Abstract
Ferrets are induced ovulators and estrus may last up to 5-6 months resulting in estrogen-induced bone marrow suppression and severe aplastic anaemia that can result in death. Spaying non-breeding females at 6-8 months of age, prior to or during first two weeks of estrus, is recommended as a preventative measure. On 1st of March 2010, an 8-month old domestic ferret weighing 920 g was introduced with a 5 day history of inguinal mass and request of sexing. Clinical examination revealed a 1.6 cm vulvar swelling, a characteristic of estrus in ferrets. Estrus was confirmed by vaginal exfoliative cytology. Because the ferret was housed alone and was not intended for breeding ovariohysterectomy (OHE) was recommended. OHE was performed through a ventral midline incision under general anaesthesia. No complications were observed and the vulva regressed to its normal size in 3 weeks. The objectives of this study were to highlight the importance of OHE in prevention of estrogen-induced bone marrow suppression in ferrets. Critical aspects of the surgical technique were also discussed
References
- Ball RS (2006): Issues to consider for preparing ferrets as research subjects in the laboratory. ILAR J, 47, 348-357.
- Lindeberg H (2008): Reproduction of the female ferret. Reprod Domest Anim, 43,150-156.
- Crossmon G (1937): A modification of Mallory’s connective tissue stain with a discussion of the principles involved. Anat Rec, 69, 33-38.
- Murphy BD (1989): Reproductive physiology of female mustelids. 107-123. In: Seal US, Thorne ET, Bogan MA, Anderson SH (eds), Conservation Biology and the Black- footed Ferret. New Haven, CT,: Yale University Press.
- Orcutt KJ (2003): Ferret urogenital diseases. Vet Clin Exot Anim, 6, 113-138.
- Eshar D, Wyre NR (2010): Ovariohysterectomy in ferrets. Lab Anim (NY), 39, 140-141.
- Schoemaker NJ (2003): Hyperadrenocorticism in ferrets. PhD thesis, Utrecht University.
- Fox JG, Bell JA (1998): Growth reproduction and breeding. 211-228. In: Fox JG, editor. Biology and diseases of the ferret. 2nd ed. Baltimore: Lippincott Williams and Wilkins.
- Castanheira de Matos RE, Morrisey JK (2006): Common procedures in the pet ferret. Vet Clin Exot Anim, 9, 347-365.
- Hammond J, Walton A (1934): Notes on ovulation and fertilization in the ferret. J Exp Biol, 14, 307-319.
Abstract
Provake ovulasyonun görüldüğü dişi gelinciklerde, östrus 5-6 aya kadar uzayabilmekte ve bu durum kemik iliği baskılanması ve ölümcül aplastik anemi ile sonuçlanabilmektedir. Koruyucu amaçla; çiftleştirilmeyecek dişilerin 6-8 aylık yaşta, çiftleşme dönemi öncesinde veya östrusun ilk 2 haftası içerisinde kısırlaştırılması önerilmektedir. 1 Mart 2010 tarihinde 920 gr ağırlığında, 8 aylık bir gelincik inguinal bölgede 5 gündür süregelen şişkinlik ve cinsiyet tayini istemiyle getirildi. Klinik muayenede, vulvada östrusa özgü pembe renkli 1.6 cm çapında şişkinlik belirlendi. Östrus vaginal eksfolyatif sitoloji ile doğrulandı. Hayvanın yalnız barındırılması ve yavru istenmemesi nedeniyle ovaryohisterektomi (OHE) önerildi. Genel anestezi altında ventral orta hat ensizyonu ile OHE gerçekleştirildi. Herhangi bir komplikasyonla karşılaşılmadı ve vulva 3 hafta içerisinde regrese oldu. Bu çalışmanın başlıca amacı OHE’nin östrojene bağlı kemik iliği baskılanmasının engellenmesindeki önemine dikkat çekmektir. Ayrıca, cerrahi tekniğe ilişkin önemli noktalara değinilmeye çalışılmıştır
References
- Ball RS (2006): Issues to consider for preparing ferrets as research subjects in the laboratory. ILAR J, 47, 348-357.
- Lindeberg H (2008): Reproduction of the female ferret. Reprod Domest Anim, 43,150-156.
- Crossmon G (1937): A modification of Mallory’s connective tissue stain with a discussion of the principles involved. Anat Rec, 69, 33-38.
- Murphy BD (1989): Reproductive physiology of female mustelids. 107-123. In: Seal US, Thorne ET, Bogan MA, Anderson SH (eds), Conservation Biology and the Black- footed Ferret. New Haven, CT,: Yale University Press.
- Orcutt KJ (2003): Ferret urogenital diseases. Vet Clin Exot Anim, 6, 113-138.
- Eshar D, Wyre NR (2010): Ovariohysterectomy in ferrets. Lab Anim (NY), 39, 140-141.
- Schoemaker NJ (2003): Hyperadrenocorticism in ferrets. PhD thesis, Utrecht University.
- Fox JG, Bell JA (1998): Growth reproduction and breeding. 211-228. In: Fox JG, editor. Biology and diseases of the ferret. 2nd ed. Baltimore: Lippincott Williams and Wilkins.
- Castanheira de Matos RE, Morrisey JK (2006): Common procedures in the pet ferret. Vet Clin Exot Anim, 9, 347-365.
- Hammond J, Walton A (1934): Notes on ovulation and fertilization in the ferret. J Exp Biol, 14, 307-319.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Other ID | JA74SA89JK |
| Journal Section | Research Article |
| Authors | |
| Publication Date | December 1, 2012 |
| Published in Issue | Year 2012Volume: 59 Issue: 4 |