Research Article
Year 2021,
, 155 - 160, 31.03.2021
Abstract
Supporting Institution
TÜBİTAK
Project Number
TOVAG-107O177
References
- Ambrose JD, Kastelic JP, Rajamahendran R, et al (2005): Progesterone (CIDR)-based timed AI protocols using GnRH, porcine LH or estradiol cypionate for dairy heifers: ovarian and endocrine responses and pregnancy rates. Theriogenology, 64, 1457-1474.
- Bartolome JA, Sozzi A, McHale J, et al (2005): Resynchronization of ovulation and timed insemination in lactating dairy cows, I: use of the Ovsynch and Heatsynch protocols after non-pregnancy diagnosis by ultrasonography. Theriogenology, 63, 1617-1627.
- Bartolome JA, Sozzi A, McHale J, et al (2005): Resynchronization of ovulation and timed insemination in lactating dairy cows, II: assigning protocols according to stages of the estrous cycle, or presence of ovarian cysts or anestrus. Theriogenology, 63, 1628-1642.
- Bisinotto RS, Castro LO, Pansani MB et al (2015): Progesterone supplementation to lactating dairy cows without a corpus luteum at initiation of the Ovsynch protocol. J Dairy Sci, 98, 2515-2528.
- Cavalieri J (2018): Absence of a corpus luteum and relatively lesser concentrations of progesterone during the period of pre-ovulatory follicle emergence results in lesser pregnancy rates in Bos indicus cattle. Anim Reprod Sci, 204, 39-49.
- Cavalieri J, Hepworth G, Fitzpatrick LA, et al (2006): Manipulation and control of the estrous cycle in pasture-based dairy cows. Theriogenology, 65, 45-64.
- Chebel RC, Santos JEP, Cerri RLA, et al (2006): Reproduction in dairy cows following progesterone insert presynchronization and resynchronization protocols. J Dairy Sci, 89, 4205-4219.
- Çolak A, Bekyürek T, Öztürkler Y (1995): İneklerde postpartum dönemde PGF2α ile östrus sinkronizasyonu çalışmaları. Kafkas Üniv Vet Fak Derg, 1, 22-24.
- Colazo MG, Kastelic JP, Mainar-Jaime RC et al (2006): Resynchronization of previously timed-inseminated beef heifers with progestins. Theriogenology, 65, 557-572.
- Colazo MG, Kastelic JP, Small JA et al (2007): Resynchronization of estrus in beef cattle: ovarian function, estrus and fertility following progestin treatment and treatments to synchronize ovarian follicular development and estrus. Can Vet J, 48, 49-56.
- Colazo MG, Kastelic JP, Whittaker PR et al (2004): Fertility in beef cattle given a new or previously used CIDR insert and estradiol, with or without progesterone. Anim Reprod Sci, 81, 25-34.
- Edmonson AJ, Lean IJ, Weaver LD et al (1989): A body condition scoring chart for Holstein dairy cows. J Dairy Sci, 72, 68-78.
- Fricke PM, Caraviello DZ, Weigel KA et al (2003): Fertility of dairy cows after resynchronization of ovulation at three intervals following first timed insemination. J Dairy Sci, 86, 3941-3950.
- Galvano KN, Santos JEP, Cerri RL et al (2007): Evaluation of methods of resynchronization for insemination in cows of unknown pregnancy status. J Anim Sci, 90, 4240-4252.
- Jones AL, Lamb GC (2008): Nutrition, synchronization, and management of beef embryo transfer recipients. Theriogenology, 69, 107-115.
- Leroy JLMR, de Kruif A (2006): Reduced reproductive performance in high producing dairy cows: Is there actually a problem?. Vlaams Diergen Tijds, 75, 55-60.
- Lopez HI, Whittaker P, Behrouzi A et al (2018): Effect of initial GnRH and time of insemination on reproductive performance in cyclic and acyclic beef heifers subjected to a 5-d Cosynch plus progesterone protocol. Theriogenology, 106, 36-45.
- Lucy MC, Billings HJ, Butler WR et al (2001): Efficacy of an intravaginal progesterone insert and an injection of PGF2alpha for synchronizing estrus and shortening the interval to pregnancy in postpartum beef cows, peripubertal beef heifers, and dairy heifers. J Anim Sci, 79, 982-995.
- Martinez MF, Kastelic JP, Adams GP et al (2000): Estrus synchronization and pregnancy rates in beef cattle given CIDR-B, prostaglandin and estradiol, or GnRH. Can Vet J, 41, 786-790.
- Martinez MF, Kastelic JP, Adams GP et al (2002): The use of a progesterone-releasing device (CIDR-B) or melengestrol acetate with GnRH, LH, or estradiol benzoate for fixed-time AI in beef heifers. J Anim Sci, 80, 1746-1751.
- Moreira F, de la Sota RL, Diaz T et al (2000): Effects of day of the estrous cycle at the initiation of a timed artificial insemination protocol on reproductive responses in dairy heifers. J Anim Sci, 78, 1568-1576.
- Penny CD, Lowman BG, Scott NA et al (2000): Repeated oestrus synchronization of beef cows with progesterone implants and the effects of a gonadotrophin-releasing hormone against at implant insertion. Vet Rec, 146, 395-398.
- Prakash BS, Meyer HHD, Schallenberger E et al (1987): Development of sensitive Enzymeimmunoassay (EIA) for progesterone determination in unextracted bovine plasma using the second antibody technique. J Steroid Biochem, 28, 623-627.
- Purcell SH, Beal WE, Gray KR (2005): Effect of a CIDR insert and flunixin meglumine, administered at the time of embryo transfer, on pregnancy rate and resynchronization of estrus in beef cattle. Theriogenology, 64, 867-878.
- Rivera H, Lopez H, Fricke PM (2005): Use of intravaginal progesterone-releasing inserts in a synchronization protocol before timed AI and for synchronizing return to estrus in Holstein heifers. J Dairy Sci, 88, 957-968.
- Silva E, Sterry RA, Kolb D et al (2007): Effect of interval to resynchronization of ovulation on fertility of lactating Holstein cows when using transrectal ultrasonography or a pregnancy-associated glycoprotein enzyme-linked immunosorbent assay to diagnose pregnancy status. J Dairy Sci, 92, 3643-3650.
- Sterry RA, Welle ML, Fricke PM (2006): Effect of interval from timed artificial insemination to initiation of resynchronization of ovulation on fertility of lactating dairy cows. J Dairy Sci, 89, 2099-2109.
- Stevenson JS, Kobayashi Y, Thompson KE (1999): Reproductive performance of dairy cows in various programmed breeding systems including ovsynch and combinations of gonadotropin-releasing hormone and prostaglandin F2α. J Dairy Sci, 82, 506-515.
- Stevenson JS, Pursley JR, Garverick HA et al (2006): Treatment of cycling and noncycling lactating dairy cows with progesterone during ovsynch. J Dairy Sci, 89, 2567-2578.
- Thatcher WW, Bilby TR, Bartolome JA, Silvestre F et al (2006): Strategies for improving fertility in the modern dairy cow. Theriogenology, 65, 30-44.
- Van Eerdenburg FJCM (2006): Estrus detection in dairy cattle: How to beat the bull. Vlaams Diergen Tijds, 75, 61-69.
- Wiltbank MC, Sartori R, Herlihy MM et al (2011): Managing the dominant follicle in lactating dairy cows. Theriogenology, 76, 1568–1582.
- Zuluaga JF, Williams GL (2007): High-pressure steam sterilization of previously used CIDR inserts enhances the magnitude of the acute increase in circulating progesterone after insertion in cows. Anim Reprod Sci, 107, 30-35.
The effectiveness of intravaginal progesterone insert in Ovsynch and resynchronization protocols in cyclic and non-cyclic Holstein heifers
Abstract
In the present study, it was aimed to compare of resynchronization with used progesterone (P4) releasing intravaginal device (PRID), with modified ovulation synchronization in cyclic and non-cyclic Holstein heifers. Animals were randomly divided into two groups; Group I (GI, n=87) and Group II (GII, n=88). Fixed-time artificial insemination (FTAI) following modified Ovsynch protocol with PRID insertion, was performed to all animals. In GI, used PRID was reinserted to the same animals, 15 days after the first FTAI (day 25) for 12 days. Pregnancies were detected by ultrasound in all groups on day 37. For resynchronization, prostaglandin (PG) F2α was applied to non-pregnant animals on day 37. In GI, following 48 hours from PGF2α injection, the gonadotropin-releasing hormone was administrated, and after 18 hours the second FTAI was performed. No additional treatments were applied to the non-pregnant animals found in GII, and heifers were taken to the routine service program. In both groups, the second pregnancy diagnosis was performed 27 days after inseminations by transrectal ultrasonography. Pregnancy rates (PR) following the first and overall inseminations in cyclic and non-cyclic heifers (GI and GII) were detected as 66.4% and 52.3% (P>0.05); 76.3% and 59.1% (P>0.05), respectively. In conclusion, the usage of PRID in the Ovsynch and resynchronization protocol resulted in higher PRs of non-cyclic heifers than cyclic heifers. Moreover, this study reveals that the initial P4 levels of non-cyclic animals should be used as a determinant for pregnancy success in dairy heifers.
Keywords
Project Number
TOVAG-107O177
References
- Ambrose JD, Kastelic JP, Rajamahendran R, et al (2005): Progesterone (CIDR)-based timed AI protocols using GnRH, porcine LH or estradiol cypionate for dairy heifers: ovarian and endocrine responses and pregnancy rates. Theriogenology, 64, 1457-1474.
- Bartolome JA, Sozzi A, McHale J, et al (2005): Resynchronization of ovulation and timed insemination in lactating dairy cows, I: use of the Ovsynch and Heatsynch protocols after non-pregnancy diagnosis by ultrasonography. Theriogenology, 63, 1617-1627.
- Bartolome JA, Sozzi A, McHale J, et al (2005): Resynchronization of ovulation and timed insemination in lactating dairy cows, II: assigning protocols according to stages of the estrous cycle, or presence of ovarian cysts or anestrus. Theriogenology, 63, 1628-1642.
- Bisinotto RS, Castro LO, Pansani MB et al (2015): Progesterone supplementation to lactating dairy cows without a corpus luteum at initiation of the Ovsynch protocol. J Dairy Sci, 98, 2515-2528.
- Cavalieri J (2018): Absence of a corpus luteum and relatively lesser concentrations of progesterone during the period of pre-ovulatory follicle emergence results in lesser pregnancy rates in Bos indicus cattle. Anim Reprod Sci, 204, 39-49.
- Cavalieri J, Hepworth G, Fitzpatrick LA, et al (2006): Manipulation and control of the estrous cycle in pasture-based dairy cows. Theriogenology, 65, 45-64.
- Chebel RC, Santos JEP, Cerri RLA, et al (2006): Reproduction in dairy cows following progesterone insert presynchronization and resynchronization protocols. J Dairy Sci, 89, 4205-4219.
- Çolak A, Bekyürek T, Öztürkler Y (1995): İneklerde postpartum dönemde PGF2α ile östrus sinkronizasyonu çalışmaları. Kafkas Üniv Vet Fak Derg, 1, 22-24.
- Colazo MG, Kastelic JP, Mainar-Jaime RC et al (2006): Resynchronization of previously timed-inseminated beef heifers with progestins. Theriogenology, 65, 557-572.
- Colazo MG, Kastelic JP, Small JA et al (2007): Resynchronization of estrus in beef cattle: ovarian function, estrus and fertility following progestin treatment and treatments to synchronize ovarian follicular development and estrus. Can Vet J, 48, 49-56.
- Colazo MG, Kastelic JP, Whittaker PR et al (2004): Fertility in beef cattle given a new or previously used CIDR insert and estradiol, with or without progesterone. Anim Reprod Sci, 81, 25-34.
- Edmonson AJ, Lean IJ, Weaver LD et al (1989): A body condition scoring chart for Holstein dairy cows. J Dairy Sci, 72, 68-78.
- Fricke PM, Caraviello DZ, Weigel KA et al (2003): Fertility of dairy cows after resynchronization of ovulation at three intervals following first timed insemination. J Dairy Sci, 86, 3941-3950.
- Galvano KN, Santos JEP, Cerri RL et al (2007): Evaluation of methods of resynchronization for insemination in cows of unknown pregnancy status. J Anim Sci, 90, 4240-4252.
- Jones AL, Lamb GC (2008): Nutrition, synchronization, and management of beef embryo transfer recipients. Theriogenology, 69, 107-115.
- Leroy JLMR, de Kruif A (2006): Reduced reproductive performance in high producing dairy cows: Is there actually a problem?. Vlaams Diergen Tijds, 75, 55-60.
- Lopez HI, Whittaker P, Behrouzi A et al (2018): Effect of initial GnRH and time of insemination on reproductive performance in cyclic and acyclic beef heifers subjected to a 5-d Cosynch plus progesterone protocol. Theriogenology, 106, 36-45.
- Lucy MC, Billings HJ, Butler WR et al (2001): Efficacy of an intravaginal progesterone insert and an injection of PGF2alpha for synchronizing estrus and shortening the interval to pregnancy in postpartum beef cows, peripubertal beef heifers, and dairy heifers. J Anim Sci, 79, 982-995.
- Martinez MF, Kastelic JP, Adams GP et al (2000): Estrus synchronization and pregnancy rates in beef cattle given CIDR-B, prostaglandin and estradiol, or GnRH. Can Vet J, 41, 786-790.
- Martinez MF, Kastelic JP, Adams GP et al (2002): The use of a progesterone-releasing device (CIDR-B) or melengestrol acetate with GnRH, LH, or estradiol benzoate for fixed-time AI in beef heifers. J Anim Sci, 80, 1746-1751.
- Moreira F, de la Sota RL, Diaz T et al (2000): Effects of day of the estrous cycle at the initiation of a timed artificial insemination protocol on reproductive responses in dairy heifers. J Anim Sci, 78, 1568-1576.
- Penny CD, Lowman BG, Scott NA et al (2000): Repeated oestrus synchronization of beef cows with progesterone implants and the effects of a gonadotrophin-releasing hormone against at implant insertion. Vet Rec, 146, 395-398.
- Prakash BS, Meyer HHD, Schallenberger E et al (1987): Development of sensitive Enzymeimmunoassay (EIA) for progesterone determination in unextracted bovine plasma using the second antibody technique. J Steroid Biochem, 28, 623-627.
- Purcell SH, Beal WE, Gray KR (2005): Effect of a CIDR insert and flunixin meglumine, administered at the time of embryo transfer, on pregnancy rate and resynchronization of estrus in beef cattle. Theriogenology, 64, 867-878.
- Rivera H, Lopez H, Fricke PM (2005): Use of intravaginal progesterone-releasing inserts in a synchronization protocol before timed AI and for synchronizing return to estrus in Holstein heifers. J Dairy Sci, 88, 957-968.
- Silva E, Sterry RA, Kolb D et al (2007): Effect of interval to resynchronization of ovulation on fertility of lactating Holstein cows when using transrectal ultrasonography or a pregnancy-associated glycoprotein enzyme-linked immunosorbent assay to diagnose pregnancy status. J Dairy Sci, 92, 3643-3650.
- Sterry RA, Welle ML, Fricke PM (2006): Effect of interval from timed artificial insemination to initiation of resynchronization of ovulation on fertility of lactating dairy cows. J Dairy Sci, 89, 2099-2109.
- Stevenson JS, Kobayashi Y, Thompson KE (1999): Reproductive performance of dairy cows in various programmed breeding systems including ovsynch and combinations of gonadotropin-releasing hormone and prostaglandin F2α. J Dairy Sci, 82, 506-515.
- Stevenson JS, Pursley JR, Garverick HA et al (2006): Treatment of cycling and noncycling lactating dairy cows with progesterone during ovsynch. J Dairy Sci, 89, 2567-2578.
- Thatcher WW, Bilby TR, Bartolome JA, Silvestre F et al (2006): Strategies for improving fertility in the modern dairy cow. Theriogenology, 65, 30-44.
- Van Eerdenburg FJCM (2006): Estrus detection in dairy cattle: How to beat the bull. Vlaams Diergen Tijds, 75, 61-69.
- Wiltbank MC, Sartori R, Herlihy MM et al (2011): Managing the dominant follicle in lactating dairy cows. Theriogenology, 76, 1568–1582.
- Zuluaga JF, Williams GL (2007): High-pressure steam sterilization of previously used CIDR inserts enhances the magnitude of the acute increase in circulating progesterone after insertion in cows. Anim Reprod Sci, 107, 30-35.
There are 33 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Article |
| Authors | |
| Project Number | TOVAG-107O177 |
| Publication Date | March 31, 2021 |
| Published in Issue | Year 2021 |