Abstract
Despite having a low fatality rate in monkeys, monkeypox remains an important disease because of its zoonotic potential. The aim of this study is to describe the clinical, pathological, ultrastructural and virological findings of the first monkeypox case diagnosed in a baby monkey in Türkiye with unknown transmission. A monkeypox infection was detected in a 1-month-old, female, baby monkey born in Antalya Zoo and died with skin lesions. It was reported that the baby's mother did not care for and caregivers took care of the cub, and skin lesions on the hands of the caregivers and responsible veterinarian were reported. Necropsy, histopathology, electron microscopy and chorioallantoic membrane (CAM) test were performed. Typical cutaneous and pulmonary poxvirus finding in a baby monkey was described in this case. CAM results firstly reported in a monkeypox case. Because of the zoonotic potential of illness, monkey colonies, particularly in zoos, must be controlled with vigilance. This is the first monkeypox report in a baby monkey in Türkiye.
Ethical Statement
There is ethical approval for this study.
Thanks
This case report was presented in 2020 at the X. National and I. International Congress of Veterinary Pathology in Burdur, Türkiye. From the Ministry of Agriculture and Forestry's General Directorate of Nature Conservation and National Parks, R.T. Official authorization "E-21264211-288.04 [Biodiversity Research Permits]-1380321 dated 05.05.2021 and Research Permit" was received for this study.
References
- Alakunle E, Moens U, Nchinda G, et al (2020): Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution. Viruses, 12, 1257.
- Arita I, Henderson D (1968): Smallpox and monkeypox in non-human primates. Bull World Health Organ, 39, 277–283.
- Cho CT, Wenner HA (1973): Monkeypox virus. Bacteriol Rev, 37, 1–18.
- Hobson G, Adamson J, Adler H, et al (2021): Family cluster of three cases of monkeypox imported from Nigeria to the United Kingdom, May 2021. Euro Surveill, 26, 2100745.
- Hutson CL, Carroll DS, Gallardo-Romero N, et al (2015): Comparison of Monkeypox Virus clade kinetics and pathology within the prairie dog animal model using a serial sacrifice study design. Biomed Res Int, 2015, 965710.
- Khodakevich L, Szczeniowski M, Manbu-ma-Disu, et al (1987): The role of squirrels in sustaining monkeypox virus transmission. Trop Geogr Med, 39, 115–122.
- Macneil A, Reynolds MG, Braden Z, et al (2009): Transmission of atypical varicella-zoster virus infections involving palm and sole manifestations in an area with monkeypox endemicity. Clin Infect Dis, 48, e6–8.
- Prier J, Sauer R (1960): A pox disease of monkeys. Ann N Y Acad Sci, 85, 951–959.
- von Magnus P, Andersen E, Petersen K, et al (1959): A pox-like disease in cynomolgus monkeys. Acta Pathol Microbiol Scand, 46,156–176.
- Zaucha GM, Jahrling PB, Geisbert TW, et al (2001): The pathology of experimental aerosolized Monkeypox Virus infection in Cynomolgus Monkeys (Macaca fascicularis). Lab Invest, 81, 581–600.
Abstract
References
- Alakunle E, Moens U, Nchinda G, et al (2020): Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution. Viruses, 12, 1257.
- Arita I, Henderson D (1968): Smallpox and monkeypox in non-human primates. Bull World Health Organ, 39, 277–283.
- Cho CT, Wenner HA (1973): Monkeypox virus. Bacteriol Rev, 37, 1–18.
- Hobson G, Adamson J, Adler H, et al (2021): Family cluster of three cases of monkeypox imported from Nigeria to the United Kingdom, May 2021. Euro Surveill, 26, 2100745.
- Hutson CL, Carroll DS, Gallardo-Romero N, et al (2015): Comparison of Monkeypox Virus clade kinetics and pathology within the prairie dog animal model using a serial sacrifice study design. Biomed Res Int, 2015, 965710.
- Khodakevich L, Szczeniowski M, Manbu-ma-Disu, et al (1987): The role of squirrels in sustaining monkeypox virus transmission. Trop Geogr Med, 39, 115–122.
- Macneil A, Reynolds MG, Braden Z, et al (2009): Transmission of atypical varicella-zoster virus infections involving palm and sole manifestations in an area with monkeypox endemicity. Clin Infect Dis, 48, e6–8.
- Prier J, Sauer R (1960): A pox disease of monkeys. Ann N Y Acad Sci, 85, 951–959.
- von Magnus P, Andersen E, Petersen K, et al (1959): A pox-like disease in cynomolgus monkeys. Acta Pathol Microbiol Scand, 46,156–176.
- Zaucha GM, Jahrling PB, Geisbert TW, et al (2001): The pathology of experimental aerosolized Monkeypox Virus infection in Cynomolgus Monkeys (Macaca fascicularis). Lab Invest, 81, 581–600.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Pathology, Veterinary Virology |
| Journal Section | Case Report |
| Authors | |
| Publication Date | September 29, 2023 |
| Published in Issue | Year 2023 |