Abstract
In this study, ten healthy dogs and twenty with diarrhea at the age of 2-6 months old, totally thirty dogs, from various breeds and sexes were used. The severity of the disease classification and dehydration status in diarrheic dogs were evaluated according to the clinical examination criterias. PH, PCO2, PO2, BE and HCO-3 values using blood gase analyzer and TCO2 values using Harleco analyzer were determined in venous blood samples taken before therapy (0. hour) and at the 24th, 48 th and 72 th hours after therapy in dogs with diarrhea and once in healthy dogs. Changing in acid-base status in dogs with diarrhea were evaluated. Intravenous Ringer’s lactated solution was administered in order to meet the fluid demand and correct the metabolic acidosis. As a result, it was found that micro CO2 system was a practical and reliabl method for determination of TCO2 and Ringer’s lactated solution was able to use for correction of metabolic acidosis and dehydration in dogs with diarrhea
References
- Boothe DM (1999): Emetics and antiemetics. Vet Clin North Am Small Anim Pract, 29, 343-376.
- Carlson GP (1997): Fluid, electrolyt, and acid-base balance. 485-516. In: JJ Kaneko, JW Harvey, ML Bruss (Ed), Clinical Biochemistry of Domestic Animals. Fifth edition, Academic press, London, Boston.
- Conover WJ (1999): Practical non parametric statistics. 3th, Wiley series, Bristhone.
- Davis LE (1981): Sodium bicarbonate and bicarbonate precursors for treatment of metabolic acidosis. JAVMA, 179, 914-916.
- Dibartola SP (1992): Introduction to acid-base disorders. 193-215. In: SP Dibartola (Ed), Fluid Therapy in Small Animal Practice. W.B. Saunders Comp. Philadelphia, London.
- Didwania A, Miller J, Kassel D, Jackson EV, Chernow B (1997): Effect of intravenous lactated ringer’s solution infusion on the circulating lactate concentration: Part 3. Results of a prospective, randomized, double-blind, placebo-controlled trial. Crit Care Med, 25, 1851-1854.
- Guilford WG, Strombeck DR (1996): Fluid therapy of gastrointestinal disease. 911-921. In: WG Guilford, DR Strombeck (Ed), Strombeck’s Small Animal Gastroenterology. W.B. Saunders Comp, Philedelphia.
- Heald RD, Jones BD, Schmidt DA (1986): Blood gase and electrolyte concentrations in canine parvoviral enteritis. J Am Hosp Assoc, 22, 745-748.
- Hyneck M L (1993): Simple acid base disorders. Am J Hos Pharm, 42, 1992-2004.
- Jacobs RM, Weiser MG, Hall RL (1980): Clinicopathologic findings of canine parvoviral enteritis. J Am Anim Hosp Assoc, 16, 809-814.
- Michell AR (1979): The pathophysiological basis of fluid therapy in small animals. Vet Rec, 16, 542-548.
- Mclaughlin ML, Kassirer J (1990): Rational treatment of acid base disorders. Drugs, 36, 841-855.
- Orsini JA (1989): Pathophysiology, diagnosis, and treatment of clinical acid-base disorders. Cont Ed, 11, 593-601.
- Öcal N (1999): Total Parenteral Beslemenin Parvoviral Hemorajik Gastroenteritisli Köpeklerin Sağaltımına Etkisi. Doktora Tezi, Ankara Üniversitesi. Sağlık Bilimleri Ensti- tüsü, s 98.
- Robertson SA (1989): Simple acid base disorders. Vet Clin North Am Small Anim Pract, 19, 289-306.
- Rudloff E, Kirby R (1998): Fluid therapy. crystallloids and colloids. Vet Clin North Am Small Anim Pract, 28, 297-328.
- Sherding RG (1989): Diseases of the small bowel. 1323- 1396. In: SJ Ettinger (Ed), Textbook of Veterinary Internal Medicine. 3th, WB Saunders Company, London, Toronto.
- Sümbüloğlu K, Sümbüloğlu V (2000): Biyoistatitatik. Hatiboğlu Basım ve Yayın San. Tic.Ltd. Şti., Şahin Mat- baası, Ankara.
- Turgut K, Ok M (2001): Diyare ile karakterize hastalık- lar. 283-420. Kedi ve Köpek Gastroenterolojisi Semptom- dan Teşhise. Konya, Bahcıvanlar Basım Sanayi A.Ş. Geliş tarihi: 22.09.2005 / Kabul tarihi: 08.11.2005
Abstract
Bu çalışmada farklı ırk ve cinsiyette 2-6 aylık 20 ishalli ve 10 sağlıklı olmak üzere toplam 30 köpek kullanıldı. İshalli köpeklerde hastalığın şiddetinin sınıflandırılması ve dehidrasyon durumu klinik muayene kriterlerine göre belirlendi. Sağlıklı köpeklerden bir kez, ishalli köpeklerden ise sağaltım öncesi (0. saat) ve sağaltım sonrası 24., 48. ve 72. saatlerde alınan venöz kan örneklerinden kan gazı analizörü kullanılarak pH, PCO, PO2, BE ve HCO-3; de metabolik asit-baz durumundaki değişiklikler değerlendirildi. Sıvı elektrolit gereksinimini karşılamak ve metabolik asidozisi düzeltmek için laktatlı Ringer solüsyonu iv (intravenöz) uygulandı. Sonuç olarak ishalli köpeklerde TCO2 değerinin belirlenmesinde mikro CO2 sisteminin pratik ve güvenilir bir yöntem olduğu ve laktatlı Ringer solüsyonunun metabolik asidozisin düzeltilmesi ile dehidrasyonun giderilmesinde kullanılabileceği kanısına varıldı
References
- Boothe DM (1999): Emetics and antiemetics. Vet Clin North Am Small Anim Pract, 29, 343-376.
- Carlson GP (1997): Fluid, electrolyt, and acid-base balance. 485-516. In: JJ Kaneko, JW Harvey, ML Bruss (Ed), Clinical Biochemistry of Domestic Animals. Fifth edition, Academic press, London, Boston.
- Conover WJ (1999): Practical non parametric statistics. 3th, Wiley series, Bristhone.
- Davis LE (1981): Sodium bicarbonate and bicarbonate precursors for treatment of metabolic acidosis. JAVMA, 179, 914-916.
- Dibartola SP (1992): Introduction to acid-base disorders. 193-215. In: SP Dibartola (Ed), Fluid Therapy in Small Animal Practice. W.B. Saunders Comp. Philadelphia, London.
- Didwania A, Miller J, Kassel D, Jackson EV, Chernow B (1997): Effect of intravenous lactated ringer’s solution infusion on the circulating lactate concentration: Part 3. Results of a prospective, randomized, double-blind, placebo-controlled trial. Crit Care Med, 25, 1851-1854.
- Guilford WG, Strombeck DR (1996): Fluid therapy of gastrointestinal disease. 911-921. In: WG Guilford, DR Strombeck (Ed), Strombeck’s Small Animal Gastroenterology. W.B. Saunders Comp, Philedelphia.
- Heald RD, Jones BD, Schmidt DA (1986): Blood gase and electrolyte concentrations in canine parvoviral enteritis. J Am Hosp Assoc, 22, 745-748.
- Hyneck M L (1993): Simple acid base disorders. Am J Hos Pharm, 42, 1992-2004.
- Jacobs RM, Weiser MG, Hall RL (1980): Clinicopathologic findings of canine parvoviral enteritis. J Am Anim Hosp Assoc, 16, 809-814.
- Michell AR (1979): The pathophysiological basis of fluid therapy in small animals. Vet Rec, 16, 542-548.
- Mclaughlin ML, Kassirer J (1990): Rational treatment of acid base disorders. Drugs, 36, 841-855.
- Orsini JA (1989): Pathophysiology, diagnosis, and treatment of clinical acid-base disorders. Cont Ed, 11, 593-601.
- Öcal N (1999): Total Parenteral Beslemenin Parvoviral Hemorajik Gastroenteritisli Köpeklerin Sağaltımına Etkisi. Doktora Tezi, Ankara Üniversitesi. Sağlık Bilimleri Ensti- tüsü, s 98.
- Robertson SA (1989): Simple acid base disorders. Vet Clin North Am Small Anim Pract, 19, 289-306.
- Rudloff E, Kirby R (1998): Fluid therapy. crystallloids and colloids. Vet Clin North Am Small Anim Pract, 28, 297-328.
- Sherding RG (1989): Diseases of the small bowel. 1323- 1396. In: SJ Ettinger (Ed), Textbook of Veterinary Internal Medicine. 3th, WB Saunders Company, London, Toronto.
- Sümbüloğlu K, Sümbüloğlu V (2000): Biyoistatitatik. Hatiboğlu Basım ve Yayın San. Tic.Ltd. Şti., Şahin Mat- baası, Ankara.
- Turgut K, Ok M (2001): Diyare ile karakterize hastalık- lar. 283-420. Kedi ve Köpek Gastroenterolojisi Semptom- dan Teşhise. Konya, Bahcıvanlar Basım Sanayi A.Ş. Geliş tarihi: 22.09.2005 / Kabul tarihi: 08.11.2005
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Article |
| Authors | |
| Publication Date | June 1, 2006 |
| Published in Issue | Year 2006 |