A virus disease of man and animals characterized by intranuclear and intracytoplasmic inelusion bodies in greatly hypertrophied
ce lls primarily in the salivary glands and several organs was described many years ago.
Strains of the vırus are species-specific, although the similarity
of the morphologie changes they produce suggests that theyare biologically elosely relatcd.
it is now well recognized that there exist in man, monkey and
seveal rodents elosdy related viruses called cytomegaloviruse~, also
salivary gland, submaxillary gland, and eytomegalic inelusion
disease viruses which may lie dormant in the salivary glands, but
are capable of causing fatal generalized infection in guinea pigs.
A generalized blood dyscrasia, congenital defects such as microcephaly, cerebral cakification and hepatosplenomcgaly has been
noted in infants by a number of investigators 3, ıı, 1
4
• Salivary
gland disease İn a 4-week-old dog with degeneration of the ductal
epithdium of the submaxyllary gland and eosinophilic intranuelear
inelusion bodies was reported by Haberman at all 4. This is probbably the first recorded case of domesticated animals.
Primary Language | English |
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Subjects | Veterinary Surgery |
Journal Section | Research Article |
Authors | |
Publication Date | January 1, 1964 |
Published in Issue | Year 1964Volume: 11 Issue: 03.04 |