Among the skin tumors, intracutaneous cornifYing
epithelioma and well-differentiated squamous cell carcinoma are .s'imilar. The
purpose of this study was to compare the immunostainingfor proliferating cell
nuclear antigen (PCNA) clone PC i O, interphase nucleolar organizer regions
staining (AgNORs) methods and mitotic index in these tumorso JıIve
intracutaneous cornifYing epitheliomas in the dogs and 20 well-differentiated
squamous cell carcinomas in various species were chosen. All sample.~ were
.fixed in formalin and embedded in parapin. The mean number ofAgNOR was
determined in 50 basal and 50 suprabasal cells of each tumor under an oil
immersion lens at a magnification of 10()O.PCNA-Iabeledfractions and mitotic
index were estimated in the same areas of these tumors in JO high power
fields. AgNOR count (p < O,OJ) was significant, but peNA index and mitotic
index were not significant in Mann-Whitney U test to compare intracutaneous
cornifYing epithelioma and well-differentiated squamous cell carcinoma.
Primary Language | English |
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Subjects | Veterinary Surgery |
Journal Section | Research Article |
Authors | |
Publication Date | January 1, 1996 |
Published in Issue | Year 1996 |