. Seventh Ed. Wiley Blackwell.
  • Pritchard, J. (2010). Treating ivermectin toxicity in cats. Veterinary Record, 166, 766.
  • Prichard, R., Menez, C. & Lespine, A. (2012). Moxidectin and the avermectins: consanguinity but not identity. Internaitonal Journal for Parasitology: Drug and Drug Resistance, 2, 134-153.
  • Tranquilli, W. J., Paul, A. J. & Seward, R. L. (1989). Ivermectin plasma concentrations in collies sensitive to ivermectin-induced toxicosis. American Journal of Veterinary Research, 50, 769-770.
  • Tranquilli, W. J., Paul, A. J., Seward, R. L., Todd, K. S. & Dipietro, J. A. (1987). Response to physostigmine administration in collie dogs exhibiting ivermectin toxicosis. Journal of Veterinary Pharmacology and Terapeutics, 10, 96-100.
  • Vercruysse, J. (2002). Macrocyclic Lactones in Antiparasitic Therapy. Belgium: CABI Publishing.
  • Yarsan, E. & Pehlivan, S. (2020). Veteriner hekimlikte etiket dışı ilaç kullanımı: antimikrobiyal ilaçlar. Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni, 11, 134-150.
  • Wiebe, V. J. & Howard, J. P. (2009). Pharmacologic advances in canine and feline reproduction. Topics in Companion Animal Medicine, 24, 71-99.

KÖPEK VE KEDİDE PARAZİT HASTALIKLARININ TEDAVİSİNDE MAKROSİKLİK LAKTONLAR

Yıl 2023, Cilt: 14 Sayı: 2, 88 - 97, 01.09.2023

Beyza Avcı Kader Yıldız

https://doi.org/10.38137/vftd.1283923

Öz

Makrosiklik laktonlar köpek ve kedide bazı parazitlerin tedavisinde ruhsatlıdır. Bu bileşikler zaman zaman parazit tedavisinde etiket dışı (off-label) da kullanılmaktadır. Bu derlemede makrosiklik laktonların köpek ve kedi parazitlerine kullanımı hakkında bilgi verilmesi amaçlanmıştır.

Anahtar Kelimeler

köpek kedi makrosiklik lakton

Kaynakça

  • Arthur, R. G., Bowman, D. D., Slone, R. L. & Travis, L. E. (2005). Imidacloprid plus moxidectin topical solution for the prevention of heartworm disease (Dirofiloria immitis) in dogs. Parasitology Research, 97 (Suppl 1), S76-S80.
  • Bahçivan, E. & Oğuz, H. (2019). Zehirlenmelerde intravenöz lipit emülsiyonu tedavisi. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 12, 70–77.
  • Bates, N., Chatterton, J., Robbins, C., Wells, K., Hughes, J., Stone, M. & Campbell, A. (2013). Lipid infusion in the management of poisoning: a report of 6 canine cases. Veterinary Record, 172, 339.
  • Bishop, B. F., Bruce, C. I., Evans, N. A., Goudie, A. C., Gration, K. A., Gibson, S. P., Pacey, M. S., Perry, D. A., Walshe, N. D. & Witty, M. J. (2000). Selamectin: a novel broad-spectrum endectocide for dogs and cats. Veterinary Parasitology, 91, 163-176.
  • Blagburn, B. L., Hendrix, C. M., Lindsay, D. S. & Vaughan, J. L. (1987). Anthelmintic efficacy of ivermectin in naturally parasitized cats. American Journal of Veterinary Research, 48, 670-672.
  • Blagburn, B. L., Hendrix, C. M., Lindsay, D. S., Vaughan, J. L., Hepler, D. I. & Wright, J. C. (1992). Efficacy of milbemycin oxime against naturally acquired or experimentally induced Ancylostoma spp. and Trichuris vulpis infections in dogs. American Journal of Veterinary Research, 53, 513-516.
  • Bowman, D. D., Lin, D. S., Johnson, R. C. & Hepler, D. I. (1991). Effect of milbemycin oxime on adult Ancylostoma caninum and Uncinaria stenocephala in dogs with experimentally induced infections. American Journal of Veterinary Research, 52, 64-67.
  • Bowman, D. D. (2014). Georgis’ Parasitology for Veterinarians. 10th ed. St Louis Missouri: Elsevier Saunders. Boy, M. G., Six, R. H., Thomas, C. A., Novotny, M. J., Smothers, C. D., Rowan, T. G. & Jernigan, A. D. (2000). Efficacy and safety of selamectin against fleas and heartworms in dogs and cats presented as veterinary patients in North America. Veterinary Parasitology, 91, 233-250.
  • Crandell, D. E. & Weinberg, G. L. (2009). Moxidectin toxicosis in a puppy successfully treated with intravenous lipids. Journal of Veterinary Emergency and Critical Care, 19, 181-186.
  • El-Saber Batiha, G., Alqahtani, A., Ilesanmi, O. B., Saati, A. A., El-Mleeh, A., Hetta, H. F. & Magdy Beshbishy, A. (2020). Avermectin derivatives, pharmacokinetics, therapeutic and toxic dosages, mechanism of action, and their biological effects. Pharmaceuticals (Basel), 13, 196.
  • Geyer, J. & Janko, C. (2012). Treatment of MDR1 mutant dogs with macrocyclic lactones. Current Pharmaceutical Biotechnology, 13, 969-986.
  • Grieve, R. B., Frank, G. R., Stewart, V. A., Parsons, J. C., Belasco, D. L. & Hepler, D. I. (1991). Chemoprophylactic effects of milbemycin oxime against larvae of Dirofilaria immitis during prepatent development. American Journal of Veterinary Research, 52, 2040-2042.
  • Jernigan, A. D., McTier, T. L., Chieffo, C., Thomas, C. A., Krautmann, M. J., Hair, J. A., Young, D. R., Wang, C. & Rowan, T. G. (2000). Efficacy of selamectin against experimentally induced tick (Rhipicephalus sanguineus and Dermacentor variabilis) infestations on dogs. Veterinary Parasitology, 91, 359-375.
  • Johnson-Arbor K. (2022). Ivermectin: a mini-review. Clinic Toxicology (Philadelphia), 60, 571-575. Karademir, Ü. (2005). Köpeklerde ivermektin ve doramektinin ağız ve derialtı yol ile uygulanmalarını takiben karşılaştırılmalı farmakokinetikleri. Yüksek Lisans Tezi, Adnan Menderes Üniversitesi Sağlık Bilimleri Enstitüsü, Aydın.
  • Kidwell, J. H., Buckley, G. J., Allen, A. E. & Bandt, C. (2014). Use of IV lipid emulsion for treatment of ivermectin toxicosis in a cat. Journal of the American Animal Hospital Association, 50, 59-61.
  • Kirkpatrick, C. E. & Megella, C. (1987). Use of ivermectin in treatment of Aelurostrongylus abstrusus and Toxocara cati infections in a cat. Journal of the American Veterinary Medical Association, 190, 1309-1310.
  • Krämer, F., Hammerstein, R., Stoye, M. & Epe C. (2006). Investigations into the prevention of prenatal and lactogenic Toxocara canis infections in puppies by application of moxidectin to the pregnant dog. Journal of Veterinary Medicine B Infectious Diseases and Veterinary Public Health, 53, 218-223.
  • Laing, R., Gillan, V. & Devaney, E. (2017). Ivermectin - old drug, new tricks? Trends in Parasitology, 33, 463-472. Little, S. & Otranto, D. (2019). Tradition and innovation: Selamectin plus sarolaner. A new tool to control endo- and ectoparasites of cats-Studies from North America and Japan. Veterinary Parasitology, 270 Suppl 1, S1-S2.
  • Lok, J. B., Knight, D. H., Selavka, C. M., Eynard, J., Zhang, Y. & Bergman, R. N. (1995). Studies of reproductive competence in male Dirofilaria immitis treated with milbemycin oxime. Tropical Medicine and Parasitology, 46, 235-240.
  • McCall, J. W. (2005). The safety-net story about macrocyclic lactone heartworm preventives: a review, an update, and recommendations. Veterinary Parasitology, 133, 197-206.
  • McKellar, Q. A. & Benchaoui, H. A. (1996). Avermectins and milbemycins. Journal of Veterinary Pharmacology and Therapeutics, 19, 331-351.
  • Mealey, K. L. (2004). Therapeutic implications of the MDR-1 gene. Journal of Veterinary Pharmacology and Therapeutics, 27, 257-264.
  • Mealey, K. L. & Burke, N. S. (2015). Identification of a nonsense mutation in feline ABCB1. Journal of Veterinary Pharmacology and Therapeutics, 38, 429-433.
  • Mealey, K. L. & Meurs, K. M. (2008). Breed distribution of the ABCB1-1Delta (multidrug sensitivity) polymorphism among dogs undergoing ABCB1 genotyping. Journal of the American Veterinary Medical Association, 233, 921-924.
  • Merola, V. M. & Eubig, P. A. (2012). Toxicology of avermectins and milbemycins (macrocylic lactones) and the role of P-glycoprotein in dogs and cats. Veterinary Clinics of North America: Small Animal Practice, 42, 313-333.
  • Merola, V., Khan, S. & Gwaltney-Brant, S. (2009). Ivermectin toxicosis in dogs: a retrospective study. Journal of the American Animal Hospital Association, 45, 106-111.
  • Muhammad, G., Jabbar, A., Khan, M. Z. & Saqib, M. (2004). Use of neostigmine in massive ivermectin toxicity in cats. Veterinary and Human Toxicology, 46, 28-29.
  • Mueller, R. S. (2012). An update on the therapy of canine demodicosis. Compendium: Continuing Education for Veterinarians, 34, E1-4.
  • Nelson, T., McCall, J., Jones, S. & Moorhead, A. (2020). Current Canine Guidelines for the Prevention, Diagnosis, and Management of Heartworm (Dirofilaria immitis) Infection in Dogs. American Heartworm Society Erişim Adresi: AHS_Canine_Guidelines_11_13_20.pdf d3ft8sckhnqim2.cloudfront.net. Erişim Tarihi: 02.12.2022.
  • Parton, K., Wiffen, E. M., Haglund, N. D. & Cave, N. J. (2012). Macrocyclic lactone toxicity due to abamectin in farm dogs without the ABCB1 gene mutation. New Zealand Veterinary Journal, 60, 194-197.
  • Paul, A. J., Tranquilli, W. J. & Hutchens, D. E. (2000). Safety of moxidectin in avermectin-sensitive collies. American Journal of Veterinary Research, 61, 482-483.
  • Perez, R., Cabezas, I., Sutra, J. F., Galtier, P. & Alvinerie, M. (2001). Faecal excretion profile of moxidectin and ivermectin after oral administration in horses. Veterinary Journal, 161, 85-92.
  • Plumb, D. C. (2011). Plumb’s Veterinary Drug Handbook. Seventh Ed. Wiley Blackwell.
  • Pritchard, J. (2010). Treating ivermectin toxicity in cats. Veterinary Record, 166, 766.
  • Prichard, R., Menez, C. & Lespine, A. (2012). Moxidectin and the avermectins: consanguinity but not identity. Internaitonal Journal for Parasitology: Drug and Drug Resistance, 2, 134-153.
  • Tranquilli, W. J., Paul, A. J. & Seward, R. L. (1989). Ivermectin plasma concentrations in collies sensitive to ivermectin-induced toxicosis. American Journal of Veterinary Research, 50, 769-770.
  • Tranquilli, W. J., Paul, A. J., Seward, R. L., Todd, K. S. & Dipietro, J. A. (1987). Response to physostigmine administration in collie dogs exhibiting ivermectin toxicosis. Journal of Veterinary Pharmacology and Terapeutics, 10, 96-100.
  • Vercruysse, J. (2002). Macrocyclic Lactones in Antiparasitic Therapy. Belgium: CABI Publishing.
  • Yarsan, E. & Pehlivan, S. (2020). Veteriner hekimlikte etiket dışı ilaç kullanımı: antimikrobiyal ilaçlar. Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni, 11, 134-150.
  • Wiebe, V. J. & Howard, J. P. (2009). Pharmacologic advances in canine and feline reproduction. Topics in Companion Animal Medicine, 24, 71-99.
Toplam 40 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Veteriner Bilimleri
Bölüm Derleme
Yazarlar

Beyza Avcı 0000-0002-0434-4471

Kader Yıldız 0000-0001-5802-6156

Yayımlanma Tarihi 1 Eylül 2023
Kabul Tarihi 3 Temmuz 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 14 Sayı: 2

Kaynak Göster

APA Avcı, B., & Yıldız, K. (2023). KÖPEK VE KEDİDE PARAZİT HASTALIKLARININ TEDAVİSİNDE MAKROSİKLİK LAKTONLAR. Veteriner Farmakoloji Ve Toksikoloji Derneği Bülteni, 14(2), 88-97. https://doi.org/10.38137/vftd.1283923
 Kapak Resmi İndir


  


Creative Commons Lisansı

Bu eser Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı ile lisanslanmıştır.