Research Article
Year 2021,
Volume: 68 Issue: 1, 27 - 32, 25.12.2020
Abstract
References
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- 2. Grisneaux E, Pibarot P, Dupuis J, et al (1999): Comparison of ketoprofen and carprofen administered prior to orthopedic surgery for control of postoperative pain in dogs. J Am Vet Med Assoc, 215, 1105-1110.
- 3. Holton LL, Scott EM, Nolan AM, et al (1998): Relationship between physiological factors and clinical pain in dogs scored using s numeric rating scale. J Small Anim Pract, 39, 469-474.
- 4. Kar P (2016): A comparative study between epidural butorphanol with bupivacaine and bupivacaine alone for intra-operative and post-operative analgesia in lower limb orthopaedic surgeries. Int J Res Med Sci, 4, 4251-4255.
- 5. Kona-Boun JJ, Cuvelliez S, Troncy E (2006): Evaluation of epidural administration of morphine or morphine and bupivacaine for postoperative analgesia after premedication with an opioid analgesic and orthopedic surgery in dogs. J Am Vet Med Assoc, 229, 1103-1112.
- 6. Mathews KA (2000): Pain assessment and general approach to management. Vet Clin North Am Small Anim Pract, 30, 729-755.
- 7. McMurphy R (1993): Postoperative epidural analgesia. Vet Clin North Am Small Anim Pract, 23,703-716.
- 8. Mich PM, Hellyer PW (2008): Objective, Categoric Methods for Assessing Pain and Analgesia. 78-109. In: JS Gaynor, WW Muir (Eds), Handbook of Veterinary Pain Management (2nd ed). Mosby, St. Louis.
- 9. Odette O, Smith LJ (2013): A comparison of epidural analgesia provided by bupivacaine alone, bupivacaine + morphine, or bupivacaine + dexmedetomidine for pelvic orthopedic surgery in dogs. Vet Anaesth Analg, 40, 527-536.
- 10. Pekcan Z, Koc B (2010): The post-operative analgesic effects of epidurally administered morphine and transdermal fentanyl patch after ovariohysterectomy in dogs. Vet Anaesth Analg, 37, 557-565.
- 11. Plumb DC (2002): Butorphanol tartrate. 116-119. In: DC. Plumb (Ed), Veterinary Drug Handbook (4th ed). Iowa State Press, USA.
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- 13. Smith LJ (2015): Normal Values for Anesthetized Patients. 119-122. In: LJ Smith (Ed), Questions and Answers in Small Animal Anaesthesia (1st ed). Wiley Blackwell, UK.
- 14. Smith N (2008): Butorphanol: a double-blind evaluation in postoperative patients with moderate or severe pain. Can J Anaesth, 21, 600-610.
- 15. Trim CM (1983): Cardiopulmonary effects of butorphanol tartrate in dogs. Am J Vet Res, 44,329-331
- 16. Troncy E, Besner GJ, Charbonneau R, et al (1996): Pharmacokinetics of epidural butorphanol in isoflurane anaesthetized dogs. J Vet Pharmacol Therap, 19, 268-273.
- 17. Troncy E, Junot S, Keroack S, et al (2002): Resuts of preemptive epidural administration of morphine with or without bupivacaine in dogs and cats undergoing surgery: 265 cases (1997-1999). J Am Vet Med Assoc, 221, 666-672.
- 18. Valverde A (2008): Epidural analgesia and anaesthesia in dogs and cats. Vet Clin North Am Small Anim Pract, 38, 1205-1230.
- 19. Wheeler M, Oderda GM, Ashburn MA, et al (2002): Adverse events associated with postoperative opioid analgesia: a systematic review. J Pain. 3, 159-180.
Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs
Abstract
The aim of this study was to compare the postoperative analgesic effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine in hind limb and pelvic orthopedic operations in dogs. Three groups each containing 10 dogs were formed. Through the lumbosacral space, group B was administered bupivacaine, 1 mg kg-1; group BB was administered bupivacaine, 1 mg kg-1 and butorphanol, 0.25 mg kg-1; and group BM was administered bupivacaine, 1 mg kg-1 and morphine, 0.1 mg kg-1. Anaesthesia was induced with diazepam (0.2 mg kg-1) and propofol (5 mg kg-1) and maintenance with isoflurane in oxygen. Pain assessment was performed with the University of Melbourne Pain Scale (UMPS) by a blinded observer. Plasma cortisol levels were measured preoperatively and postoperatively. Postoperative pain scores were significantly lower at 2 hours in the group BM, and at 8 and 12 hours in the groups BB and BM compared to the group B (P=0.007). Group BM had a lower plasma cortisol level than the group B at 2 hours (P=0.002). Bupivacaine-butorphanol and bupivacaine-morphine use were shown to provide longer analgesia in the postoperative period; and the epidural administration of bupivacaine-butorphanol and bupivacaine-morphine was considered to be potentially useful in clinical practice.
Keywords
References
- 1. Gaynor JS, Muir WW (2009): Handbook of Veterinary Pain Managmement (2nd ed). Mosby, USA.
- 2. Grisneaux E, Pibarot P, Dupuis J, et al (1999): Comparison of ketoprofen and carprofen administered prior to orthopedic surgery for control of postoperative pain in dogs. J Am Vet Med Assoc, 215, 1105-1110.
- 3. Holton LL, Scott EM, Nolan AM, et al (1998): Relationship between physiological factors and clinical pain in dogs scored using s numeric rating scale. J Small Anim Pract, 39, 469-474.
- 4. Kar P (2016): A comparative study between epidural butorphanol with bupivacaine and bupivacaine alone for intra-operative and post-operative analgesia in lower limb orthopaedic surgeries. Int J Res Med Sci, 4, 4251-4255.
- 5. Kona-Boun JJ, Cuvelliez S, Troncy E (2006): Evaluation of epidural administration of morphine or morphine and bupivacaine for postoperative analgesia after premedication with an opioid analgesic and orthopedic surgery in dogs. J Am Vet Med Assoc, 229, 1103-1112.
- 6. Mathews KA (2000): Pain assessment and general approach to management. Vet Clin North Am Small Anim Pract, 30, 729-755.
- 7. McMurphy R (1993): Postoperative epidural analgesia. Vet Clin North Am Small Anim Pract, 23,703-716.
- 8. Mich PM, Hellyer PW (2008): Objective, Categoric Methods for Assessing Pain and Analgesia. 78-109. In: JS Gaynor, WW Muir (Eds), Handbook of Veterinary Pain Management (2nd ed). Mosby, St. Louis.
- 9. Odette O, Smith LJ (2013): A comparison of epidural analgesia provided by bupivacaine alone, bupivacaine + morphine, or bupivacaine + dexmedetomidine for pelvic orthopedic surgery in dogs. Vet Anaesth Analg, 40, 527-536.
- 10. Pekcan Z, Koc B (2010): The post-operative analgesic effects of epidurally administered morphine and transdermal fentanyl patch after ovariohysterectomy in dogs. Vet Anaesth Analg, 37, 557-565.
- 11. Plumb DC (2002): Butorphanol tartrate. 116-119. In: DC. Plumb (Ed), Veterinary Drug Handbook (4th ed). Iowa State Press, USA.
- 12. Rijnberk A, Kooistra HS (2010): Adrenals. 61-93. In: A Rijnberk, (Ed), Clinical Endocrinology of Dogs and Cats: An Illustrated Text (2nd Ed). Schlütersche, Hannover.
- 13. Smith LJ (2015): Normal Values for Anesthetized Patients. 119-122. In: LJ Smith (Ed), Questions and Answers in Small Animal Anaesthesia (1st ed). Wiley Blackwell, UK.
- 14. Smith N (2008): Butorphanol: a double-blind evaluation in postoperative patients with moderate or severe pain. Can J Anaesth, 21, 600-610.
- 15. Trim CM (1983): Cardiopulmonary effects of butorphanol tartrate in dogs. Am J Vet Res, 44,329-331
- 16. Troncy E, Besner GJ, Charbonneau R, et al (1996): Pharmacokinetics of epidural butorphanol in isoflurane anaesthetized dogs. J Vet Pharmacol Therap, 19, 268-273.
- 17. Troncy E, Junot S, Keroack S, et al (2002): Resuts of preemptive epidural administration of morphine with or without bupivacaine in dogs and cats undergoing surgery: 265 cases (1997-1999). J Am Vet Med Assoc, 221, 666-672.
- 18. Valverde A (2008): Epidural analgesia and anaesthesia in dogs and cats. Vet Clin North Am Small Anim Pract, 38, 1205-1230.
- 19. Wheeler M, Oderda GM, Ashburn MA, et al (2002): Adverse events associated with postoperative opioid analgesia: a systematic review. J Pain. 3, 159-180.
There are 19 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Article |
| Authors | |
| Publication Date | December 25, 2020 |
| Published in Issue | Year 2021Volume: 68 Issue: 1 |
