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Determination of aflatoxin M1 levels in goat milk consumed in Kilis province

Year 2007, , 99 - 103, 01.06.2007

Mehmet Özdemir

https://doi.org/10.1501/Vetfak_0000000261
Cited By: 1

Abstract

Aflatoxin M1 (AFM1) may occur in milk and dairy products, resulting from the ingestion of feedstuffs contaminated with aflatoxin B1 (AFB1) by dairy goats. The aim of this study was to determine the levels of AFM1 in goat milk commonly consumed in the city of Kilis. One hundred and tensamples of milk were collected randomly from individual farms in Kilis from March 2006 to April 2006, Turkey, samples were analysed for AFM1 by ELISA. AFM1 was not determined in 17 samples (15.46%), whereas 93 samples (84.54%) were found to contain AFM1 at various levels. In 70 of the 110 samples, the presence of AFM1 was detected in a concentration ranging between 5.16 and 116.78 ng/l. AFM1 levels in 7 (6.36%) of 110 goat milk samples were found to be higher than the maximum tolerable limit (50 ng/l) accepted by the Turkish Food Codex. We concluded that AFM1was determined in 84.54% of the goat milk samples consumed by the people in the Kilis province. Moreover 6.36% of samples contained AFM1 at hazardous levels for human health

Keywords

Aflatoxin M1 ELISA goat milk Kilis

References

  • Alborzi S, Pourabbas B, Rashidi M, Astaneh B (2006): Aflatoxin M1 contamination in pasteurized milk in Shiraz (south of Iran). Food Control, 17, 582-584.
  • Aycicek H, Aksoy A, Saygi S (2005): Determination of aflatoxin levels in some dairy and food products which consumed in Ankara, Turkey. Food Control, 16, 263–266.
  • Aycicek H, Yarsan E, Sarımehmetoglu B, Cakmak O (2002): Aflatoxin M1 in white cheese and butter consumed in Istanbul, Turkey. Vet Hum Toxicol, 44, 295-296.
  • Bakirci I (2001): A study on the occurrence of aflatoxin M1 in milk and milk products produced in Van province of Turkey. Food Control, 12, 47–51.
  • Barbieri G, Bergamini C, Ori E, Pesca P (1994): Aflatoxin M1 in Parmesan cheese: HPLC determination. J Food Sci, 59, 1313–1331.
  • Betina V (1989): Aflatoxins, sterigmatocystins and versicolorins. 114-150. Mycotoxins: Chemical, Biological and Environmental Aspects. New York.
  • Codex Alimentarius Commissions (2001): Comments submitted on the draft maximum level for Aflatoxin M1 in milk. Codex Committee on Food Additives and Contaminants 33rd sessions, Hauge, The Netherlands.
  • Cullen JM, Ruebner BH, Hsieh LS, Hyde DM, Hsieh DPH(1987): Carcinogenicity of dietary Aflatoxin M1 in male Fischer rats composed to Aflatoxin B1. Cancer Res, 47, 1913–1917.
  • De Sylos CM, Rodriguez-Amaya DB, Carvalho PRN (1996): Occurrence of aflatoxin M1 in milk and dairy products commercialized in Campinas, Brazil. Food Addit Contam, 13, 169–172.
  • Elgerbi AM, Aidoo KE, Candlish AAG, Tester RF (2004): Occurrence of aflatoxin M1 in randomly selected North African milk and cheese samples. Food Addit Contam, 21, 592–597.
  • Galvano F, Galofaro V, De Angelis A, Galvano M, Bognanno M, Galvano G (1998): Survey of the occurrence of aflatoxin M1 in dairy products marketed in Italy. J Food Prot, 61, 738-741.
  • Galvano F, Galofaro V, Galvano G (1996): Occurrence and stability of aflatoxin M1 in milk and milk products: a worldwide review. J Food Prot, 59, 1079–1090.
  • Galvano F, Galofaro V, Ritieni A, Bognanno M, De Angelis A, Galvano G (2001): Survey of the occurrence of aflatoxin M1 in dairy products marketed in Italy: second year of observation. Food Addit Contam, 18, 644–646.
  • Gürbay A, Aydın S, Girgin G, Engin AB, Şahin G (2006): Assessment of aflatoxin M1 levels in milk in Ankara, Turkey. Food Control, 17, 1-4.
  • IARC (International Agency for Research on Cancer) (1993): Aflatoxins. Some Naturally Occurring Substances: Food Items and Constituents, Heterocyclic aromatic amines and Mycotoxins. 245-395. IARC Monographs on the Evaluation of Carcinogenic Risk to Humans.
  • Kamkar A (2005): A study on the occurrence of aflatoxin M1 in raw milk produced in Sarab city of Iran. Food Control, 16, 593-599.
  • Kaniou-Grigoriadou I, Eleftheriadou A, Mouratidou T, Katikou P (2005): Determination of aflatoxin M1 in ewe’s milk samples and the produced curd and Feta cheese. Food Control, 16, 257-261.
  • Kaya S (2002): Mikotoksinler. 544-568. Veteriner Hekimliğinde Toksikoloji. İkinci Baskı. S Kaya, İ Pirinçci, A Bilgili (Ed), Medisan Yayınevi. Ankara.
  • Kim EE, Shon DH, Ryu D, Park JW, Hwang HJ, Kim YB (2000): Occurrence of aflatoxin M1 in Korean dairy products determined by ELISA and HPLC. Food Addit Contam, 17, 59-64.
  • López CE, Ramos, LL, Ramadán SS, Bulacio LC (2003): Presence of aflatoxin M1 in milk for human consumption in Argentina. Food Control, 14, 31–34.
  • Martins ML, Martins HM (2000): Aflatoxin M1 in raw and ultra high temperature-treated milk commercialized in Portugal. Food Addit Contam, 17, 871-874.
  • Nakajima M, Tabata S, Akiyama H, Itoh Y, Tanaka T, Sunagawa H, Tyonan T, Yoshizawa T, Kumagai S (2004): Occurrence of aflatoxin M1 in domestic milk in Japan during the winter season. Food Addit Contam, 21, 472-478.
  • Oruç HH, Sonal S (2001): Determination of aflatoxin M1 levels in cheese and milk consumed in Bursa, Turkey. Vet Hum Toxicol, 43, 292–293.
  • Park DI (2002): Effect of processing on aflatoxin. Adv Exp Med Biol, 504, 173-179.
  • Pittet A (1998): Natural occurrence of mycotoxins in foods and feeds-an update review. Rev Med Vet, 149, 479- 492.
  • Rastogi S, Dwivedi PD, Khanna SK, Das M (2004): Detection of aflatoxin M1 contamination in milk and infant milk products from Indian markets by ELISA. Food Control, 15, 287–290.
  • Stoloff L (1989): Aflatoxin M1 in perspective. J Food Prot, 43, 226-230.
  • Stoloff L, Van Egmond HP, Parks DL (1991): Rationales for the establishment of limits and regulations for mycotoxins. Food Addit Contam, 8, 222–231.
  • Türk Gıda Kodeksi Tebliğ (2002): Türk Gıda Kodeksi gıda maddelerinde belirli bulaşanların maksimum seviyelerinin belirlenmesi hakkında tebliğ (No:2002/63). Resmi Gazete, 23.09.2002, Sayı: 24885.
  • Van Egmond HP (1989): Aflatoxin M1: occurrence, toxicity, regulation. 11-55. Mycotoxins in Dairy Products. In H.P. Van Egmond (Ed), Elsevier Applied Science, New York.
  • Zar JH (1984): Biostatical Analysis. 2nd ed. Prentice-Hall International (UK) Limited. London. Geliş tarihi: 07.04.2006 / Kabul tarihi: 21.09.2006 Address for correspondance Yard.Doç.Dr. Mehmet Özdemir Afyon Kocatepe Üniversitesi Veteriner Fakültesi Farmakoloji ve Toksikoloji Anabilim Dalı Ahmet Necdet Sezer Kampusü, 03200, Afyonkarahisar e-mail: mozdemir@aku.edu.tr

Kilis bölgesinde tüketilen keçi sütlerinde aflatoksin M1 düzeylerinin belirlenmesi

Year 2007, , 99 - 103, 01.06.2007

Mehmet Özdemir

https://doi.org/10.1501/Vetfak_0000000261
Cited By: 1

Abstract

AFB1 ile kontamine yemler süt keçileri tarafından tüketildiğinde, süt ve süt ürünlerinde AFM1 meydana gelebilir. Bu çalışmanın amacı Kilis’te yaygın olarak tüketilen keçi sütlerindeki AFM1 düzeylerini belirlemektir. 2006 yılı Mart-Nisan aylarında, Kilis’teki bireysel çiftliklerden elde edilen 110 keçi sütü örneklerinde ELISA yöntemiyle AFM1 analizleri yapıldı. AFM1 17 (%15,46) örnekte belirlenemezken, 93 (%84,54) süt örneğinde farklı düzeylerde bulundu. AFM1 110 süt örneğinin 70’inde 5,16–116,78 ng/l düzeyleri arasındaki yoğunluklarda belirlendi. Örneklerin 7’sinde (%6,36) belirlenen AFM1 düzeyleri Türk Gıda Kodeksi’nde belirtilen maksimum kabul edilebilir limitten (50 ng/l) daha yüksek düzeyde ölçüldü. Sonuç olarak, Kilis ilinde insanlar tarafından tüketilen keçi sütü örneklerinin %84,54’ünde AFM1 belirlendi ancak örneklerin %6,36’sı insan sağlığı için risk oluşturacak düzeyde AFM1 içermekteydi

Keywords

Aflatoksin M1 ELISA keçi sütü Kilis

References

  • Alborzi S, Pourabbas B, Rashidi M, Astaneh B (2006): Aflatoxin M1 contamination in pasteurized milk in Shiraz (south of Iran). Food Control, 17, 582-584.
  • Aycicek H, Aksoy A, Saygi S (2005): Determination of aflatoxin levels in some dairy and food products which consumed in Ankara, Turkey. Food Control, 16, 263–266.
  • Aycicek H, Yarsan E, Sarımehmetoglu B, Cakmak O (2002): Aflatoxin M1 in white cheese and butter consumed in Istanbul, Turkey. Vet Hum Toxicol, 44, 295-296.
  • Bakirci I (2001): A study on the occurrence of aflatoxin M1 in milk and milk products produced in Van province of Turkey. Food Control, 12, 47–51.
  • Barbieri G, Bergamini C, Ori E, Pesca P (1994): Aflatoxin M1 in Parmesan cheese: HPLC determination. J Food Sci, 59, 1313–1331.
  • Betina V (1989): Aflatoxins, sterigmatocystins and versicolorins. 114-150. Mycotoxins: Chemical, Biological and Environmental Aspects. New York.
  • Codex Alimentarius Commissions (2001): Comments submitted on the draft maximum level for Aflatoxin M1 in milk. Codex Committee on Food Additives and Contaminants 33rd sessions, Hauge, The Netherlands.
  • Cullen JM, Ruebner BH, Hsieh LS, Hyde DM, Hsieh DPH(1987): Carcinogenicity of dietary Aflatoxin M1 in male Fischer rats composed to Aflatoxin B1. Cancer Res, 47, 1913–1917.
  • De Sylos CM, Rodriguez-Amaya DB, Carvalho PRN (1996): Occurrence of aflatoxin M1 in milk and dairy products commercialized in Campinas, Brazil. Food Addit Contam, 13, 169–172.
  • Elgerbi AM, Aidoo KE, Candlish AAG, Tester RF (2004): Occurrence of aflatoxin M1 in randomly selected North African milk and cheese samples. Food Addit Contam, 21, 592–597.
  • Galvano F, Galofaro V, De Angelis A, Galvano M, Bognanno M, Galvano G (1998): Survey of the occurrence of aflatoxin M1 in dairy products marketed in Italy. J Food Prot, 61, 738-741.
  • Galvano F, Galofaro V, Galvano G (1996): Occurrence and stability of aflatoxin M1 in milk and milk products: a worldwide review. J Food Prot, 59, 1079–1090.
  • Galvano F, Galofaro V, Ritieni A, Bognanno M, De Angelis A, Galvano G (2001): Survey of the occurrence of aflatoxin M1 in dairy products marketed in Italy: second year of observation. Food Addit Contam, 18, 644–646.
  • Gürbay A, Aydın S, Girgin G, Engin AB, Şahin G (2006): Assessment of aflatoxin M1 levels in milk in Ankara, Turkey. Food Control, 17, 1-4.
  • IARC (International Agency for Research on Cancer) (1993): Aflatoxins. Some Naturally Occurring Substances: Food Items and Constituents, Heterocyclic aromatic amines and Mycotoxins. 245-395. IARC Monographs on the Evaluation of Carcinogenic Risk to Humans.
  • Kamkar A (2005): A study on the occurrence of aflatoxin M1 in raw milk produced in Sarab city of Iran. Food Control, 16, 593-599.
  • Kaniou-Grigoriadou I, Eleftheriadou A, Mouratidou T, Katikou P (2005): Determination of aflatoxin M1 in ewe’s milk samples and the produced curd and Feta cheese. Food Control, 16, 257-261.
  • Kaya S (2002): Mikotoksinler. 544-568. Veteriner Hekimliğinde Toksikoloji. İkinci Baskı. S Kaya, İ Pirinçci, A Bilgili (Ed), Medisan Yayınevi. Ankara.
  • Kim EE, Shon DH, Ryu D, Park JW, Hwang HJ, Kim YB (2000): Occurrence of aflatoxin M1 in Korean dairy products determined by ELISA and HPLC. Food Addit Contam, 17, 59-64.
  • López CE, Ramos, LL, Ramadán SS, Bulacio LC (2003): Presence of aflatoxin M1 in milk for human consumption in Argentina. Food Control, 14, 31–34.
  • Martins ML, Martins HM (2000): Aflatoxin M1 in raw and ultra high temperature-treated milk commercialized in Portugal. Food Addit Contam, 17, 871-874.
  • Nakajima M, Tabata S, Akiyama H, Itoh Y, Tanaka T, Sunagawa H, Tyonan T, Yoshizawa T, Kumagai S (2004): Occurrence of aflatoxin M1 in domestic milk in Japan during the winter season. Food Addit Contam, 21, 472-478.
  • Oruç HH, Sonal S (2001): Determination of aflatoxin M1 levels in cheese and milk consumed in Bursa, Turkey. Vet Hum Toxicol, 43, 292–293.
  • Park DI (2002): Effect of processing on aflatoxin. Adv Exp Med Biol, 504, 173-179.
  • Pittet A (1998): Natural occurrence of mycotoxins in foods and feeds-an update review. Rev Med Vet, 149, 479- 492.
  • Rastogi S, Dwivedi PD, Khanna SK, Das M (2004): Detection of aflatoxin M1 contamination in milk and infant milk products from Indian markets by ELISA. Food Control, 15, 287–290.
  • Stoloff L (1989): Aflatoxin M1 in perspective. J Food Prot, 43, 226-230.
  • Stoloff L, Van Egmond HP, Parks DL (1991): Rationales for the establishment of limits and regulations for mycotoxins. Food Addit Contam, 8, 222–231.
  • Türk Gıda Kodeksi Tebliğ (2002): Türk Gıda Kodeksi gıda maddelerinde belirli bulaşanların maksimum seviyelerinin belirlenmesi hakkında tebliğ (No:2002/63). Resmi Gazete, 23.09.2002, Sayı: 24885.
  • Van Egmond HP (1989): Aflatoxin M1: occurrence, toxicity, regulation. 11-55. Mycotoxins in Dairy Products. In H.P. Van Egmond (Ed), Elsevier Applied Science, New York.
  • Zar JH (1984): Biostatical Analysis. 2nd ed. Prentice-Hall International (UK) Limited. London. Geliş tarihi: 07.04.2006 / Kabul tarihi: 21.09.2006 Address for correspondance Yard.Doç.Dr. Mehmet Özdemir Afyon Kocatepe Üniversitesi Veteriner Fakültesi Farmakoloji ve Toksikoloji Anabilim Dalı Ahmet Necdet Sezer Kampusü, 03200, Afyonkarahisar e-mail: mozdemir@aku.edu.tr
There are 31 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section Research Article
Authors

Mehmet Özdemir

Publication Date June 1, 2007
Published in Issue Year 2007

Cite

APA Özdemir, M. (2007). Determination of aflatoxin M1 levels in goat milk consumed in Kilis province. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 54(2), 99-103. https://doi.org/10.1501/Vetfak_0000000261
AMA Özdemir M. Determination of aflatoxin M1 levels in goat milk consumed in Kilis province. Ankara Univ Vet Fak Derg. June 2007;54(2):99-103. doi:10.1501/Vetfak_0000000261
Chicago Özdemir, Mehmet. “Determination of Aflatoxin M1 Levels in Goat Milk Consumed in Kilis Province”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 54, no. 2 (June 2007): 99-103. https://doi.org/10.1501/Vetfak_0000000261.
EndNote Özdemir M (June 1, 2007) Determination of aflatoxin M1 levels in goat milk consumed in Kilis province. Ankara Üniversitesi Veteriner Fakültesi Dergisi 54 2 99–103.
IEEE M. Özdemir, “Determination of aflatoxin M1 levels in goat milk consumed in Kilis province”, Ankara Univ Vet Fak Derg, vol. 54, no. 2, pp. 99–103, 2007, doi: 10.1501/Vetfak_0000000261.
ISNAD Özdemir, Mehmet. “Determination of Aflatoxin M1 Levels in Goat Milk Consumed in Kilis Province”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 54/2 (June 2007), 99-103. https://doi.org/10.1501/Vetfak_0000000261.
JAMA Özdemir M. Determination of aflatoxin M1 levels in goat milk consumed in Kilis province. Ankara Univ Vet Fak Derg. 2007;54:99–103.
MLA Özdemir, Mehmet. “Determination of Aflatoxin M1 Levels in Goat Milk Consumed in Kilis Province”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, vol. 54, no. 2, 2007, pp. 99-103, doi:10.1501/Vetfak_0000000261.
Vancouver Özdemir M. Determination of aflatoxin M1 levels in goat milk consumed in Kilis province. Ankara Univ Vet Fak Derg. 2007;54(2):99-103.

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