Abstract
Bu olguda pektoral bölgesinde şişlik şikayeti bulunan 5.5 yaşlı, melez, erkek bir köpekte ter bezi karsinomu ile birlikte seyreden plazmasitom olgusu tanımlandı. Pektoral bölgeden alınan biyopsi materyali makroskobik olarak, 3x5x3 cm boyutlarında, 12 gr ağırlığında, üzeri deriyle kaplı, elastik kıvamlı olup, üst yüzünde yaklaşık 2 cm çapında ülserli bir alan görüldü. Kesiti multilobuler görünümde, yer yer içlerinde seröz bir sıvının olduğu kistik yapılar bulunmaktaydı. Biyopsi materyali rutin doku takibinden sonra Hematoksilen eosin (HE) ile boyandı. Histolojik olarak, yuvarlaktan ovale kadar değişen şekillerde, hiperkromatik çekirdekli, belirgin çekirdekcikli anaplazik ter bezi epitel hücrelerinden oluşan bez yapıları görüldü. Bu bez yapılarının arasında ise çok sayıda anaplazik özellikler gösteren plazma hücrelerinin olduğu dikkati çekti
Keywords
References
- Bahl A, Sharma D, Julka P, Das A, Rath G (2006): Sweat gland carcinoma with lung metastases. J Cancer Res Ther, 4, 209-211.
- Canlas MS, Dillon ML, Loughrin JJ (1979): Primary cutaneous plasmacytoma. Arch Dermatol, 115, 722-724.
- Gibson NR, Ness MG, McNeil PE (1997): Malignant articular plasmacytoma in two dogs. Vet Rec, 141, 197- 200.
- Goldschmidt MH, Hendrick MJ (2002): Tumors of the Skin and Soft Tissues. 45-117. In: DJ Meuton, (ed), Tumors in Domestic Animals. 4 th ed. Iowa State Press, Iowa.
- Kalaher KM, Anderson WI, Scott DW (1990): Neoplasms of the apocrine sweat glands in 44 dogs and 10 cats. Vet Rec, 127, 400-403.
- Pagnoncelli M, Martins DB, França RT, Lopes STA, Zanette RA, Mazzanti CM (2012): Fine-needle aspiration cytology of the canine apocrine sweat gland carcinoma. Comp Clin Pathol, 21, 627-629.
- Rusbridge C, Wheeler SJ, Lamb CR, Page RL, Carmichael S, Brearley MJ, Bjornson AP (1999): Vertebral plasma cell tumors in 8 dogs. J Vet Intern Med, 13, 126-133.
- Simko E, Wilcock BP, Yager JA (2003): A retrospective study of 44 canine apocrine sweat gland adenocarcinomas. Can Vet J, 44, 38-42.
- Souza CM, Damasceno KA, Gamba CO, Campos LC, Campos CB, Cassali GD (2011): Canine sweat gland mixed tumor. Acta Scientiae Veterinariae, 39, 1001.
- Weiss E, Frese K (1974): Tumours of the skin. In: BULLETIN of The World Health Organization, International Histological Classification of Tumours of Domestic Animals. WHO, Geneve, 50, 79-100.
Abstract
In this case study, sweat gland carcinoma associated with plasmacytoma was described in a 5.5-year-old male mongrel dog suffering from a swelling in the pectoral region. Macroscopically, the biopsy material taken from the pectoral region was 3x5x3 cm in size, 12 g in weight, covered with skin and of elastic consistency, and presented with an ulcerous area nearly 2 cm in diameter on the upper surface. The cross-section had a multilobular appearance and contained cystic structures, which partly contained a serous fluid. Following routine tissue processing, the biopsy material was stained with haematoxylin-eosin (HE). Histologically, glandular structures composed of anaplastic sweat gland epithelial cells, which varied from round to oval in shape and contained hyperchromatic nuclei with evident nucleoli, were observed. In-between these glandular structures many anaplastic plasma cells existed
Keywords
References
- Bahl A, Sharma D, Julka P, Das A, Rath G (2006): Sweat gland carcinoma with lung metastases. J Cancer Res Ther, 4, 209-211.
- Canlas MS, Dillon ML, Loughrin JJ (1979): Primary cutaneous plasmacytoma. Arch Dermatol, 115, 722-724.
- Gibson NR, Ness MG, McNeil PE (1997): Malignant articular plasmacytoma in two dogs. Vet Rec, 141, 197- 200.
- Goldschmidt MH, Hendrick MJ (2002): Tumors of the Skin and Soft Tissues. 45-117. In: DJ Meuton, (ed), Tumors in Domestic Animals. 4 th ed. Iowa State Press, Iowa.
- Kalaher KM, Anderson WI, Scott DW (1990): Neoplasms of the apocrine sweat glands in 44 dogs and 10 cats. Vet Rec, 127, 400-403.
- Pagnoncelli M, Martins DB, França RT, Lopes STA, Zanette RA, Mazzanti CM (2012): Fine-needle aspiration cytology of the canine apocrine sweat gland carcinoma. Comp Clin Pathol, 21, 627-629.
- Rusbridge C, Wheeler SJ, Lamb CR, Page RL, Carmichael S, Brearley MJ, Bjornson AP (1999): Vertebral plasma cell tumors in 8 dogs. J Vet Intern Med, 13, 126-133.
- Simko E, Wilcock BP, Yager JA (2003): A retrospective study of 44 canine apocrine sweat gland adenocarcinomas. Can Vet J, 44, 38-42.
- Souza CM, Damasceno KA, Gamba CO, Campos LC, Campos CB, Cassali GD (2011): Canine sweat gland mixed tumor. Acta Scientiae Veterinariae, 39, 1001.
- Weiss E, Frese K (1974): Tumours of the skin. In: BULLETIN of The World Health Organization, International Histological Classification of Tumours of Domestic Animals. WHO, Geneve, 50, 79-100.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Other ID | JA64GB84TC |
| Journal Section | Research Article |
| Authors | |
| Publication Date | December 1, 2014 |
| Published in Issue | Year 2014Volume: 61 Issue: 4 |