Ankara Üniversitesi Veteriner Fakültesi Dergisi

Abstract

Uremia was peiformed ligaturing the both ureters in three
healthy dogs. One dog (Dog 1) was used as control, and dialysis was not applied. He was kept till he died. In the other two dogs (Dog 2 and Dog 3), peritoneal dialysis were used as an altemative treatment for acute renal failure using
Stylet-Catheter. Before the experimentations, complate clinical examination,
hemogram and serum urea nitrogen, serum creatinin, serum chloride, serum
potassium and serum sodium concentrations were peiformed. In Dog 1, above examinations and measurements were detected at 6, 24, 30, 48 and 54 hOUfS
and he died at 60 hours after surgical operation. In the Dog 2 and Dog 3, therapy with peritoneal dialysis was started at 48 hours after surgical operation.
In these dogs were at this point ,.!letected uremia, hypercreatiniıı concentrations
in blood, hypochloremia, Iryperkalemia and hyponatremia. The dogs were dehydrated and showed CNS depression, a1lOrexia, inaeasing reluctance to walk.
Dialysis was done for 15 times in Dog 2 and 20 times in Dog 3. During the
peritoneal dialysis, blood samples and perıtoneal dia()'sate samples were collected at the time of 5, ıo, 15 and 20 dialysis. At the md of the peritoneal dialysis,
botlı dogs became alert and stood. Whereas aeatinin and B UN concentrations
were slightlyhigher than the normal values in Dog 2, blood clıemistryand electrolyte values were normal in Dog 3.