Research Article
Year 2020,
Volume: 67 Issue: 1, 87 - 94, 26.12.2019
Abstract
References
- 1. Agarwal A, Gupta S, Sharma RK (2005): Role of oxidative stress in female reproduction. Reprod Biol Endocrinol, 3, 28.
- 2. Alaçam E, Ay SS, Saban E (2009): İnek, koyun ve köpeklerde değişik radioimmunoassay progesterone ölçüm kitlerinin reprodüktif sürecin farklı evrelerinde değerlendirilmesi. Ankara Univ Vet Fak Derg, 56, 37-41.
- 3. Bladowska K, Baranski W, Janowski TE (2018): Preovulatory progesterone secretion terminates the duration of reproductive behavior during heat in the bitch. Pol J Vet Sci, 21, 615-622.
- 4. Circu ML, Aw TY (2010): Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med, 48, 749-62.
- 5. Concannon PW (2011): Reproductive cycles of the domestic bitch. Anim Reprod Sci, 124, 200-210.
- 6. Çamkerten İ, Çamkerten G, Erdoğan H, et al (2019): Serum thiol disulphide levels among sheep with sarcoptic mange. Kafkas Univ Vet Fak Derg, 25, 865-868.
- 7. Delgobo M, Agnes JP, Gonçalves RM, et al (2019): N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms. J Nutr Biochem, 67, 190-200.
- 8. Erel O (2004): A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem, 37, 277-285.
- 9. Erel O (2005): A new automated colorimetric method for measuring total oxidant status. Clin Biochem, 38, 1103-1111.
- 10. Erel O, Neselioglu S (2014): A novel and automated assay for thiol/disulphide homeostasis. Clin Biochem, 47, 326-332.
- 11. Hollinshead FK, Hanlon DW (2019): Normal progesterone profiles during estrus in the bitch: A prospective analysis of 1420 estrous cycles. Theriogenology, 125, 37-42.
- 12. Hossein MS, Kim MK, Jang G, et al (2007): Effects of thiol compounds on in vitro maturation of canine oocytes collected from different reproductive stages. Mol Reprod Dev, 74, 1213-1220.
- 13. Lázár L (2012): The Role of Oxidative Stress in Female Reproduction and Pregnancy, Oxidative Stress and Diseases. InTech Europe.
- 14. Lu J, Wang Z, Cao J, et al (2018): A novel and compact review on the role of oxidative stress in female reproduction. Reprod Biol Endocrinol, 16: 80.
- 15. Pech LGM, Caballero-Chacon SDC, Guarner-Lans V, et al (2019): Effect of oophorosalpingohysterectomy on serum antioxidant enzymes in female dogs. Sci Rep, 9: 9674.
- 16. Root Kustritz MV (2010): How Do I Use Progesterone and Other Measures for Breeding Management? 97-100. In: MV Root Kustritz (Ed), Clinical Canine and Feline Reproduction: Evidence-Based Answers. Wiley-Blackwell Publishing, Iowa.
- 17. Root Kustritz MV (2012): Managing the reproductive cycle in the bitch. Vet Clin North Am Small Anim Pract, 42, 423-437.
- 18. Rizzo A, Roscino MA, Minoia G, et al (2009): Serum levels of reactive oxygen species (ROS) in the bitch. Immunopharmacol Immunotoxicol, 31, 310-313.
- 19. Rizzo A, Minoia G, Trisolini C, et al (2009): Reactive oxygen species (ROS): involvement in bovine follicular cysts etiopathogenesis. Immunopharmacol Immunotoxicol, 31, 631-635.
- 20. Rizzo A, Roscino MT, Binetti F, et al (2012): Roles of reactive oxygen species in female reproduction. Reprod Dom Anim, 47, 344-352.
- 21. Sato J, Nasu M, Tsuchitani M (2016): Comparative histopathology of the estrous or menstrual cycle in laboratory animals. J Toxicol Pathol, 29, 155-162.
- 22. Senger PL (2005): Reproductive Cyclicity – Terminology and Basic Concepts 144-163. In: Senger PL (Ed), Pathways to Pregnancy and Parturition. Current Conception, Inc. Washington.
- 23. Shkolnik K, Tadmor A, Ben-Dor S, Nevo N, Galiani D, Dekel N (2011): Reactive oxygen species are indispensable in ovulation. Proc Natl Acad Sci USA, 108, 1462-1467.
- 24. Sugino N (2006): Roles of reactive oxygen species in the corpus luteum. Anim Sci J, 77, 556-565.
- 25. Takahashi M, Nagai T, Hamano S, et al (1993): Effect of thiol compound on in vitro development and intracellular glutathione content of bovine embryos. Biol Reprod, 49, 228-232.
- 26. Tropea A, Miceli F, Minici F, et al (2006): Regulation of vascular endothelial growth factor synthesis and release by human luteal cells in vitro. J Clin Endocrinol Metab, 91, 2303-2309.
- 27. Unfer TC, Figueiredo CG, Zanchi MM, et al (2015): Estrogen plus progestin increase superoxide dismutase and total antioxidant capacity in postmenopausal women. Climacteric, 18, 379-388.
- 28. Van Cruchten S, Van den Broeck W, D’haeseleer M, et al (2004): Proliferation patterns in the canine endometrium during the estrous cycle. Theriogenology, 62, 631-641.
The evaluation of the oxidative stress index of reproductive tissues and serum thiol/disulphide homeostasis during estrous cycle in bitches
Abstract
The aim of this study was firstly to determine
the relationship between estrous cycle and oxidative stress in reproductive
tissues in bitches. This research was performed in twenty-nine healthy bitches
from different breeds and of varied ages (the range was 2-5 years) that were
brought to the clinic for routine ovariohysterectomy. The stages of estrous
cycle were detected using by vaginal cytology, blood progesterone level and
histological findings. Ovarian, oviduct and uterine tissues were taken into Eppendorf
tubes for oxidative stress index and stored at -80°C until analyses. Also, another
part of these tissues were fixed in 10% formalin solution. There were no
significant differences (P > 0.05) among total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) values in the reproductive tissues in
concerning estrous cycle stages. However, there were remarkable correlations
between oxidative stress parameters and reproductive tissues in different
estrus stages in bitches. In
conclusion, the physiological values of TAS and TOS concentration, and OSI in
the ovarian, oviduct and uterine tissues during estrous cycle were firstly
defined in this article. The serum thiol/disulphide homeostasis was also
determined in the estrous cycle of bitches. We have found that there are
remarkable variations of oxidative stress balance in the ovary, oviduct and
uterus concurrently, during estrous cycle in the bitches. Besides, significant
correlations between oxidative stress parameters and estrous cycle stages in
the reproductive tissues were observed in the present study.
References
- 1. Agarwal A, Gupta S, Sharma RK (2005): Role of oxidative stress in female reproduction. Reprod Biol Endocrinol, 3, 28.
- 2. Alaçam E, Ay SS, Saban E (2009): İnek, koyun ve köpeklerde değişik radioimmunoassay progesterone ölçüm kitlerinin reprodüktif sürecin farklı evrelerinde değerlendirilmesi. Ankara Univ Vet Fak Derg, 56, 37-41.
- 3. Bladowska K, Baranski W, Janowski TE (2018): Preovulatory progesterone secretion terminates the duration of reproductive behavior during heat in the bitch. Pol J Vet Sci, 21, 615-622.
- 4. Circu ML, Aw TY (2010): Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med, 48, 749-62.
- 5. Concannon PW (2011): Reproductive cycles of the domestic bitch. Anim Reprod Sci, 124, 200-210.
- 6. Çamkerten İ, Çamkerten G, Erdoğan H, et al (2019): Serum thiol disulphide levels among sheep with sarcoptic mange. Kafkas Univ Vet Fak Derg, 25, 865-868.
- 7. Delgobo M, Agnes JP, Gonçalves RM, et al (2019): N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms. J Nutr Biochem, 67, 190-200.
- 8. Erel O (2004): A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem, 37, 277-285.
- 9. Erel O (2005): A new automated colorimetric method for measuring total oxidant status. Clin Biochem, 38, 1103-1111.
- 10. Erel O, Neselioglu S (2014): A novel and automated assay for thiol/disulphide homeostasis. Clin Biochem, 47, 326-332.
- 11. Hollinshead FK, Hanlon DW (2019): Normal progesterone profiles during estrus in the bitch: A prospective analysis of 1420 estrous cycles. Theriogenology, 125, 37-42.
- 12. Hossein MS, Kim MK, Jang G, et al (2007): Effects of thiol compounds on in vitro maturation of canine oocytes collected from different reproductive stages. Mol Reprod Dev, 74, 1213-1220.
- 13. Lázár L (2012): The Role of Oxidative Stress in Female Reproduction and Pregnancy, Oxidative Stress and Diseases. InTech Europe.
- 14. Lu J, Wang Z, Cao J, et al (2018): A novel and compact review on the role of oxidative stress in female reproduction. Reprod Biol Endocrinol, 16: 80.
- 15. Pech LGM, Caballero-Chacon SDC, Guarner-Lans V, et al (2019): Effect of oophorosalpingohysterectomy on serum antioxidant enzymes in female dogs. Sci Rep, 9: 9674.
- 16. Root Kustritz MV (2010): How Do I Use Progesterone and Other Measures for Breeding Management? 97-100. In: MV Root Kustritz (Ed), Clinical Canine and Feline Reproduction: Evidence-Based Answers. Wiley-Blackwell Publishing, Iowa.
- 17. Root Kustritz MV (2012): Managing the reproductive cycle in the bitch. Vet Clin North Am Small Anim Pract, 42, 423-437.
- 18. Rizzo A, Roscino MA, Minoia G, et al (2009): Serum levels of reactive oxygen species (ROS) in the bitch. Immunopharmacol Immunotoxicol, 31, 310-313.
- 19. Rizzo A, Minoia G, Trisolini C, et al (2009): Reactive oxygen species (ROS): involvement in bovine follicular cysts etiopathogenesis. Immunopharmacol Immunotoxicol, 31, 631-635.
- 20. Rizzo A, Roscino MT, Binetti F, et al (2012): Roles of reactive oxygen species in female reproduction. Reprod Dom Anim, 47, 344-352.
- 21. Sato J, Nasu M, Tsuchitani M (2016): Comparative histopathology of the estrous or menstrual cycle in laboratory animals. J Toxicol Pathol, 29, 155-162.
- 22. Senger PL (2005): Reproductive Cyclicity – Terminology and Basic Concepts 144-163. In: Senger PL (Ed), Pathways to Pregnancy and Parturition. Current Conception, Inc. Washington.
- 23. Shkolnik K, Tadmor A, Ben-Dor S, Nevo N, Galiani D, Dekel N (2011): Reactive oxygen species are indispensable in ovulation. Proc Natl Acad Sci USA, 108, 1462-1467.
- 24. Sugino N (2006): Roles of reactive oxygen species in the corpus luteum. Anim Sci J, 77, 556-565.
- 25. Takahashi M, Nagai T, Hamano S, et al (1993): Effect of thiol compound on in vitro development and intracellular glutathione content of bovine embryos. Biol Reprod, 49, 228-232.
- 26. Tropea A, Miceli F, Minici F, et al (2006): Regulation of vascular endothelial growth factor synthesis and release by human luteal cells in vitro. J Clin Endocrinol Metab, 91, 2303-2309.
- 27. Unfer TC, Figueiredo CG, Zanchi MM, et al (2015): Estrogen plus progestin increase superoxide dismutase and total antioxidant capacity in postmenopausal women. Climacteric, 18, 379-388.
- 28. Van Cruchten S, Van den Broeck W, D’haeseleer M, et al (2004): Proliferation patterns in the canine endometrium during the estrous cycle. Theriogenology, 62, 631-641.
There are 28 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Articles |
| Authors | |
| Publication Date | December 26, 2019 |
| Published in Issue | Year 2020Volume: 67 Issue: 1 |