Research Article
Year 2018,
Volume: 65 Issue: 4, 379 - 386, 09.11.2018
Abstract
References
- 1. Belova S, Wilhelm S, Linek M et al. (2012): Factors affecting allergen-specific IgE serum levels in cats. Can J Vet Res, 76, 45–51.
- 2. DeBoer DJ (2016): Feline Facial Dermatoses. South Euro Vet Conf, Granada, Spain, p. 45.
- 3. Diesel A, DeBoer DJ (2011): Serum allergen-specific immunoglobulin E in atopic and healthy cats: comparison of a rapid screening immunoassay and complete-panel analysis. Vet Dermatol, 22, 39-45.
- 4. Foster AP (2002): Diagnosing and treating feline atopy. Vet Med Us, 97, 226-229.
- 5. Foster AP, O'Dair HA (1993): Allergy Testing for Skin Disease in the Cat. In Vivo vs In Vitro Tests, 4, 111–115.
- 6. Foster AP, O'Dair HA, DeBoer DJ (1997): Allergenspecific IgG antibodies in cats with allergic skin disease. Res in Vet Sci, 63, 239-243.
- 7. Gilbert S, Halliwell REW (2005): The effects of endoparasitism on the immune response to orally administred antigen in cats. Vet Immunol Immunopath, 106, 113–120.
- 8. Gross TL, Ihrke PJ, Walder EJ et al. (2005): Spongiotic and vesicular diseases of the epidermis. Facial dermatitis of persian and himalayan cats. 112-115. In: LG Thelma, JI Peter, JW Emily, K Verena (Eds), Skin diseases of the dog and cat. Clinical and histopathologic diagnosis. Blackwell, Oxford.
- 9. Guaguere E, Prelaud PA (1999): Practical guide to feline dermatology. Merial, New York.
- 10. Guilford WG, Jones BR, Markwell PJ, et al. (2001): Food hypersensitivity in cats with chronic idiopathic gastrointestinal problems. J Vet Int Med, 15, 7–13.
- 11. Hamilton RG, Williams PB (2010): Human IgE antibody serology: A primer for the practicing North American allergist/immunologist. J Allergy Clin Immunol, 126, 33– 38.
- 12. Helmer M, Epe C, Mueller RS (2008): The effect of helminth administration on caninne AD: A pilot study. Vet Dermatol, 19, 33.
- 13. Hill PB, DeBoer DJ (2001): The ACVD task force on canine atopic dermatitis (IV): environmental allergens. Vet Immunol Immunopath, 81, 169–186.
- 14. Hobi S, Linek M, Marignac G, et al. (2011): Clinical characteristics and causes of pruritus in cats: a multicentre study on feline hypersensitivity-associated dermatoses. Vet Dermatol, 22, 406–413.
- 15. Kim HJ, Kang MH, Park HM (2011): Common allergens of atopic dermatitis in dogs: comparative findings based on intradermal tests. J Vet Sci, 12, 287–290.
- 16. Linden CC, Misiak RT, Wegienka G, et al. (2011): Zoratti EM. Analysis of allergen specific IgE cutpoints to cat and dog in the suburban Detroit Childhood Allergy Study. Ann Allergy Asthma Immunol, 106, 153–158.
- 17. Locke PH, Harvey RG, Mason IS (1993): Manual of small animal dermatology. British Small Animal Veterinary Association, Gloucestershire.
- 18. Loft KE, Pedersen K (2007): The presence of pollen and house dust mite allergen-specific IgE in serum of 15 SPF cats and prevalence of house dust mites allergens (Dermatophagoides pteronyssinus1, Dermatophagoides farinae1, and mite group 2) in their microenvironement. Vet Dermatol, 18, 184.
- 19. Loft KE, Rosser EJJ (2010): Group 1 and 2 Dermatophagoides house dust mite allergens in the microenvironment of cats. Vet Dermatol, 21, 152–158.
- 20. Marsella R, Girolomoni G (2009): Canine models of atopic dermatitis: a useful tool with untapped potential. J Invest Dermatol, 129, 2351-2357.
- 21. MCall CA, Steadmann KE, Bevier DE, et al. (1997): Correlation of feline IgE, determined by FcEpsilonR1alfabased ELISA technology, and IDST to Ctenocephalides felis salivary antigens in a feline model of flea bite allergic dermatitis. Suppl to Comp Cont Edu Pract Vet, 3, 29–32.
- 22. Moncayo AL, Cooper PJ (2006): Geohelminth infections: Impact on allergic diseases. International J Bioch Cell Biol, 38, 1031–1035.
- 23. Moriello KA (2001): Case report: Feline atopy in three littermates. Vet Dermatol, 12, 177-181.
- 24. Moriello KA, Masom I (1995): Handbook of small animal dermatology. Elsevier Science Ltd, Oxford.
- 25. Mueller RS, Janda J, Jensen-Jarolim E, et al. (2016): Allergens in veterinary medicine. Allergy, 71, 27-35.
- 26. Nagata M, Rosenkrantz W (2013): Cutaneous viral dermatoses in dogs and cats. Comp Cont Edu Pract Vet, 35, 1-6.
- 27. Roosje PJ, Koeman JP, Thepen T, et al. (2004): Mast cells and eosinophils in feline allergic dermatitis: a qualitative and quantitative analysis. J Comp Path, 131, 61– 69.
- 28. Sampson HA, Ho DG (1997): Relationship between foodspecific IgE concentrations and the risk of positive food challenges in children and adolescents. J Allergy Clin Immunol, 100, 444–451.
- 29. Schenkel M, Bigler B, Jungi T (2000): The use of fluorescein for intradermal skin testing in cats. Vet Dermatol, 11, 14-40.
- 30. Schleifer SG, Willemse T (2003): Evaluation of skin test reactivity to environmental allergens in healthy cats and cats with atopic dermatitis. Am J Vet Res, 64, 773–778.
- 31. Scott DW, Miller WH, Griffin CE (2001): Small Animal Dermatology. W.B. Saunders Company, Philadelphia.
- 32. Simpson A, Soderstrom L, Ahlstedt S, et al. (2005): IgE antibody quantification and the probability of wheeze in preschool children. J Allergy Clin Immunol, 116, 744–749.
- 33. Szczepanik M, Pomorska D, Wilkołek P (2016): Diagnostic approach to atopy in cats. Bullet Vet Inst Pul, 52, 477-480.
- 34. Taglinger K, Helps CR, Day MJ, et al. (2005): Measurement of serum immunoglobulin E (IgE) specific for house dust mite antigens in normal cats and cats with allergic skin disease. Vet Immunol Immunopath, 105, 85- 93.
- 35. Verlinden A, Hesta M, Millet S, et al. (2006): Food allergy in dogs and cats: A review. Crit Rev Food Sci Nutr, 46, 259– 273
Allergen specific IgE determination by in vitro allergy test in head and facial feline dermatitis: A pilot study
Abstract
Pruritus is one of the most common clinical findings in cats which have hypersensitivity on head and face regions.
The purpose of this small pilot study was to verify underlying causes of pruritus in cats with head and facial dermatitis by using in vitro
Veterinary Polycheck allergy tests which specifically detect Immunoglobulin E (IgE) concentrations against 20 different allergens. Ten
cats were introduced to the clinic with varying degrees of head and facial dermatitis along with primary/secondary skin lesions and
pruritus. At first, haematological, parasitological, microbiological and clinical examinations were performed. Six healthy cats without
dermatitis (neither infection nor hypersensitivity) were also evaluated as a control group. Afterwards, 0.2 ml of blood was taken from
all cats for specific IgE analysis against 20 different allergens. Regarding allergen specific IgE levels (kU/l) in cats with head/facial
dermatitis and in healthy cats, in vitro tests gave a positive reaction most frequently against flea, Acarus siro, D. farinae, Ragweed
(Ambrosia), Lambs quarter and Tyrophagus. There was a statistical significance between two groups for all allergens as follows;
Lepidoglyphus (p=0.031), Alternaria/Cladosporium (p=0.011), Stinging nettle (p=0.011) Lambs quarter (p=0.031), Sorrel (p=0.003)
and flea (Ctenocephalides) (p=0.031). In the present study, all positive reactions on the Polycheck test were thought to indicate
underlying allergens of facial/head dermatitis in cats. It has to be mentioned that, in vitro allergy tests cannot be used as a sole method
for distinguishing hypersensitivity from healthy cats due to the clinically irrelevant findings regarding morphology in healthy cats.
Positive reactions in healthy cats might indicate a subclinical hypersensitivity state or the requirement for investigating other relevant
factors.
Keywords
References
- 1. Belova S, Wilhelm S, Linek M et al. (2012): Factors affecting allergen-specific IgE serum levels in cats. Can J Vet Res, 76, 45–51.
- 2. DeBoer DJ (2016): Feline Facial Dermatoses. South Euro Vet Conf, Granada, Spain, p. 45.
- 3. Diesel A, DeBoer DJ (2011): Serum allergen-specific immunoglobulin E in atopic and healthy cats: comparison of a rapid screening immunoassay and complete-panel analysis. Vet Dermatol, 22, 39-45.
- 4. Foster AP (2002): Diagnosing and treating feline atopy. Vet Med Us, 97, 226-229.
- 5. Foster AP, O'Dair HA (1993): Allergy Testing for Skin Disease in the Cat. In Vivo vs In Vitro Tests, 4, 111–115.
- 6. Foster AP, O'Dair HA, DeBoer DJ (1997): Allergenspecific IgG antibodies in cats with allergic skin disease. Res in Vet Sci, 63, 239-243.
- 7. Gilbert S, Halliwell REW (2005): The effects of endoparasitism on the immune response to orally administred antigen in cats. Vet Immunol Immunopath, 106, 113–120.
- 8. Gross TL, Ihrke PJ, Walder EJ et al. (2005): Spongiotic and vesicular diseases of the epidermis. Facial dermatitis of persian and himalayan cats. 112-115. In: LG Thelma, JI Peter, JW Emily, K Verena (Eds), Skin diseases of the dog and cat. Clinical and histopathologic diagnosis. Blackwell, Oxford.
- 9. Guaguere E, Prelaud PA (1999): Practical guide to feline dermatology. Merial, New York.
- 10. Guilford WG, Jones BR, Markwell PJ, et al. (2001): Food hypersensitivity in cats with chronic idiopathic gastrointestinal problems. J Vet Int Med, 15, 7–13.
- 11. Hamilton RG, Williams PB (2010): Human IgE antibody serology: A primer for the practicing North American allergist/immunologist. J Allergy Clin Immunol, 126, 33– 38.
- 12. Helmer M, Epe C, Mueller RS (2008): The effect of helminth administration on caninne AD: A pilot study. Vet Dermatol, 19, 33.
- 13. Hill PB, DeBoer DJ (2001): The ACVD task force on canine atopic dermatitis (IV): environmental allergens. Vet Immunol Immunopath, 81, 169–186.
- 14. Hobi S, Linek M, Marignac G, et al. (2011): Clinical characteristics and causes of pruritus in cats: a multicentre study on feline hypersensitivity-associated dermatoses. Vet Dermatol, 22, 406–413.
- 15. Kim HJ, Kang MH, Park HM (2011): Common allergens of atopic dermatitis in dogs: comparative findings based on intradermal tests. J Vet Sci, 12, 287–290.
- 16. Linden CC, Misiak RT, Wegienka G, et al. (2011): Zoratti EM. Analysis of allergen specific IgE cutpoints to cat and dog in the suburban Detroit Childhood Allergy Study. Ann Allergy Asthma Immunol, 106, 153–158.
- 17. Locke PH, Harvey RG, Mason IS (1993): Manual of small animal dermatology. British Small Animal Veterinary Association, Gloucestershire.
- 18. Loft KE, Pedersen K (2007): The presence of pollen and house dust mite allergen-specific IgE in serum of 15 SPF cats and prevalence of house dust mites allergens (Dermatophagoides pteronyssinus1, Dermatophagoides farinae1, and mite group 2) in their microenvironement. Vet Dermatol, 18, 184.
- 19. Loft KE, Rosser EJJ (2010): Group 1 and 2 Dermatophagoides house dust mite allergens in the microenvironment of cats. Vet Dermatol, 21, 152–158.
- 20. Marsella R, Girolomoni G (2009): Canine models of atopic dermatitis: a useful tool with untapped potential. J Invest Dermatol, 129, 2351-2357.
- 21. MCall CA, Steadmann KE, Bevier DE, et al. (1997): Correlation of feline IgE, determined by FcEpsilonR1alfabased ELISA technology, and IDST to Ctenocephalides felis salivary antigens in a feline model of flea bite allergic dermatitis. Suppl to Comp Cont Edu Pract Vet, 3, 29–32.
- 22. Moncayo AL, Cooper PJ (2006): Geohelminth infections: Impact on allergic diseases. International J Bioch Cell Biol, 38, 1031–1035.
- 23. Moriello KA (2001): Case report: Feline atopy in three littermates. Vet Dermatol, 12, 177-181.
- 24. Moriello KA, Masom I (1995): Handbook of small animal dermatology. Elsevier Science Ltd, Oxford.
- 25. Mueller RS, Janda J, Jensen-Jarolim E, et al. (2016): Allergens in veterinary medicine. Allergy, 71, 27-35.
- 26. Nagata M, Rosenkrantz W (2013): Cutaneous viral dermatoses in dogs and cats. Comp Cont Edu Pract Vet, 35, 1-6.
- 27. Roosje PJ, Koeman JP, Thepen T, et al. (2004): Mast cells and eosinophils in feline allergic dermatitis: a qualitative and quantitative analysis. J Comp Path, 131, 61– 69.
- 28. Sampson HA, Ho DG (1997): Relationship between foodspecific IgE concentrations and the risk of positive food challenges in children and adolescents. J Allergy Clin Immunol, 100, 444–451.
- 29. Schenkel M, Bigler B, Jungi T (2000): The use of fluorescein for intradermal skin testing in cats. Vet Dermatol, 11, 14-40.
- 30. Schleifer SG, Willemse T (2003): Evaluation of skin test reactivity to environmental allergens in healthy cats and cats with atopic dermatitis. Am J Vet Res, 64, 773–778.
- 31. Scott DW, Miller WH, Griffin CE (2001): Small Animal Dermatology. W.B. Saunders Company, Philadelphia.
- 32. Simpson A, Soderstrom L, Ahlstedt S, et al. (2005): IgE antibody quantification and the probability of wheeze in preschool children. J Allergy Clin Immunol, 116, 744–749.
- 33. Szczepanik M, Pomorska D, Wilkołek P (2016): Diagnostic approach to atopy in cats. Bullet Vet Inst Pul, 52, 477-480.
- 34. Taglinger K, Helps CR, Day MJ, et al. (2005): Measurement of serum immunoglobulin E (IgE) specific for house dust mite antigens in normal cats and cats with allergic skin disease. Vet Immunol Immunopath, 105, 85- 93.
- 35. Verlinden A, Hesta M, Millet S, et al. (2006): Food allergy in dogs and cats: A review. Crit Rev Food Sci Nutr, 46, 259– 273
There are 35 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Article |
| Authors | |
| Publication Date | November 9, 2018 |
| Published in Issue | Year 2018Volume: 65 Issue: 4 |