Research Article
Effects of dietary melatonin on broiler chicken exposed to continuous lighting during the first two weeks of life
Abstract
Intensive broiler chicken production involves different lighting regimes, which affects a natural cycle of secretion of melatonin, a hormone included in multiple physiological processes in a bird's body. This research aimed to determine the effects of dietary melatonin supplementation during the first two weeks of broiler chickens' life, bred under constant 24 h lighting, on their health and some hematological, biochemical, and production parameters. The study lasted 6 weeks. Three hundred and twenty 1-day chickens were divided into two groups (control - C and experimental - M), with four replications and 40 chickens in each replica. In the first two weeks (the first phase of the study), a continuous lighting mode 24L: 0D was applied. Group M was receiving a diet supplemented with 30 mg/kg synthetic melatonin only during the first phase. Group C had a diet without melatonin supplementation throughout the whole study. Melatonin addition had a statistically significant effect (P<0.01) on the mean values of body weight and daily weight gain at the end of the 1st, 2nd, 3rd, 4th, 5th, and 6th week. The chickens of the experimental group have had a significantly higher value of the European Production Efficiency Factor (EPEF) (P<0.05). The results presented in this paper indicate a direct benefit in stress relief in broilers and a value of the organism's antioxidant system promotion, manifested by improved production performance and fattening efficiency.
Keywords
Supporting Institution
This research was funded by the Ministry of Education, Science and Technological Development, Republic of Serbia, contracts No 451-03-68/2020-14/200116 and 451-03-68/2020-14/200022.
Project Number
451-03-68/2020-14/200116 and 451-03-68/2020-14/200022
References
- Abbas A, Gehad A, Hendricks G, et al (2007): The effect of lighting program and melatonin on the alleviation of the negative impact of heat stress on the immune response in broiler chickens. Int J Poult Sci, 6, 651-660.
- Ahmed HH, Essawy GS, Salem HA, et al (2011): Effect of Melatonin on Some Hematological Parameters and Immune Status of Broiler Chicks. J Agric Sci, 3, 243-254.
- Akbarian A, Kazerani HR, Mohri M, et al (2014): Exogenous melatonin improves growth performance, intestinal microbiota and morphology in temporarily feed restricted broilers. Livest Sci, 167, 400-407.
- Amao SR, Oyewumi SO (2017): Influence of Age and Strain on Haematological and Blood Biochemical Indices in Broiler Chickens Reared in Derived Savanna Environment of Nigeria. Am J Life Sci, 5, 34-38.
- Apeldoorn EJ, Schrama JW, Mashaly MM, et al (1999): Effect of Melatonin and Lighting Schedule on Energy Metabolism in Broiler Chickens. Poult Sci, 78, 223–229.
- Arowolo M, He H, He S, et al (2019): The implication of lighting programmes in intensive broiler production system. Worlds Poult Sci J, 75, 17-28.
- Aviagen (2014): ROSS 308 Broiler Management Handbook. Available at Ross-308-Broiler-PO-2014-EN.pdf (winmixsoft.com) (Accessed 15 September 2020).
- Aviagen (2014): Ross 308 Broiler Nutrition Specifications. Available at http://en.aviagen.com/assets/Tech_Center /Ross_Broiler/Ross308BroilerNutritionSpecs2014-EN.pdf. (Accessed 15 September 2020).
- Berger J (2004): Regulation of circadian rhythms. J Appl Biomedicine, 2, 131-140.
- Beutler E (1984): Red cell metabolism, In: Beutler, E. (Ed.), A Manual of Biochemical Methods. 3rd ed. Grune and Stratton, New York.
- Božić T, Gvozdić D (1995): Pathological physiology of domestic animals (selected chapters and practicum). The University of Belgrade, Veterinary Faculty, Belgrade.
- Brennan CP, Hendricks GL III, El-Sheikh TM, et al (2002): Melatonin and the Enhancement of Immune Responses in Immature Male Chickens. Poult Sci, 81, 371-375.
- Bubenik GA (2002): Gastrointestinal melatonin: Localization, Function, and Clinical Relevance. Dig Dis Sci, 42, 2336-2348.
- Çalışlar S, Yeter B, Şahin A (2018): Importance of Melatonin on Poultry. KSÜ Tar Doğa Derg, 21, 987-997.
- Calvo JR, Gonzalez-Yanes C, Maldonado MD (2013): The role of melatonin in the cells of the innate immunity: a review. J Pineal Res, 55, 103–120.
- Carrillo-Vico A, Lardone PJ, Álvarez-Sánchez N, et al (2013): Melatonin: Buffering the Immune System. Int J Mol Sci, 14, 8638-8683.
- Cassone VM, Paulose JK, Whitfield-Rucker MG, et al (2009): Time’s arrow flies like a bird: two paradoxes for avian circadian biology. Gen Comp Endocrinol, 163, 109–116.
- Csernus V, Mess B (2003): Biorhythms and pineal gland. Neuro Endocrinol Lett, 24, 404-411.
- Egbuniwe C, Ayo J (2016): Physiological roles of avian eyes in light perception and their response to photoperiodicity. Worlds Poult Sci J, 72, 605-614.
- Farag H, Ali Hassan R, Al Lehyani SH (2020): Protective effect of melatonin on hemoglobin damage induced by gamma irradiation. JETIR, 7, 320-325. Available at: http://www.jetir.org/papers/JETIR1912042.pdf (Accessed 13 September 2020).
- Gross WB, Siegel HS (1983): Evaluation of the heterophil/lymphocyte ratio as a measure of stress in chickens. Avian Dis, 27, 972-979.
- Moore CB, Siopes TD (2000): Effects of light conditions and melatonin supplementation on the cellular and humoral immune responses in Japanese quail Coturnix coturnix japonica. Gen Comp Endocrinol, 119, 95–104.
- Mund MD, Riaz M, Mirza MA, et al (2019): Effect of dietary tryptophan supplementation on growth performance, immune response and anti‐oxidant status of broiler chickens from 7 to 21 days. Vet Med Sci, 6, 48-53.
- Olanrewaju H, Thaxton J, Dozier W, et al (2006): A review of lighting programs for broiler production. Int J Poul Sci, 5, 301-308.
- Pattison M (2008): Poultry Diseases. Elsevier Health Sciences, Amsterdam.
- Reiter R, Tan D, Galano A (2014): Melatonin: Exceeding expectations. Physiol, 29, 325-333.
- RSPCA (2017): RSPCA welfare standards for meat chickens. Available at: https://science.rspca.org.uk/ sciencegroup/farmanimals/standards/chickens (Accessed 12 June 2020).
- Rusov Č (2002): Hematology of birds. Scientific Veterinary Institute of Serbia (NIVS). Belgrade.
- Scanes C, Lauterio T (1984): Growth hormone: Its physiology and control. J Exp Zool, 232, 443-452.
- Singh R., Cook N., Cheng K. M., et al (2009): Invasive and noninvasive measurement of stress in laying hens kept in conventional cages and in floor pens. Poult Sci, 88, 1346–1351.
- Sinkalu V (2012): Effect of melatonin on physiological responses of broiler chickens to continuous lighting, heat and road transportation stress during the hot-dry season. Doctoral Dissertation. Department of Physiology, Faculty of Veterinary medicine, Ahmadu Bello University, Zaria, Nigeria.
- Sun YY, Li YL, Li DL, et al (2017): Responses of broilers to the near-continuous lighting, constant 16-h lighting, and constant 16-h lighting with a 2-h night interruption. Livest Sci, 206, 135-140.
- Škrbić Z, Pavlovski Z, Lukić M, et al (2013): The role of light in broiler production. 222-231. In: Proceedings 10th International Symposium “Modern Trends in Livestock Production”, Belgrade.
- Talebi A, Asri-Rezaei S, Rozeh-Chai R, et al (2005): Comparative Studies on Haematological Values of Broiler Strains (Ross, Cobb, Arbor-acres and Arian). Int J Poult Sci, 4, 573-579.
- Tehrani A, Javanbakht J, Askari S, et al (2012): Haematological Studies on Broiler Chickens Fed with Different Levels of Artemia Urmiana. J Biotechnol Biomater, 2, 138.
- Weiss DJ, Wardrop JK (2011): Schalm's Veterinary Hematology. Sixth Edition. Wiley-Blackwell. Washington.
- Zavodnik IB, Domanski AV, Lapshina EA, et al (2006): Melatonin directly scavenges free radicals generated in red blood cells and a cell-free system: Chemiluminescence measurements and theoretical calculations. Life Sci, 79, 391-400.
- Zeman M, Buyse J, Lamošova D, et al (1999): Role of melatonin in the control of growth and growth hormone secretion in poultry. Appl Anim Behav Sci, 17, 199-207.
- Zeman M, Herichova I (2011): Circadian melatonin production develops faster in birds than in mammals. Gen Comp Endocrinol, 172, 23-30.
- Zhao D, Yu Y, Shen Y, et al (2019): Melatonin synthesis and function: Evolutionary history in animals and plants. Front Endocrinol, 10, 249.
- Zheng L, Ma Y, Gu L, et al (2013): Growth performance, antioxidant status, and nonspecific immunity in broilers under different lighting regimes. J Appl Poult Res, 22, 798-807.
Year 2022,
, 361 - 366, 30.09.2022
Abstract
Project Number
451-03-68/2020-14/200116 and 451-03-68/2020-14/200022
References
- Abbas A, Gehad A, Hendricks G, et al (2007): The effect of lighting program and melatonin on the alleviation of the negative impact of heat stress on the immune response in broiler chickens. Int J Poult Sci, 6, 651-660.
- Ahmed HH, Essawy GS, Salem HA, et al (2011): Effect of Melatonin on Some Hematological Parameters and Immune Status of Broiler Chicks. J Agric Sci, 3, 243-254.
- Akbarian A, Kazerani HR, Mohri M, et al (2014): Exogenous melatonin improves growth performance, intestinal microbiota and morphology in temporarily feed restricted broilers. Livest Sci, 167, 400-407.
- Amao SR, Oyewumi SO (2017): Influence of Age and Strain on Haematological and Blood Biochemical Indices in Broiler Chickens Reared in Derived Savanna Environment of Nigeria. Am J Life Sci, 5, 34-38.
- Apeldoorn EJ, Schrama JW, Mashaly MM, et al (1999): Effect of Melatonin and Lighting Schedule on Energy Metabolism in Broiler Chickens. Poult Sci, 78, 223–229.
- Arowolo M, He H, He S, et al (2019): The implication of lighting programmes in intensive broiler production system. Worlds Poult Sci J, 75, 17-28.
- Aviagen (2014): ROSS 308 Broiler Management Handbook. Available at Ross-308-Broiler-PO-2014-EN.pdf (winmixsoft.com) (Accessed 15 September 2020).
- Aviagen (2014): Ross 308 Broiler Nutrition Specifications. Available at http://en.aviagen.com/assets/Tech_Center /Ross_Broiler/Ross308BroilerNutritionSpecs2014-EN.pdf. (Accessed 15 September 2020).
- Berger J (2004): Regulation of circadian rhythms. J Appl Biomedicine, 2, 131-140.
- Beutler E (1984): Red cell metabolism, In: Beutler, E. (Ed.), A Manual of Biochemical Methods. 3rd ed. Grune and Stratton, New York.
- Božić T, Gvozdić D (1995): Pathological physiology of domestic animals (selected chapters and practicum). The University of Belgrade, Veterinary Faculty, Belgrade.
- Brennan CP, Hendricks GL III, El-Sheikh TM, et al (2002): Melatonin and the Enhancement of Immune Responses in Immature Male Chickens. Poult Sci, 81, 371-375.
- Bubenik GA (2002): Gastrointestinal melatonin: Localization, Function, and Clinical Relevance. Dig Dis Sci, 42, 2336-2348.
- Çalışlar S, Yeter B, Şahin A (2018): Importance of Melatonin on Poultry. KSÜ Tar Doğa Derg, 21, 987-997.
- Calvo JR, Gonzalez-Yanes C, Maldonado MD (2013): The role of melatonin in the cells of the innate immunity: a review. J Pineal Res, 55, 103–120.
- Carrillo-Vico A, Lardone PJ, Álvarez-Sánchez N, et al (2013): Melatonin: Buffering the Immune System. Int J Mol Sci, 14, 8638-8683.
- Cassone VM, Paulose JK, Whitfield-Rucker MG, et al (2009): Time’s arrow flies like a bird: two paradoxes for avian circadian biology. Gen Comp Endocrinol, 163, 109–116.
- Csernus V, Mess B (2003): Biorhythms and pineal gland. Neuro Endocrinol Lett, 24, 404-411.
- Egbuniwe C, Ayo J (2016): Physiological roles of avian eyes in light perception and their response to photoperiodicity. Worlds Poult Sci J, 72, 605-614.
- Farag H, Ali Hassan R, Al Lehyani SH (2020): Protective effect of melatonin on hemoglobin damage induced by gamma irradiation. JETIR, 7, 320-325. Available at: http://www.jetir.org/papers/JETIR1912042.pdf (Accessed 13 September 2020).
- Gross WB, Siegel HS (1983): Evaluation of the heterophil/lymphocyte ratio as a measure of stress in chickens. Avian Dis, 27, 972-979.
- Moore CB, Siopes TD (2000): Effects of light conditions and melatonin supplementation on the cellular and humoral immune responses in Japanese quail Coturnix coturnix japonica. Gen Comp Endocrinol, 119, 95–104.
- Mund MD, Riaz M, Mirza MA, et al (2019): Effect of dietary tryptophan supplementation on growth performance, immune response and anti‐oxidant status of broiler chickens from 7 to 21 days. Vet Med Sci, 6, 48-53.
- Olanrewaju H, Thaxton J, Dozier W, et al (2006): A review of lighting programs for broiler production. Int J Poul Sci, 5, 301-308.
- Pattison M (2008): Poultry Diseases. Elsevier Health Sciences, Amsterdam.
- Reiter R, Tan D, Galano A (2014): Melatonin: Exceeding expectations. Physiol, 29, 325-333.
- RSPCA (2017): RSPCA welfare standards for meat chickens. Available at: https://science.rspca.org.uk/ sciencegroup/farmanimals/standards/chickens (Accessed 12 June 2020).
- Rusov Č (2002): Hematology of birds. Scientific Veterinary Institute of Serbia (NIVS). Belgrade.
- Scanes C, Lauterio T (1984): Growth hormone: Its physiology and control. J Exp Zool, 232, 443-452.
- Singh R., Cook N., Cheng K. M., et al (2009): Invasive and noninvasive measurement of stress in laying hens kept in conventional cages and in floor pens. Poult Sci, 88, 1346–1351.
- Sinkalu V (2012): Effect of melatonin on physiological responses of broiler chickens to continuous lighting, heat and road transportation stress during the hot-dry season. Doctoral Dissertation. Department of Physiology, Faculty of Veterinary medicine, Ahmadu Bello University, Zaria, Nigeria.
- Sun YY, Li YL, Li DL, et al (2017): Responses of broilers to the near-continuous lighting, constant 16-h lighting, and constant 16-h lighting with a 2-h night interruption. Livest Sci, 206, 135-140.
- Škrbić Z, Pavlovski Z, Lukić M, et al (2013): The role of light in broiler production. 222-231. In: Proceedings 10th International Symposium “Modern Trends in Livestock Production”, Belgrade.
- Talebi A, Asri-Rezaei S, Rozeh-Chai R, et al (2005): Comparative Studies on Haematological Values of Broiler Strains (Ross, Cobb, Arbor-acres and Arian). Int J Poult Sci, 4, 573-579.
- Tehrani A, Javanbakht J, Askari S, et al (2012): Haematological Studies on Broiler Chickens Fed with Different Levels of Artemia Urmiana. J Biotechnol Biomater, 2, 138.
- Weiss DJ, Wardrop JK (2011): Schalm's Veterinary Hematology. Sixth Edition. Wiley-Blackwell. Washington.
- Zavodnik IB, Domanski AV, Lapshina EA, et al (2006): Melatonin directly scavenges free radicals generated in red blood cells and a cell-free system: Chemiluminescence measurements and theoretical calculations. Life Sci, 79, 391-400.
- Zeman M, Buyse J, Lamošova D, et al (1999): Role of melatonin in the control of growth and growth hormone secretion in poultry. Appl Anim Behav Sci, 17, 199-207.
- Zeman M, Herichova I (2011): Circadian melatonin production develops faster in birds than in mammals. Gen Comp Endocrinol, 172, 23-30.
- Zhao D, Yu Y, Shen Y, et al (2019): Melatonin synthesis and function: Evolutionary history in animals and plants. Front Endocrinol, 10, 249.
- Zheng L, Ma Y, Gu L, et al (2013): Growth performance, antioxidant status, and nonspecific immunity in broilers under different lighting regimes. J Appl Poult Res, 22, 798-807.
There are 41 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Article |
| Authors | |
| Project Number | 451-03-68/2020-14/200116 and 451-03-68/2020-14/200022 |
| Publication Date | September 30, 2022 |
| Published in Issue | Year 2022 |