Abstract
Bu çalışmada, klinik olarak yemede güçlük ve aşırı salivasyon görülen, 4 yaşlı, dişi bir kedinin sağ alt dudağında apokrin duktal karsinoma olgusu tanımlandı. Tümöral kitle makroskobik olarak, 7 gr ağırlığında, 6x3x2 cm boyutlarında, üzeri deriyle kaplı olup fluktuan kıvamlıydı. Kesit yüzü incelendiğinde ise içlerinde kahverengi-sarı renkte mukoid içeriğin olduğu çok sayıda kistik yapılar görüldü. Sitolojik olarak, kümeler halinde dizilim gösteren, polihedral şekilli, geniş ve vakuollü sitoplazmalı, oval, hiperkromatik çekirdekli anaplazik özellikler gösteren epitel hücreleri dikkati çekti. Histolojik olarak, kas demetlerinin aralarında, iri, hiperkromatik çekirdekli, belirgin eozinofilik sitoplazmalı, tek sıralı, anaplazik bez epitelleriyle döşeli bez yapılarının genişlediği ve lumene doğru papillar uzantılar verdiği görüldü. Bazı bezler arasında tek sıralı epitel hücreleriyle döşeli, kistik bezlere rastlandı. Bu bezlerin lumenlerinde ise eozinofilik salgı ve bunların arasında ise kanama alanları ile mononüklear hücre infiltrasyonu saptandı
Keywords
References
- Aslan S (2008): Örtü epiteli. 117-134. In: A. Özer (ed), Veteriner Özel Histoloji. 1. Baskı. Nobel Yayın Dağıtım, Ankara.
- Goldschmidt MH, Hendrick MJ (2002): Tumors of the Skin and Soft Tissues. 70-73. In: DJ Meuton, (ed), Tumors in Domestic Animals. 4 th ed. Iowa State Press, Iowa.
- Herráez P, Rodríguez F, Ramírez G, Aguirre- Sanceledonio M, Castro A, Espinosa de los Monteros A (2005): Multiple primary digital apocrine sweat gland carcinosarcoma in a cat. Vet Rec, 157, 356-358.
- Nibe K, Uchida K, Itoh T, Tateyama S (2005): A case of canine apocrine sweat gland adenoma, clear cell variant. Vet Pathol, 42, 215-218.
- Simko E, Wilcock BP, Yager JA ( 2003): A retrospective study of 44 canine apocrine sweat gland adenocarcinomas. Can Vet J, 44, 38-42.
- Urayama F, Sato T, Shibuya H, Shirai W, Metsutani M, Yamazaki R (2001): Apocrine adenocarcinoma in a golden hamster. J Vet Med Sci, 63, 1249-1252.
- Weiss E, Frese K (1974): Tumours of the skin. 82. In: BULLETIN of the World Health Organization, International Histological Classification of Tumours of Domestic Animals. WHO, Geneve.
Abstract
In the study, ductal carcinoma was described in labium inferior of a 4 years-old female cat, which reffered to clinics with the complaints of difficulty in eating anorexia and hypersalivation. Macroscopically, the mass was covered with skin and sized in 6x3x2 cm, weighed of 7 gr and fluctuant. There were multiple cysts and brownish-yellow mucinous secret in cutting surfaces. In cytopathological examination; anaplastic ductal epithelial cell, having polihedral shaped, elongated-hypochromatic nuclei and vacuolated cytoplasm, were attended. Histopathologically, neoplastic ductal epithelia showing large-hyperchromatic nuclei and eosinophilic cytoplasm was arreged glands among muscle cells. It was noted that the glands were dilated and developed papillary proliferations into lumen. Cysts were covered with flattened epitheliums and filled with secret in lumens. In interglandular areas, hemorrhagia and mononuclear cells were observed
Keywords
References
- Aslan S (2008): Örtü epiteli. 117-134. In: A. Özer (ed), Veteriner Özel Histoloji. 1. Baskı. Nobel Yayın Dağıtım, Ankara.
- Goldschmidt MH, Hendrick MJ (2002): Tumors of the Skin and Soft Tissues. 70-73. In: DJ Meuton, (ed), Tumors in Domestic Animals. 4 th ed. Iowa State Press, Iowa.
- Herráez P, Rodríguez F, Ramírez G, Aguirre- Sanceledonio M, Castro A, Espinosa de los Monteros A (2005): Multiple primary digital apocrine sweat gland carcinosarcoma in a cat. Vet Rec, 157, 356-358.
- Nibe K, Uchida K, Itoh T, Tateyama S (2005): A case of canine apocrine sweat gland adenoma, clear cell variant. Vet Pathol, 42, 215-218.
- Simko E, Wilcock BP, Yager JA ( 2003): A retrospective study of 44 canine apocrine sweat gland adenocarcinomas. Can Vet J, 44, 38-42.
- Urayama F, Sato T, Shibuya H, Shirai W, Metsutani M, Yamazaki R (2001): Apocrine adenocarcinoma in a golden hamster. J Vet Med Sci, 63, 1249-1252.
- Weiss E, Frese K (1974): Tumours of the skin. 82. In: BULLETIN of the World Health Organization, International Histological Classification of Tumours of Domestic Animals. WHO, Geneve.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Other ID | JA63FE66UJ |
| Journal Section | Research Article |
| Authors | |
| Publication Date | March 1, 2011 |
| Published in Issue | Year 2011 |