Research Article
Year 2020,
Volume: 67 Issue: 2, 127 - 131, 03.03.2020
Abstract
References
- 1. Alsemgeest SPM, Kalsbeek HC, Wensing T, et al (1994): Concentrations of serum amyloid-a (SAA) and haptoglobin (Hp) as parameters of inflammatory diseases in cattle. Vet Quart, 16, 21-23.
- 2. Ames TR (1997): Dairy Calf Pneumonia. The disease and its impact. Vet Clin North Am Food Anim Pract, 13, 379-391.
- 3. Bryson DG, McNulty MS, McCracken RM (1983): Ultrastructural features of experimental parainfluenza type 3 virus pneumonia in calves. J Comp Pathol, 93, 397-414.
- 4. Coskun A, Guzelbektes H, Simsek A, et al (2012): Haptoglobin and SAA concentrations and enzyme activities in bronchoalveolar lavage fluids from calves with bronchopneumonia. Revue Méd Vét, 163, 615-620.
- 5. Coyne DW (2011): Hepcidin: clinical utility as a diagnostic tool and therapeutic target. Kidney Int, 80, 240-244.
- 6. Eckersall PD, Bell R (2010): Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine. Vet J, 185, 23-27.
- 7. Erkilic EE, Erdogan HM, Ogun M, et al (2016): Relationship between hepcidin and oxidant/antioxidant status in calves with suspected neonatal septicemia Vet World, 9, 1238-1241.
- 8. Falzacappa MVV, Muckenthaler MU (2005): Hepcidin: iron-hormone and anti-microbial peptide. Gene, 364, 37–44.
- 9. Fry MM, Liggett JL, Baek SJ (2004): Molecular cloning and expression of canine hepcidin. Vet Clin Path, 33, 223-227.
- 10. Joshi V, Gupta VK, Bhanuprakash AG, et al (2018): Haptoglobin and serum amyloid A as putative biomarker candidates of naturally occurring bovine respiratory disease in dairy calves. Microb Pathogenesis, 116, 33-37.
- 11. Kabu M, Elitok B, Kucukkurt I (2016): Decetion of serum amyloid-A concentration in the calf clinically diagnosed with pneumonia, enteritis and pneumoenterites. Ciência Rural, 46, 293-299.
- 12. Kabu M, Sayın Z (2016): Concentrations of serum amyloid A, haptoglobin, tumour necrosis factor and interleukin-1 and -6 in Anatolian buffaloes naturally infected with dermatophytosis. Vet Med-Czech, 61, 133-135.
- 13. Kemna E, Pickkers P, Nemeth E, et al (2005): Timecourse analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS. Blood, 106, 1864-1866.
- 14. Krause A, Neitz S, Magert HJ, et al (2000): LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett, 480, 147–150.
- 15. Murata H, Shimada N, Yoshioka M (2004): Current research on acute phase proteins in veterinary diagnosis. Vet J, 168, 28-40.
- 16. Nemeth E, Valore EV, Territo M, et al (2003): Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood, 101, 2461-2463.
- 17. Niine T, Peetsalu K, Nieminen M, et al (2017): Giardia and Cryptosporidium infections in neonatal reindeer calves: Relation to the acute phase response. Comp Immunol Microb, 54, 45-50.
- 18. Orro T, Jacobsen S, LePage JP, et al (2008): Temporal changes in serum concentrations of acute phase proteins in newborn dairy calves. Vet J, 176, 182-187.
- 19. Petersen HH, Nielsen JP, Heegaard PMH (2004): Application of acute phase protein measurements in veterinary clinical chemistry. Vet Res, 35, 163-187.
- 20. Sahinduran Ş, Kale M, Kıyıcı R, et al (2017): Some acute phase proteins and hepcidin levels in single and dual infection with BVD and BHV-1. MAKÜ Sag Bil Enst Derg, 5, 115-123.
- 21. Svensson C, Lundborg K, Emanuelson U, et al (2003): Morbidity in Swedish dairy calves from birth to 90 days of age and individual calf-level risk factors for infectious diseases. Prev Vet Med, 58, 179–197.
- 22. Waltner-Toews D, Martin SW, Meek AH (1978): Dairy calf management, morbidity and mortality in Ontario Holstein herds. II: Age and seasonal patterns. Prev Vet Med, 4, 125-135.
- 23. Wessling-Resnick M (2010): Iron Homeostasis and the Inflammatory Response. Annu Rev Nutr, 30, 105–122.
- 24. Yılmaz O, Gökçe G (2017): Sığırlarda enfeksiyöz solunum sistemi hastalıkları kompleksinde (brdc) klinik, hematoloji, biyokimya, oksidatif stres, akut faz proteinler üzerinde araştırmalar. Ataturk Universitesi Vet Bil Derg, 12, 34-44.
Determination of serum amyloid A, haptoglobin and hepcidin levels in calves with endemic viral pneumonia
Abstract
The aim of this study was to investigate serum amyloid A, haptoglobin and hepcidin levels in respiratory infections caused by various viral agents in calves. Pneumonia is an infectious or non-infectious disease affecting the lungs of all animals, and during the inflammation, blood levels of acute phase proteins increase rapidly. Hepcidin is a hormone that has many functions and is known as type II acute phase reactant. The blood samples were collected from a total of 20 calves to form the study group. The control group consisted of 10 healthy animals. Sera were analyzed with ELISA for antigen detection. According to the results, Bovine herpesvirus type-1 (BHV-1) was positive in 3 calves, Bovine viral diarrhea virus (BVDV) was positive in 3 calves, Bovine respiratory syncytial virus (BRSV) was positive in 1 calf, and Bovine parainfluenza virus type 3 (BPI3) was positive in 1 calf. Adenovirus infection was detected in 5 animals together with other viruses. Mixed infections were observed in 12 calves. Haptoglobin, serum amyloid A and hepcidin values were measured in sera. According to the results, statistically significant differences were observed between the two groups for the haptoglobin (P<0.01), serum amyloid A (P<0.05) and hepcidin (P<0.05). It was concluded that these parameters can be used to support the diagnosis of respiratory infections of the calves.
References
- 1. Alsemgeest SPM, Kalsbeek HC, Wensing T, et al (1994): Concentrations of serum amyloid-a (SAA) and haptoglobin (Hp) as parameters of inflammatory diseases in cattle. Vet Quart, 16, 21-23.
- 2. Ames TR (1997): Dairy Calf Pneumonia. The disease and its impact. Vet Clin North Am Food Anim Pract, 13, 379-391.
- 3. Bryson DG, McNulty MS, McCracken RM (1983): Ultrastructural features of experimental parainfluenza type 3 virus pneumonia in calves. J Comp Pathol, 93, 397-414.
- 4. Coskun A, Guzelbektes H, Simsek A, et al (2012): Haptoglobin and SAA concentrations and enzyme activities in bronchoalveolar lavage fluids from calves with bronchopneumonia. Revue Méd Vét, 163, 615-620.
- 5. Coyne DW (2011): Hepcidin: clinical utility as a diagnostic tool and therapeutic target. Kidney Int, 80, 240-244.
- 6. Eckersall PD, Bell R (2010): Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine. Vet J, 185, 23-27.
- 7. Erkilic EE, Erdogan HM, Ogun M, et al (2016): Relationship between hepcidin and oxidant/antioxidant status in calves with suspected neonatal septicemia Vet World, 9, 1238-1241.
- 8. Falzacappa MVV, Muckenthaler MU (2005): Hepcidin: iron-hormone and anti-microbial peptide. Gene, 364, 37–44.
- 9. Fry MM, Liggett JL, Baek SJ (2004): Molecular cloning and expression of canine hepcidin. Vet Clin Path, 33, 223-227.
- 10. Joshi V, Gupta VK, Bhanuprakash AG, et al (2018): Haptoglobin and serum amyloid A as putative biomarker candidates of naturally occurring bovine respiratory disease in dairy calves. Microb Pathogenesis, 116, 33-37.
- 11. Kabu M, Elitok B, Kucukkurt I (2016): Decetion of serum amyloid-A concentration in the calf clinically diagnosed with pneumonia, enteritis and pneumoenterites. Ciência Rural, 46, 293-299.
- 12. Kabu M, Sayın Z (2016): Concentrations of serum amyloid A, haptoglobin, tumour necrosis factor and interleukin-1 and -6 in Anatolian buffaloes naturally infected with dermatophytosis. Vet Med-Czech, 61, 133-135.
- 13. Kemna E, Pickkers P, Nemeth E, et al (2005): Timecourse analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS. Blood, 106, 1864-1866.
- 14. Krause A, Neitz S, Magert HJ, et al (2000): LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett, 480, 147–150.
- 15. Murata H, Shimada N, Yoshioka M (2004): Current research on acute phase proteins in veterinary diagnosis. Vet J, 168, 28-40.
- 16. Nemeth E, Valore EV, Territo M, et al (2003): Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood, 101, 2461-2463.
- 17. Niine T, Peetsalu K, Nieminen M, et al (2017): Giardia and Cryptosporidium infections in neonatal reindeer calves: Relation to the acute phase response. Comp Immunol Microb, 54, 45-50.
- 18. Orro T, Jacobsen S, LePage JP, et al (2008): Temporal changes in serum concentrations of acute phase proteins in newborn dairy calves. Vet J, 176, 182-187.
- 19. Petersen HH, Nielsen JP, Heegaard PMH (2004): Application of acute phase protein measurements in veterinary clinical chemistry. Vet Res, 35, 163-187.
- 20. Sahinduran Ş, Kale M, Kıyıcı R, et al (2017): Some acute phase proteins and hepcidin levels in single and dual infection with BVD and BHV-1. MAKÜ Sag Bil Enst Derg, 5, 115-123.
- 21. Svensson C, Lundborg K, Emanuelson U, et al (2003): Morbidity in Swedish dairy calves from birth to 90 days of age and individual calf-level risk factors for infectious diseases. Prev Vet Med, 58, 179–197.
- 22. Waltner-Toews D, Martin SW, Meek AH (1978): Dairy calf management, morbidity and mortality in Ontario Holstein herds. II: Age and seasonal patterns. Prev Vet Med, 4, 125-135.
- 23. Wessling-Resnick M (2010): Iron Homeostasis and the Inflammatory Response. Annu Rev Nutr, 30, 105–122.
- 24. Yılmaz O, Gökçe G (2017): Sığırlarda enfeksiyöz solunum sistemi hastalıkları kompleksinde (brdc) klinik, hematoloji, biyokimya, oksidatif stres, akut faz proteinler üzerinde araştırmalar. Ataturk Universitesi Vet Bil Derg, 12, 34-44.
There are 24 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Article |
| Authors | |
| Publication Date | March 3, 2020 |
| Published in Issue | Year 2020Volume: 67 Issue: 2 |