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The investigation of the plasma monocyte chemoattractant protein-1 and interleukin-1α levels and the relationship between these levels and number of blood lymphocytes and monocytes in calves with foot and mouth disease

Year 2006, , 91 - 95, 01.06.2006

Fatma Gül Yarım Cevat Nisbet Naci Öcal Gülay Çiftçi Aydın Coşkuner

https://doi.org/10.1501/Vetfak_0000000079

Abstract

: In this study, detection of plasma monocyte chemoattractant protein-1 (MCP-1) and interleukin-1 (IL-1α) levels
and correlations between these levels and blood lymphocyte and monocyte numbers was aimed. 1-1.5 years old 16 calves with foot
and mouth disease and 11 calves with healthy were used in study. The levels of MCP-1 and IL-1α in plasma were found to be
significantly increased in calves with foot and mouth disease compared to healthy group (p<0.001). Between the plasma MCP-1 and
IL-1α levels and blood lymphocyte and monocyte numbers were determined to be significantly correlated (p<0.01) in calves with
foot and mouth disease. In the present study, the number of blood lymphocytes and monocytes was positively correlated with plasma
MCP-1 and IL-1α concentrations that suggests MCP-1 and IL-1α are involved in etiopathogenesis of foot and mouth disease

Keywords

Calf foot and mouth disease IL-1α lymphocyte MCP-1 monocyte

References

  • Aderka D, Holtmann H, Toker L, Hahn T, Wallach D (1986): Tumor necrosis factor induction by Sendai virus. J Immunol, 136, 2938-2342.
  • Apte RN, Voronov E (2002): Interleukin-1--a major pleiotropic cytokine in tumor-host interactions. Semin Cancer Biol, 12, 277-290.
  • Baggiolini M, Dewald B, Moser B (1997): Human chemokines: an update. Annu Rev Immunol, 15, 675-705.
  • Boring L, Gosling J, Cleary M, Charo IF (1998): Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature, 394, 894– 897.
  • Breen EC, Rezai K, Nakajima K, Beall GN, Mitsuyasu RT, Hirano T, Kishimoto T, Martinez-Maza O (1990): Infection with HIV is associated with elevated IL-6 levels and production. J Immunol, 144, 480-484.
  • Bubfeld D, Kaufmann A, Meyer RG, Gemsa D, Sprenger H (1998): Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated ınfluenza A virus. Cell Immun, 186, 1-7.
  • Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM (1990): Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci USA, 87, 5134-5138.
  • Davies C (1994): Principles. In The Immunoassay Handbook. D. Wild, ed. Stockton Press, New York, p. 3- 47.
  • Dinarello CA (1996): Biologic basis for interleukin-1 in disease. Blood, 87, 2095-2147.
  • Dinter Z, Morein B (1990): Virus Infections of Ruminants, Elsevier Science Publishers B.V. p. 506-508.
  • Dunphy J, Horvath A, Barcham G, Balic A, Bischof R, Meeusen E (2001): Isolation, characterisation and expression of mRNAs encoding the ovine CC chemokines, monocyte chemoattractant protein (MCP)-1alpha and -2. Vet Immunol Immunopathol, 82, 153-164.
  • Eckersall PD (2000): Recent advances and future pros- pects for the use of acute phase proteins as markers of dis- ease in animals. Revue Med Vet, 151, 577-584.
  • England JM, Rowan RM, van Assendelft OW, Coulter WH, Groner W, Jones AR, Koepke JA, Lewis SM, Shinton NK, Thom R (1984): Protocol for evaluation of automated blood cell counters. International Committee for Standardization in Haematology (ICSH). Clin Lab Haematol, 6, 269-84.
  • Gangur V, Birmingham NP, Thanesvorakul S (2002): Chemokines in health and disease. Vet Immunol Immunopathol, 86, 127-136.
  • Gu L, Tseng S, Rollins BJ (1999): Monocyte chemoattractant protein-1. Chem Immunol, 72, 7– 29.
  • Horadagoda NU, Knox KM, Gibbs HA, Reid SW, Horadagoda A, Edwards SE, Eckersall PD (1999): Acute phase proteins in cattle: discrimination between acute and chronic inflammation. Vet Rec, 17, 144, 437- 441.
  • Imhof BA, Dunon D (1995): Leukocyte migration and adhesion. Adv Immunol, 58, 345-416.
  • Janeway CA, Medzhitov R (2002): Innate immune rec- ognition. Annu Rev Immunol, 20, 197-216.
  • Kuby J (1997): Immunology, 3rd Ed., WH Freeman and Co, New York.
  • Lechner F, Machado J, Bertoni G, Seow HF, Dobbelaere DA, Peterhans E (1997): Caprine arthritis encephalitis virus dysregulates the expression of cytokines in macrophages. J Virol, 71, 7488-7497.
  • Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, North R, Gerard C, Rollins BJ (1998): Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1- deficient mice. J Exp Med, 187, 601-608.
  • Luster AD (1998): Chemokines--chemotactic cytokines that mediate inflammation. N Engl J Med, 338, 436-445.
  • Mackay CR (2001): Chemokines: immunology's high impact factors. Nat Immunol, 2, 95-101.
  • Mahad DJ, Ransohoff RM (2003): The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin Immunol, 15, 23– 32.
  • Mc Cullough, KC, Crowther, JR (1986): The protective immune response against foot and mouth disease virus, re- lationship to virion topography. FMD Bulletin, 23, 2-6.
  • Rao CR (1973): Linear statistical inference and its appli- cations. John&Sons, New York.
  • Reckless J, Rubin EM, Verstuyft JB, Metcalfe JC, Grainger DJ (1999): Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesions. Circulation, 99, 2310-2306.
  • Sallusto F, Lanzavecchia A, Mackay CR (1998): Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today, 19, 568-574.
  • Sorbino F, Saiz M, Jimenez-Clavero MA, Nunez JI, Rosas MF, Baranowski E, Ley V (2001): Foot and Mouth Disease Virus: a long known virus, but a current threat. Vet Res, 32, 1-30.
  • Thanawongnuwech R, Young TF, Thacker BJ, Thacker EL (2001): Differential production of proinflammatory cytokines: in vitro PRRSV and Mycoplasma hyopneumoniae co-infection model. Vet Immunol Immunopathol, 79, 115-127.
  • Usherwood EJ, Nash AA (1995): Lymphocyte recognition of picornaviruses. J Gen Virol, 76, 499-508.
  • Van Reeth, Labarque G, Nauwynck H, Pensaert M (1999): Differential production of proinflammatory cytokines in the pig lung during different respiratory virus infections: correlations with pathogenicity. Res Vet Sci, 67, 47-52.
  • Van Reeth K, Van Gucht S, Pensaert M (2002): In vivo studies on cytokine involvement during acute viral respiratory disease of swine: troublesome bu rewarding. Vet Immunol Immunopathol, 87, 161-168.
  • Wong CK, Lam CW, Wu AK, Ip WK, Lee NL, Chan IH, Lit LC, Hui DS, Chan MH, Chung SS, Sung JJ (2004): Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol, 136, 95-103.
  • Yadav S, Sharma R, Chhabra R (2005): Interleukin-2 potentiates foot-and-mouth disease vaccinal immune responses in mice. Vaccine, 23, 3005-3009.
  • Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu J, Leonard EJ (1989): Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med, 169, 1449-1459.
  • Zoja C, Wang JM, Bettoni S, Sironi M, Renzi D, Chiaffarino F, Abboud HE, Van Damme J, Mantovani A, Remuzzi G (1991): Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony- stimulating factors, and interleukin-6 in human mesengial cells. Am J Pathol, 138, 991-1003.

Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi

Year 2006, , 91 - 95, 01.06.2006

Fatma Gül Yarım Cevat Nisbet Naci Öcal Gülay Çiftçi Aydın Coşkuner

https://doi.org/10.1501/Vetfak_0000000079

Abstract

Bu çalışmada, şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 (MCP-1) ve interlökin 1-α (IL-1α) düzeylerinin ve bu düzeyler ile kandaki lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi amaçlandı. Bu amaçla, 1-1.5
yaşlarında 16 adet şap hastalıklı ve 11 adet sağlıklı dana kullanıldı. Şap hastalıklı danalarda plazma MCP-1 ve IL-1α düzeyleri sağlıklı gruba göre önemli derecede yükselmiş bulundu (p<0.001). Şap hastalıklı danalarda plazma MCP-1 ve IL-1α düzeyleri ile kandaki lenfosit ve monosit sayıları arasında önemli derecede ilişki olduğu belirlendi (p<0.01). Kandaki lenfosit ve monosit artışına
paralel olarak plazma MCP-1 ve IL1-α düzeylerinin de önemli derecede artmış olması, MCP-1 ve IL-1α’nın şap hastalığının
patogenezinde rol aldığını düşündürmektedir

Keywords

Dana IL-1α lenfosit MCP-1 monosit şap hastalığı

References

  • Aderka D, Holtmann H, Toker L, Hahn T, Wallach D (1986): Tumor necrosis factor induction by Sendai virus. J Immunol, 136, 2938-2342.
  • Apte RN, Voronov E (2002): Interleukin-1--a major pleiotropic cytokine in tumor-host interactions. Semin Cancer Biol, 12, 277-290.
  • Baggiolini M, Dewald B, Moser B (1997): Human chemokines: an update. Annu Rev Immunol, 15, 675-705.
  • Boring L, Gosling J, Cleary M, Charo IF (1998): Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature, 394, 894– 897.
  • Breen EC, Rezai K, Nakajima K, Beall GN, Mitsuyasu RT, Hirano T, Kishimoto T, Martinez-Maza O (1990): Infection with HIV is associated with elevated IL-6 levels and production. J Immunol, 144, 480-484.
  • Bubfeld D, Kaufmann A, Meyer RG, Gemsa D, Sprenger H (1998): Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated ınfluenza A virus. Cell Immun, 186, 1-7.
  • Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM (1990): Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci USA, 87, 5134-5138.
  • Davies C (1994): Principles. In The Immunoassay Handbook. D. Wild, ed. Stockton Press, New York, p. 3- 47.
  • Dinarello CA (1996): Biologic basis for interleukin-1 in disease. Blood, 87, 2095-2147.
  • Dinter Z, Morein B (1990): Virus Infections of Ruminants, Elsevier Science Publishers B.V. p. 506-508.
  • Dunphy J, Horvath A, Barcham G, Balic A, Bischof R, Meeusen E (2001): Isolation, characterisation and expression of mRNAs encoding the ovine CC chemokines, monocyte chemoattractant protein (MCP)-1alpha and -2. Vet Immunol Immunopathol, 82, 153-164.
  • Eckersall PD (2000): Recent advances and future pros- pects for the use of acute phase proteins as markers of dis- ease in animals. Revue Med Vet, 151, 577-584.
  • England JM, Rowan RM, van Assendelft OW, Coulter WH, Groner W, Jones AR, Koepke JA, Lewis SM, Shinton NK, Thom R (1984): Protocol for evaluation of automated blood cell counters. International Committee for Standardization in Haematology (ICSH). Clin Lab Haematol, 6, 269-84.
  • Gangur V, Birmingham NP, Thanesvorakul S (2002): Chemokines in health and disease. Vet Immunol Immunopathol, 86, 127-136.
  • Gu L, Tseng S, Rollins BJ (1999): Monocyte chemoattractant protein-1. Chem Immunol, 72, 7– 29.
  • Horadagoda NU, Knox KM, Gibbs HA, Reid SW, Horadagoda A, Edwards SE, Eckersall PD (1999): Acute phase proteins in cattle: discrimination between acute and chronic inflammation. Vet Rec, 17, 144, 437- 441.
  • Imhof BA, Dunon D (1995): Leukocyte migration and adhesion. Adv Immunol, 58, 345-416.
  • Janeway CA, Medzhitov R (2002): Innate immune rec- ognition. Annu Rev Immunol, 20, 197-216.
  • Kuby J (1997): Immunology, 3rd Ed., WH Freeman and Co, New York.
  • Lechner F, Machado J, Bertoni G, Seow HF, Dobbelaere DA, Peterhans E (1997): Caprine arthritis encephalitis virus dysregulates the expression of cytokines in macrophages. J Virol, 71, 7488-7497.
  • Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, North R, Gerard C, Rollins BJ (1998): Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1- deficient mice. J Exp Med, 187, 601-608.
  • Luster AD (1998): Chemokines--chemotactic cytokines that mediate inflammation. N Engl J Med, 338, 436-445.
  • Mackay CR (2001): Chemokines: immunology's high impact factors. Nat Immunol, 2, 95-101.
  • Mahad DJ, Ransohoff RM (2003): The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin Immunol, 15, 23– 32.
  • Mc Cullough, KC, Crowther, JR (1986): The protective immune response against foot and mouth disease virus, re- lationship to virion topography. FMD Bulletin, 23, 2-6.
  • Rao CR (1973): Linear statistical inference and its appli- cations. John&Sons, New York.
  • Reckless J, Rubin EM, Verstuyft JB, Metcalfe JC, Grainger DJ (1999): Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesions. Circulation, 99, 2310-2306.
  • Sallusto F, Lanzavecchia A, Mackay CR (1998): Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today, 19, 568-574.
  • Sorbino F, Saiz M, Jimenez-Clavero MA, Nunez JI, Rosas MF, Baranowski E, Ley V (2001): Foot and Mouth Disease Virus: a long known virus, but a current threat. Vet Res, 32, 1-30.
  • Thanawongnuwech R, Young TF, Thacker BJ, Thacker EL (2001): Differential production of proinflammatory cytokines: in vitro PRRSV and Mycoplasma hyopneumoniae co-infection model. Vet Immunol Immunopathol, 79, 115-127.
  • Usherwood EJ, Nash AA (1995): Lymphocyte recognition of picornaviruses. J Gen Virol, 76, 499-508.
  • Van Reeth, Labarque G, Nauwynck H, Pensaert M (1999): Differential production of proinflammatory cytokines in the pig lung during different respiratory virus infections: correlations with pathogenicity. Res Vet Sci, 67, 47-52.
  • Van Reeth K, Van Gucht S, Pensaert M (2002): In vivo studies on cytokine involvement during acute viral respiratory disease of swine: troublesome bu rewarding. Vet Immunol Immunopathol, 87, 161-168.
  • Wong CK, Lam CW, Wu AK, Ip WK, Lee NL, Chan IH, Lit LC, Hui DS, Chan MH, Chung SS, Sung JJ (2004): Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol, 136, 95-103.
  • Yadav S, Sharma R, Chhabra R (2005): Interleukin-2 potentiates foot-and-mouth disease vaccinal immune responses in mice. Vaccine, 23, 3005-3009.
  • Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu J, Leonard EJ (1989): Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med, 169, 1449-1459.
  • Zoja C, Wang JM, Bettoni S, Sironi M, Renzi D, Chiaffarino F, Abboud HE, Van Damme J, Mantovani A, Remuzzi G (1991): Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony- stimulating factors, and interleukin-6 in human mesengial cells. Am J Pathol, 138, 991-1003.
There are 37 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Surgery
Journal Section Research Article
Authors

Fatma Gül Yarım

Cevat Nisbet

Naci Öcal

Gülay Çiftçi

Aydın Coşkuner

Publication Date June 1, 2006
Published in Issue Year 2006

Cite

APA Yarım, F. G., Nisbet, C., Öcal, N., Çiftçi, G., et al. (2006). Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 53(2), 91-95. https://doi.org/10.1501/Vetfak_0000000079
AMA Yarım FG, Nisbet C, Öcal N, Çiftçi G, Coşkuner A. Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Univ Vet Fak Derg. June 2006;53(2):91-95. doi:10.1501/Vetfak_0000000079
Chicago Yarım, Fatma Gül, Cevat Nisbet, Naci Öcal, Gülay Çiftçi, and Aydın Coşkuner. “Şap hastalıklı Danalarda Plazma Monosit Kemoatraktan Protein-1 Ve İnterlökin-1α düzeylerinin Ve Bu düzeylerle Kan Lenfosit Ve Monosit sayıları arasındaki ilişkilerin Incelenmesi”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 53, no. 2 (June 2006): 91-95. https://doi.org/10.1501/Vetfak_0000000079.
EndNote Yarım FG, Nisbet C, Öcal N, Çiftçi G, Coşkuner A (June 1, 2006) Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Üniversitesi Veteriner Fakültesi Dergisi 53 2 91–95.
IEEE F. G. Yarım, C. Nisbet, N. Öcal, G. Çiftçi, and A. Coşkuner, “Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi”, Ankara Univ Vet Fak Derg, vol. 53, no. 2, pp. 91–95, 2006, doi: 10.1501/Vetfak_0000000079.
ISNAD Yarım, Fatma Gül et al. “Şap hastalıklı Danalarda Plazma Monosit Kemoatraktan Protein-1 Ve İnterlökin-1α düzeylerinin Ve Bu düzeylerle Kan Lenfosit Ve Monosit sayıları arasındaki ilişkilerin Incelenmesi”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 53/2 (June 2006), 91-95. https://doi.org/10.1501/Vetfak_0000000079.
JAMA Yarım FG, Nisbet C, Öcal N, Çiftçi G, Coşkuner A. Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Univ Vet Fak Derg. 2006;53:91–95.
MLA Yarım, Fatma Gül et al. “Şap hastalıklı Danalarda Plazma Monosit Kemoatraktan Protein-1 Ve İnterlökin-1α düzeylerinin Ve Bu düzeylerle Kan Lenfosit Ve Monosit sayıları arasındaki ilişkilerin Incelenmesi”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, vol. 53, no. 2, 2006, pp. 91-95, doi:10.1501/Vetfak_0000000079.
Vancouver Yarım FG, Nisbet C, Öcal N, Çiftçi G, Coşkuner A. Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Univ Vet Fak Derg. 2006;53(2):91-5.