Effect of PRID and GnRH combination on fertility parameters of heifers having inactive and active ovaries
Abstract
The aim of this study was to investigate the effect of PRID and GnRH combination on fertility parameters of heifers having inactive and active ovaries. Twenty-four heifers (Group I, inactive ovaries n:12 and Group II, active ovaries n:12) was to used as material of the study. All heifers were inserted PRID (1.55 g progesterone and 10 mg estradiol benzoate) intravaginally for 12 days. At the time of PRID removal, GnRH (0.0042 mg buserelin acetate 2.5 ml i.m.) administered. It was found that between the end of the treatment and time of behavioral estrus were 3.22±0.97 and 2.91±1.04 days in Group I and II, respectively. The differences between groups were statistically similar (p>0.05). Following removal PRID, the percentage of estrus detection were 75 % and 91.67 % for Group I and II, respectively. Pregnancy rates of the first service and the overall pregnancy rates were 33.33 % and 55.56 % for Group I and 45.45 % and 72.73 % for Group II. Intervals between the end of administration and conception were 15.2±18.57 and 13.0±15.7 days for Group I and II, respectively (p>0.05). As a result, it has been suggested that PRID and GnRH treatments in heifers with inactive and active ovaries were effective on reproductive performance, observation of estrus and regulation of estrus cycle
References
- Alaçam E (1997): İneklerde infertilite sorunu. 269-294. In: E, Alaçam (ed.), Evcil Hayvanlarda Doğum ve İnfertilite. Medisan Yayınları, Ankara.
- Alaçam E, Tekeli T, Çoyan K, Işık K (1993): İnaktif ovaryumlu düvelerde flurogestone asetat (FGA) ve gebe kısrak serum gonadotropini (PMSG) ile sağıtım girişimleri. Hay Araş Derg, 3, 110-112
- Arbeiter K, Pohl W (1986): Über die Anwendung der PRID-Spirale beim ovariellen Funktionsstörungen des Rindes (Feldversuch 2). Tierärztl Umsch, 41, 664-668.
- Arthur GH, Noakes DE, Pearson H (1989): Infertility in the cow: general considerations, anatomical, functional and managemental causes. 341-383. In: Veterinary Reproduction and Obstetrics. W.B. Saunders, London.
- Ball PJH, Peters AR (2004): Reproduction in Cattle. Blackwell Publishing. Great Britain.
- Bearden HJ, Fuquay JW (2000): Physiological and psychological causes for reproductive failure. 328-338. In: Applied Animal Reproduction, 5th ed. Prentice-Hall, Inc New Jersey.
- Dinç DA (2006): İneklerde reprodüktif verimliliği artırma programları. Vet Hek Dern Derg, 77 , 50-64.
- Ferry J (1997): Clinical management of anestrus. 285- 289. In: RS Youngquist (Ed), Current Therapy in Large Animal Theriogenology, WB Saunders Company, Philadelphia, Pennsylvania.
- Grunert E (1982): Zyklus und brunststörungen. In: E Grunert, M Berchtold (Ed), Fertilitätsstörungen beim weiblichen Rind, Verlag Parey, Berlin, Hamburg.
- Grunert E (1999): Steuerung der fortpflanzungs- funktionen mit hormonen. In: Grenert, E. Berchtold, M. (Ed): Fertilitätsstörungen beim weiblichen Rind, Verlag Parey, Berlin, Hamburg.
- Kaçar C, Aslan S (2004): İneklerde geç postpartum dönemde PRID ve CIDR-B ile PGF2α (İliren®) kombinasyonunun fertilite parametrelerine etkisi. Ankara Üniv Vet Fak Derg, 51, 19-23.
- Kuroiwa T, Ishibashi Aİ, Fukuda M, Kim S, Tanaka T, Kamomae H (2005): Estrus synchronization and conception rate after a progesterone releasing intravaginal device (PRID) treatment from early luteal phase in heifers. J Reprod Dev, 51, 669-673.
- López-Gatius F, Santolaria P, Yániz J, Rutllant J, López-Béjar M (2001): Persistent ovarian follicles in dairy cows: a therapeutic approach. Theriogenology, 56, 649-659.
- Macmillan K, Peterson AJ (1993): A new intravaginal progesterone releasing device for cattle (CIDR-B) for oestrus synchronization, increasing pregnancy rates and the treatment of post-partum anoestrus. Anim Reprod Sci, 33, 1-25.
- Markusfeld O (1987): Inactive ovaries in high-yielding dairy cows before service: aetiology and effect on conception. Vet Rec, 121, 149-153.
- Munro RK, Moore NW (1985): Effect of progesterone, oestradiol benzoate and cloprostenol on luteal function in the heifer. J Reprod Fert, 73, 353-359.
- Mwaanga ES, Janowski T (2000): Anoestrus in dairy cows: causes, prevalence and clinical forms. Reprod Dom Anim, 35, 193-200.
- Penny CD, Lowman BG, Scott NA, Scott PR (2000): Repeated oestrus synchronization of beef cows with progesterone implants and the effects of a gonadotrophin- releasing hormone agonist at implant insertion. Vet Rec, 146, 395-398.
- Salmanoğlu R (1998): İnaktif ovaryumlu ineklerde progestagen tedavisiyle birlikte PMSG veya GnRH uygulamalarının fertiliteye etkisi. Ankara Üniv Vet Fak Derg, 45, 145-150.
- Tjondronegoro S, Williamson P (1987): Effect of progesterone, intravaginal devices on synchronization of estrus in postpartum dairy cows. J Dairy Sci, 70, 2162- 2167.
- Xue L, Arbeiter K, Breitenfellner N (1984): Die repetierte transvaginale Progesteronmedikation zur Zyklusprovakation und Fertilitätsüberwachung beim Rind. Wien Tierärztl Mschr, 81, 380-388.
- Zonturlu AK, Atlı MO, Çetin H (2005): Anöstrus semptomu gösteren ineklerde PRID uygulamalarının çeşitli fertilite parametrelerine etkisi. Ankara Üniv Vet Fak Derg, 52, 161-163. Geliş tarihi: 29.01.2007 / Kabul tarihi: 16.04.2007
Abstract
Sunulan çalışmada, inaktif ve aktif ovaryumlu düvelerde PRID ve GnRH uygulamalarının bazı fertilite parametrelerine etkisinin araştırılması amaçlandı. Çalışmada, inaktif ovaryumlu (Grup I, n:12) ve aktif ovaryumlu (Grup II, n:12) toplam 24 adet düve materyal olarak kullanıldı. Grup I ve II’deki düvelere özel aplikatör yardımı ile 12 gün süreyle PRID (1.55 g progesteron ve 10 mg östradiol benzoat) intravaginal yolla uygulandı. PRID’in çıkarıldığı gün GnRH (0.0042 mg buserelin asetat 2.5 ml i.m.) enjeksiyonu yapıldı. Uygulama bitimi östrus görülme zamanı Grup I’de 3.22±0.97 ve Grup II’de 2.91±1.04 gün olarak tespit edildi. Her iki grup arasındaki fark istatistiksel olarak önemsiz bulundu (p>0.05). PRID uzaklaştırıldıktan sonra Grup I’de % 75 ve Grup II’de % 91.67 oranında östrus saptandı. İlk tohumlama ve tüm tohumlamalar (üç tohumlama) sonrası gebelik oranları sırasıyla, Grup I’de % 33.33 ve %55.56 oranında Grup II’de % 45.45 ve %72.73 oranında bulundu. Uygulama bitimi gebe kalma aralığı Grup I’de 15.2±18.57 gün, Grup II’de 13.0±15.7 gün olarak belirlendi (p>0.05). Sonuç olarak, inaktif ve aktif ovaryumlu düvelerde PRID+GnRH uygulamalarının siklusun düzenlenmesinde veya başlatılmasında, östrus görülmesinde ve fertilite üzerinde etkili olduğu kanısına varıldı
References
- Alaçam E (1997): İneklerde infertilite sorunu. 269-294. In: E, Alaçam (ed.), Evcil Hayvanlarda Doğum ve İnfertilite. Medisan Yayınları, Ankara.
- Alaçam E, Tekeli T, Çoyan K, Işık K (1993): İnaktif ovaryumlu düvelerde flurogestone asetat (FGA) ve gebe kısrak serum gonadotropini (PMSG) ile sağıtım girişimleri. Hay Araş Derg, 3, 110-112
- Arbeiter K, Pohl W (1986): Über die Anwendung der PRID-Spirale beim ovariellen Funktionsstörungen des Rindes (Feldversuch 2). Tierärztl Umsch, 41, 664-668.
- Arthur GH, Noakes DE, Pearson H (1989): Infertility in the cow: general considerations, anatomical, functional and managemental causes. 341-383. In: Veterinary Reproduction and Obstetrics. W.B. Saunders, London.
- Ball PJH, Peters AR (2004): Reproduction in Cattle. Blackwell Publishing. Great Britain.
- Bearden HJ, Fuquay JW (2000): Physiological and psychological causes for reproductive failure. 328-338. In: Applied Animal Reproduction, 5th ed. Prentice-Hall, Inc New Jersey.
- Dinç DA (2006): İneklerde reprodüktif verimliliği artırma programları. Vet Hek Dern Derg, 77 , 50-64.
- Ferry J (1997): Clinical management of anestrus. 285- 289. In: RS Youngquist (Ed), Current Therapy in Large Animal Theriogenology, WB Saunders Company, Philadelphia, Pennsylvania.
- Grunert E (1982): Zyklus und brunststörungen. In: E Grunert, M Berchtold (Ed), Fertilitätsstörungen beim weiblichen Rind, Verlag Parey, Berlin, Hamburg.
- Grunert E (1999): Steuerung der fortpflanzungs- funktionen mit hormonen. In: Grenert, E. Berchtold, M. (Ed): Fertilitätsstörungen beim weiblichen Rind, Verlag Parey, Berlin, Hamburg.
- Kaçar C, Aslan S (2004): İneklerde geç postpartum dönemde PRID ve CIDR-B ile PGF2α (İliren®) kombinasyonunun fertilite parametrelerine etkisi. Ankara Üniv Vet Fak Derg, 51, 19-23.
- Kuroiwa T, Ishibashi Aİ, Fukuda M, Kim S, Tanaka T, Kamomae H (2005): Estrus synchronization and conception rate after a progesterone releasing intravaginal device (PRID) treatment from early luteal phase in heifers. J Reprod Dev, 51, 669-673.
- López-Gatius F, Santolaria P, Yániz J, Rutllant J, López-Béjar M (2001): Persistent ovarian follicles in dairy cows: a therapeutic approach. Theriogenology, 56, 649-659.
- Macmillan K, Peterson AJ (1993): A new intravaginal progesterone releasing device for cattle (CIDR-B) for oestrus synchronization, increasing pregnancy rates and the treatment of post-partum anoestrus. Anim Reprod Sci, 33, 1-25.
- Markusfeld O (1987): Inactive ovaries in high-yielding dairy cows before service: aetiology and effect on conception. Vet Rec, 121, 149-153.
- Munro RK, Moore NW (1985): Effect of progesterone, oestradiol benzoate and cloprostenol on luteal function in the heifer. J Reprod Fert, 73, 353-359.
- Mwaanga ES, Janowski T (2000): Anoestrus in dairy cows: causes, prevalence and clinical forms. Reprod Dom Anim, 35, 193-200.
- Penny CD, Lowman BG, Scott NA, Scott PR (2000): Repeated oestrus synchronization of beef cows with progesterone implants and the effects of a gonadotrophin- releasing hormone agonist at implant insertion. Vet Rec, 146, 395-398.
- Salmanoğlu R (1998): İnaktif ovaryumlu ineklerde progestagen tedavisiyle birlikte PMSG veya GnRH uygulamalarının fertiliteye etkisi. Ankara Üniv Vet Fak Derg, 45, 145-150.
- Tjondronegoro S, Williamson P (1987): Effect of progesterone, intravaginal devices on synchronization of estrus in postpartum dairy cows. J Dairy Sci, 70, 2162- 2167.
- Xue L, Arbeiter K, Breitenfellner N (1984): Die repetierte transvaginale Progesteronmedikation zur Zyklusprovakation und Fertilitätsüberwachung beim Rind. Wien Tierärztl Mschr, 81, 380-388.
- Zonturlu AK, Atlı MO, Çetin H (2005): Anöstrus semptomu gösteren ineklerde PRID uygulamalarının çeşitli fertilite parametrelerine etkisi. Ankara Üniv Vet Fak Derg, 52, 161-163. Geliş tarihi: 29.01.2007 / Kabul tarihi: 16.04.2007
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Article |
| Authors | |
| Publication Date | June 1, 2008 |
| Published in Issue | Year 2008Volume: 55 Issue: 1 |