Abstract
Bu raporda, 8 yaşlı yarım kan İngiliz bir kısrağın ventral abdomen bölgesinde saptanan miks sarkoid olgusu klinik ve patolojik bulguları ile tanımlanmıştır. Tümör, 6x4x3 cm ölçülerinde, yüzeyi ülserli ve kanamalı, kılsız deri ile örtülü deri yüzeyden taşkın diskoid şekilli bir kitleden ibaretti. Histopatolojik incelemede, epidermiste yaygın ülser alanları, hiperplazi, ortokeratotik hiperkeratoz ve yer yer epitelyal incelmeler dikkati çekti. Nadiren akantozis ve kistik kıl folliküllerine rastlandı. Dermiste yumak şeklinde kıvrımlar oluşturan fibroblast benzeri iğ ve çomak şekilli hücre proliferasyonları görüldü. Farklı sarkoid tiplerine ait klinik ve histopatolojik bulgular gözlenen bu tümöre miks sarkoid tanısı konuldu
Keywords
References
- Brostrom H (1995): A clinical and epidemiological study in relation to equine leucocyte antigens (ELA). Acta Vet Scand, 36, 223-236
- Carstanjen B, Jordon P, Lepage OM (1997): Carbon dioxide laser as a surgical instrument for sarcoid therapy. A retrospective study on 60 cases. Can Vet J, 38, 773-776
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- Martens A, De Moor A, Demeulemeester J, Ducatelle R (2000) : Histopathological characteristic of five clinical types of equine sarcoid. Res Vet Sci, 69, 295-300
- Martens A, De Moor A, Vlaminck L, Pille F, Steenhaut M (2001). Evaluation of excision, cryosurgery and local BCG vaccination for the treatment of equine sarcoids. Vet Rec, 149, 665-669
- Mohammed HO, Rebhun WC, Antczak DF (1992). Factors associated with the risk of developing sarcoid tumours in horses. Equine Vet J, 24, 165-168
- Nixon C, Chambers G, Ellsmore V, Campo MS, Burr P, Argyle DJ, Reid SW, Nasir L (2005). Expression of cell cycle associated proteins cyclin A, CDK-2, p27kip1 and p53 in equine sarcoids. Cancer Lett, 221, 237-245.
- Theon AP, Pascoe JR, Carlson GP, Krag DN (1993): Intratumoral chemotherapy with cisplatin in oily emulsion in horses. JAVMA, 202, 261-267. Geliş tarihi: 29.12.2005 / Kabul tarihi: 20.01.2006
Abstract
In this report, a mixed sarcoid case detected on the ventral abdomen region of an 8 year-old Throughbreed horse was described with clinical and pathological findings. The tumor was 6x4x3 cm in size, discoid in shape and contained ulcerative and haemorrhagic areas on the hairless skin. Histopathologically, widespread ulceration, hyperplasia, orthokeratotic hyperkeratosis and thinning of the epidermis were observed. Occasionally, acanthosis and follicular cysts were also detected. Whorls of fibroblast-like spindle and spheroidal cell proliferations were seen in dermis. This tumor was diagnosed as mixed sarcoid because of the clinical and histopathological findings consistent with different sarcoid types
Keywords
References
- Brostrom H (1995): A clinical and epidemiological study in relation to equine leucocyte antigens (ELA). Acta Vet Scand, 36, 223-236
- Carstanjen B, Jordon P, Lepage OM (1997): Carbon dioxide laser as a surgical instrument for sarcoid therapy. A retrospective study on 60 cases. Can Vet J, 38, 773-776
- Chambers G, Ellsmore VA, O’Brien PM, Reid SW, Love S, Campo MS, Nasir L (2003): Sequence variants of bovine papillomavirus E5 detected in equine sarcoids. Virus Res, 96, 241-245
- Yager JA, Scott DW (1993): The skin and appendages. In: Pathology of Domestic Animals, ed. Jubb KVF, Kennedy PC, Palmer N, 4th ed., vol. 1, Academic Press, San Diego, CA
- Kinnunen RE, Tallberg T, Stenback H, Sarna S (1999): Equine sarcoid tumour treated by autogenous tumour vaccine. Anticancer Res, 19, 3367-3374
- Knottenbelt DC, Matthews JB (2001): A positive step forwards in the diagnosis of equine sarcoid. Vet J, 161, 224-226
- Martens A, De Moor A, Demeulemeester J, Ducatelle R (2000) : Histopathological characteristic of five clinical types of equine sarcoid. Res Vet Sci, 69, 295-300
- Martens A, De Moor A, Vlaminck L, Pille F, Steenhaut M (2001). Evaluation of excision, cryosurgery and local BCG vaccination for the treatment of equine sarcoids. Vet Rec, 149, 665-669
- Mohammed HO, Rebhun WC, Antczak DF (1992). Factors associated with the risk of developing sarcoid tumours in horses. Equine Vet J, 24, 165-168
- Nixon C, Chambers G, Ellsmore V, Campo MS, Burr P, Argyle DJ, Reid SW, Nasir L (2005). Expression of cell cycle associated proteins cyclin A, CDK-2, p27kip1 and p53 in equine sarcoids. Cancer Lett, 221, 237-245.
- Theon AP, Pascoe JR, Carlson GP, Krag DN (1993): Intratumoral chemotherapy with cisplatin in oily emulsion in horses. JAVMA, 202, 261-267. Geliş tarihi: 29.12.2005 / Kabul tarihi: 20.01.2006
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Article |
| Authors | |
| Publication Date | September 1, 2006 |
| Published in Issue | Year 2006Volume: 53 Issue: 3 |