Abstract
In this study incidentally detected renal aplasia in right kidney and compensatory hypertrophy in left kidney have been defined with the anatomical and pathological findings in a 2 years old male crossbred cat which had suffered from infirmity, vomiting, anorexia and depression. In macroscopic examination, it was observed that the left kidney was located on the left side of the median line, at the ventral part of the transverse processes of the 1st – 4th lumbar vertebrae. The right kidney was at the right side of median line, ventral part of the transverse process of the 2nd lumbar vertebra. Left kidney had a yellow color and a firm consistency and also the cut sections were smooth. Besides, right kidney had a grayish-yellow color and the distinction between renal cortex and medulla in cut sections couldn’t be distinguished. As of anatomical location and morphology, no abnormality was observed in the other organs of the cat. In right kidney, tubular structures were recognized histopathologically in between intense collagen tissue. Numerous of vascular formations were found near to the renal capsule. In hypertrophic kidney, in many of the tubules, degenerative alterations were observed significantly. Microscopically the most of the glomeruli were enlarged with mesangial cell hyperplasia and filled completely the Bowman’s space. In the light of the detailed anatomical and pathological findings, the aim of this study was to make a contribution to such unilateral aplasia and compensatory hypertrophy cases that were rarely detected both in human and veterinary medicine
Keywords
References
- Acién P, Acién M, Sánchez-Ferrer M (2004): Complex malformations of the female genital tract. New types and revision of classification. Hum Reprod, 19, 2377–2384.
- Agut A, Fernandez del Palacio MJ, Laredo FG, Murciano J, Bayon A, Soler M (2002): Unilateral renal agenesis associated with additional congenital abnormalities of the urinary tract in a Pekingese bitch. J Small Anim Pract, 43, 32–35.
- Azizi S, Kheirandish R, Yazdanpour H (2010): Histopathologic features of a unilateral renal dysplasia in a cat (Felis domestica). Comp Clin Pathol, 19, 445–447
- Chang J, Jung JH, Yoon J, Choi MC, Park JH, Seo KM, Jeong SM (2008): Segmental aplasia of the uterine horn with ipsilateral renal agenesis in a cat. J Vet Med Sci, 70, 641–643.
- Hazıroğlu R, Milli ÜH (2001): Veteriner Patoloji. Cilt II. 2. Baskı. Medipres, Ankara.
- Hiraoka M, Tsukahara H, Ohshima Y, Kasuga K, Ishihara Y. Mayumi M (2002): Renal aplasia is the predominant cause of congenital solitary kidneys. Kidney Int, 61, 1840–1844.
- Kissane JM (1974): Development of the kidney and congenital malformations. 69-109. In: Hepstinstall RH (Ed), Pathology of the Kidney. Vol 1. Little, Brown and Co, Boston.
- Köküuslu C (1996): Genel Patoloji. 1. Baskı. Medisan Yayınevi, Ankara.
- Maxie MG, Newman SJ (2007): The urinary system. 425- 522. In: MG Maxie (Ed), Jubb, Kennedy & Palmer's Pathology of Domestic Animals. Vol 2. Saunders Elsevier, Philadelphia.
- Morita T, Michimae Y, Sawada M, Uemura T, Araki Y, Haruna A, Shimada A (2005): Renal dysplasia with unilateral renal agenesis in a dog. J Comp Pathol, 133, 64- 67.
- Taney KG, Moore KW, Carro T, Spencer C (2003): Bilateral ectopic ureters in a male dog with unilateral renal agenesis. J Am Vet Med Assoc, 223, 817–820.
- Wadsworth PF, Squires PF (1980): Renal aplasia and hypoplasia in the rhesus monkey (Macaca mulatta). Lab Anim, 14, 1-2. Geliş tarihi: 11.10.2010 / Kabul tarihi: 24.03.2011 Adress for correspondence Lect.Off.Dr. Okan Ekim Department of Anatomy, Faculty of Veterinary Medicine, Ankara University, 06110, Dışkapı-Ankara/ TURKEY. Tel: +90312 3170315 Fax: +90312 3175559 e-mail: okanekim@yahoo.com
Abstract
Bu çalışmada, kusma, depresyon, anoreksi şikayetiyle gelen, 2 yaşlı, erkek, tekir bir kedide rastlantısal olarak karşılaşılan sağ böbrekte renal aplazi ile sol böbrekte hipertrofi olguları anatomopatolojik bulgularıyla tanımlanmıştır. Makroskobik incelemede; sol böbreğin median hattın sol tarafında, 1.-4. vertebrae lumbales’lerin, processus transversus’larının iz düşümü hizasına, sağ böbreğin ise median hattın sağında, 2. lumbal vertebra’nın processus transversus’unun ventral’ine yerleştiği görüldü. Sağ böbreğin grimsi-sarı renkte olup kesit yüzüne bakıldığında korteks-medulla ayrımının yapılamadığı göze çarparken, sol böbrek sarı renkte, sert kıvamda ve kesit yüzü düz olarak gözlendi. Hayvanın diğer organlarında konum ve anatomik yapı itibarı ile herhangi bir anormallik tespit edilmedi. Histopatolojik olarak aplazik böbrekte yoğun kollagen doku arasında tubulus taslakları dikkati çekti. Kapsüle yakın yerlerde çok miktarda damarsal oluşumlar tespit edildi. Hipertrofik böbrekte ise çok sayıda tubulusta dejeneratif değişiklikler ön plandaydı. İncelenen sahaların çoğunda, glomerulusların mezangiyal hücre hiperplazisi ile genişlediği ve Bowman boşluğunu doldurduğu dikkati çekti. Bu çalışmanın amacı; detaylı anatomik ve patolojik bulgular ışığında, gerek beşeri gerekse veteriner hekimlikte nadiren tespit edilen, bu tür unilateral aplazi ve kompenzatorik hipertrofi olgularına katkı sağlamaktır
Keywords
References
- Acién P, Acién M, Sánchez-Ferrer M (2004): Complex malformations of the female genital tract. New types and revision of classification. Hum Reprod, 19, 2377–2384.
- Agut A, Fernandez del Palacio MJ, Laredo FG, Murciano J, Bayon A, Soler M (2002): Unilateral renal agenesis associated with additional congenital abnormalities of the urinary tract in a Pekingese bitch. J Small Anim Pract, 43, 32–35.
- Azizi S, Kheirandish R, Yazdanpour H (2010): Histopathologic features of a unilateral renal dysplasia in a cat (Felis domestica). Comp Clin Pathol, 19, 445–447
- Chang J, Jung JH, Yoon J, Choi MC, Park JH, Seo KM, Jeong SM (2008): Segmental aplasia of the uterine horn with ipsilateral renal agenesis in a cat. J Vet Med Sci, 70, 641–643.
- Hazıroğlu R, Milli ÜH (2001): Veteriner Patoloji. Cilt II. 2. Baskı. Medipres, Ankara.
- Hiraoka M, Tsukahara H, Ohshima Y, Kasuga K, Ishihara Y. Mayumi M (2002): Renal aplasia is the predominant cause of congenital solitary kidneys. Kidney Int, 61, 1840–1844.
- Kissane JM (1974): Development of the kidney and congenital malformations. 69-109. In: Hepstinstall RH (Ed), Pathology of the Kidney. Vol 1. Little, Brown and Co, Boston.
- Köküuslu C (1996): Genel Patoloji. 1. Baskı. Medisan Yayınevi, Ankara.
- Maxie MG, Newman SJ (2007): The urinary system. 425- 522. In: MG Maxie (Ed), Jubb, Kennedy & Palmer's Pathology of Domestic Animals. Vol 2. Saunders Elsevier, Philadelphia.
- Morita T, Michimae Y, Sawada M, Uemura T, Araki Y, Haruna A, Shimada A (2005): Renal dysplasia with unilateral renal agenesis in a dog. J Comp Pathol, 133, 64- 67.
- Taney KG, Moore KW, Carro T, Spencer C (2003): Bilateral ectopic ureters in a male dog with unilateral renal agenesis. J Am Vet Med Assoc, 223, 817–820.
- Wadsworth PF, Squires PF (1980): Renal aplasia and hypoplasia in the rhesus monkey (Macaca mulatta). Lab Anim, 14, 1-2. Geliş tarihi: 11.10.2010 / Kabul tarihi: 24.03.2011 Adress for correspondence Lect.Off.Dr. Okan Ekim Department of Anatomy, Faculty of Veterinary Medicine, Ankara University, 06110, Dışkapı-Ankara/ TURKEY. Tel: +90312 3170315 Fax: +90312 3175559 e-mail: okanekim@yahoo.com
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Other ID | JA58TM72KG |
| Journal Section | Research Article |
| Authors | |
| Publication Date | December 1, 2011 |
| Published in Issue | Year 2011Volume: 58 Issue: 4 |