Case Report
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Year 2020, , 427 - 430, 01.09.2020
https://doi.org/10.33988/auvfd.566781

Abstract

References

  • 1. Allan K, Masters N, Rivers S, et al (2014): T-lymphocyte-rich thymoma and myasthenia gravis in a siberian tiger (Panthera tigris altaica). J Comp Pathol, 150, 345-349.
  • 2. Andres KM, Kent M, Siedlecki CT, et al (2012): The use of megavoltage radiation therapy in the treatment of thymomas in rabbits: 19 cases. Vet Comp Oncol, 10, 82-94.
  • 3. Boddu P, Thakral B, Alhuraiji A, et al (2019): Distinguishing thymoma from T-lymphoblastic leukaemia/lymphoma: a case-based evaluation. J Clin Pathol, 72, 251-257.
  • 4. Ertel V, Früh A, Guenther A, et al (2013): Thymoma with molecularly verified “conversion” to T lymphoblastic leukemia/lymphoma over 9 years. Leuk Lymphoma, 54, 2765-2768.
  • 5. Florizoone K, van der Luer R, van den Ingh T (2017): Symmetrical alopecia, scaling and hepatitis in a rabbit. Vet Dermatol, 18, 161-164.
  • 6. Gupta BN (1976): Lymphosarcoma in a rabbit. Am J Vet Res, 37, 841-843.
  • 7. Ito J, Yoshida A, Maeshima AM, et al (2015): Concurrent thymoma, thymic carcinoma, and T lymphoblastic leukemia/lymphoma in an anterior mediastinal mass. Pathol Res Pract, 211, 693-696.
  • 8. Jacobs R, Messick J, Valli V (2008): Tumors of the hemolymphatic system. 119-198. In: DJ Meuten (Ed), Tumors in Domestic Animals. Blackwell Publishing, Iowa.
  • 9. Macon WR, Rynalski TH, Swerdlow SH, et al (1991): T-cell lymphoblastic leukemia/lymphoma presenting in a recurrent thymoma. Mod Pathol, 4, 524-528.
  • 10. Nishioka R, Nakajima S, Morimoto Y, et al (1995): T-cell acute lymphoblastic leukemia with transient pure red cell aplasia associated with myasthenia gravis and invasive thymoma. Intern Med, 34, 127-130.
  • 11. Pliny AA, Reavill D (2008): Chylothorax and thymic lymphoma in a pet rabbit (Oryctolagus cuniculus). J Exot Pet Med, 17, 295-299.
  • 12. Suster S, Moran CA (2006): Thymoma classification: current status and future trends. Am J Clin Pathol, 125, 542-554.
  • 13. Travis WD, Brambilla E, Muller-Hermelink HK, et al (2004): World Health Organization International Histological Classification of Tumours. Pathology and Genetics of Tumors of the Lung, Pleura, Thymus and Heart. IARC Press, Lyon.
  • 14. Valli VEO, Gentry PA (1993): The Hematopoietic System. 109-324. In: KVF Jubb, PC Kennedy, N Palmer (Eds), Pathology of Domestic Animals. Academic Press, New York.
  • 15. Wakely Jr, PE (2005): Cytopathology of thymic epithelial neoplasms. Semin Diagn Pathol, 22, 213-222.

A case of thymic lymphoma in a rabbit

Year 2020, , 427 - 430, 01.09.2020
https://doi.org/10.33988/auvfd.566781

Abstract

A five-year-old male rabbit was presented with the request of necropsy. Post mortem examination revealed a mass in the cranial mediastinum. Histopathologically, it was seen that the mass consisted of a limited mesenchymal tissue with medium-sized mature lymphocytes and a large proportion (approximately 90%) of lymphoblast-like round cell infiltration. While tumour cells were stained positively for CD3, they were negative for CD79a. Pan-Cytokeratin was localized in small number of epithelial cells in the background. Histopathological and immunohistochemical evaluation showed that the case was compatible with thymic lymphoma and it was the first case reported in rabbits in Turkey.

References

  • 1. Allan K, Masters N, Rivers S, et al (2014): T-lymphocyte-rich thymoma and myasthenia gravis in a siberian tiger (Panthera tigris altaica). J Comp Pathol, 150, 345-349.
  • 2. Andres KM, Kent M, Siedlecki CT, et al (2012): The use of megavoltage radiation therapy in the treatment of thymomas in rabbits: 19 cases. Vet Comp Oncol, 10, 82-94.
  • 3. Boddu P, Thakral B, Alhuraiji A, et al (2019): Distinguishing thymoma from T-lymphoblastic leukaemia/lymphoma: a case-based evaluation. J Clin Pathol, 72, 251-257.
  • 4. Ertel V, Früh A, Guenther A, et al (2013): Thymoma with molecularly verified “conversion” to T lymphoblastic leukemia/lymphoma over 9 years. Leuk Lymphoma, 54, 2765-2768.
  • 5. Florizoone K, van der Luer R, van den Ingh T (2017): Symmetrical alopecia, scaling and hepatitis in a rabbit. Vet Dermatol, 18, 161-164.
  • 6. Gupta BN (1976): Lymphosarcoma in a rabbit. Am J Vet Res, 37, 841-843.
  • 7. Ito J, Yoshida A, Maeshima AM, et al (2015): Concurrent thymoma, thymic carcinoma, and T lymphoblastic leukemia/lymphoma in an anterior mediastinal mass. Pathol Res Pract, 211, 693-696.
  • 8. Jacobs R, Messick J, Valli V (2008): Tumors of the hemolymphatic system. 119-198. In: DJ Meuten (Ed), Tumors in Domestic Animals. Blackwell Publishing, Iowa.
  • 9. Macon WR, Rynalski TH, Swerdlow SH, et al (1991): T-cell lymphoblastic leukemia/lymphoma presenting in a recurrent thymoma. Mod Pathol, 4, 524-528.
  • 10. Nishioka R, Nakajima S, Morimoto Y, et al (1995): T-cell acute lymphoblastic leukemia with transient pure red cell aplasia associated with myasthenia gravis and invasive thymoma. Intern Med, 34, 127-130.
  • 11. Pliny AA, Reavill D (2008): Chylothorax and thymic lymphoma in a pet rabbit (Oryctolagus cuniculus). J Exot Pet Med, 17, 295-299.
  • 12. Suster S, Moran CA (2006): Thymoma classification: current status and future trends. Am J Clin Pathol, 125, 542-554.
  • 13. Travis WD, Brambilla E, Muller-Hermelink HK, et al (2004): World Health Organization International Histological Classification of Tumours. Pathology and Genetics of Tumors of the Lung, Pleura, Thymus and Heart. IARC Press, Lyon.
  • 14. Valli VEO, Gentry PA (1993): The Hematopoietic System. 109-324. In: KVF Jubb, PC Kennedy, N Palmer (Eds), Pathology of Domestic Animals. Academic Press, New York.
  • 15. Wakely Jr, PE (2005): Cytopathology of thymic epithelial neoplasms. Semin Diagn Pathol, 22, 213-222.
There are 15 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section Case Report
Authors

Ayhan Atasever 0000-0002-6327-1604

Duygu Yaman Gram 0000-0003-2404-0384

Görkem Ekebaş 0000-0001-9094-677X

Publication Date September 1, 2020
Published in Issue Year 2020

Cite

APA Atasever, A., Yaman Gram, D., & Ekebaş, G. (2020). A case of thymic lymphoma in a rabbit. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 67(4), 427-430. https://doi.org/10.33988/auvfd.566781
AMA Atasever A, Yaman Gram D, Ekebaş G. A case of thymic lymphoma in a rabbit. Ankara Univ Vet Fak Derg. September 2020;67(4):427-430. doi:10.33988/auvfd.566781
Chicago Atasever, Ayhan, Duygu Yaman Gram, and Görkem Ekebaş. “A Case of Thymic Lymphoma in a Rabbit”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 67, no. 4 (September 2020): 427-30. https://doi.org/10.33988/auvfd.566781.
EndNote Atasever A, Yaman Gram D, Ekebaş G (September 1, 2020) A case of thymic lymphoma in a rabbit. Ankara Üniversitesi Veteriner Fakültesi Dergisi 67 4 427–430.
IEEE A. Atasever, D. Yaman Gram, and G. Ekebaş, “A case of thymic lymphoma in a rabbit”, Ankara Univ Vet Fak Derg, vol. 67, no. 4, pp. 427–430, 2020, doi: 10.33988/auvfd.566781.
ISNAD Atasever, Ayhan et al. “A Case of Thymic Lymphoma in a Rabbit”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 67/4 (September 2020), 427-430. https://doi.org/10.33988/auvfd.566781.
JAMA Atasever A, Yaman Gram D, Ekebaş G. A case of thymic lymphoma in a rabbit. Ankara Univ Vet Fak Derg. 2020;67:427–430.
MLA Atasever, Ayhan et al. “A Case of Thymic Lymphoma in a Rabbit”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, vol. 67, no. 4, 2020, pp. 427-30, doi:10.33988/auvfd.566781.
Vancouver Atasever A, Yaman Gram D, Ekebaş G. A case of thymic lymphoma in a rabbit. Ankara Univ Vet Fak Derg. 2020;67(4):427-30.