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Mesothelioma in a dog

Year 2012, , 151 - 153, 01.06.2012
https://doi.org/10.1501/Vetfak_0000002518

Abstract

In this study a mesothelioma case observed in a four–year-old female Rottweiler dog was defined. Macroscopically, on the serosal surfaces of the stomach and intestines, numerous masses showing diffuse distribution, greyish yellow in colour and hard consistency were observed. Microscopically, tumour cells were predominantly spindle-shaped with moderate amounts of eosinophilic cytoplasm and ovoid nuclei. These cells was not stained with epithelial membrane antigen (EMA) staining, the epithelial marker, while stained with the epithelial marker pancytokeratin and mesenchymal marker vimentin in the avidin-biotin-peroxidase (ABC-P) method. As a result, tumor case seen in a dog's stomach and intestinal serosal surface was defined as a mesothelioma according to the histopathological and immunohistochemical findings

References

  • Amaya JO, Arevalo GH (2008): Invasive Mesothelioma of Canine: Cytology, Clinical and Pathology’s Findings. Int J Morphol, 1, 103-112
  • Attanoos RL, Dojcinov SD, Webb R, Gibbs AR (2000): Anti-mesothelial markers in sarcomatoid mesothelioma and other spindle cell neoplasms. Histopathology, 37, 224–231.
  • Avakian A, Alroy J, Rozanski E, Keating J, Rosenberg A (2008): Lipid-rich pleural mesothelioma in a dog. J Vet Diagn Invest, 5, 665-667.
  • Bacci B, Morandi F, De Meo M, Marcato PS (2006): Ten cases of feline mesothelioma: an immunohistochemical and ultrastructural study. J Comp Pathol, 134, 347–354.
  • Bollo E, Scaglione FE, Tursi . M, Schröder C, Degiorgi G, Belluso E, Capella S, Bellis D (2010): Malignant pleural mesothelioma in a female Lion (Panthera leo) Res Vet Sci, doi:10.1016/ jrvsc. 2010.08.005
  • Cacciotti P, Libener R, Betta P, Martini F, Porta C, Procopio A, Strizzi L, Penengo L, Tognon M, Mutti L, Gaudino G (2001): SV40 replication in human mesothelial cells induces HGF/Met receptor activation: a model for viral-related carcinogenesis of human malignant mesotelioma. Proc Nati Acad Sci, 98, 12032- 12037.
  • Caswell J, Wiliams K (2007): Respiratory system M. Maxie (ed) 5th (Ed), Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals, 5th edition, Elsevier, New York, NY, USA, p. 523–655.
  • Croft W (1983): Environmental asbestos and mesotheliomas in dairy calves. Proc Am Assoc Cancer Res, 24, 188.
  • Gibbs GW, Berry G (2008): Mesothelioma and asbestos. Regul Toxicol Pharmacol, 52, 223–31.
  • Head KW, Else RW, Dubielzig RR (2002): Tumours of the alimentary tract. D.J. Meuten (ed.) Tumours In Domestic Animals, p. 401-481.
  • Kim JH, Choi YK, Yoon HY, Kweon OK, Kim DY (2002): Juvenile malignant mesotelioma in a dog. J Vet Med Sci, 64, 269-271.
  • Ledecka K, Sevcikova Z, Mihaly M, Hajurka J, Pavuk V, Hluchy M, Skurkova L, Lackova M, Ledecky V (2010) Mesothelioma of the pericardium in a Bernese Mesothelioma of the pericardium in a Bernese mountain dog. Veterinarski Arhıv, 80, 797-806.
  • Presnell JK, Schreibman MP (1997): Humason’s Animal Tissue Techniques.. In: Presnell J., Schreibman M.P (ed.), 5th (Ed), The Johns Hopkins University Press. Ltd, London, p. 269-312.
  • Vural SA, Ozyildiz Z, Ozsoy SY (2007): Pleural mesothelioma in a nine month-old dog. Irish Vet J, 1, 30- 33.
  • Yamate J, Tomita A, Kuwamura M, Mitsunaga F, Nakamura S (2007): Spontaneous peritoneal malignant mesothelioma in a geriatric japanese macaque (Macaca fuscata). Exp Anim, 56, 155–159.

Köpekte mezotelioma olgusu

Year 2012, , 151 - 153, 01.06.2012
https://doi.org/10.1501/Vetfak_0000002518

Abstract

Bu çalışmada 4 yaşlı Rottweiler ırkı, dişi bir köpekte gözlenen mezotelioma olgusu tanımlandı. Makroskobik olarak mide ve bağırsakların serozal yüzeyinde diffuz dağılım gösteren, değişik büyüklükte ve sert kıvamda, grimsi sarı renkte kitleler görüldü. Mikroskobik olarak tümör hücreleri çoğunlukla iğ şeklinde, eozinofilik sitoplazmalı ovoid çekirdekliydi. Bu hücreler uygulanan avidin biyotin peroksidaz (ABC-P) immunohistokimyasal boyama yönteminde, epiteliyal belirteç pansitokeratin ve mezenkimal belirteç vimentin ile boyanırken epiteliyal belirteç olan epitheliyal membran antijeni (EMA) ile boyanmadı. Sonuç olarak bir köpeğin mide ve bağırsak serozal yüzeyinde karşılaşılan tümör olgusu, histopatolojik ve immunohistokimyasal bulgularına göre mesotelioma olarak tanımlandı

References

  • Amaya JO, Arevalo GH (2008): Invasive Mesothelioma of Canine: Cytology, Clinical and Pathology’s Findings. Int J Morphol, 1, 103-112
  • Attanoos RL, Dojcinov SD, Webb R, Gibbs AR (2000): Anti-mesothelial markers in sarcomatoid mesothelioma and other spindle cell neoplasms. Histopathology, 37, 224–231.
  • Avakian A, Alroy J, Rozanski E, Keating J, Rosenberg A (2008): Lipid-rich pleural mesothelioma in a dog. J Vet Diagn Invest, 5, 665-667.
  • Bacci B, Morandi F, De Meo M, Marcato PS (2006): Ten cases of feline mesothelioma: an immunohistochemical and ultrastructural study. J Comp Pathol, 134, 347–354.
  • Bollo E, Scaglione FE, Tursi . M, Schröder C, Degiorgi G, Belluso E, Capella S, Bellis D (2010): Malignant pleural mesothelioma in a female Lion (Panthera leo) Res Vet Sci, doi:10.1016/ jrvsc. 2010.08.005
  • Cacciotti P, Libener R, Betta P, Martini F, Porta C, Procopio A, Strizzi L, Penengo L, Tognon M, Mutti L, Gaudino G (2001): SV40 replication in human mesothelial cells induces HGF/Met receptor activation: a model for viral-related carcinogenesis of human malignant mesotelioma. Proc Nati Acad Sci, 98, 12032- 12037.
  • Caswell J, Wiliams K (2007): Respiratory system M. Maxie (ed) 5th (Ed), Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals, 5th edition, Elsevier, New York, NY, USA, p. 523–655.
  • Croft W (1983): Environmental asbestos and mesotheliomas in dairy calves. Proc Am Assoc Cancer Res, 24, 188.
  • Gibbs GW, Berry G (2008): Mesothelioma and asbestos. Regul Toxicol Pharmacol, 52, 223–31.
  • Head KW, Else RW, Dubielzig RR (2002): Tumours of the alimentary tract. D.J. Meuten (ed.) Tumours In Domestic Animals, p. 401-481.
  • Kim JH, Choi YK, Yoon HY, Kweon OK, Kim DY (2002): Juvenile malignant mesotelioma in a dog. J Vet Med Sci, 64, 269-271.
  • Ledecka K, Sevcikova Z, Mihaly M, Hajurka J, Pavuk V, Hluchy M, Skurkova L, Lackova M, Ledecky V (2010) Mesothelioma of the pericardium in a Bernese Mesothelioma of the pericardium in a Bernese mountain dog. Veterinarski Arhıv, 80, 797-806.
  • Presnell JK, Schreibman MP (1997): Humason’s Animal Tissue Techniques.. In: Presnell J., Schreibman M.P (ed.), 5th (Ed), The Johns Hopkins University Press. Ltd, London, p. 269-312.
  • Vural SA, Ozyildiz Z, Ozsoy SY (2007): Pleural mesothelioma in a nine month-old dog. Irish Vet J, 1, 30- 33.
  • Yamate J, Tomita A, Kuwamura M, Mitsunaga F, Nakamura S (2007): Spontaneous peritoneal malignant mesothelioma in a geriatric japanese macaque (Macaca fuscata). Exp Anim, 56, 155–159.
There are 15 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Other ID JA96FJ69NH
Journal Section Research Article
Authors

Kübra A. Kapakin Terim

Rıfkı Hazıroğlu

Nesrin Gürsan

Gözde Yücel

Publication Date June 1, 2012
Published in Issue Year 2012

Cite

APA Terim, K. A. K., Hazıroğlu, R., Gürsan, N., Yücel, G. (2012). Mesothelioma in a dog. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 59(2), 151-153. https://doi.org/10.1501/Vetfak_0000002518
AMA Terim KAK, Hazıroğlu R, Gürsan N, Yücel G. Mesothelioma in a dog. Ankara Univ Vet Fak Derg. June 2012;59(2):151-153. doi:10.1501/Vetfak_0000002518
Chicago Terim, Kübra A. Kapakin, Rıfkı Hazıroğlu, Nesrin Gürsan, and Gözde Yücel. “Mesothelioma in a Dog”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 59, no. 2 (June 2012): 151-53. https://doi.org/10.1501/Vetfak_0000002518.
EndNote Terim KAK, Hazıroğlu R, Gürsan N, Yücel G (June 1, 2012) Mesothelioma in a dog. Ankara Üniversitesi Veteriner Fakültesi Dergisi 59 2 151–153.
IEEE K. A. K. Terim, R. Hazıroğlu, N. Gürsan, and G. Yücel, “Mesothelioma in a dog”, Ankara Univ Vet Fak Derg, vol. 59, no. 2, pp. 151–153, 2012, doi: 10.1501/Vetfak_0000002518.
ISNAD Terim, Kübra A. Kapakin et al. “Mesothelioma in a Dog”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 59/2 (June 2012), 151-153. https://doi.org/10.1501/Vetfak_0000002518.
JAMA Terim KAK, Hazıroğlu R, Gürsan N, Yücel G. Mesothelioma in a dog. Ankara Univ Vet Fak Derg. 2012;59:151–153.
MLA Terim, Kübra A. Kapakin et al. “Mesothelioma in a Dog”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, vol. 59, no. 2, 2012, pp. 151-3, doi:10.1501/Vetfak_0000002518.
Vancouver Terim KAK, Hazıroğlu R, Gürsan N, Yücel G. Mesothelioma in a dog. Ankara Univ Vet Fak Derg. 2012;59(2):151-3.